Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.23 (MMP)
 4,246 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
splicing factor p54 12.9
myelodysplasia/myeloid leukemia factor 2 12.9
MMP 12.9
matrilysin 12.5
Astrotactin 1 11.9
PSG9 protein 11.9
ALL1-fused gene from chromosome 1q 11.9
SPOCK2 protein 11.9
Kinesin family member 1B 11.9
MMP-23 11.7
Metalloelastase 11.7
low density lipoprotein-related protein 1 11.3
PHD finger protein 23 11.3
ITGB1BP3 11.3
PLGL 11.2
MMP-27 11.1
ZMAT2 10.9
Cas-interacting zinc finger protein 10.9
YIPF2 10.9
PLCE1 protein 10.9
MMP7 10.9
TIMP 10.8
MT2-MMP 10.7
MMP-7 10.7
MT6-MMP 10.6
PLA2G12B 10.6
Cell surface glycoprotein 10.6
ZNF139 10.6
metalloelastase 10.4
MIFR 10.4
tissue inhibitor of metalloproteinases-2 10.4
MMP-26 10.4
expressed in pancreatic carcinoma 10.3
PLA2G12A 10.3
epilysin 10.3
stromelysin-3 10.2
MMP-25 10.2
MMP-21 10.1
CYP2B7P1 10.1
Matrix metalloproteinase 11 10.1
matrix metalloproteinase 10 10.1
MMP-11 10.0
matrix metalloproteinase 11 10.0
MT4-MMP 9.9
LIM domain kinase 2 9.9
Lutheran blood group glycoprotein 9.9
sPLA(2)-IIF 9.9
transmembrane 4 L six family member 5 9.9
Angiopoietin-like 2 9.9
MT1-MMP 9.8
SPOCK2 9.8
MT5-MMP 9.8
MMP14 9.7
MMP23B 9.7
leukolysin 9.7
PLD 1 9.7
COL6A6 9.7
PLA2G2D 9.7
neuronal K-Cl cotransporter 9.7
MMP-28 9.6
TIMP-2 9.6
collagenase-3 9.6
MMP25 9.6
cytochrome c, somatic 9.6
BLID 9.6
advanced glycosylation end product-specific receptor 9.6
FBP21 9.6
K-rev 9.6
TCTEL1 9.6
calcium binding and coiled-coil domain 2 9.6
TIMP-4 9.5
regulator of G-protein signaling 16 9.4
E1A-F 9.4
TIMM23 9.4
Mucin 4 9.4
RHBDL2 9.4
Type XIV collagen 9.4
KIP3 9.4
aggrecanase-1 9.4
MMP-2 9.4
Matrix metalloproteinase 1 9.3
stromelysin 9.3
matrix metalloproteinase 2 9.3
MMP-3 9.3
MMP8 9.3
matrix metalloproteinase 1 9.3
ADAM-15 9.3
TOM1L1 9.3
MMP28 9.3
matrix metalloproteinase 20 9.2
MMP-13 9.2
TIMP-3 9.2
SM3 9.2
PLA2G10 9.2
ADAM21 9.2
PHF23 9.2
metalloprotease disintegrin 9.2
MMP-1 9.1
RECK 9.1
Metalloproteinase 9.1
Matrix metalloproteinase 9 9.1
CREB3L3 9.1
matrix metalloproteinase 16 9.1
PCDH8 9.1
metalloproteinase-disintegrin 9.1
TSPAN2 9.1
MMP1 9.0
canstatin 9.0
TIMP2 9.0
FBP-interacting repressor 9.0
AMIDA 9.0
Trypsin-2 9.0
matrix metalloproteinase 3 9.0
matrix metalloproteinase 8.9
MMP-12 8.9
ADAMDEC1 8.9
MMP-9 8.9
G6PT 8.9
KAI1 protein 8.9
G1L 8.9
MMP-10 8.8
VPS1 8.8
metalloproteinase 8.8
MMP-8 8.8
tesmin 8.8
Extracellular signal-regulated kinase 3 8.8
NRE-binding protein 8.8
TIMP1 8.8
MMP3 8.8
MSPL 8.7
metastasis associated protein 8.7
ATP8A1 8.7
CNK1 8.7
matrix metalloproteinase 12 8.7
tissue inhibitor of metalloproteinases 8.7
MMP12 8.7
DEFA4 8.6
OGFr 8.6
PLA2G3 8.6
CTNNAL1 8.6
L3MBTL3 8.6
annexin A10 8.6
MCSP 8.6
MMP15 8.6
hemopexin 8.6
MMP11 8.6
CTNNBIP1 8.6
ATP6L 8.6
PTPRS 8.6
ADAMTS4 8.5
ADAMTS15 8.5
kallikrein-like serine protease 8.5
MMP-19 8.5
Tissue inhibitor of metalloproteinase 1 8.5
MYBPC1 8.5
COX5B 8.5
Thrombospondin-2 8.5
MMP13 8.5
BRD1 8.5
matrix metalloprotease 8.4
more...
Disease
Canine elbow dysplasia 10.6
Hypervitaminosis D 9.2
PHA2 8.9
Antrochoanal polyp 8.8
Fowl cholera 8.6
Elastolysis 8.5
Primary angle-closure glaucoma 8.3
Macroangiopathy 8.2
Nodular glomerulosclerosis 8.1
Familial amyloidosis 7.6
PB leprosy 7.6
Alveolitis 7.6
chronic nasopharyngitis 7.4
EBSS 7.3
Pancreatic Ductal Adenocarcinoma 7.3
Pancreatic Ductal Adenocarcinoma 7.3
VED 7.2
Aortic valve calcification 7.2
adult glioblastoma 6.9
FGD1 6.9
photokeratitis 6.9
CLL progression 6.7
Bergeron 6.7
anetoderma 6.6
hypertensive nephropathy 6.6
salivary gland cancer 6.6
berry aneurysm 6.5
Supravalvular aortic stenosis 6.4
Miliary tuberculosis 6.4
rotator cuff syndrome 6.4
tooth resorption 6.2
cerebrovascular occlusion 6.1
COL2A1 6.1
Malignant glioma 6.1
Thoracic aortic aneurysm 6.1
polydrug abuse 6.0
frozen shoulder 5.9
hypopharyngeal squamous cell carcinoma 5.9
fibrosarcoma 5.9
Neurodegenerative Disorders 5.8
SOST 5.8
cancer angiogenesis 5.8
Postoperative infection 5.7
ovarian serous cystadenocarcinoma 5.7
Mucous membrane pemphigoid 5.7
OHS 5.7
Retinal ischemia 5.6
lymphoblastoma 5.6
Cardiac rupture 5.5
erythroplakia 5.5
radioulnar synostosis 5.5
Fibrosarcoma 5.4
pancreatic fibrosis 5.4
Tendinopathy 5.4
UIP 5.4
XFS 5.3
arthritis of the knee 5.3
Malassez 5.3
Chemoradiation 5.3
HGF 5.2
anaplastic thyroid cancer 5.2
stage III colon cancer 5.2
retrograde menstruation 5.2
occupational lung disease 5.2
epithelial tumor 5.1
Kashin-Beck disease 5.1
lymphoid neoplasm 5.1
ST3 5.1
neurogenic hypertension 5.1
bone marrow metastases 5.1
Chondrosarcoma 5.1
Chondrosarcoma 5.1
BOS 5.1
PPB 5.0
MPE 5.0
Pseudomonas infection 5.0
Simpson-Golabi-Behmel syndrome 5.0
Kidney Cancer 5.0
invasive cancer 5.0
squamous cell carcinoma of the skin 4.9
gnathostomiasis 4.9
tumor angiogenesis 4.9
Ellis-van Creveld syndrome 4.9
Mesothelioma 4.9
IDD 4.9
PARK2 4.9
pregnancy disorder 4.9
disc degeneration 4.8
Mycoplasma pneumoniae pneumonia 4.8
sialidosis 4.8
local cancer 4.8
acute cystitis 4.7
AGS 4.7
ovarian dysfunction 4.7
East Coast fever 4.7
Hypertrophic 4.7
rhinovirus infection 4.7
JIP 4.6
autoimmune lymphoproliferative syndrome 4.6
MEC 4.6
brain cancer 4.6
tumor progression 4.6
Vascular lesions 4.6
ventricular failure 4.6
blood cancer 4.6
Osteosarcoma 4.6
Osteosarcoma 4.6
diffuse scleroderma 4.6
EMT 4.6
chondrolysis 4.5
Canine distemper 4.5
pharyngeal cancer 4.5
OCP 4.5
aggressiveness 4.5
recurrent prostate cancer 4.5
Esophageal squamous cell carcinoma 4.5
trophoblastic tumor 4.5
metastatic osteosarcoma 4.5
Dukes 4.5
glutaric aciduria 4.4
Dermal 4.4
osteoarthritis 4.4
GSH 4.4
FBS 4.4
HEP 4.4
pemphigoid 4.4
biventricular failure 4.4
HNSCC 4.4
pancreatic neoplasm 4.4
Diabetic neuropathy 4.4
Primary open-angle glaucoma 4.3
trichothiodystrophy 4.3
Granuloma 4.3
LDLR 4.3
pulmonary fibrosis 4.3
liver fibrosis 4.3
cardiosclerosis 4.3
tubal pregnancy 4.3
Inflammatory Bowel Disease 4.3
MCF 4.3
enchondroma 4.2
Bronchiolitis obliterans 4.2
CLS 4.2
PIT 4.2
KMS 4.2
ASM 4.1
Papilloma 4.1
acute monocytic leukemia 4.1
keratocyst 4.1
malignant ascites 4.1
CEP 4.1
CHR 4.1
pachymeningitis 4.0
colon cancer 4.0
dry eye syndrome 4.0
glioblastoma 4.0
venous disease 4.0
tumor growth 4.0
Septic arthritis 4.0
ischemic colitis 4.0
more...
Symptom
Chest discomfort 8.9
Trembling 8.2
Sore 8.1
upset stomach 8.0
Scratch 5.2
skin damage 4.9
dry eye 3.8
swollen joints 3.8
Fluctuation 3.6
muscle cramps 3.1
neurological disability 3.0
joint stiffness 2.8
collapse 2.5
pelvic pain 1.9
skin irritation 1.8
thinning 1.7
acidity 1.6
Wind 1.5
knee pain 1.4
snoring 1.4
HSA 1.3
low back pain 1.2
functional recovery 1.2
exertional dyspnea 1.1
arthralgia 1.1
memory loss 1.1
erythema 0.8
exhaustion 0.7
acute stress 0.7
wheezing 0.6
shortness of breath 0.5
hyperoxia 0.5
angina 0.5
cough 0.3
starvation 0.3
flushing 0.2
spasticity 0.2
spasm 0.0
distraction -0.3
dizziness -0.4
splenomegaly -0.4
constipation -0.4
back pain -0.7
weakness -0.8
pain -1.0
ataxia -1.1
chest pain -1.2
hypothermia -1.2
discomfort -1.6
nausea -1.6
discomfort -1.7
overweight -1.8
anesthesia -1.9
dyspnea -1.9
seizures -2.4
fatigue -2.8
headache -2.9
diarrhea -2.9
Drug
S-Adenosyl-L-Homocysteine 12.9
Condurango 11.9
Ilomastat 10.4
Trocade 10.3
Clamoxyl 10.3
Batimastat 10.0
Batimastat 10.0
Marimastat 9.9
Prinomastat 9.7
Urso 8.2
Mercaptopurine 7.5
Cilomilast 7.5
Sivelestat 7.3
Gelatin 7.2
Aclarubicin 7.1
Lercanidipine 7.0
uPA 6.9
Zebularine 6.7
Ciglitazone 6.6
Tolfenamic acid 6.5
Bosutinib 6.3
Trilostane 6.1
Lutalyse 5.9
ROS 5.9
Doxycycline 5.8
Rebamipide 5.6
ROX 5.6
Myricetin 5.6
Emodin 5.6
Monosodium glutamate 5.5
2-Methoxyestradiol 5.5
Auranofin 5.5
Casodex 5.3
Emodin 5.3
Tranilast 5.2
Flavopiridol 5.2
NOV 5.1
Epigallocatechin 5.1
Phosphatidylserine 5.1
Anakinra 4.9
CER 4.8
CLS 4.7
BTC 4.7
Aprotinin 4.6
Oseltamivir 4.6
Arsenic trioxide 4.6
Codeine 4.5
Codeine 4.4
Felodipine 4.3
Rosiglitazone 4.2
CTT 4.2
LCM 4.1
LCM 4.1
Hyaluronidase 4.0
Moxifloxacin 4.0
Ginger 4.0
Cibacron Blue 4.0
KGF 4.0
Hyaluronidase 3.9
TAK 3.9
Zoledronic acid 3.9
Glutamic acid 3.9
ADR 3.9
DM1 3.8
Adalimumab 3.8
CTX 3.7
Infliximab 3.7
Infliximab 3.7
CTX 3.7
RFP 3.6
Urokinase 3.6
VCR 3.6
R1881 3.6
Glide 3.6
NBT 3.5
BLM 3.5
Raloxifene 3.4
Zoledronic acid 3.2
Pravastatin 3.2
Simvastatin 3.2
Asn 3.2
MRC 3.1
Nitric Oxide 3.1
CTX 3.0
Cetuximab 3.0
NVP 2.9
IFN-beta 2.9
Heme 2.9
Luteinizing 2.8
Propofol 2.8
Taxol 2.8
Dakar 2.8
IL-11 2.8
G418 2.7
CAM 2.7
AMC 2.7
Gefitinib 2.7
MAP 2.6
Aloe 2.6
Azithromycin 2.6
CoCl2 2.6
CoCl2 2.6
Fluorescein 2.6
Ouabain 2.6
DPA 2.6
Angiotensin II 2.6
CCL 2.5
p75 2.5
ZnCl2 2.5
ZnCl2 2.5
G-CSF 2.5
Glutathione 2.5
Fluorescein 2.5
Meth 2.5
IL-1ra 2.5
Glycyrrhiza 2.4
IPM 2.3
Gel 2.3
Bortezomib 2.3
balanced salt solution 2.3
Allergen 2.3
ADM 2.3
Bayer 2.2
VCR 2.2
CaCl2 2.2
CaCl2 2.2
Triclosan 2.2
CaCl2 2.2
Ginseng 2.2
Activin 2.1
Parkin 2.0
TTC 2.0
Parkin 2.0
CPT-11 2.0
ascorbate 2.0
ROC 2.0
Itraconazole 1.9
Theophylline 1.9
lysine 1.8
Indomethacin 1.8
EPI 1.8
NAG 1.8
Paraffin 1.8
Estrogens 1.7
PTH 1.7
Herceptin 1.7
Adriamycin 1.7
TAT 1.6
EE2 1.5
IFN-gamma 1.5
ETS 1.5
Histamine 1.4
Alanine 1.4
ALA 1.4
Growth hormone 1.3
Vitamin A 1.3
Growth hormone 1.3
Monit 1.2
Ethanol 1.2
Atropine 1.2
more...
Enzyme
MMP 12.9
matrilysin-2 10.9
stromelysin-3 10.3
macrophage elastase 10.1
matrix metalloproteinase 14 10.0
collagenase 3 9.7
MMP-3 9.4
matrix metalloproteinase 2 9.2
aggrecanase-1 9.2
interstitial collagenase 9.2
neutrophil collagenase 9.1
matrix metalloproteinase 9 9.1
oxalyl-CoA decarboxylase 8.8
deuterolysin 8.3
hatching enzyme 7.9
matrix metalloproteinase-20 7.7
TACE 7.6
collagenase 7.5
sphingomyelinase D 7.1
thiopurine methyltransferase 6.9
furin 6.8
carboxyl proteinase 6.6
urokinase-type plasminogen activator 6.2
procollagen C-proteinase 6.2
astacin 5.9
lysyl hydroxylase 5.9
matriptase 5.9
matriptase 5.9
proprotein convertase 5.8
type III procollagen 5.8
hepsin 5.7
hepsin 5.7
N-acetylglucosaminyltransferase V 5.6
endothelin-converting enzyme 5.6
cathepsin S 5.5
plasmin 5.5
TSR 5.4
cathepsin H 5.4
cathepsin K 5.3
histidyl-tRNA synthetase 5.3
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.2
caspase-9 5.2
pregnancy-associated plasma protein-A 5.2
glutaryl-CoA dehydrogenase 5.1
MPP 5.0
PARP 4.9
endo-beta-galactosidase 4.9
elastase 4.8
biliverdin reductase 4.7
TSP-1 4.7
caspase-3 4.7
cathepsin G 4.6
dimethylarginine dimethylaminohydrolase 4.6
MEK 4.6
lysyl oxidase 4.6
neutral sphingomyelinase 4.5
enterokinase 4.5
caspase-8 4.5
mitogen-activated protein kinase 4.4
tissue plasminogen activator 4.4
nicotinamide phosphoribosyltransferase 4.3
CEP 4.3
FAST 4.3
legumain 4.3
dUTPase 4.2
m-calpain 4.2
neutrophil elastase 4.2
cathepsin B 4.2
endoproteinase Glu-C 4.2
heparinase 4.1
Protein 2 4.1
PTR 4.1
chymase 4.1
NPL 4.0
polyamine oxidase 4.0
phosphoinositide 3-kinase 3.9
carboxypeptidase A 3.9
BAL 3.9
prolidase 3.9
Hageman factor 3.9
focal adhesion kinase 3.9
angiotensin-converting enzyme 2 3.9
CD10 3.9
CYP27A1 3.8
ERK 3.8
CEP 3.8
meprin 3.8
HK2 3.8
GSK 3.7
CDH 3.7
prolyl hydroxylase 3.6
AST 3.6
prenyltransferase 3.6
tissue kallikrein 3.6
15-hydroxyprostaglandin dehydrogenase 3.6
CPS 3.6
thermolysin 3.6
DCF 3.5
cathepsin L 3.5
SMP 3.5
mu-calpain 3.5
tryptase 3.4
E-2 3.4
insulin-degrading enzyme 3.3
arginase 3.3
MAT 3.3
MCS 3.3
peptidyl-prolyl cis-trans isomerase 3.3
phosphatidylinositol 3-kinase 3.2
prolyl endopeptidase 3.2
ubiquitin-protein ligase 3.2
MIP 3.2
NADPH oxidase 3.1
12-lipoxygenase 3.1
NADPH oxidase 3.1
MAT 3.1
aconitase 3.1
ALDH 3.1
p100 3.1
CD13 3.1
endoglycosidase H 3.0
prostaglandin synthetase 3.0
hyaluronidase 3.0
MAP 3.0
3beta-hydroxysteroid dehydrogenase 3.0
reverse transcriptase 3.0
glyceraldehyde-3-phosphate dehydrogenase 3.0
cholesterol esterase 3.0
TdT 3.0
GAS 3.0
superoxide dismutase 2.9
SCS 2.9
PTPase 2.9
RNase III 2.9
chloramphenicol acetyltransferase 2.9
hyaluronidase 2.9
AMPK 2.8
HIV-1 protease 2.8
STR 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
thrombin 2.8
3-hydroxy-3-methylglutaryl-CoA reductase 2.7
glyceraldehyde-3-phosphate dehydrogenase 2.7
protein kinase C 2.7
transcriptase 2.7
AMP-activated protein kinase 2.7
cdc2 2.7
TSA 2.6
trypsin 2.6
Thy1 2.6
kallikrein 2.6
luciferase 2.6
DNA methyltransferase 2.6
phospholipase D 2.6
kinesin 2.6
sialidase 2.5
myosin light chain kinase 2.5
APC 2.5
more...
Compound
2-allyl-4-chlorophenol 12.9
2-phenyl-1,3-thiazinane 12.9
2-allyl-4-bromophenol 12.9
C21H19NO4S 11.9
Withaperuvin B 11.9
C21H19NO4S 11.9
C21H19NO4S 11.9
2-Amino-3-hydroxypyridine 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C21H19NO4S 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 11.3
C15H10O5 10.9
C15H10O5 10.9
Zaluzanin C 10.9
C15H10O5 10.9
6-Methylmercaptopurine 10.9
C9H7NO 10.6
6-Methoxypurine 10.6
C15H10O5 10.6
2-allyl-4-methoxyphenol 10.3
GW 1929 10.3
BCDR 10.1
diisopropyl phthalate 10.1
Diphyllin 9.9
Licarin A 9.7
4-(4-methylphenyl)-4-oxobutanoic acid 9.4
C15H14O3 9.4
MMTP 9.4
Propyl gallate 9.4
2,3-dihydro-1,4-benzodioxine 9.2
Jatrorrhizine 9.1
A 172 9.1
Funiculosin 9.0
Lucidin 9.0
Petunidin 8.9
Azocoll 8.8
Triacetic acid lactone 8.7
2-Hydroxyquinoline 8.7
Matairesinol 8.7
Vicenin-2 8.5
Sulfuretin 8.2
I acid 8.2
LLY 8.1
Actinonin 8.1
Acetylshikonin 8.0
Oseltamivir phosphate 7.8
triphenylarsine 7.8
Purpurin 7.8
PBNA 7.8
Solasodine 7.8
Patchouli alcohol 7.8
Pyrogallol 7.8
GW 9662 7.7
4-methylmorpholine 7.7
Collagenase 7.6
Sclareol 7.6
stigmast-4-en-3-one 7.6
TACE 7.5
Laminariaceae 7.5
dimethyl succinate 7.4
2-methyl-2-butanol 7.3
Nafoxidine 7.3
PTMA 7.3
2-methyl-2-butanol 7.2
MCPP 7.2
MIBK 7.2
Buthionine sulfoximine 7.1
Alantolactone 7.1
Granulin 7.1
BSO 7.1
2-methoxy-4-methylphenol 7.1
thiirane 7.0
MEP 7.0
Nobiletin 7.0
ara-AMP 6.9
ara-AMP 6.9
Acacetin 6.9
4-methyl-2-pentanone 6.9
4-methyl-2-pentanone 6.9
Carnosol 6.9
MEP 6.8
CH3NO2 6.8
Glabridin 6.7
2-methyl-2-propanol 6.7
2-methyl-2-propanol 6.7
Cucurbitacin B 6.7
3-Nitrotyrosine 6.6
Pinocembrin 6.6
Butein 6.6
PD 123177 6.5
Amprenavir 6.5
FMI 6.4
Borneol 6.3
PMP 6.3
succinamide 6.3
PMP 6.3
RUB 6.3
diisobutyl phthalate 6.2
Diallyl disulfide 6.2
Diallyl disulfide 6.2
dicyclohexyl phthalate 6.2
Tetramethylpyrazine 6.2
TCTP 6.2
PMP 6.1
3-Deazaneplanocin 6.1
DDC 6.1
suberic acid 6.1
Aloe-emodin 6.1
Laminarin 6.1
DDC 6.1
NIX 6.1
Sulindac 6.1
HCP 6.1
Fucoidan 6.0
Chelerythrine 6.0
Chelerythrine 6.0
Embelin 6.0
MME 6.0
Emodin 6.0
DMP 6.0
Eugenol 5.9
Eugenol 5.9
DMP 5.9
Galangin 5.9
HN3 5.9
Antimycin 5.9
DMP 5.9
Piperidine 5.9
Norharman 5.9
benzo[c]phenanthridine 5.8
6-Thioguanine 5.8
6-Mercaptopurine 5.8
HCP 5.8
Doxycycline 5.8
Esculetin 5.6
DEP 5.6
benzenesulfonyl fluoride 5.6
Elastin 5.6
Bufalin 5.6
Hesperidin 5.6
TMG 5.6
Baicalein 5.6
EOC 5.6
Acteoside 5.6
Naringin 5.5
HMBA 5.5
Isoliquiritigenin 5.5
2-Methoxyestradiol 5.5
Piperine 5.5
Collagen 5.5
more...