Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.24.23 (MMP)
4,246 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MMP 3744 matrix metalloproteinase 1052 MMP-2 796 MMP-9 697 collagen 625 matrilysin 449 metalloproteinase 448 Mol 326 Sep 281 EPA 275 MMP-1 268 matrix metalloproteinase 2 245 TIMP-2 233 MMP-3 222 MMP9 201 TIMP 190 MT1-MMP 186 MMP-7 181 collagenase 161 caspase-3 150 stromelysin 150 ROS 149 fibronectin 145 MMP-13 141 cytokine 139 MMP7 128 TNF 125 p38 122 Bcl-2 118 MAPK 110 GSH 108 MMP2 105 ERK 104 IL-6 93 type I collagen 92 urokinase-type plasminogen activator 87 ERK1 87 vascular endothelial growth factor 85 tumor necrosis factor 84 JNK 80 more...

Disease cancer 913 tumor 772 carcinoma 190 breast cancer 156 tumor progression 134 tumor growth 128 metastases 124 GSH 108 osteoarthritis 101 carcinogenesis 81 arthritis 76 lung cancer 76 MCF 72 atherosclerosis 68 tumorigenesis 68 prostate cancer 66 colorectal cancer 65 adenocarcinoma 65 colon cancer 63 rheumatoid arthritis 61 hepatocellular carcinoma 61 squamous cell carcinoma 60 melanoma 58 fibrosarcoma 58 glioma 57 plaque 50 hypertension 49 diabetes 42 ischemia 40 glioblastoma 40 gastric cancer 39 stroke 38 aggressiveness 37 myocardial infarction 35 ovarian cancer 34 Alzheimer's disease 34 cervical cancer 31 leukemia 29 heart failure 28 pancreatic cancer 28 more...

Symptom collapse 21 pain 17 acidity 6 skin damage 6 dry eye 5 thinning 5 cough 4 starvation 4 anesthesia 4 angina 4 functional recovery 4 erythema 3 exhaustion 3 low back pain 3 weakness 3 Scratch 2 seizures 2 pelvic pain 2 arthralgia 2 wheezing 1 ataxia 1 discomfort 1 spasticity 1 nausea 1 exertional dyspnea 1 constipation 1 distraction 1 hypothermia 1 muscle cramps 1 splenomegaly 1 HSA 1 chest pain 1 snoring 1 back pain 1 Sore 1 discomfort 1 shortness of breath 1 upset stomach 1 Chest discomfort 1 joint stiffness 1 more...

Drug ROS 149 Gelatin 33 uPA 33 Dermatol 31 lysine 28 Cardiovasc 17 Asn 14 Batimastat 13 MAP 13 Batimastat 13 ascorbate 12 IFN-gamma 11 Monit 11 CTX 11 CTX 10 Gel 10 CTX 10 CSF 9 Marimastat 9 Doxycycline 8 Ilomastat 7 IL-2 6 CAM 5 Asthma 5 Angiotensin II 4 NADH 4 CaCl2 4 ADR 4 ROC 4 MRC 4 CaCl2 4 Arsenic trioxide 4 G-CSF 4 vitamin E 4 Glutathione 4 CaCl2 4 Emodin 3 EE2 3 ZnO 3 Taxol 3 more...

Enzyme MMP 4246 collagenase 452 MMP-3 302 mitogen-activated protein kinase 270 matrix metalloproteinase 2 188 ERK 174 matrix metalloproteinase 9 159 caspase-3 120 urokinase-type plasminogen activator 107 focal adhesion kinase 86 interstitial collagenase 75 superoxide dismutase 60 MEK 59 PARP 56 plasmin 53 furin 47 protein kinase C 43 protein kinase 38 caspase-9 36 catalase 36 trypsin 35 reverse transcriptase 34 elastase 34 luciferase 31 tissue plasminogen activator 31 thrombin 30 stromelysin-3 22 peroxidase 21 macrophage elastase 21 TACE 20 caspase-8 20 CD10 19 alanine aminotransferase 16 proteasome 15 alkaline phosphatase 15 neutrophil collagenase 14 lactate dehydrogenase 14 phosphatidylinositol 3-kinase 14 glutathione S-transferase 13 renin 13 more...

Compound Dec 288 oxygen 258 DNA 203 Clin 137 zinc 136 TNF 125 GSH 110 GSH 110 calcium 96 cysteine 92 MDA 83 MTT 80 acetate 76 water 71 leucine 70 tyrosine 65 ASA 65 arginine 63 glucose 62 Gly 61 ATP 59 serine 59 alanine 56 Collagen 54 nitric oxide 46 sulfate 46 hydrogen 44 lysine 43 N-acetylcysteine 43 MEK 40 PEG 37 EDTA 36 EDTA 36 PEG 31 Asp 30 NH2 29 proline 28 phosphate 28 methionine 27 Panam 27 more...

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