Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.35 (matrix metalloproteinase 9)
 2,207 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
matrix metalloproteinase 9 1107
MMP9 537
matrix metalloproteinase 2 531
MMP-9 484
matrix metalloproteinase 328
collagen 303
MMP-2 252
Mol 171
metalloproteinase 148
collagenase 147
MMP-1 137
EPA 137
Sep 135
stromelysin 134
MMP-3 113
MMP 107
TIMP-2 102
cytokine 96
tumor necrosis factor 91
vascular endothelial growth factor 84
fibronectin 79
tissue inhibitor of metalloproteinases 67
TNF 59
lipopolysaccharide 58
matrilysin 54
urokinase-type plasminogen activator 53
IL-6 52
E-cadherin 48
IL-8 47
cathepsin K 45
plasminogen 44
chemokine 39
AP-1 39
elastin 37
p38 37
insulin 36
TIMP 35
ERK1 35
epidermal growth factor 34
VEGF 34
p65 34
TNF-alpha 34
type I collagen 34
MMP-13 34
MMP-8 31
caspase-3 30
ERK 30
collagenase-3 30
tissue inhibitor of metalloproteinase 1 29
THP 29
MAPK 29
tartrate-resistant acid phosphatase 28
PLA 28
MMP2 28
inducible nitric oxide synthase 26
extracellular signal-regulated kinase 26
MMP-7 26
superoxide dismutase 25
RANKL 25
AKT 24
p53 24
LPS 24
tumor necrosis factor alpha 24
neutrophil elastase 23
myeloperoxidase 23
epidermal growth factor receptor 23
osteosarcoma 22
interleukin-6 22
catenin 22
vimentin 20
CD44 20
casein 20
TIMP-3 20
MT1-MMP 20
cyclin D1 20
platelet-derived growth factor 19
EGF 19
SDS 19
TGF-beta 19
proliferating cell nuclear antigen 19
Bcl-2 18
interferon 18
PI3K 18
CD11b 17
IL-1 17
glycoprotein 17
interleukin 6 17
c-Jun 17
N-cadherin 17
catalase 16
transforming growth factor-beta 16
focal adhesion kinase 16
osteopontin 16
JNK 16
tissue plasminogen activator 16
alkaline phosphatase 16
metalloprotease 16
hemopexin 15
matrix metalloprotease 15
macrophage colony-stimulating factor 15
IL-10 15
plasminogen activator inhibitor-1 15
acid phosphatase 15
MMP-12 15
mast cell 15
urokinase plasminogen activator 15
CD14 15
COX-2 14
matrix metalloproteinase 1 14
cathepsin G 14
CXCL12 14
IL-1 beta 14
hepatocyte growth factor 14
CXCR4 14
histone 13
adhesion molecule 13
signal transducer and activator of transcription 3 13
proteoglycan 13
Matrix metalloproteinase 9 13
metalloelastase 13
smooth muscle actin 13
beta 1 12
nitric oxide synthase 12
thrombin 12
IFN 12
estrogen receptor 12
MEK 12
p38 mitogen-activated protein kinase 12
granulocyte 12
TLR4 12
type II collagen 12
Rho 11
lymphoid 11
stromelysin-3 11
serine protease 11
TNM 11
C-reactive protein 11
cyclooxygenase-2 11
tumor necrosis factor receptor 11
neutrophil gelatinase-associated lipocalin 11
tyrosine kinase 11
kit 11
IFN-gamma 11
HT-1080 11
membrane protein 10
STAT 10
CD34 10
MCP-1 10
vascular endothelium 10
mTOR 10
Ang II 10
RANTES 10
Cytokine 10
axonal 10
STAT3 10
angiotensin II 10
glutathione peroxidase 10
peroxisome proliferator-activated receptor 10
CD4 10
albumin 9
more...
Disease
tumor 432
cancer 400
carcinoma 96
metastases 95
breast cancer 92
tumor growth 66
stroke 64
tumor progression 60
melanoma 47
rheumatoid arthritis 42
diabetes 41
atherosclerosis 41
multiple sclerosis 38
prostate cancer 36
carcinogenesis 34
ischemia 33
plaque 33
tumorigenesis 33
MCF 29
squamous cell carcinoma 27
fibrosarcoma 27
adenocarcinoma 26
hypertension 26
myocardial infarction 24
Alzheimer's disease 24
osteosarcoma 24
chronic obstructive pulmonary disease 24
arthritis 23
colorectal cancer 22
osteoporosis 22
hepatocellular carcinoma 22
gastric cancer 20
asthma 20
lung cancer 19
leukemia 19
primary tumor 19
brain edema 19
SDS 19
cerebral ischemia 18
colon cancer 17
cornea 17
sepsis 17
sepsis 16
glioma 16
pancreatic cancer 14
tumor angiogenesis 14
pulmonary fibrosis 14
abdominal aortic aneurysm 13
ovarian cancer 13
uterus 13
obesity 13
autoimmune disease 13
encephalomyelitis 13
aggressiveness 12
non-small cell lung cancer 12
liver fibrosis 12
astrocytoma 12
periodontitis 11
osteoarthritis 11
emphysema 11
meningitis 11
HIV 10
Blocking 10
Evans 10
cardiovascular disease 9
epithelial ovarian cancer 9
glioblastoma 9
heart failure 9
coronary artery disease 8
pemphigoid 8
lung metastases 8
pneumonia 8
Parkinson's disease 8
renal failure 8
lymphoma 8
cirrhosis 8
idiopathic pulmonary fibrosis 8
mammary tumor 8
cervical cancer 7
preeclampsia 7
cold 7
acute myocardial infarction 7
B-cell lymphoma 7
lung carcinoma 7
Epstein 7
type 2 diabetes 7
bladder cancer 7
tuberculosis 7
HGF 7
neuropathy 6
diabetic retinopathy 6
diabetic nephropathy 6
glaucoma 6
immunodeficiency 6
subarachnoid hemorrhage 6
keratitis 6
bacterial meningitis 6
acute pancreatitis 6
peritonitis 6
MIP 6
blindness 6
bone disease 6
lung disease 6
proteinuria 5
Kawasaki disease 5
inflammatory bowel disease 5
Osteosarcoma 5
chronic pancreatitis 5
endometriosis 5
amyotrophic lateral sclerosis 5
chronic renal failure 5
infectious diseases 5
sarcoma 5
aggression 5
Adhesion 5
cognitive impairment 5
neutropenia 5
SCID 5
mimicry 5
colitis 5
liver metastases 5
AIDS 5
Osteosarcoma 5
PSS 5
dysplasia 5
choriocarcinoma 5
cholera 5
cystic fibrosis 5
glioblastoma multiforme 5
liver cancer 5
hyperglycemia 5
neuroblastoma 4
infertility 4
retinoblastoma 4
respiratory failure 4
multiple myeloma 4
cerebral infarction 4
vascular disease 4
renal cell carcinoma 4
bone metastases 4
SEM 4
metastatic breast cancer 4
cardiomyopathy 4
Hypertrophic 4
solid tumor 4
metastatic melanoma 4
Mycobacterium 4
acute myeloid leukemia 4
abortion 4
endometrial cancer 4
hypercholesterolemia 4
premature rupture of membranes 4
dermatitis 4
Melanoma 4
liver cancer 4
Dermal 4
myelodysplastic syndrome 4
pertussis 3
transient ischemic attack 3
coronary heart disease 3
more...
Symptom
functional recovery 11
pain 11
anesthesia 6
respiratory distress 5
thinning 5
hyperoxia 3
seizures 3
hypothermia 3
swollen joints 2
splenomegaly 2
starvation 2
angina 2
collapse 2
dry eye 2
analgesia 2
dizziness 1
weakness 1
impaired motor coordination 1
cough 1
chest pain 1
overweight 1
ataxia 1
chronic cough 1
dystonia 1
abdominal pain 1
Central post-stroke pain 1
spasm 1
erythema 1
skin irritation 1
headache 1
acute stress 1
Drug
Gelatin 42
Dermatol 35
CSF 13
uPA 12
IFN-gamma 11
lysine 10
Gel 7
DNase I 7
Cardiovasc 7
ROS 6
Indomethacin 5
Asn 5
MAP 5
PTH 5
Batimastat 4
Doxycycline 4
G-CSF 4
Batimastat 4
Asthma 4
CaCl2 3
Amiloride 3
CaCl2 3
Simvastatin 3
Amiloride 3
Vitamin E 3
p75 3
vitamin E 3
CaCl2 3
IFN-beta 3
IL-2 2
ID2 2
TAT 2
lactose 2
Rutin 2
Propofol 2
Urokinase 2
Aliskiren 2
AZT 1
Magnesium sulfate 1
CTX 1
ROC 1
Methylprednisolone 1
CTT 1
Trocade 1
Artemether 1
Angiotensin II 1
Marimastat 1
Emodin 1
Lacidipine 1
PDL 1
-deoxyadenosine 1
NaI 1
Prednisolone 1
NaI 1
EPA 1
Gleevec 1
ICI 1
Lacidipine 1
Liarozole fumarate 1
Rituximab 1
Ketotifen 1
Retinoic acid 1
Rosiglitazone 1
Alliance 1
AraC 1
Paraffin 1
NaI 1
ascorbate 1
IL-1ra 1
ZnCl2 1
Ilomastat 1
Eptifibatide 1
Prinomastat 1
Argatroban 1
Emodin 1
CTX 1
Lactose 1
Cilostazol 1
Trilostane 1
Imatinib 1
Oxaprozin 1
Bortezomib 1
Growth hormone 1
BTC 1
Glide 1
TiO2 1
Avasimibe 1
MDS 1
Growth hormone 1
Hyperforin 1
ZnCl2 1
Captopril 1
Pronase 1
AZT 1
ABC 1
ADM 1
ETA 1
nitroglycerin 1
EPI 1
Leaf 1
Hyoscyamine 1
CTX 1
PCP 1
MRC 1
NaI 1
Prolastin 1
Monit 1
Fennel 1
Bevacizumab 1
Fructose 1
Monensin 1
Enzyme
matrix metalloproteinase 9 2207
matrix metalloproteinase 2 632
collagenase 232
MMP-3 167
MMP 159
interstitial collagenase 111
mitogen-activated protein kinase 110
urokinase-type plasminogen activator 67
ERK 52
cathepsin K 45
trypsin 38
plasmin 37
luciferase 31
peroxidase 30
tissue plasminogen activator 30
neutrophil elastase 29
elastase 29
protein kinase 28
superoxide dismutase 27
protein kinase C 25
focal adhesion kinase 23
catalase 21
caspase-3 20
macrophage elastase 17
alkaline phosphatase 16
neutrophil collagenase 16
MEK 16
cathepsin G 16
acid phosphatase 15
reverse transcriptase 13
CD10 12
thrombin 12
stromelysin-3 11
glutathione peroxidase 10
cathepsin B 9
collagenase 3 9
NADPH oxidase 9
NO synthase 8
proteasome 8
aspartate aminotransferase 8
NADPH oxidase 8
cathepsin D 8
chymase 7
phosphatidylinositol 3-kinase 7
phosphoinositide 3-kinase 7
alanine aminotransferase 7
ATPase 7
MIP 6
calcineurin 6
lactate dehydrogenase 5
RNase 5
RNase 5
tryptase 5
CD13 5
renin 4
ACS 4
PARP 4
chymotrypsin 4
GSK 4
TACE 4
AST 4
beta-glucuronidase 4
isocitrate dehydrogenase 3
thermolysin 3
cathepsin L 3
IKK 3
matrix metalloproteinase 10 3
carbonic anhydrase 3
ribonuclease 3
kallikrein 3
ribonuclease 3
tyrosine hydroxylase 3
RNA polymerase 3
NQO1 3
phosphorylase 3
beta-galactosidase 3
transcriptase 3
granzyme B 3
glutathione S-transferase 3
isocitrate dehydrogenase 3
phospholipase A2 2
PNGase F 2
phospholipase C 2
PKG 2
P-glycoprotein 2
ACE 2
caspase-8 2
histone acetyltransferase 2
DNase 2
lysozyme 2
citrate synthase 2
caspase-9 2
chitinase 2
TAT 2
creatine kinase 2
isopeptidase 2
chloramphenicol acetyltransferase 2
cathepsin S 2
aldose reductase 2
BAL 2
IgA protease 2
prostaglandin synthetase 2
furin 2
prostate-specific antigen 2
phosphodiesterase 2
TSP-1 2
NOS 2
IgA1 protease 2
pyruvate dehydrogenase 1
AMPK 1
meprin 1
topoisomerase 1
carboxypeptidase A 1
NADPH:quinone oxidoreductase 1
diacylglycerol kinase 1
topoisomerase 1
arginase 1
histidine decarboxylase 1
galactose-6-sulfatase 1
phosphatidylinositol 4-kinase 1
PDK1 1
sulfatase 1
cdc2 1
chondroitinase 1
deuterolysin 1
PIP kinase 1
pepsin 1
arylsulfatase 1
adamalysin 1
histidyl-tRNA synthetase 1
arylsulfatase A 1
leucine aminopeptidase 1
malate dehydrogenase 1
mu-calpain 1
pyruvate dehydrogenase 1
alanine aminopeptidase 1
CaMKII 1
transglutaminase 1
m-calpain 1
AMP-activated protein kinase 1
matriptase 1
pyruvate dehydrogenase 1
PAL 1
soluble epoxide hydrolase 1
aldehyde dehydrogenase 1
enolase 1
caspase-1 1
triphosphatase 1
protein phosphatase 2A 1
MCS 1
thromboplastin 1
DAT 1
p100 1
proprotein convertase 1
PCP 1
PAL 1
aconitase 1
matrilysin-2 1
Pla 1
prolyl hydroxylase 1
more...
Compound
Dec 151
Clin 95
DNA 90
acetate 88
oxygen 77
zinc 67
TNF 59
calcium 52
serine 42
water 39
MDA 34
glucose 33
nitric oxide 30
THP 29
THP 29
leucine 28
NH2 27
MTT 26
tyrosine 26
sodium 25
alanine 24
arginine 24
sulfate 23
Gly 23
lysine 22
cysteine 21
EDTA 20
Collagenase 20
EDTA 20
SDS 19
cAMP 18
PMA 15
Phe 15
Asp 15
threonine 14
PMA 14
Cereb 13
phosphate 13
methionine 13
Ile 12
hydrogen 12
His 12
Collagen 11
MEK 11
PGE2 10
TNM 10
PGE 10
Ang II 9
galactose 9
nitrogen 9
retinoic acid 9
proline 9
PEG 9
bromide 8
iron 8
PEG 7
SCC 7
glutamine 6
tryptophan 6
urea 6
TPA 6
TPA 6
CO2 6
copper 6
Indomethacin 5
titanium 5
Cardiol 5
tryptophan 5
silver 5
tryptophan 5
acrylamide 5
creatinine 5
ASA 5
tryptophan 5
Adriamycin 5
CAT 5
Curcumin 5
CAT 5
ATP 5
AMP 5
CAT 5
ADR 5
GMP 4
Melatonin 4
pyrrolidine 4
ACS 4
Vimentin 4
Progesterone 4
ACS 4
aldehyde 4
Serine 4
ethanol 4
N-acetylcysteine 4
acetic acid 4
Thrombin 4
homocysteine 4
glutamate 4
Doxycycline 4
Insulin 4
pyrimidine 4
TACE 4
MCP 4
pyrimidine 4
iodine 4
ADP 3
aldosterone 3
PGJ2 3
vinyl 3
NAD 3
Vitamin E 3
COX 3
Phorbol 3
nicotinamide 3
cadmium 3
Estrogen 3
retinol 3
cGMP 3
pyrrolidine 3
GSH 3
manganese 3
H2O2 3
Amiloride 3
Hematoxylin 3
asparagine 3
pyrene 3
TEM 3
potassium 3
prostaglandin J2 3
NAD 3
Dexamethasone 3
Optimal 3
fluorine 3
glutamic acid 3
CaCl2 3
dUTP 3
hyaluronic acid 3
Keratin 3
GSH 3
phenol 3
diacetate 3
Estrogen 3
ADP 3
ADP 3
GABA 2
27-Hydroxycholesterol 2
GABA 2
Metformin 2
2-hydroxyethyl 2
GTP 2
Fluvastatin 2
CoA 2
Propofol 2
Pioglitazone 2
DBA 2
pyridine 2
SET 2
bis(2-chloroethyl) 2
acridine 2
2-hydroxyethyl 2
DBA 2
more...