Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.3 (collagenase)
 18,340 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
T-cluster binding protein 10.8
procollagen alpha 1(I) chain 10.8
ZNF510 10.8
PRG-4 10.8
TCEAL2 10.8
collagenase 10.7
MMP-1 10.7
MMP-8 10.2
archaemetzincin-1 9.8
Endothelial collagen 9.8
Apoptotic peptidase activating factor 1 9.8
RAN binding protein 9 9.8
MMP1 protein 9.4
MMP-3 9.4
MMP-13 9.2
WISP3 protein 9.2
MMP-19 9.2
stromelysin 9.1
MMP-25 9.1
AB collagen 9.0
tissue inhibitor of metalloproteinases 8.9
MMP-10 8.8
Cas-interacting zinc finger protein 8.8
M12 family 8.8
AMZ1 8.8
collagen alpha 1(I) chain 8.8
TKT protein 8.8
LMF2 8.8
PLGL 8.6
MMP-7 8.6
TIMP 8.6
MT2-MMP 8.6
TIMP-2 8.6
MMP8 8.5
collagenase-3 8.5
MMP-11 8.5
Epithelial membrane protein 1 8.4
LRRC17 8.4
VI-3 8.4
5qNCA 8.4
type I collagen alpha 1 chain 8.4
MMP-27 8.4
Collagenase 3 8.4
endothelial collagen 8.4
MT1-MMP 8.2
Matrix metalloproteinase 1 8.2
TIMP-4 8.2
Cholesterol acyltransferase 8.2
TEL-2 8.2
F-box only protein 22 8.2
matrix metalloproteinase 10 8.2
MMD2 8.2
DERL3 8.2
macrophage expressed gene 1 8.2
TRIP8 8.2
N-Acetylglucosamine kinase 8.2
Wnt-13 8.2
Tissue factor pathway inhibitor-2 8.1
MMP-12 8.1
TIMP-3 8.1
matrix metalloproteinase 1 8.1
ADAMTS-4 8.1
matrilysin 8.0
MT4-MMP 8.0
aggrecanase-1 8.0
ATF2 protein 8.0
SPP-1 8.0
gp130-RAPS 8.0
metalloelastase 8.0
DEFA6 8.0
pro-alpha 1(II) collagen 8.0
MMP-2 7.9
Trypsin-2 7.9
MMP-9 7.8
Thioesterase II 7.8
CCC6 7.8
type XII collagen 7.8
hGRP 7.8
SERPINB11 7.8
EFHD2 7.8
more...
Disease
Other myeloid leukemia 9.8
LACH 9.2
Dendritic keratitis 9.2
Photodamaged skin 8.8
Mycoplasma arthritis 8.8
Vitreous liquefaction 8.4
Tendon calcification 8.4
BCDP 8.4
Myocardial hemorrhage 7.8
Tumor embolus 7.6
OASF 7.6
Psoriatic plaque 7.6
Ehlers-Danlos syndrome type VII 7.4
Elastolysis 7.4
Milwaukee shoulder 7.4
Medullary nephrocalcinosis 7.3
stage I renal cell carcinoma 7.3
Milwaukee shoulder 7.3
Biventricular hypertrophy 7.3
Dupuytren 7.3
Canine cutaneous histiocytoma 7.2
Tendinopathy 7.1
Congenital cutis laxa 7.1
Dupuytren's disease 7.0
Yoshida Sarcoma 7.0
Plantar fibromatosis 7.0
Lipodermatosclerosis 7.0
Chronic iron overload 6.9
Pulmonary cavitation 6.9
Hereditary nephritis 6.9
chronic skin ulcer 6.8
Acute esophagitis 6.8
Achilles tendinitis 6.7
Invasive bladder cancer 6.7
osteoblastic osteosarcoma 6.6
Peyronie's disease 6.6
Goodpasture's syndrome 6.6
Amyloid arthropathy 6.5
demineralization of bone 6.4
Mammary adenocarcinoma 6.4
cerebral hematoma 6.4
MYP3 6.4
Tendon disorders 6.3
metastatic parathyroid carcinoma 6.3
Pyostomatitis vegetans 6.3
Mastocytoma 6.2
Xeroderma pigmentosum group C 6.1
Round ligament 6.1
scleromalacia 6.1
EDS5 6.0
keratomalacia 6.0
Gastric infection 6.0
Recessive dystrophic epidermolysis bullosa 5.9
MPS IVB 5.8
EDC 5.7
Diabetic microangiopathy 5.7
Ligneous conjunctivitis 5.7
Kashin-Beck disease 5.6
AD5 5.6
Weber-Cockayne 5.6
Non-dipping 5.5
Limbal stem cell deficiency 5.5
pancreatic fibrosis 5.5
Brain lesion 5.5
prostate cancer stage 5.5
COL2A1 5.4
EB simplex 5.4
AAT2 5.4
Ehlers-Danlos syndrome type IV 5.4
recurrent neuroblastoma 5.4
Lack of insight 5.3
Alternating hemiplegia of childhood 5.3
Takahara 5.3
Achilles tendon pain 5.3
Root caries 5.3
Epidermolysis bullosa acquisita 5.3
epidermolysis bullosa 5.3
Junctional epidermolysis bullosa 5.2
Intrauterine adhesions 5.2
juvenile periodontitis 5.2
more...
Symptom
Hegar's sign 10.8
Goodell's sign 10.8
Central post-stroke pain 7.0
Quadriceps weakness 6.4
Procedural pain 6.2
Trembling 6.1
skin damage 5.8
musculoskeletal disability 5.2
autodigestion 4.8
disturbed balance 4.5
nerve pain 4.0
inanition 4.0
Joint hypermobility 3.8
Muscle soreness 3.6
scaly skin 3.3
swollen joints 3.3
Tenderness 3.2
Scratch 3.1
pedal edema 3.0
POA 2.7
functional recovery 2.6
Stepping 2.5
Fluctuation 2.5
hyperoxia 2.4
Stiffness 2.4
erythema 2.2
rigors 2.1
skin irritation 2.0
agitation 2.0
thinning 1.9
loss of balance 1.9
Spots 1.9
flushing 1.8
stomach pain 1.8
rundown 1.8
dry skin 1.8
Hudson 1.7
Decreased activity 1.7
Anoxia 1.7
muscle stiffness 1.5
tremor 1.5
bitter taste 1.3
arthralgia 1.3
HSA 1.2
chronic back pain 1.2
polyuria 1.2
sciatica 1.2
photophobia 1.1
back pain 1.0
dry eye 1.0
muscle cramps 0.9
neurological disability 0.9
DNA marker 0.9
knee pain 0.9
low back pain 0.8
eds 0.7
cachexia 0.6
Mills 0.4
fasciculation 0.4
collapse 0.4
starvation 0.4
hypothermia 0.4
shoulder pain 0.3
respiratory distress 0.3
incoordination -0.0
cerebellar ataxia -0.1
leg pain -0.2
pain -0.2
tense -0.3
polydipsia -0.3
stigma -0.4
tachypnea -0.6
Wind -0.6
angina -0.6
weakness -0.6
regurgitation -0.7
anesthesia -0.7
hepatomegaly -0.7
cancer pain -0.8
fatigue -0.9
more...
Drug
Tanomastat 10.8
Santyl 10.2
Trocade 9.8
Asiasarum root 9.2
Prinomastat 9.2
Potaba 8.6
Olaflur 8.2
Batimastat 7.9
Batimastat 7.9
Berberine sulfate 7.8
Indacrinone 7.4
Methacholine chloride 7.3
Travase 7.3
Trimegestone 7.2
Tolmetin sodium 7.0
Levophed 6.9
nonatetraenoic acid 6.9
Tesaglitazar 6.9
Arundic acid 6.9
Citrus unshiu peel 6.7
Marimastat 6.6
Ilomastat 6.5
Plasmanate 6.4
Gly-Tyr-Gly 6.4
Hyaluronidase 6.3
Gelatin 6.3
Hyaluronidase 6.2
Avasimibe 6.2
Chymopapain 6.2
DOXY 6.1
Gold sodium thiomalate 6.0
Dexamethasone sodium phosphate 6.0
Camostat mesilate 6.0
Hirudoid 6.0
Pronase 5.8
Sulfaphenazole 5.8
K201 5.7
Tiopronin 5.7
Pirprofen 5.7
Vibramycin 5.5
FML 5.5
balanced salt solution 5.4
Prolastin 5.4
uPA 5.4
Cilomilast 5.4
Iotrolan 5.3
Olomoucine 5.3
Sodium metabisulfite 5.3
Desmopressin acetate 5.3
Lumiracoxib 5.1
Solon 5.1
Aprotinin 5.0
Sodium ascorbate 5.0
Sesamol 4.9
Red ginseng 4.9
Chloramine T 4.9
Ioversol 4.9
Biltricide 4.9
Conray 4.8
Tiaprofenic acid 4.8
Oxfendazole 4.8
Nafamostat mesilate 4.8
Brij 96 4.8
Beraprost sodium 4.7
Metrizamide 4.7
Guanidine 4.7
Guanidine 4.7
Doxycycline 4.7
Cilostazol 4.7
Papain 4.6
CLS 4.6
Velban 4.6
Gabexate mesilate 4.5
Tannic acid 4.5
Adapalene 4.5
Isopaque 4.5
Ciglitazone 4.5
Hypaque 4.5
KGF 4.4
Omniscan 4.4
more...
Enzyme
collagenase 10.8
neutrophil collagenase 10.2
brachyurin 9.8
nucleoside N-ribosyltransferase 9.8
interstitial collagenase 9.7
MMP-3 9.5
collagenase 3 9.4
hypodermin C 8.9
chondroitin sulfate ABC endolyase 8.8
flavastacin 8.8
matrix metalloproteinase 10 8.4
hippurate hydrolase 8.2
aggrecanase-1 8.1
bacillolysin 8.0
keratan sulfate sulfotransferase 8.0
thermomycolase 8.0
proteinase yscD 8.0
macrophage elastase 7.9
matrix metalloproteinase 2 7.9
deuterolysin 7.8
stromelysin-3 7.7
MMP 7.5
matrix metalloproteinase 9 7.5
hyaluronidase 7.4
pepsin B 7.3
clostripain 7.2
hyaluronidase 7.1
atrolysin C 6.9
elastase 6.8
matrix metalloproteinase 14 6.6
cathepsin G 6.6
endo-alpha-N-acetylgalactosaminidase 6.6
pseudolysin 6.5
tail-specific protease 6.5
lysyl hydroxylase 6.5
chymopapain 6.4
vibriolysin 6.4
acylcarnitine hydrolase 6.4
chymopapain 6.3
type III procollagen 6.2
chondroitinase 6.2
streptopain 6.2
TACE 6.1
chondroitinase 6.1
GPH 6.0
thermolysin 6.0
cathepsin K 5.8
cathepsin V 5.8
hatching enzyme 5.7
thimet oligopeptidase 5.7
N-acetylgalactosaminidase 5.7
pepsin 5.6
lysyl oxidase 5.6
ficin 5.6
astacin 5.6
trypsin 5.6
carnosine synthetase 5.6
prolyl hydroxylase 5.6
carboxyl proteinase 5.5
IgA protease 5.4
GPI-specific phospholipase C 5.4
heparitinase I 5.4
galactosylhydroxylysyl glucosyltransferase 5.4
plasmin 5.4
fibrolase 5.3
DNase 5.3
chondroitin ABC lyase 5.3
phosphatidylethanolamine N-methyltransferase 5.3
neutrophil elastase 5.3
prolinase 5.2
pyroglutamyl peptidase II 5.2
urokinase-type plasminogen activator 5.2
deoxyribonuclease 5.2
CBPP 5.1
cathepsin B 5.1
prolidase 5.1
tetanus neurotoxin 5.1
glutamine transaminase K 5.1
deoxyribonuclease 5.1
chondroitinase AC 5.1
more...
Compound
F 2268 10.8
Collagenase 10.0
4-chloro-N-cyclohexylbenzamide 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
Z-Gly-Pro-Leu-Gly-Pro 9.5
Absinthin 9.2
Astringin 9.2
Aranciamycin 9.2
C15H26O 9.2
(+)-Syringaresinol 9.2
C14H11NO2 9.2
C15H26O 9.2
C15H26O 9.2
2,3,3-trichloroacrylamide 9.2
benzoyl isothiocyanate 8.9
C15H26O 8.8
Himachalol 8.8
C15H26O 8.8
Neryl acetate 8.8
alpha-Eudesmol 8.8
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol 8.4
C6H12N2O 8.4
Isosakuranetin 8.4
Picrotin 8.4
C20H24O6 8.4
C15H26O 8.4
Globulol 8.4
C15H26O 8.4
Azocoll 8.2
C15H26O2 8.2
Vernolide 8.2
Guaiol 8.0
Hydrangenol 8.0
Diphenyliodonium chloride 8.0
CH5N 8.0
Hinesol 8.0
Glycitin 8.0
Berberine sulfate 7.8
Sarkosyl NL 7.8
Berberine sulfate 7.8
I acid 7.6
2,6-diisopropylnaphthalene 7.6
3-bromo-4,5-dihydroxybenzaldehyde 7.6
GRP-1 7.6
Lupeol acetate 7.6
3-methylbutanamide 7.4
Alloxan monohydrate 7.3
2-mercaptoacetamide 7.3
(2-methoxyethoxy)acetic acid 7.3
Dithizone 7.2
Tetrahydroberberine 7.2
2,4,6-octatrienoic acid 7.2
Pivalone 7.2
Tetrahydroberberine 7.2
Jatrophone 7.2
N-Nitrosodiphenylamine 7.2
Tricetin 7.1
Didecyldimethylammonium chloride 7.1
Bornyl acetate 7.0
Actinonin 7.0
Bornyl acetate 7.0
Mycosporine 6.9
Pinane 6.9
1,4-diisocyanatobutane 6.9
D-Lysine 6.9
Z-Arg-Arg-NHMec 6.9
TMCA 6.8
Tectorigenin 6.8
Boswellic acid 6.7
Fucosterol 6.7
beta-Eudesmol 6.7
Fucosterol 6.6
7H-benzo[c]fluorene 6.6
more...