Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.3 (collagenase)
 18,340 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
procollagen alpha 1(I) chain 10.8
ZNF510 10.8
TCEAL2 10.8
PRG-4 10.8
T-cluster binding protein 10.8
collagenase 10.7
MMP-1 10.7
MMP-8 10.2
Apoptotic peptidase activating factor 1 9.8
archaemetzincin-1 9.8
Endothelial collagen 9.8
RAN binding protein 9 9.8
MMP1 protein 9.4
MMP-3 9.4
MMP-13 9.2
WISP3 protein 9.2
MMP-19 9.2
stromelysin 9.1
MMP-25 9.1
AB collagen 9.0
tissue inhibitor of metalloproteinases 8.9
MMP-10 8.8
TKT protein 8.8
LMF2 8.8
AMZ1 8.8
Cas-interacting zinc finger protein 8.8
M12 family 8.8
collagen alpha 1(I) chain 8.8
PLGL 8.6
MMP-7 8.6
TIMP 8.6
MT2-MMP 8.6
TIMP-2 8.6
MMP8 8.5
collagenase-3 8.5
MMP-11 8.5
MMP-27 8.4
VI-3 8.4
type I collagen alpha 1 chain 8.4
Epithelial membrane protein 1 8.4
more...
Disease
Other myeloid leukemia 9.8
Dendritic keratitis 9.2
LACH 9.2
Photodamaged skin 8.8
Mycoplasma arthritis 8.8
Vitreous liquefaction 8.4
Tendon calcification 8.4
BCDP 8.4
Myocardial hemorrhage 7.8
Psoriatic plaque 7.6
OASF 7.6
Tumor embolus 7.6
Ehlers-Danlos syndrome type VII 7.4
Elastolysis 7.4
Milwaukee shoulder 7.4
Milwaukee shoulder 7.3
Biventricular hypertrophy 7.3
stage I renal cell carcinoma 7.3
Medullary nephrocalcinosis 7.3
Dupuytren 7.3
Canine cutaneous histiocytoma 7.2
Tendinopathy 7.1
Congenital cutis laxa 7.1
Dupuytren's disease 7.0
Lipodermatosclerosis 7.0
Yoshida Sarcoma 7.0
Plantar fibromatosis 7.0
Chronic iron overload 6.9
Pulmonary cavitation 6.9
Hereditary nephritis 6.9
chronic skin ulcer 6.8
Acute esophagitis 6.8
Achilles tendinitis 6.7
Invasive bladder cancer 6.7
osteoblastic osteosarcoma 6.6
Peyronie's disease 6.6
Goodpasture's syndrome 6.6
Amyloid arthropathy 6.5
demineralization of bone 6.4
Mammary adenocarcinoma 6.4
more...
Symptom
Hegar's sign 10.8
Goodell's sign 10.8
Central post-stroke pain 7.0
Quadriceps weakness 6.4
Procedural pain 6.2
Trembling 6.1
skin damage 5.8
musculoskeletal disability 5.2
autodigestion 4.8
disturbed balance 4.5
nerve pain 4.0
inanition 4.0
Joint hypermobility 3.8
Muscle soreness 3.6
scaly skin 3.3
swollen joints 3.3
Tenderness 3.2
Scratch 3.1
pedal edema 3.0
POA 2.7
functional recovery 2.6
Stepping 2.5
Fluctuation 2.5
hyperoxia 2.4
Stiffness 2.4
erythema 2.2
rigors 2.1
skin irritation 2.0
agitation 2.0
thinning 1.9
loss of balance 1.9
Spots 1.9
flushing 1.8
stomach pain 1.8
rundown 1.8
dry skin 1.8
Hudson 1.7
Decreased activity 1.7
Anoxia 1.7
muscle stiffness 1.5
more...
Drug
Tanomastat 10.8
Santyl 10.2
Trocade 9.8
Prinomastat 9.2
Asiasarum root 9.2
Potaba 8.6
Olaflur 8.2
Batimastat 7.9
Batimastat 7.9
Berberine sulfate 7.8
Indacrinone 7.4
Travase 7.3
Methacholine chloride 7.3
Trimegestone 7.2
Tolmetin sodium 7.0
Arundic acid 6.9
nonatetraenoic acid 6.9
Levophed 6.9
Tesaglitazar 6.9
Citrus unshiu peel 6.7
Marimastat 6.6
Ilomastat 6.5
Gly-Tyr-Gly 6.4
Plasmanate 6.4
Hyaluronidase 6.3
Gelatin 6.3
Hyaluronidase 6.2
Avasimibe 6.2
Chymopapain 6.2
DOXY 6.1
Gold sodium thiomalate 6.0
Dexamethasone sodium phosphate 6.0
Camostat mesilate 6.0
Hirudoid 6.0
Pronase 5.8
Sulfaphenazole 5.8
K201 5.7
Tiopronin 5.7
Pirprofen 5.7
Vibramycin 5.5
more...
Enzyme
collagenase 10.8
neutrophil collagenase 10.2
nucleoside N-ribosyltransferase 9.8
brachyurin 9.8
interstitial collagenase 9.7
MMP-3 9.5
collagenase 3 9.4
hypodermin C 8.9
chondroitin sulfate ABC endolyase 8.8
flavastacin 8.8
matrix metalloproteinase 10 8.4
hippurate hydrolase 8.2
aggrecanase-1 8.1
bacillolysin 8.0
keratan sulfate sulfotransferase 8.0
proteinase yscD 8.0
thermomycolase 8.0
macrophage elastase 7.9
matrix metalloproteinase 2 7.9
deuterolysin 7.8
stromelysin-3 7.7
MMP 7.5
matrix metalloproteinase 9 7.5
hyaluronidase 7.4
pepsin B 7.3
clostripain 7.2
hyaluronidase 7.1
atrolysin C 6.9
elastase 6.8
matrix metalloproteinase 14 6.6
cathepsin G 6.6
endo-alpha-N-acetylgalactosaminidase 6.6
pseudolysin 6.5
tail-specific protease 6.5
lysyl hydroxylase 6.5
chymopapain 6.4
acylcarnitine hydrolase 6.4
vibriolysin 6.4
chymopapain 6.3
type III procollagen 6.2
more...
Compound
F 2268 10.8
Collagenase 10.0
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
4-chloro-N-cyclohexylbenzamide 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
C15H26O 9.8
Z-Gly-Pro-Leu-Gly-Pro 9.5
Astringin 9.2
Aranciamycin 9.2
C15H26O 9.2
(+)-Syringaresinol 9.2
C15H26O 9.2
C15H26O 9.2
Absinthin 9.2
C14H11NO2 9.2
2,3,3-trichloroacrylamide 9.2
benzoyl isothiocyanate 8.9
C15H26O 8.8
C15H26O 8.8
alpha-Eudesmol 8.8
Neryl acetate 8.8
Himachalol 8.8
C6H12N2O 8.4
Globulol 8.4
Isosakuranetin 8.4
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol 8.4
C15H26O 8.4
C20H24O6 8.4
Picrotin 8.4
C15H26O 8.4
Azocoll 8.2
Vernolide 8.2
C15H26O2 8.2
Hinesol 8.0
Diphenyliodonium chloride 8.0
more...