Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.27 (thermolysin)
 1,894 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
TLN 14.0
P24A 12.0
carboxypeptidase O 11.2
ovostatin 11.2
cytoskeletal alpha-actinin 11.0
Thioesterase II 11.0
DPP III 11.0
zinc metalloendopeptidase 10.9
BANP 10.8
50 AA 10.7
dipeptidyl peptidase III 10.5
PLGL 10.3
integrin-like protein 10.2
metalloendopeptidase 10.2
TLP 10.1
G1L 10.0
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 10.0
ECE-2 10.0
N-acetyltransferase 10 10.0
muCANP 9.9
DPP3 9.8
Kallikrein-4 9.8
AAMP 9.7
Tro 9.7
NDH II 9.6
HU-2 9.6
MADB 9.6
KLF16 9.6
SHAP 9.6
A2ML1 9.6
P125 9.6
elastin precursor 9.6
breast cancer 1, early onset 9.5
H3P 9.5
neurolysin 9.4
ITIH 9.4
NRDC 9.3
STMP 9.3
HU-1 9.2
crn 9.2
zinc metallopeptidase 9.2
T2R4 9.2
P76 9.2
telencephalin 9.2
DRAK2 9.1
HL-20 9.1
ribosomal protein L34 9.1
HSDJ 9.1
calpain-like protease 9.1
Carboxypeptidase A 9.0
Neutral endopeptidase 8.9
HSP1 8.9
peptide deformylase 8.9
PreP 8.8
Profilaggrin 8.8
PGI(2) synthase 8.8
C1S 8.8
ZMPSTE24 8.8
mCANP 8.8
seminalplasmin 8.6
Hath1 8.6
CBS protein 8.6
Complement protein 8.6
chymotrypsin 8.6
ribosomal protein L12 8.6
PRP-3 8.6
metalloprotease 8.6
P2' 8.5
leukotriene A4 hydrolase 8.5
ICAM-5 8.5
nidogen-2 8.4
D-beta-hydroxybutyrate dehydrogenase 8.4
PZP 8.4
LTA4H 8.4
type II integral membrane protein 8.4
sphingosine-1-phosphate lyase 8.4
inhibitor-3 8.3
MMP-20 8.3
Chymotrypsin 8.2
angiotensin I-converting enzyme 8.2
phosphofructokinase 1 8.2
P54 8.2
insulinase 8.1
PRR1 8.1
NEP 8.1
Angiotensin I converting enzyme 8.1
kallikrein 7 8.1
pregnancy zone protein 8.1
TRH-degrading ectoenzyme 8.1
RAP1A 8.1
rhodopsin kinase 8.1
smooth muscle myosin light chain kinase 8.1
A2M 8.1
GPA2 8.0
neutral endopeptidase 8.0
aggrecanase-1 8.0
NUDT15 8.0
RKIP 7.9
IgSF 7.9
phosphodiesterase 5A 7.9
acid DNase 7.8
nuclear transporter 7.8
SUP 7.8
A-9 7.7
stratum corneum chymotryptic enzyme 7.7
D53 7.7
V lambda 7.7
immunoglobulin lambda light chain 7.6
LMN 7.6
retinoic acid receptor gamma 7.6
melanotransferrin 7.5
Type VII collagen 7.5
P51 7.5
ECE-1 7.5
HHH 7.5
Neuropathy target esterase 7.5
FSAP 7.5
Apo(a) 7.4
CPTI 7.4
FAS1 7.4
p74 7.4
Rpn11 7.4
alpha polypeptide 7.4
urogastrone 7.4
MLCK 7.4
Carboxypeptidase Y 7.4
JAB1 7.4
metallopeptidase 7.4
transition protein 1 7.4
FA1 7.3
aminopeptidase N 7.3
POR 7.3
pancreatic stone protein 7.2
LAMA 7.2
inter-alpha-trypsin inhibitor 7.2
CHRM2 7.2
cathepsin B1 7.2
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 7.2
CCP1 7.2
MPR 46 7.2
palmitoyl-CoA hydrolase 7.1
metalloproteinase 7.1
endoprotease 7.1
ZFP 7.1
glutathione-insulin transhydrogenase 7.1
NTF2 7.1
beta polypeptide 7.1
carbonic anhydrase B 7.1
angiotensin I converting enzyme 7.0
EFA6 7.0
protamine 2 7.0
DS1 7.0
D-amino-acid oxidase 7.0
pancreatitis-associated protein 7.0
CT-1 7.0
CCP2 7.0
neurosin 7.0
PPL 7.0
Trypsin 7.0
80 kDa) 7.0
more...
Disease
HHH 7.7
GFD 7.6
HHP 7.5
Lederer 7.4
BDB 7.2
Carrion 6.8
Weaver 6.7
vCJD 6.5
MSF 6.2
leprechaunism 6.2
ocular herpes 5.9
MLS 5.8
NPS 5.6
Sutton 5.5
Sander 5.4
SCP 5.2
EVA 5.2
Tick-borne encephalitis 5.1
BSE 5.1
vibriosis 5.0
metastatic colon cancer 5.0
avian leukosis 5.0
progeria 5.0
MTC 4.9
HYP 4.8
PDP 4.7
spongiform encephalopathy 4.7
corneal dystrophy 4.6
Gerstmann 4.6
lymphogranuloma venereum 4.6
PNET 4.6
PKS 4.5
SDS 4.5
PLS 4.5
Goldstein 4.4
Neoplasms 4.4
NLS 4.4
Tag 4.4
NS2 4.3
PSP 4.2
leptospirosis 4.2
SCS 4.2
nephrogenic diabetes insipidus 4.2
scrapie 4.2
leeches 4.2
chondrodysplasia 4.0
LBD 4.0
premature aging 3.9
Condensation 3.9
methemoglobinemia 3.9
SRS 3.8
PCC 3.8
LTD 3.8
stomatitis 3.7
RCM 3.7
EPS 3.7
mole 3.6
Legionella 3.6
LDA 3.5
EPS 3.5
fibrosarcoma 3.5
fibroma 3.4
mole 3.4
EDC 3.3
tetanus 3.2
Gilbert 3.2
Dissociation 3.1
TAM 3.1
choriocarcinoma 3.0
anthrax 3.0
EDA 3.0
Creutzfeldt-Jakob disease 3.0
PDB 2.9
cholera 2.9
juvenile rheumatoid arthritis 2.8
Thymus 2.8
Thymus 2.8
Thymus 2.8
SAR 2.8
HSP 2.7
SCH 2.7
hairy cell leukemia 2.7
Barrett's esophagus 2.6
Proteus 2.6
TOC 2.6
EIA 2.6
pheochromocytoma 2.5
tularemia 2.5
PAF 2.5
Rous sarcoma 2.5
AAA 2.5
membranous nephropathy 2.4
Brucella abortus 2.4
tic 2.4
giant cell arteritis 2.4
pemphigoid 2.4
smallpox 2.3
progressive supranuclear palsy 2.3
medullary thyroid carcinoma 2.3
hemorrhagic fever 2.3
warts 2.2
diphtheria 2.2
gastroenteritis 2.1
transitional cell carcinoma 2.1
myeloid leukemia 2.1
aqueous humor 2.1
DM1 2.0
abdominal aortic aneurysm 2.0
hepatic encephalopathy 2.0
Still 1.9
neuroblastoma 1.9
PCA 1.8
nephrotic syndrome 1.7
Shiga 1.7
respiratory infection 1.7
sarcoma 1.7
dyskinesia 1.7
zoonosis 1.6
multiple myeloma 1.5
Bordetella 1.5
IVF 1.4
pertussis 1.4
PCP 1.3
pulmonary fibrosis 1.3
Pancreas 1.3
macular degeneration 1.2
Lyme disease 1.2
influenza 1.2
Pancreas 1.2
hemolytic anemia 1.2
Duchenne muscular dystrophy 1.1
aspergillosis 1.1
polyneuropathy 1.1
dehydration 1.1
congestive heart failure 1.1
anaphylaxis 1.1
candidiasis 1.0
Cryptococcus neoformans 1.0
Blocking 0.9
glioblastoma 0.9
colon cancer 0.8
APC 0.7
acute pancreatitis 0.7
vaccinia 0.7
Syndrome 0.7
diabetic nephropathy 0.6
NHS 0.6
retinoblastoma 0.6
ventricular hypertrophy 0.6
hypertension 0.6
arthritis 0.5
myopathy 0.5
cornea 0.5
amyloidosis 0.5
Brown 0.4
Chlamydia 0.4
encephalomyelitis 0.4
cold 0.4
sarcoidosis 0.3
Huntington's disease 0.3
more...
Symptom
cardiovascular impairment 7.3
autodigestion 5.7
Catch 5.0
bitter taste 4.6
eds 4.0
skin damage 3.5
tense 3.0
agitation 1.5
collapse 0.8
analgesia 0.3
acidity 0.1
diarrhea -0.8
fatigue -1.6
anesthesia -2.7
pain -3.0
Drug
Tenatoprazole 11.0
Gly-Tyr-Gly 8.6
Myotrophin 8.6
Phosphoramidon 8.3
Violaxanthin 8.1
Papain 7.7
BoNT/A 7.3
Protamine sulfate 7.1
Pronase 7.0
Human Serum Albumin 6.8
Bromelain 6.6
Asn 6.2
PE2 6.2
Aprotinin 5.8
Fragment 5.7
TRM 5.5
Maltose 5.2
DFP 5.2
Cibacron Blue 5.1
MTC 5.1
Glutamic acid 5.0
LMWH 5.0
L-tyrosine 4.8
linolenate 4.8
uPA 4.6
Riboflavin 4.4
pyridoxal phosphate 4.3
Biopolymers 4.3
NaI 4.2
NaI 4.2
NaI 4.2
NaI 4.2
lysine 3.9
Hypaque 3.9
Glycerol 3.9
Hypaque 3.8
CaCl2 3.7
CaCl2 3.7
Fraction 3.7
Scopolamine 3.7
CaCl2 3.7
Gel 3.6
Meth 3.6
balanced salt solution 3.4
Triclosan 3.4
Gelatin 3.3
Bevacizumab 3.3
Dakar 3.0
NAG 3.0
NADH 2.6
PTH 2.3
PCP 2.2
Glucagon 2.2
DNase I 2.0
Adriamycin 1.9
Glutathione 1.6
FAD 1.6
NH3 1.3
lactose 1.0
Nephron 0.9
Ethanol 0.8
citric acid 0.8
CTX 0.7
Leaf 0.6
ascorbate 0.5
Nephron 0.5
MAP 0.1
caffeine -0.4
Dermatol -0.8
CSF -0.9
Cardiovasc -3.6
Enzyme
thermolysin 14.0
bacillolysin 13.0
H2-proteinase 12.7
vibriolysin 12.5
peptide hormone inactivating endopeptidase 12.5
thermomycolase 12.2
coccolysin 12.0
pseudolysin 11.8
caldolysin 11.5
EC 2.7.7.42 11.2
enkephalinase B 10.9
aureolysin 10.8
actinase E 10.6
serralysin 10.5
streptopain 10.5
hypodermin C 10.4
GGGT 10.3
astacin 10.1
alpha-lytic protease 9.8
endoproteinase Glu-C 9.8
adamalysin 9.8
endoproteinase Asp-N 9.6
carboxypeptidase A 9.6
endothiapepsin 9.5
thimet oligopeptidase 9.5
deuterolysin 9.5
neurolysin 9.5
bothropasin 9.3
peptide deformylase 9.1
hatching enzyme 9.0
clostripain 8.9
subtilisin 8.8
ficin 8.8
chymotrypsin 8.7
oligopeptidase B 8.6
fibrolase 8.6
prozyme 8.6
proteinase A 8.6
lysyl endopeptidase 8.4
tetanus neurotoxin 8.4
protochlorophyllide oxidoreductase 8.3
GP-I 8.2
aggrecanase-1 8.1
PepX 8.1
collagenase 3 8.1
VanX 8.0
N-acetylglucosamine deacetylase 8.0
papain 8.0
glutathione-insulin transhydrogenase 7.9
cytochrome b6/f complex 7.9
bromelain 7.8
leishmanolysin 7.8
carboxyl proteinase 7.8
LTA4 hydrolase 7.8
rhodopsin kinase 7.8
octopine dehydrogenase 7.8
chymosin 7.7
arylsulfate sulfotransferase 7.7
elastase 7.7
DD-carboxypeptidase 7.6
pepsin 7.6
clotting enzyme 7.6
proteinase K 7.6
proteinase A 7.5
KLK7 7.5
trypsin 7.5
CD10 7.5
lactose synthetase 7.5
neutrophil collagenase 7.5
FtsH protease 7.5
stem bromelain 7.3
bromelin 7.3
phosphofructokinase 1 7.2
cathepsin G 7.1
penicillopepsin 7.1
endothelin-converting enzyme 7.0
tripeptidase 7.0
acyl-CoA thioesterase 7.0
protocatechuate 3,4-dioxygenase 6.9
insulin-degrading enzyme 6.8
SLB 6.8
Pla 6.8
prolyl endopeptidase 6.7
endo-beta-galactosidase 6.7
pyroglutamate aminopeptidase 6.7
3-isopropylmalate dehydrogenase 6.6
fructose-2,6-bisphosphatase 6.5
carboxypeptidase Y 6.5
CD13 6.5
cathepsin C 6.4
xylose isomerase 6.4
chymopapain 6.4
carboxypeptidase B 6.4
starch synthase 6.3
PST 6.3
aminopeptidase A 6.3
botulinum neurotoxin 6.3
phosphatidate phosphatase 6.3
MMP-3 6.3
chymopapain 6.3
aminopeptidase B 6.3
PTR 6.3
haloalkane dehalogenase 6.2
acylphosphatase 6.2
leucine aminopeptidase 6.2
AP lyase 6.2
PPH 6.1
DD-carboxypeptidase 6.1
endo-beta-galactosidase 6.1
pyruvate oxidase 6.0
IgA1 protease 6.0
collagenase 6.0
pyruvate oxidase 6.0
methylamine dehydrogenase 6.0
meprin 5.9
dihydroorotase 5.9
chondroitinase AC 5.8
interstitial collagenase 5.7
kallikrein 5.7
granule-bound starch synthase 5.7
calcium pump 5.6
ACE 5.6
acrosin 5.6
cytochrome c peroxidase 5.6
transhydrogenase 5.6
guanylate kinase 5.5
fructokinase 5.5
cathepsin H 5.5
alanine aminopeptidase 5.5
glycerol kinase 5.5
plasmin 5.5
beta-hydroxybutyrate dehydrogenase 5.5
prostacyclin synthase 5.5
legumain 5.4
neutrophil elastase 5.4
HCS 5.4
halogenase 5.3
NAD glycohydrolase 5.3
cruzipain 5.3
DNase II 5.3
phosphorylase kinase 5.2
SCP 5.2
Rex 5.2
PGM 5.2
cGMP phosphodiesterase 5.1
transglutaminase 5.1
ADP-ribosyltransferase 5.0
Hageman factor 5.0
alpha-amylase 5.0
ADP-ribosyltransferase 5.0
phosphorylase 4.9
cytochrome P-450scc 4.9
isopeptidase 4.9
serine hydroxymethyltransferase 4.8
cathepsin D 4.8
adrenodoxin reductase 4.8
ribonuclease 4.8
ribonuclease 4.8
phenylethanolamine N-methyltransferase 4.8
tissue kallikrein 4.7
more...
Compound
vinyl hexanoate 12.5
2,4,6-trimethylbenzoic acid 11.5
2,4,6-trimethylbenzoic acid 11.5
Boc-Asn 11.0
2-methoxy-5-(2,3,4-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one 10.9
vinyl decanoate 10.6
2-Naphthylamine 10.5
S152 10.1
Thiorphan 9.9
4-diphosphocytidyl-2C-methyl-D-erythritol 9.6
Azocoll 9.5
I acid 9.3
EPNP 9.3
Actinonin 9.2
N-acetylphenylalanine 9.0
N-acetylphenylalanine 9.0
9-cis-Retinoic acid 8.9
N-acetylalanine 8.9
N-Glycolylneuraminic acid 8.8
dihydrosphingosine-1-phosphate 8.8
vinyl laurate 8.8
Tropolone 8.7
1,2-cyclohexanedione 8.6
Protochlorophyllide 8.5
2-methyl-2-butanol 8.5
Meclizine 8.5
2-methyl-2-butanol 8.4
Desmosine 8.3
Chymostatin 8.3
Phosphoramidon 8.3
N-acetylserine 8.3
Cyanogen bromide 8.2
Violaxanthin 8.1
N-acetylalanine 8.1
2-methyl-2-propanol 7.9
2-methyl-2-propanol 7.9
Cys-Gly 7.7
N'-methylnicotinamide 7.6
U-14 7.5
4-oxobutanoic acid 7.4
Sodium deoxycholate 7.4
Cystine 7.3
dimethyl malonate 7.3
L-leucine 7.1
Phosphoserine 7.1
Z-Gly 7.1
trimethyllysine 7.0
S 1 7.0
Trypsin 7.0
Pro-Gly 6.9
Rhodopsin 6.9
butyramide 6.9
Collagenase 6.9
benzenesulfonyl fluoride 6.8
1,6-hexanediamine 6.8
Cystine 6.6
Dansyl 6.5
SC-1 6.5
SC-1 6.4
Protamine 6.4
Aspartame 6.4
Silver, 6.3
Amide 6.3
Sarcosine 6.2
Gly 6.2
Parthenolide 6.2
Ile 6.1
UDP-galactose 6.1
Phe 6.0
Chloral hydrate 6.0
D-Serine 5.9
mercaptoacetic acid 5.9
Deoxycholic acid 5.9
2-butanol 5.9
MAD 5.9
HMM 5.9
Polypeptide 5.9
Cystathionine 5.9
Cystathionine 5.9
4-vinylpyridine 5.8
PH2 5.8
Bacitracin 5.8
guanidine 5.8
2-phosphoglycerate 5.8
Elastin 5.8
Asp 5.8
sulfamide 5.8
sulfamide 5.8
TME 5.8
Diacetyl 5.7
zinc 5.7
3-(dimethylamino)propyl 5.7
leucine 5.7
ADMA 5.6
Dithiothreitol 5.6
trifluoromethanesulfonic acid 5.6
M 2 5.6
PMSF 5.6
1-pentanol 5.6
trifluoromethanesulfonic acid 5.5
TPCK 5.5
HFIP 5.5
mercaptoacetic acid 5.5
TFE 5.5
MCE 5.4
K19 5.4
alanine 5.4
Dithiothreitol 5.4
PHE 5.4
keratan sulfate 5.3
NH4OH 5.3
NH2 5.3
fructose-6-P 5.2
IBA 5.2
His-Leu 5.2
E-64 5.2
1-propanol 5.2
Maltose 5.2
PDP 5.1
hydroxylamine 5.1
Keratin 5.1
2-propanol 5.1
2-propanol 5.1
D-Ala-D-Ala 5.1
hydroxylamine 5.0
glutamic acid 5.0
MTC 5.0
Valine 5.0
bromide 5.0
Cysteamine 5.0
B17 5.0
HBr 4.9
EDTA 4.9
EDTA 4.9
AF-2 4.9
N-hydroxysuccinimide ester 4.9
Glu-Glu 4.9
3-hydroxybutyric acid 4.9
11-cis-retinal 4.9
CMK 4.9
T13 4.9
threonine 4.8
serine 4.8
aspartic acid 4.8
CHAPS 4.8
lysine 4.7
MCP 4.7
8-Br-cGMP 4.7
Kallikrein 4.7
butyl acrylate 4.7
valine 4.7
tryptophan 4.6
tryptophan 4.6
Brilliant Blue 4.6
ETH 4.6
methionine 4.6
tryptophan 4.6
arginine 4.6
aspartic acid 4.5
Histidine 4.5
more...