Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.27 (thermolysin)
 1,894 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chymotrypsin 230
polypeptide 170
Sep 115
metalloprotease 109
Mol 99
SDS 68
collagenase 64
metalloproteinase 62
fibronectin 57
Pseudomonas 54
collagen 52
neutral endopeptidase 52
thrombin 44
mast cell 44
glycoprotein 44
metalloendopeptidase 42
Met 40
casein 38
NMR 37
peptidase 37
ATP 34
lysozyme 29
insulin 28
membrane-bound 26
elastin 24
Trypsin 24
rhodopsin 24
serine protease 23
TLN 23
dimeric 22
threonine 21
trypsin inhibitor 20
hinge 19
aminopeptidase 19
heavy chain 18
ATPase 18
bradykinin 17
Angiotensin-converting enzyme 17
membrane protein 17
angiotensin I-converting enzyme 16
urokinase-type plasminogen activator 15
ADP 15
fused 15
renin 14
neuraminidase 14
ribonuclease A 13
transferrin 13
ACE 13
protease inhibitor 13
alanyl 13
Ang II 12
kallikrein 12
aminopeptidase N 12
TOF 12
P2' 12
Chymotrypsin 12
serum albumin 11
stromelysin 11
lectin 11
fibrinogen 11
GTP 11
alkaline phosphatase 11
angiotensin II 10
alpha-amylase 10
transglutaminase 10
C18 10
NEP 10
substance P 10
C-terminal peptide 10
integral membrane protein 10
alpha-actinin 9
myoglobin 9
epidermal growth factor 9
Chlamydomonas 9
metallopeptidase 9
peptide deformylase 9
cathepsin G 9
esterase 8
plasminogen 8
TLP 8
matrix metalloproteinase 8
neutrophil elastase 8
microsomal 8
precursor protein 8
NADH 8
hemoglobin 8
DPP III 8
RNase A 8
MGC 7
glycogen phosphorylase 7
endoprotease 7
cytochrome 7
IgA 7
NADPH 7
thymus 7
SUP 7
Gen 7
factor Xa 7
Proteinase 7
albumin 7
CD13 7
NAD 7
cathepsin D 7
leucine aminopeptidase 7
myosin 7
MMP-3 7
phospholipase A2 7
beta-casein 7
ACS 7
thrombospondin 7
cytochrome c 7
prion 6
ALA 6
beta 1 6
phosphodiesterase 6
cAMP-dependent protein kinase 6
PEG 6
ESI 6
alcohol dehydrogenase 6
carbonic anhydrase 6
Neutral endopeptidase 6
dilute 6
peroxidase 6
lipase 6
endoplasmic reticulum 6
superoxide dismutase 6
beta-endorphin 6
MMP-2 5
phosphatase 5
cathepsin B 5
rhodopsin kinase 5
thyroglobulin 5
Boc 5
galactosyltransferase 5
Rhodopsin 5
PLS 5
spermatozoa 5
dihydrofolate reductase 5
atrial natriuretic factor 5
cysteine protease 5
insulin-degrading enzyme 5
lactoperoxidase 5
glutathione S-transferase 5
zinc metalloendopeptidase 5
proteoglycan 5
histone 5
PCC 5
L12 5
acetylcholine receptor 5
cysteine proteinase 5
CBS 5
nicotinic acetylcholine receptor 5
Nle 5
ferredoxin 5
MMP-1 5
HA2 5
endothelin-1 4
reductase 4
tissue inhibitor of metalloproteinases 4
PGA 4
more...
Disease
SDS 68
tumor 20
hypertension 15
cancer 15
mole 13
mole 13
cholera 9
influenza 8
tetanus 7
stomatitis 7
cold 7
neuroblastoma 6
multiple myeloma 6
arthritis 6
Legionella 5
PCC 5
pheochromocytoma 5
carcinoma 5
fibrosarcoma 5
Weaver 5
sarcoma 5
West 5
atherosclerosis 5
PLS 4
scrapie 4
leptospirosis 4
melanoma 4
leukemia 4
spongiform encephalopathy 4
pertussis 3
Proteus 3
heart failure 3
SAR 3
colon cancer 3
dehydration 3
sepsis 3
gastroenteritis 3
congestive heart failure 3
PDB 3
fibroma 2
anthrax 2
type 2 diabetes 2
osteoarthritis 2
nephrotic syndrome 2
diphtheria 2
SCH 2
Barrett's esophagus 2
plaque 2
cardiovascular disease 2
GSH 2
HIV 2
glioblastoma 2
diabetes 2
Tag 2
immunodeficiency 2
choriocarcinoma 2
fits 2
abdominal aortic aneurysm 2
Dissociation 2
BSE 2
MLS 2
Creutzfeldt-Jakob disease 2
infectious diseases 2
avian leukosis 2
malaria 2
NPS 2
Still 2
premature aging 2
rheumatoid arthritis 2
cornea 2
progeria 2
warts 1
hypothyroidism 1
Brucella abortus 1
Chlamydia 1
PDP 1
TEM 1
Pancreas 1
type 1 diabetes 1
Bordetella 1
NLS 1
vCJD 1
TEM 1
encephalitis 1
Shiga 1
myopathy 1
Tick-borne encephalitis 1
LTD 1
encephalomyelitis 1
Mycobacterium 1
Haemophilus 1
psoriasis 1
zoonosis 1
fungal infection 1
SCP 1
Sander 1
Goldstein 1
progressive supranuclear palsy 1
osteosarcoma 1
Lyme disease 1
HHP 1
anaphylaxis 1
breast cancer 1
chondrodysplasia 1
leprechaunism 1
Lederer 1
EVA 1
Huntington's disease 1
PAF 1
Gerstmann 1
Rous sarcoma 1
Thymus 1
Gilbert 1
squamous cell carcinoma 1
Cryptococcus neoformans 1
acute pancreatitis 1
transitional cell carcinoma 1
PKS 1
TOC 1
retinoblastoma 1
EDC 1
Sutton 1
tumorigenesis 1
BDB 1
lung carcinoma 1
polyneuropathy 1
EDA 1
juvenile rheumatoid arthritis 1
pemphigoid 1
NS2 1
PCP 1
vaccinia 1
lymphogranuloma venereum 1
PCA 1
corneal dystrophy 1
dysplasia 1
SARS 1
glomerulonephritis 1
RCM 1
tuberculosis 1
LBD 1
diabetic nephropathy 1
lung cancer 1
HHH 1
lymphoma 1
membranous nephropathy 1
sarcoidosis 1
smallpox 1
IVF 1
aggression 1
tularemia 1
Duchenne muscular dystrophy 1
MTC 1
leeches 1
hyperglycemia 1
macular degeneration 1
EPS 1
SCS 1
ventricular hypertrophy 1
nephrogenic diabetes insipidus 1
more...
Symptom
collapse 3
agitation 2
bitter taste 2
diarrhea 2
analgesia 2
pain 2
fatigue 1
autodigestion 1
tense 1
skin damage 1
Catch 1
anesthesia 1
cardiovascular impairment 1
acidity 1
eds 1
Drug
Asn 53
lysine 53
Gel 11
Biopolymers 10
Pronase 10
Dermatol 9
NADH 8
BoNT/A 8
Fragment 7
Papain 7
CaCl2 5
CaCl2 5
CaCl2 5
Phosphoramidon 4
L-tyrosine 4
Aprotinin 3
uPA 3
pyridoxal phosphate 3
NaI 2
DNase I 2
DFP 2
lactose 2
ascorbate 2
Leaf 2
NaI 2
NaI 2
NaI 2
Nephron 2
Fraction 2
PTH 2
Glycerol 2
Bromelain 1
TRM 1
caffeine 1
Maltose 1
Myotrophin 1
balanced salt solution 1
MTC 1
Tenatoprazole 1
Glutathione 1
LMWH 1
citric acid 1
Dakar 1
Cibacron Blue 1
Glucagon 1
Glutamic acid 1
Riboflavin 1
Human Serum Albumin 1
Hypaque 1
Cardiovasc 1
NH3 1
linolenate 1
Gelatin 1
PCP 1
MAP 1
Hypaque 1
Protamine sulfate 1
Triclosan 1
Adriamycin 1
CSF 1
NAG 1
Meth 1
Bevacizumab 1
CTX 1
PE2 1
Ethanol 1
FAD 1
Nephron 1
Scopolamine 1
Gly-Tyr-Gly 1
Violaxanthin 1
Enzyme
thermolysin 1894
trypsin 463
chymotrypsin 276
subtilisin 118
elastase 109
CD10 105
pepsin 100
papain 97
collagenase 68
ACE 54
proteinase K 46
thrombin 44
carboxypeptidase A 44
lysozyme 29
plasmin 24
endoproteinase Glu-C 22
ATPase 20
RNase 20
CD13 19
kallikrein 19
protein kinase 19
MMP-3 16
pseudolysin 16
astacin 16
proteasome 15
urokinase-type plasminogen activator 15
cathepsin G 15
neuraminidase 15
ERK 14
bromelain 14
renin 14
RNase 13
peroxidase 12
ribonuclease 11
alkaline phosphatase 11
ribonuclease 11
alpha-amylase 10
phospholipase A2 10
phosphorylase 10
transglutaminase 10
lysyl endopeptidase 10
bacillolysin 10
neutrophil elastase 10
botulinum neurotoxin 9
thimet oligopeptidase 9
thromboplastin 9
ficin 9
lipase 8
RNA polymerase 8
peptide deformylase 8
vibriolysin 7
endoproteinase Asp-N 7
phospholipase C 7
ACS 7
carboxypeptidase Y 7
AMPK 7
cathepsin D 7
superoxide dismutase 7
clostripain 7
leucine aminopeptidase 7
serralysin 6
chymosin 6
proteinase A 6
carbonic anhydrase 6
alpha-lytic protease 6
phosphodiesterase 6
alcohol dehydrogenase 6
protochlorophyllide oxidoreductase 6
lactate dehydrogenase 6
Pla 6
glutathione S-transferase 6
caspase-1 6
mitogen-activated protein kinase 6
deaminase 6
aureolysin 5
prolyl endopeptidase 5
protein kinase C 5
rhodopsin kinase 5
endothelin-converting enzyme 5
dihydrofolate reductase 5
insulin-degrading enzyme 5
cathepsin B 5
beta-lactamase 4
creatine kinase 4
neurolysin 4
phospholipase D 4
pyruvate kinase 4
endothiapepsin 4
aspartate aminotransferase 4
PST 4
catalase 4
enkephalinase B 4
adamalysin 4
DNase 4
myosin light chain kinase 4
hatching enzyme 4
MDP 4
glutamate dehydrogenase 4
tetanus neurotoxin 4
LTA4 hydrolase 4
glutamate dehydrogenase 4
glutamate dehydrogenase 4
tissue plasminogen activator 3
APC 3
furin 3
matrix metalloproteinase 9 3
oligopeptidase B 3
DNA ligase 3
acid phosphatase 3
carboxypeptidase B 3
beta-glucuronidase 3
MMP 3
GGGT 3
DNA ligase 3
calcium pump 3
glutamine synthetase 3
PGM 3
beta-galactosidase 3
RNase H 3
interstitial collagenase 3
acetylcholinesterase 3
cathepsin L 3
acrosin 2
MEK 2
neutrophil collagenase 2
xylose isomerase 2
starch synthase 2
clotting enzyme 2
meprin 2
gamma-glutamyl transpeptidase 2
DD-carboxypeptidase 2
cGMP phosphodiesterase 2
PNGase F 2
cytochrome oxidase 2
matrix metalloproteinase 2 2
aminopeptidase A 2
calcineurin 2
KLK7 2
lactose synthetase 2
NADPH-diaphorase 2
proteinase A 2
cytochrome c peroxidase 2
diaphorase 2
HIV-1 protease 2
aldolase 2
transhydrogenase 2
PRA 2
cathepsin C 2
tyrosinase 2
tissue kallikrein 2
Rex 2
demethylase 2
acyl-CoA thioesterase 2
chymopapain 2
chitinase 2
glycerol kinase 2
phosphorylase kinase 2
triphosphatase 2
reverse transcriptase 2
hypodermin C 2
more...
Compound
zinc 274
Phe 190
leucine 183
alanine 178
Dec 163
Gly 149
arginine 136
water 127
lysine 126
tyrosine 117
Asp 114
serine 111
NH2 109
calcium 105
His 100
cysteine 97
sodium 90
Ile 88
methionine 85
bromide 81
sulfate 75
threonine 75
SDS 72
hydrogen 65
tryptophan 54
tryptophan 52
tryptophan 51
tryptophan 51
EDTA 49
EDTA 49
DNA 49
urea 41
salt 40
phosphate 39
ATP 34
proline 33
glutamic acid 32
guanidine 30
acetate 30
ethanol 26
oxygen 25
cobalt 25
glutamate 24
Trypsin 24
ammonium 24
galactose 23
valine 22
aspartic acid 21
L-leucine 20
DEAE 19
ADP 18
ethyl acetate 17
aspartic acid 16
glycerol 16
glucose 16
HCl 16
iron 15
nitrogen 15
methanol 15
ADP 15
ADP 15
glutamine 15
copper 14
aspartic acid 14
aspartic acid 14
asparagine 14
isoleucine 13
acetic acid 12
Mg2+ 12
TOF 12
Triton X-100 12
isoleucine 12
manganese 11
hydroxylamine 11
GTP 11
hydroxylamine 11
phosphorus 10
COS 10
isopropanol 10
Clin 10
acetone 10
Pro-Gly 10
PEG 9
acetonitrile 9
NAD 9
NADH 8
PEG 8
chloroform 8
NADPH 7
ACS 7
Amide 7
Thiorphan 7
Collagenase 7
NAD 7
NADPH 7
ACS 7
cAMP 7
Tris 6
2-propanol 6
Tris 6
Cys-Gly 6
2-propanol 6
GalNAc 6
DMSO 6
Optimal 6
nitric oxide 6
alcohol dehydrogenase 6
UDP-galactose 6
GlcNAc 6
formic acid 5
formic acid 5
formic acid 5
Rhodopsin 5
cadmium 5
formic acid 5
potassium 5
hydroxide 5
formic acid 5
formic acid 5
formic acid 5
octyl 5
CBS 5
CaCl2 5
formic acid 5
acrylamide 5
phenol 5
formic acid 5
octyl 5
Cyanogen bromide 5
iodine 5
TCA 5
2-mercaptoethanol 5
octyl 5
hexose 5
formic acid 5
Phosphoramidon 4
NADP 4
Cystine 4
nickel 4
DMF 4
ammonia 4
AMP 4
palmitic acid 4
palmitic acid 4
Cystine 4
H2O2 4
1,2-cyclohexanedione 4
PMA 4
PMSF 4
1-propanol 4
aldehyde 4
sodium chloride 4
vinyl 4
aldehyde 4
MIA 3
Elastin 3
Cu(II) 3
HMM 3
phosphoserine 3
Azocoll 3
more...