Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.3 (
collagenase
)
18,340
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Identification, separation and purification of human islets from acinar cells following
collagenase
digestion of the pancreas remains a difficult problem. We have identified and characterized two monoclonal antibodies,
CBL3
and TT62, with specific binding activity to human islets but not acinar cells. The antigens these monoclonal antibodies recognize are lipid in nature and thus unaffected by
collagenase
digestion of the human pancreas. These properties allow isolated human islets to be identified by fluorescein isothiocyanate-labeled
CBL3
and TT62, making these monoclonal antibodies potentially useful reagents in islet identification and purification.
...
PMID:Characterization of monoclonal antibodies CBL3 and TT62 with differing antigenic determinants specific for isolated human islets. 244 3
