Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.24.23 (MMP)
4,246 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MMP 3744 matrix metalloproteinase 1052 MMP-2 796 MMP-9 697 collagen 625 matrilysin 449 metalloproteinase 448 Mol 326 Sep 281 EPA 275 MMP-1 268 matrix metalloproteinase 2 245 TIMP-2 233 MMP-3 222 MMP9 201 TIMP 190 MT1-MMP 186 MMP-7 181 collagenase 161 stromelysin 150 caspase-3 150 ROS 149 fibronectin 145 MMP-13 141 cytokine 139 MMP7 128 TNF 125 p38 122 Bcl-2 118 MAPK 110 GSH 108 MMP2 105 ERK 104 IL-6 93 type I collagen 92 ERK1 87 urokinase-type plasminogen activator 87 vascular endothelial growth factor 85 tumor necrosis factor 84 JNK 80 VEGF 73 tissue inhibitor of metalloproteinases 72 E-cadherin 69 PI3K 68 MMP-8 65 MMP14 65 ECM 63 p53 62 ATP 59 matrix metalloprotease 59 MMP1 59 proteoglycan 59 hemopexin 59 aggrecan 58 metalloprotease 56 IL-8 56 elastin 55 AP-1 54 TIMP-3 54 AKT 52 PARP 51 plasminogen 51 caspase-9 49 cytochrome c 49 fur 47 matrix metalloproteinase 9 46 TNF-alpha 45 catenin 45 MMP-12 44 collagenase-3 43 membrane-bound 42 CD44 42 MMP3 42 MEK 41 lipopolysaccharide 40 SOD 39 EGFR 39 annexin V 39 IL-1 38 MT1 38 more...

Disease cancer 913 tumor 772 carcinoma 190 breast cancer 156 tumor progression 134 tumor growth 128 metastases 124 GSH 108 osteoarthritis 101 carcinogenesis 81 lung cancer 76 arthritis 76 MCF 72 atherosclerosis 68 tumorigenesis 68 prostate cancer 66 adenocarcinoma 65 colorectal cancer 65 colon cancer 63 hepatocellular carcinoma 61 rheumatoid arthritis 61 squamous cell carcinoma 60 fibrosarcoma 58 melanoma 58 glioma 57 plaque 50 hypertension 49 diabetes 42 ischemia 40 glioblastoma 40 gastric cancer 39 stroke 38 aggressiveness 37 myocardial infarction 35 Alzheimer's disease 34 ovarian cancer 34 cervical cancer 31 leukemia 29 pancreatic cancer 28 heart failure 28 SDS 26 tumor angiogenesis 24 epithelial ovarian cancer 24 osteosarcoma 23 cardiovascular disease 22 uterus 22 obesity 22 primary tumor 22 liver fibrosis 22 asthma 22 periodontitis 21 multiple sclerosis 20 pulmonary fibrosis 19 cerebral ischemia 19 dysplasia 19 Parkinson's disease 18 chronic obstructive pulmonary disease 18 renal cell carcinoma 17 endometrial cancer 16 Mycobacterium 16 lung carcinoma 16 inflammatory bowel disease 16 glioblastoma multiforme 15 abdominal aortic aneurysm 14 emphysema 14 non-small cell lung cancer 14 arthropathy 14 neuroblastoma 13 adenoma 13 brain tumor 13 TEM 13 HGF 13 skin cancer 13 Blocking 13 lymphoma 13 mammary tumor 13 invasive cancer 13 TEM 12 cornea 12 renal disease 12 more...

Symptom collapse 21 pain 17 skin damage 6 acidity 6 thinning 5 dry eye 5 cough 4 functional recovery 4 anesthesia 4 angina 4 starvation 4 erythema 3 exhaustion 3 low back pain 3 weakness 3 Scratch 2 pelvic pain 2 seizures 2 arthralgia 2 wheezing 1 ataxia 1 discomfort 1 spasticity 1 nausea 1 exertional dyspnea 1 constipation 1 hyperoxia 1 hypothermia 1 muscle cramps 1 HSA 1 diarrhea 1 chest pain 1 discomfort 1 acute stress 1 snoring 1 Sore 1 Trembling 1 distraction 1 splenomegaly 1 dizziness 1 back pain 1 memory loss 1 dyspnea 1 shortness of breath 1 overweight 1 Fluctuation 1 fatigue 1 Chest discomfort 1 upset stomach 1 Wind 1 flushing 1 knee pain 1 joint stiffness 1 headache 1 neurological disability 1 spasm 1 skin irritation 1 swollen joints 1

Drug ROS 149 Gelatin 33 uPA 33 Dermatol 31 lysine 28 Cardiovasc 17 Asn 14 MAP 13 Batimastat 13 Batimastat 13 ascorbate 12 Monit 11 IFN-gamma 11 CTX 11 Gel 10 CTX 10 CTX 10 Marimastat 9 CSF 9 Doxycycline 8 Ilomastat 7 IL-2 6 Asthma 5 CAM 5 ADR 4 NADH 4 Angiotensin II 4 ROC 4 Glutathione 4 CaCl2 4 CaCl2 4 MRC 4 G-CSF 4 Arsenic trioxide 4 vitamin E 4 CaCl2 4 Emodin 3 PTH 3 DM1 3 p75 3 Emodin 3 EE2 3 Phosphatidylserine 3 Indomethacin 3 lactose 3 ZnO 3 Aprotinin 3 Heme 3 Ethanol 3 Fluorescein 3 Taxol 3 IFN-beta 3 Nitric Oxide 3 RFP 2 TAK 2 ADM 2 Prinomastat 2 Epigallocatechin 2 Auranofin 2 Fluorescein 2 Adriamycin 2 ABC 2 Histamine 2 Simvastatin 2 Propofol 2 NBT 2 Infliximab 2 Infliximab 2 Myricetin 2 Dakar 2 Leaf 2 BTC 2 BLM 2 Oseltamivir 2 G418 2 Rosiglitazone 2 Ouabain 2 Albumin 1 NOV 1 NAG 1 more...

Enzyme MMP 4246 collagenase 452 MMP-3 302 mitogen-activated protein kinase 270 matrix metalloproteinase 2 188 ERK 174 matrix metalloproteinase 9 159 caspase-3 120 urokinase-type plasminogen activator 107 focal adhesion kinase 86 interstitial collagenase 75 superoxide dismutase 60 MEK 59 PARP 56 plasmin 53 furin 47 protein kinase C 43 protein kinase 38 caspase-9 36 catalase 36 trypsin 35 elastase 34 reverse transcriptase 34 luciferase 31 tissue plasminogen activator 31 thrombin 30 stromelysin-3 22 peroxidase 21 macrophage elastase 21 TACE 20 caspase-8 20 CD10 19 alanine aminotransferase 16 proteasome 15 alkaline phosphatase 15 phosphatidylinositol 3-kinase 14 lactate dehydrogenase 14 neutrophil collagenase 14 NADPH oxidase 13 aspartate aminotransferase 13 glutathione S-transferase 13 renin 13 phosphoinositide 3-kinase 12 matrix metalloproteinase 14 12 NADPH oxidase 12 APC 12 GSK 12 AMP-activated protein kinase 11 cathepsin K 10 neutrophil elastase 10 AST 10 cathepsin B 10 ACS 10 RNA polymerase 10 phospholipase C 9 thiopurine methyltransferase 9 glutathione peroxidase 8 creatine kinase 8 transcriptase 8 proprotein convertase 8 MAP 8 MPP 8 phospholipase A2 8 NO synthase 7 AMPK 7 collagenase 3 7 lysozyme 7 cdc2 7 ATPase 7 hyaluronidase 6 RNase 6 RNase 6 glyceraldehyde-3-phosphate dehydrogenase 6 MIP 6 complex I 6 AMPK 6 cathepsin G 6 glyceraldehyde-3-phosphate dehydrogenase 5 kallikrein 5 type III procollagen 5 more...

Compound Dec 288 oxygen 258 DNA 203 Clin 137 zinc 136 TNF 125 GSH 110 GSH 110 calcium 96 cysteine 92 MDA 83 MTT 80 acetate 76 water 71 leucine 70 tyrosine 65 ASA 65 arginine 63 glucose 62 Gly 61 ATP 59 serine 59 alanine 56 Collagen 54 nitric oxide 46 sulfate 46 hydrogen 44 lysine 43 N-acetylcysteine 43 MEK 40 PEG 37 EDTA 36 EDTA 36 PEG 31 Asp 30 NH2 29 phosphate 28 proline 28 Panam 27 methionine 27 Collagenase 26 Phe 26 SDS 26 sodium 25 hyaluronic acid 24 THP 23 THP 23 ethanol 23 salt 22 retinoic acid 22 threonine 21 Cardiol 21 galactose 21 TACE 20 H2O2 20 Ang II 19 iodine 19 His 17 CAT 17 MEP 17 MEP 17 CAT 17 PGE2 17 CAT 17 PMA 16 COS 15 PMA 15 cAMP 15 TEM 14 BSO 14 DEHP 13 urea 13 iron 13 Cyt 13 nitrogen 13 gallic acid 12 Ile 12 PGE 12 ADP 12 copper 12 more...

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