Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.27 (thermolysin)
 1,894 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
TLN 14.0
P24A 12.0
carboxypeptidase O 11.2
ovostatin 11.2
Thioesterase II 11.0
cytoskeletal alpha-actinin 11.0
DPP III 11.0
zinc metalloendopeptidase 10.9
BANP 10.8
50 AA 10.7
dipeptidyl peptidase III 10.5
PLGL 10.3
integrin-like protein 10.2
metalloendopeptidase 10.2
TLP 10.1
G1L 10.0
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 10.0
ECE-2 10.0
N-acetyltransferase 10 10.0
muCANP 9.9
Kallikrein-4 9.8
DPP3 9.8
AAMP 9.7
Tro 9.7
HU-2 9.6
KLF16 9.6
NDH II 9.6
MADB 9.6
SHAP 9.6
A2ML1 9.6
elastin precursor 9.6
P125 9.6
breast cancer 1, early onset 9.5
H3P 9.5
neurolysin 9.4
ITIH 9.4
NRDC 9.3
STMP 9.3
HU-1 9.2
crn 9.2
zinc metallopeptidase 9.2
P76 9.2
T2R4 9.2
telencephalin 9.2
HSDJ 9.1
HL-20 9.1
ribosomal protein L34 9.1
DRAK2 9.1
calpain-like protease 9.1
Carboxypeptidase A 9.0
Neutral endopeptidase 8.9
HSP1 8.9
peptide deformylase 8.9
Profilaggrin 8.8
C1S 8.8
PGI(2) synthase 8.8
PreP 8.8
ZMPSTE24 8.8
mCANP 8.8
seminalplasmin 8.6
Hath1 8.6
Complement protein 8.6
CBS protein 8.6
chymotrypsin 8.6
PRP-3 8.6
ribosomal protein L12 8.6
metalloprotease 8.6
P2' 8.5
leukotriene A4 hydrolase 8.5
ICAM-5 8.5
D-beta-hydroxybutyrate dehydrogenase 8.4
PZP 8.4
nidogen-2 8.4
type II integral membrane protein 8.4
sphingosine-1-phosphate lyase 8.4
LTA4H 8.4
MMP-20 8.3
inhibitor-3 8.3
Chymotrypsin 8.2
angiotensin I-converting enzyme 8.2
more...
Disease
HHH 7.7
GFD 7.6
HHP 7.5
Lederer 7.4
BDB 7.2
Carrion 6.8
Weaver 6.7
vCJD 6.5
MSF 6.2
leprechaunism 6.2
ocular herpes 5.9
MLS 5.8
NPS 5.6
Sutton 5.5
Sander 5.4
SCP 5.2
EVA 5.2
Tick-borne encephalitis 5.1
BSE 5.1
vibriosis 5.0
metastatic colon cancer 5.0
avian leukosis 5.0
progeria 5.0
MTC 4.9
HYP 4.8
PDP 4.7
spongiform encephalopathy 4.7
corneal dystrophy 4.6
Gerstmann 4.6
lymphogranuloma venereum 4.6
PNET 4.6
PKS 4.5
SDS 4.5
PLS 4.5
Goldstein 4.4
Neoplasms 4.4
NLS 4.4
Tag 4.4
NS2 4.3
PSP 4.2
leptospirosis 4.2
SCS 4.2
nephrogenic diabetes insipidus 4.2
scrapie 4.2
leeches 4.2
chondrodysplasia 4.0
LBD 4.0
premature aging 3.9
Condensation 3.9
methemoglobinemia 3.9
SRS 3.8
PCC 3.8
LTD 3.8
stomatitis 3.7
RCM 3.7
EPS 3.7
mole 3.6
Legionella 3.6
LDA 3.5
EPS 3.5
fibrosarcoma 3.5
fibroma 3.4
mole 3.4
EDC 3.3
tetanus 3.2
Gilbert 3.2
Dissociation 3.1
TAM 3.1
choriocarcinoma 3.0
anthrax 3.0
EDA 3.0
Creutzfeldt-Jakob disease 3.0
PDB 2.9
cholera 2.9
juvenile rheumatoid arthritis 2.8
Thymus 2.8
Thymus 2.8
Thymus 2.8
SAR 2.8
HSP 2.7
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Symptom
cardiovascular impairment 7.3
autodigestion 5.7
Catch 5.0
bitter taste 4.6
eds 4.0
skin damage 3.5
tense 3.0
agitation 1.5
collapse 0.8
analgesia 0.3
acidity 0.1
diarrhea -0.8
fatigue -1.6
anesthesia -2.7
pain -3.0
Drug
Tenatoprazole 11.0
Gly-Tyr-Gly 8.6
Myotrophin 8.6
Phosphoramidon 8.3
Violaxanthin 8.1
Papain 7.7
BoNT/A 7.3
Protamine sulfate 7.1
Pronase 7.0
Human Serum Albumin 6.8
Bromelain 6.6
Asn 6.2
PE2 6.2
Aprotinin 5.8
Fragment 5.7
TRM 5.5
Maltose 5.2
DFP 5.2
Cibacron Blue 5.1
MTC 5.1
Glutamic acid 5.0
LMWH 5.0
L-tyrosine 4.8
linolenate 4.8
uPA 4.6
Riboflavin 4.4
pyridoxal phosphate 4.3
Biopolymers 4.3
NaI 4.2
NaI 4.2
NaI 4.2
NaI 4.2
lysine 3.9
Hypaque 3.9
Glycerol 3.9
Hypaque 3.8
CaCl2 3.7
CaCl2 3.7
Fraction 3.7
Scopolamine 3.7
CaCl2 3.7
Gel 3.6
Meth 3.6
balanced salt solution 3.4
Triclosan 3.4
Gelatin 3.3
Bevacizumab 3.3
Dakar 3.0
NAG 3.0
NADH 2.6
PTH 2.3
PCP 2.2
Glucagon 2.2
DNase I 2.0
Adriamycin 1.9
Glutathione 1.6
FAD 1.6
NH3 1.3
lactose 1.0
Nephron 0.9
Ethanol 0.8
citric acid 0.8
CTX 0.7
Leaf 0.6
ascorbate 0.5
Nephron 0.5
MAP 0.1
caffeine -0.4
Dermatol -0.8
CSF -0.9
Cardiovasc -3.6
Enzyme
thermolysin 14.0
bacillolysin 13.0
H2-proteinase 12.7
peptide hormone inactivating endopeptidase 12.5
vibriolysin 12.5
thermomycolase 12.2
coccolysin 12.0
pseudolysin 11.8
caldolysin 11.5
EC 2.7.7.42 11.2
enkephalinase B 10.9
aureolysin 10.8
actinase E 10.6
serralysin 10.5
streptopain 10.5
hypodermin C 10.4
GGGT 10.3
astacin 10.1
alpha-lytic protease 9.8
endoproteinase Glu-C 9.8
adamalysin 9.8
endoproteinase Asp-N 9.6
carboxypeptidase A 9.6
endothiapepsin 9.5
thimet oligopeptidase 9.5
deuterolysin 9.5
neurolysin 9.5
bothropasin 9.3
peptide deformylase 9.1
hatching enzyme 9.0
clostripain 8.9
subtilisin 8.8
ficin 8.8
chymotrypsin 8.7
oligopeptidase B 8.6
fibrolase 8.6
prozyme 8.6
proteinase A 8.6
lysyl endopeptidase 8.4
tetanus neurotoxin 8.4
protochlorophyllide oxidoreductase 8.3
GP-I 8.2
aggrecanase-1 8.1
PepX 8.1
collagenase 3 8.1
VanX 8.0
N-acetylglucosamine deacetylase 8.0
papain 8.0
glutathione-insulin transhydrogenase 7.9
cytochrome b6/f complex 7.9
bromelain 7.8
carboxyl proteinase 7.8
leishmanolysin 7.8
LTA4 hydrolase 7.8
octopine dehydrogenase 7.8
rhodopsin kinase 7.8
chymosin 7.7
arylsulfate sulfotransferase 7.7
elastase 7.7
DD-carboxypeptidase 7.6
pepsin 7.6
clotting enzyme 7.6
proteinase K 7.6
proteinase A 7.5
KLK7 7.5
trypsin 7.5
CD10 7.5
lactose synthetase 7.5
neutrophil collagenase 7.5
FtsH protease 7.5
stem bromelain 7.3
bromelin 7.3
phosphofructokinase 1 7.2
cathepsin G 7.1
penicillopepsin 7.1
endothelin-converting enzyme 7.0
tripeptidase 7.0
acyl-CoA thioesterase 7.0
protocatechuate 3,4-dioxygenase 6.9
insulin-degrading enzyme 6.8
more...
Compound
vinyl hexanoate 12.5
2,4,6-trimethylbenzoic acid 11.5
2,4,6-trimethylbenzoic acid 11.5
Boc-Asn 11.0
2-methoxy-5-(2,3,4-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one 10.9
vinyl decanoate 10.6
2-Naphthylamine 10.5
S152 10.1
Thiorphan 9.9
4-diphosphocytidyl-2C-methyl-D-erythritol 9.6
Azocoll 9.5
I acid 9.3
EPNP 9.3
Actinonin 9.2
N-acetylphenylalanine 9.0
N-acetylphenylalanine 9.0
N-acetylalanine 8.9
9-cis-Retinoic acid 8.9
N-Glycolylneuraminic acid 8.8
dihydrosphingosine-1-phosphate 8.8
vinyl laurate 8.8
Tropolone 8.7
1,2-cyclohexanedione 8.6
Protochlorophyllide 8.5
2-methyl-2-butanol 8.5
Meclizine 8.5
2-methyl-2-butanol 8.4
Desmosine 8.3
Chymostatin 8.3
Phosphoramidon 8.3
N-acetylserine 8.3
Cyanogen bromide 8.2
N-acetylalanine 8.1
Violaxanthin 8.1
2-methyl-2-propanol 7.9
2-methyl-2-propanol 7.9
Cys-Gly 7.7
N'-methylnicotinamide 7.6
U-14 7.5
4-oxobutanoic acid 7.4
Sodium deoxycholate 7.4
Cystine 7.3
dimethyl malonate 7.3
L-leucine 7.1
Phosphoserine 7.1
Z-Gly 7.1
trimethyllysine 7.0
S 1 7.0
Trypsin 7.0
Pro-Gly 6.9
Rhodopsin 6.9
butyramide 6.9
Collagenase 6.9
benzenesulfonyl fluoride 6.8
1,6-hexanediamine 6.8
Cystine 6.6
Dansyl 6.5
SC-1 6.5
SC-1 6.4
Protamine 6.4
Aspartame 6.4
Silver, 6.3
Amide 6.3
Sarcosine 6.2
Gly 6.2
Parthenolide 6.2
Ile 6.1
UDP-galactose 6.1
Phe 6.0
Chloral hydrate 6.0
D-Serine 5.9
mercaptoacetic acid 5.9
Deoxycholic acid 5.9
2-butanol 5.9
MAD 5.9
HMM 5.9
Polypeptide 5.9
Cystathionine 5.9
Cystathionine 5.9
4-vinylpyridine 5.8
more...