Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.27 (thermolysin)
1,894 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chymotrypsin 230
polypeptide 170
Sep 115
metalloprotease 109
Mol 99
SDS 68
collagenase 64
metalloproteinase 62
fibronectin 57
Pseudomonas 54
neutral endopeptidase 52
collagen 52
thrombin 44
glycoprotein 44
mast cell 44
metalloendopeptidase 42
Met 40
casein 38
peptidase 37
NMR 37
ATP 34
lysozyme 29
insulin 28
membrane-bound 26
elastin 24
rhodopsin 24
Trypsin 24
TLN 23
serine protease 23
dimeric 22
threonine 21
trypsin inhibitor 20
aminopeptidase 19
hinge 19
ATPase 18
heavy chain 18
bradykinin 17
membrane protein 17
Angiotensin-converting enzyme 17
angiotensin I-converting enzyme 16
fused 15
urokinase-type plasminogen activator 15
ADP 15
neuraminidase 14
renin 14
transferrin 13
alanyl 13
ribonuclease A 13
ACE 13
protease inhibitor 13
aminopeptidase N 12
P2' 12
Ang II 12
kallikrein 12
Chymotrypsin 12
TOF 12
lectin 11
serum albumin 11
alkaline phosphatase 11
fibrinogen 11
GTP 11
stromelysin 11
substance P 10
transglutaminase 10
C18 10
angiotensin II 10
NEP 10
C-terminal peptide 10
alpha-amylase 10
integral membrane protein 10
alpha-actinin 9
epidermal growth factor 9
Chlamydomonas 9
cathepsin G 9
peptide deformylase 9
metallopeptidase 9
myoglobin 9
microsomal 8
NADH 8
plasminogen 8
more...
Disease
SDS 68
tumor 20
hypertension 15
cancer 15
mole 13
mole 13
cholera 9
influenza 8
tetanus 7
cold 7
stomatitis 7
arthritis 6
multiple myeloma 6
neuroblastoma 6
Legionella 5
pheochromocytoma 5
PCC 5
Weaver 5
carcinoma 5
West 5
fibrosarcoma 5
atherosclerosis 5
sarcoma 5
spongiform encephalopathy 4
leptospirosis 4
leukemia 4
scrapie 4
melanoma 4
PLS 4
congestive heart failure 3
sepsis 3
gastroenteritis 3
heart failure 3
pertussis 3
Proteus 3
SAR 3
colon cancer 3
dehydration 3
PDB 3
osteoarthritis 2
HIV 2
fibroma 2
Barrett's esophagus 2
diabetes 2
type 2 diabetes 2
MLS 2
infectious diseases 2
immunodeficiency 2
avian leukosis 2
fits 2
nephrotic syndrome 2
NPS 2
rheumatoid arthritis 2
BSE 2
SCH 2
Still 2
choriocarcinoma 2
plaque 2
anthrax 2
Creutzfeldt-Jakob disease 2
progeria 2
abdominal aortic aneurysm 2
Dissociation 2
glioblastoma 2
GSH 2
malaria 2
diphtheria 2
Tag 2
cardiovascular disease 2
premature aging 2
cornea 2
polyneuropathy 1
hypothyroidism 1
EDA 1
PDP 1
NLS 1
type 1 diabetes 1
vCJD 1
RCM 1
tuberculosis 1
more...
Symptom
collapse 3
agitation 2
bitter taste 2
diarrhea 2
analgesia 2
pain 2
fatigue 1
autodigestion 1
tense 1
skin damage 1
Catch 1
anesthesia 1
cardiovascular impairment 1
acidity 1
eds 1
Drug
Asn 53
lysine 53
Gel 11
Biopolymers 10
Pronase 10
Dermatol 9
NADH 8
BoNT/A 8
Fragment 7
Papain 7
CaCl2 5
CaCl2 5
CaCl2 5
Phosphoramidon 4
L-tyrosine 4
Aprotinin 3
uPA 3
pyridoxal phosphate 3
NaI 2
DNase I 2
DFP 2
lactose 2
ascorbate 2
Leaf 2
NaI 2
NaI 2
NaI 2
Nephron 2
Fraction 2
PTH 2
Glycerol 2
Bromelain 1
TRM 1
caffeine 1
Maltose 1
Myotrophin 1
balanced salt solution 1
MTC 1
Tenatoprazole 1
Glutathione 1
LMWH 1
citric acid 1
Dakar 1
Cibacron Blue 1
Glucagon 1
Glutamic acid 1
Riboflavin 1
Human Serum Albumin 1
Hypaque 1
Cardiovasc 1
NH3 1
linolenate 1
Gelatin 1
PCP 1
MAP 1
Hypaque 1
Protamine sulfate 1
Triclosan 1
Adriamycin 1
CSF 1
NAG 1
Meth 1
Bevacizumab 1
CTX 1
PE2 1
Ethanol 1
FAD 1
Nephron 1
Scopolamine 1
Gly-Tyr-Gly 1
Violaxanthin 1
Enzyme
thermolysin 1894
trypsin 463
chymotrypsin 276
subtilisin 118
elastase 109
CD10 105
pepsin 100
papain 97
collagenase 68
ACE 54
proteinase K 46
carboxypeptidase A 44
thrombin 44
lysozyme 29
plasmin 24
endoproteinase Glu-C 22
RNase 20
ATPase 20
CD13 19
protein kinase 19
kallikrein 19
MMP-3 16
astacin 16
pseudolysin 16
urokinase-type plasminogen activator 15
neuraminidase 15
proteasome 15
cathepsin G 15
bromelain 14
renin 14
ERK 14
RNase 13
peroxidase 12
ribonuclease 11
alkaline phosphatase 11
ribonuclease 11
phosphorylase 10
bacillolysin 10
alpha-amylase 10
transglutaminase 10
neutrophil elastase 10
phospholipase A2 10
lysyl endopeptidase 10
thromboplastin 9
botulinum neurotoxin 9
thimet oligopeptidase 9
ficin 9
RNA polymerase 8
peptide deformylase 8
lipase 8
clostripain 7
superoxide dismutase 7
ACS 7
endoproteinase Asp-N 7
cathepsin D 7
phospholipase C 7
leucine aminopeptidase 7
AMPK 7
vibriolysin 7
carboxypeptidase Y 7
serralysin 6
proteinase A 6
lactate dehydrogenase 6
phosphodiesterase 6
carbonic anhydrase 6
glutathione S-transferase 6
caspase-1 6
chymosin 6
mitogen-activated protein kinase 6
Pla 6
protochlorophyllide oxidoreductase 6
alcohol dehydrogenase 6
alpha-lytic protease 6
deaminase 6
insulin-degrading enzyme 5
dihydrofolate reductase 5
aureolysin 5
cathepsin B 5
rhodopsin kinase 5
protein kinase C 5
more...
Compound
zinc 274
Phe 190
leucine 183
alanine 178
Dec 163
Gly 149
arginine 136
water 127
lysine 126
tyrosine 117
Asp 114
serine 111
NH2 109
calcium 105
His 100
cysteine 97
sodium 90
Ile 88
methionine 85
bromide 81
sulfate 75
threonine 75
SDS 72
hydrogen 65
tryptophan 54
tryptophan 52
tryptophan 51
tryptophan 51
EDTA 49
DNA 49
EDTA 49
urea 41
salt 40
phosphate 39
ATP 34
proline 33
glutamic acid 32
guanidine 30
acetate 30
ethanol 26
cobalt 25
oxygen 25
ammonium 24
Trypsin 24
glutamate 24
galactose 23
valine 22
aspartic acid 21
L-leucine 20
DEAE 19
ADP 18
ethyl acetate 17
glucose 16
glycerol 16
aspartic acid 16
HCl 16
methanol 15
nitrogen 15
iron 15
ADP 15
ADP 15
glutamine 15
aspartic acid 14
copper 14
aspartic acid 14
asparagine 14
isoleucine 13
Mg2+ 12
TOF 12
isoleucine 12
acetic acid 12
Triton X-100 12
GTP 11
hydroxylamine 11
manganese 11
hydroxylamine 11
isopropanol 10
acetone 10
COS 10
phosphorus 10
more...