Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.27 (
thermolysin
)
1,894
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
By Raman spectroscopic analysis we have determined the secondary structure of the promastigote surface protease, named
PSP
or gp63, of Leishmania major. It consist of nearly 50% antiparallel beta-strand, and less than 20% alpha-helix. These results are contrasted with the predominantly alpha-helical VSGs of the African trypanosomes and the alpha-helical metalloprotease
thermolysin
. The
PSP
of Leishmania thus represents a novel kind of membrane-anchored protease.
...
PMID:Secondary structure of the promastigote surface protease of Leishmania. 305 16
