Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.23 (
MMP
)
4,246
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Carrier-mediated prostaglandin transport has been postulated to occur in many tissues. On the basis of sequence homology, the protein of unknown function encoded by the rat
matrin
F/G complementary DNA was predicted to be an organic anion transporter. Expression of the
matrin
F/G complementary DNA in HeLa cells or Xenopus oocytes conferred the property of specific transport of prostaglandins. The tissue distribution of
matrin
F/G messenger RNA and the sensitivity of
matrin
F/G-induced prostaglandin transport to inhibitors were similar to those of endogenous prostaglandin transport. The protein encoded by the
matrin
F/G complementary DNA is thus preferably called
PGT
because it is likely to function as a prostaglandin transporter.
...
PMID:Identification and characterization of a prostaglandin transporter. 775 69
