Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.3 (collagenase)
 18,340 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collagenase 13438
collagen 4986
MMP-1 3359
matrix metalloproteinase 1731
MMP-9 1380
MMP-2 1293
Sep 1232
MMP-3 1030
Mol 924
insulin 874
EPA 851
MMP-8 737
type I collagen 721
metalloproteinase 705
MMP-13 622
stromelysin 562
cytokine 550
fibronectin 533
TIMP-2 496
IL-6 464
more...
Disease
tumor 1187
cancer 1141
osteoarthritis 519
rheumatoid arthritis 424
diabetes 380
arthritis 355
SDS 301
carcinoma 241
periodontitis 220
atherosclerosis 213
plaque 210
stroke 207
melanoma 202
metastases 196
breast cancer 187
liver fibrosis 145
cold 130
tumor growth 127
ischemia 123
tumor progression 123
more...
Symptom
pain 127
skin damage 47
functional recovery 46
anesthesia 39
erythema 34
tremor 30
agitation 27
thinning 25
collapse 22
starvation 19
fatigue 16
hyperoxia 16
respiratory distress 14
back pain 14
weakness 14
flushing 13
hypothermia 13
diarrhea 10
low back pain 10
arthralgia 10
more...
Drug
Dermatol 368
lysine 156
Gelatin 79
ABC 79
Gel 77
PTH 68
MAP 65
CaCl2 59
ascorbate 59
CaCl2 58
CaCl2 58
IFN-gamma 57
ROS 57
uPA 51
IL-2 49
CSF 43
Pronase 43
Indomethacin 41
balanced salt solution 38
Cardiovasc 37
more...
Enzyme
collagenase 18340
MMP-3 1389
trypsin 1166
elastase 588
mitogen-activated protein kinase 571
hyaluronidase 506
interstitial collagenase 462
MMP 452
hyaluronidase 446
matrix metalloproteinase 2 316
alkaline phosphatase 275
pepsin 249
ERK 241
matrix metalloproteinase 9 232
urokinase-type plasminogen activator 226
plasmin 214
peroxidase 201
chymotrypsin 178
protein kinase C 177
DNase 177
more...
Compound
Dec 1326
DNA 940
calcium 927
glucose 751
Clin 738
Collagenase 607
sodium 595
acetate 531
water 496
oxygen 486
Collagen 461
proline 453
sulfate 423
TNF 396
EDTA 373
EDTA 373
leucine 330
zinc 329
SDS 325
arginine 300
more...