Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.24.3 (collagenase)
18,340 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein collagenase 13438 collagen 4986 MMP-1 3359 matrix metalloproteinase 1731 MMP-9 1380 MMP-2 1293 Sep 1232 MMP-3 1030 Mol 924 insulin 874 EPA 851 MMP-8 737 type I collagen 721 metalloproteinase 705 MMP-13 622 stromelysin 562 cytokine 550 fibronectin 533 TIMP-2 496 IL-6 464 hyaluronidase 446 tumor necrosis factor 399 TNF 396 MMP 372 tissue inhibitor of metalloproteinases 364 matrix metalloproteinase 2 332 AP-1 324 proteoglycan 303 SDS 301 p38 287 alkaline phosphatase 273 elastin 272 IL-1 269 MT1-MMP 265 albumin 247 IL-8 240 type II collagen 239 lipopolysaccharide 233 polypeptide 207 vascular endothelial growth factor 200 c-Jun 200 MMP-7 193 PLA 193 epidermal growth factor 190 TIMP 186 AMP 186 glycoprotein 183 urokinase-type plasminogen activator 178 ATP 175 MMP9 168 TNF-alpha 168 aggrecan 167 MAPK 164 glucagon 158 ERK 151 TGF-beta 145 interleukin-6 143 chymotrypsin 143 ERK1 139 serum albumin 135 JNK 133 casein 130 angiotensin II 116 parathyroid hormone 115 caspase-3 115 metalloprotease 115 COX-2 114 inducible nitric oxide synthase 112 transforming growth factor-beta 112 TIMP-3 110 plasminogen 110 thrombin 109 MMP-10 109 plasminogen activator inhibitor-1 109 DNase 109 smooth muscle actin 108 IL-1 beta 108 MMP-12 108 IL-10 107 lactate dehydrogenase 106 more...

Disease tumor 1187 cancer 1141 osteoarthritis 519 rheumatoid arthritis 424 diabetes 380 arthritis 355 SDS 301 carcinoma 241 periodontitis 220 atherosclerosis 213 plaque 210 stroke 207 melanoma 202 metastases 196 breast cancer 187 liver fibrosis 145 cold 130 tumor growth 127 ischemia 123 tumor progression 123 cornea 112 carcinogenesis 109 hepatocellular carcinoma 108 SEM 107 cirrhosis 102 hypertension 102 periodontal disease 101 adenocarcinoma 98 brain edema 95 uterus 92 GSH 88 squamous cell carcinoma 86 Dupuytren 76 obesity 76 hyperglycemia 75 fibrosarcoma 74 MCF 74 prostate cancer 70 asthma 70 myocardial infarction 68 osteoporosis 65 pulmonary fibrosis 63 osteosarcoma 61 lung cancer 61 epidermolysis bullosa 60 cholera 59 emphysema 58 heart failure 57 colorectal cancer 55 arthropathy 54 glomerulonephritis 53 tumorigenesis 53 tuberculosis 52 EDC 52 PSS 49 sarcoma 49 sepsis 48 chondrosarcoma 48 colon cancer 47 chronic obstructive pulmonary disease 47 Goodpasture's syndrome 46 cardiovascular disease 46 sepsis 46 synovitis 45 Peyronie's disease 45 gastric cancer 40 Dupuytren's disease 40 nephritis 40 leukemia 40 HIV 39 pertussis 38 worms 38 liver disease 38 glomerulosclerosis 37 primary tumor 37 lung disease 36 Alzheimer's disease 36 glioma 36 lung carcinoma 36 renal disease 36 more...

Symptom pain 127 skin damage 47 functional recovery 46 anesthesia 39 erythema 34 tremor 30 agitation 27 thinning 25 collapse 22 starvation 19 hyperoxia 16 fatigue 16 weakness 14 back pain 14 respiratory distress 14 hypothermia 13 flushing 13 diarrhea 10 arthralgia 10 low back pain 10 seizures 9 angina 8 stigma 6 skin irritation 5 autodigestion 5 cachexia 5 analgesia 5 abdominal pain 5 cough 4 discomfort 4 polyuria 4 HSA 4 discomfort 4 Stiffness 3 dyspnea 3 swollen joints 3 knee pain 3 ataxia 3 dry eye 3 regurgitation 3 disturbed balance 3 overweight 3 photophobia 2 splenomegaly 2 bitter taste 2 Fluctuation 2 Central post-stroke pain 2 Tenderness 2 inanition 2 sciatica 2 dry skin 2 acidity 2 shoulder pain 2 distraction 2 hepatomegaly 2 headache 2 myalgia 2 POA 2 Scratch 2 cerebellar ataxia 2 muscle stiffness 2 Hudson 2 spasticity 2 rigors 2 spasm 2 stomach pain 1 tense 1 Procedural pain 1 musculoskeletal disability 1 Joint hypermobility 1 Decreased activity 1 neurological disability 1 DNA marker 1 acute stress 1 anorexia 1 Ill 1 loss of balance 1 Trembling 1 rundown 1 Anoxia 1 more...

Drug Dermatol 368 lysine 156 ABC 79 Gelatin 79 Gel 77 PTH 68 MAP 65 ascorbate 59 CaCl2 59 CaCl2 58 CaCl2 58 IFN-gamma 57 ROS 57 uPA 51 IL-2 49 Pronase 43 CSF 43 Indomethacin 41 balanced salt solution 38 Cardiovasc 37 vitamin E 32 Nephron 30 Angiotensin II 28 Asn 28 CTX 23 ETS 22 caffeine 22 MRC 21 Hyaluronidase 21 Hyaluronidase 21 Ethanol 21 CTX 20 Glucagon 20 CTX 20 Histamine 20 EE2 18 NADH 18 DNase I 18 Albumin 17 lactose 17 Aprotinin 17 ROC 17 Forskolin 17 Nephron 17 Doxycycline 16 Ringer's solution 16 Leaf 16 Retinoic acid 15 Mutagen 15 Monit 15 CDP 14 Hypaque 14 Hypaque 14 Fraction 14 Batimastat 13 Batimastat 13 Glutathione 12 citric acid 11 IL-11 10 Growth hormone 10 Dial 10 IL-1ra 10 Asthma 10 Growth hormone 10 Vitamin A 9 Fluorescein 9 Atropine 9 Metrizamide 9 Glycerol 9 Heme 9 CCL 9 Vitamin E 9 Phenytoin 8 Paraffin 8 NAG 8 Papain 8 Fructose 8 ICI 8 L-tyrosine 7 Ginseng 7 more...

Enzyme collagenase 18340 MMP-3 1389 trypsin 1166 elastase 588 mitogen-activated protein kinase 571 hyaluronidase 506 interstitial collagenase 462 MMP 452 hyaluronidase 446 matrix metalloproteinase 2 316 alkaline phosphatase 275 pepsin 249 ERK 241 matrix metalloproteinase 9 232 urokinase-type plasminogen activator 226 plasmin 214 peroxidase 201 chymotrypsin 178 DNase 177 protein kinase C 177 protein kinase 166 neutrophil collagenase 129 lactate dehydrogenase 116 papain 111 adenylate cyclase 108 thrombin 106 cathepsin G 102 catalase 97 superoxide dismutase 95 focal adhesion kinase 93 neutrophil elastase 90 MEK 89 caspase-3 88 chondroitinase 87 chondroitinase 86 luciferase 86 ATPase 85 reverse transcriptase 84 cathepsin B 84 acetylcholinesterase 74 tissue plasminogen activator 69 thermolysin 68 alanine aminotransferase 67 neuraminidase 66 aspartate aminotransferase 65 acid phosphatase 63 lysozyme 62 phospholipase C 61 lipase 59 cathepsin K 59 tyrosinase 56 phosphodiesterase 54 gamma-glutamyl transpeptidase 53 beta-glucuronidase 52 renin 50 prolyl hydroxylase 49 beta-galactosidase 49 cathepsin D 45 ACE 40 glutathione S-transferase 37 lysyl oxidase 36 RNase 36 kallikrein 36 RNase 35 chloramphenicol acetyltransferase 34 tryptase 33 TACE 32 CD10 32 phosphatidylinositol 3-kinase 32 phospholipase A2 32 RNA polymerase 32 glutathione peroxidase 31 deoxyribonuclease 31 glyceraldehyde-3-phosphate dehydrogenase 31 deoxyribonuclease 30 type III procollagen 30 lipoprotein lipase 28 xanthine oxidase 28 5'-nucleotidase 27 cathepsin L 26 more...

Compound Dec 1326 DNA 940 calcium 927 glucose 751 Clin 738 Collagenase 607 sodium 595 acetate 531 water 496 oxygen 486 Collagen 461 proline 453 sulfate 423 TNF 396 EDTA 373 EDTA 373 leucine 330 zinc 329 SDS 325 arginine 300 cAMP 277 Gly 268 serine 262 phosphate 259 cysteine 231 alanine 224 lysine 209 AMP 202 salt 183 PGE2 177 ATP 175 ethanol 173 urea 166 hyaluronic acid 165 nitric oxide 158 methionine 158 galactose 156 tyrosine 153 Insulin 145 potassium 139 hydrogen 135 NH2 134 PEG 134 retinoic acid 119 Phe 114 iron 112 MTT 111 bromide 110 PEG 98 nitrogen 96 HCl 96 CO2 95 GSH 94 GSH 94 ACTH 94 aldosterone 93 ammonium 93 DEAE 91 MDA 89 Cardiol 89 PGE 87 guanidine 85 glycerol 80 acetic acid 77 Trypsin 75 iodine 74 ASA 73 Asp 73 TCA 73 Ile 72 PMA 72 silver 71 PMA 68 threonine 66 His 64 aldehyde 63 CaCl2 59 H2O2 57 acrylamide 56 tryptophan 53 more...

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