Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.27 (
thermolysin
)
1,894
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
chymotrypsin
230
polypeptide
170
Sep
115
metalloprotease
109
Mol
99
SDS
68
collagenase
64
metalloproteinase
62
fibronectin
57
Pseudomonas
54
collagen
52
neutral endopeptidase
52
thrombin
44
glycoprotein
44
mast cell
44
metalloendopeptidase
42
Met
40
casein
38
NMR
37
peptidase
37
ATP
34
lysozyme
29
insulin
28
membrane-bound
26
rhodopsin
24
Trypsin
24
elastin
24
serine protease
23
TLN
23
dimeric
22
threonine
21
trypsin inhibitor
20
aminopeptidase
19
hinge
19
heavy chain
18
ATPase
18
membrane protein
17
Angiotensin-converting enzyme
17
bradykinin
17
angiotensin I-converting enzyme
16
more...
Disease
SDS
68
tumor
20
cancer
15
hypertension
15
mole
13
mole
13
cholera
9
influenza
8
tetanus
7
cold
7
stomatitis
7
arthritis
6
multiple myeloma
6
neuroblastoma
6
West
5
PCC
5
carcinoma
5
Weaver
5
fibrosarcoma
5
atherosclerosis
5
Legionella
5
pheochromocytoma
5
sarcoma
5
leukemia
4
leptospirosis
4
melanoma
4
spongiform encephalopathy
4
PLS
4
scrapie
4
colon cancer
3
dehydration
3
SAR
3
gastroenteritis
3
congestive heart failure
3
heart failure
3
sepsis
3
PDB
3
pertussis
3
Proteus
3
HIV
2
more...
Symptom
collapse
3
agitation
2
bitter taste
2
diarrhea
2
analgesia
2
pain
2
fatigue
1
autodigestion
1
tense
1
skin damage
1
Catch
1
anesthesia
1
cardiovascular impairment
1
acidity
1
eds
1
Drug
lysine
53
Asn
53
Gel
11
Biopolymers
10
Pronase
10
Dermatol
9
NADH
8
BoNT/A
8
Fragment
7
Papain
7
CaCl2
5
CaCl2
5
CaCl2
5
L-tyrosine
4
Phosphoramidon
4
uPA
3
pyridoxal phosphate
3
Aprotinin
3
Glycerol
2
PTH
2
NaI
2
Fraction
2
ascorbate
2
Nephron
2
Leaf
2
NaI
2
DFP
2
NaI
2
NaI
2
lactose
2
DNase I
2
Adriamycin
1
NAG
1
TRM
1
Bevacizumab
1
Myotrophin
1
balanced salt solution
1
Tenatoprazole
1
Glutathione
1
LMWH
1
more...
Enzyme
thermolysin
1894
trypsin
463
chymotrypsin
276
subtilisin
118
elastase
109
CD10
105
pepsin
100
papain
97
collagenase
68
ACE
54
proteinase K
46
carboxypeptidase A
44
thrombin
44
lysozyme
29
plasmin
24
endoproteinase Glu-C
22
RNase
20
ATPase
20
kallikrein
19
protein kinase
19
CD13
19
MMP-3
16
astacin
16
pseudolysin
16
urokinase-type plasminogen activator
15
neuraminidase
15
cathepsin G
15
proteasome
15
renin
14
ERK
14
bromelain
14
RNase
13
peroxidase
12
alkaline phosphatase
11
ribonuclease
11
ribonuclease
11
bacillolysin
10
neutrophil elastase
10
transglutaminase
10
lysyl endopeptidase
10
more...
Compound
zinc
274
Phe
190
leucine
183
alanine
178
Dec
163
Gly
149
arginine
136
water
127
lysine
126
tyrosine
117
Asp
114
serine
111
NH2
109
calcium
105
His
100
cysteine
97
sodium
90
Ile
88
methionine
85
bromide
81
threonine
75
sulfate
75
SDS
72
hydrogen
65
tryptophan
54
tryptophan
52
tryptophan
51
tryptophan
51
EDTA
49
DNA
49
EDTA
49
urea
41
salt
40
phosphate
39
ATP
34
proline
33
glutamic acid
32
guanidine
30
acetate
30
ethanol
26
more...