Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.23 (
MMP
)
4,246
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MMP
3744
matrix metalloproteinase
1052
MMP-2
796
MMP-9
697
collagen
625
matrilysin
449
metalloproteinase
448
Mol
326
Sep
281
EPA
275
MMP-1
268
matrix metalloproteinase 2
245
TIMP-2
233
MMP-3
222
MMP9
201
TIMP
190
MT1-MMP
186
MMP-7
181
collagenase
161
stromelysin
150
more...
Disease
cancer
913
tumor
772
carcinoma
190
breast cancer
156
tumor progression
134
tumor growth
128
metastases
124
GSH
108
osteoarthritis
101
carcinogenesis
81
lung cancer
76
arthritis
76
MCF
72
atherosclerosis
68
tumorigenesis
68
prostate cancer
66
colorectal cancer
65
adenocarcinoma
65
colon cancer
63
hepatocellular carcinoma
61
more...
Symptom
collapse
21
pain
17
acidity
6
skin damage
6
thinning
5
dry eye
5
angina
4
functional recovery
4
anesthesia
4
cough
4
starvation
4
exhaustion
3
low back pain
3
weakness
3
erythema
3
seizures
2
pelvic pain
2
Scratch
2
arthralgia
2
hypothermia
1
more...
Drug
ROS
149
uPA
33
Gelatin
33
Dermatol
31
lysine
28
Cardiovasc
17
Asn
14
MAP
13
Batimastat
13
Batimastat
13
ascorbate
12
IFN-gamma
11
Monit
11
CTX
11
Gel
10
CTX
10
CTX
10
Marimastat
9
CSF
9
Doxycycline
8
more...
Enzyme
MMP
4246
collagenase
452
MMP-3
302
mitogen-activated protein kinase
270
matrix metalloproteinase 2
188
ERK
174
matrix metalloproteinase 9
159
caspase-3
120
urokinase-type plasminogen activator
107
focal adhesion kinase
86
interstitial collagenase
75
superoxide dismutase
60
MEK
59
PARP
56
plasmin
53
furin
47
protein kinase C
43
protein kinase
38
catalase
36
caspase-9
36
more...
Compound
Dec
288
oxygen
258
DNA
203
Clin
137
zinc
136
TNF
125
GSH
110
GSH
110
calcium
96
cysteine
92
MDA
83
MTT
80
acetate
76
water
71
leucine
70
ASA
65
tyrosine
65
arginine
63
glucose
62
Gly
61
more...