Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.24.17 (MMP-3)
3,419 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MMP-3 2358 stromelysin 1277 MMP-1 974 matrix metalloproteinase 818 MMP-9 771 MMP-2 693 collagen 621 collagenase 551 EPA 464 MMP-13 461 metalloproteinase 436 TIMP-2 279 IL-6 276 matrix metalloproteinase 2 249 Mol 233 cytokine 231 Sep 221 TNF 216 MMP 207 aggrecan 191 tissue inhibitor of metalloproteinases 185 matrix metalloproteinase 3 183 tumor necrosis factor 172 proteoglycan 163 fibronectin 160 MMP-7 144 MMP-8 138 MT1-MMP 132 IL-1 120 MMP-10 112 AP-1 112 IL-8 111 matrilysin 105 TIMP 101 p38 100 type II collagen 97 COX-2 94 ADAMTS-5 91 MMP-12 90 TIMP-3 89 urokinase-type plasminogen activator 89 MMP9 88 inducible nitric oxide synthase 84 type I collagen 83 TNF-alpha 72 MAPK 71 c-fos 69 p65 69 casein 63 elastin 61 PLA 61 ADAMTS-4 61 epidermal growth factor 59 ERK1 58 plasminogen 58 lipopolysaccharide 57 JNK 56 metalloprotease 56 MMP3 55 interleukin-6 54 IL-10 54 TGF-beta 53 c-Jun 51 vascular endothelial growth factor 50 cyclooxygenase-2 49 ERK 49 IL-1 beta 47 collagenase-3 47 thrombospondin 47 MMP-11 42 tumor necrosis factor alpha 40 extracellular signal-regulated kinase 38 p53 38 mitogen-activated protein 38 ras 37 IL-17 36 caspase-3 35 SDS 35 matrix protein 34 plasminogen activator inhibitor-1 33 more...

Disease tumor 362 osteoarthritis 356 cancer 338 rheumatoid arthritis 266 arthritis 197 tumor progression 94 atherosclerosis 71 carcinoma 70 metastases 59 breast cancer 56 plaque 45 disc degeneration 43 tumor growth 41 squamous cell carcinoma 38 synovitis 37 carcinogenesis 37 periodontitis 36 SDS 35 tumorigenesis 32 melanoma 31 stroke 30 diabetes 30 ischemia 29 arthropathy 28 adenocarcinoma 25 multiple sclerosis 25 Alzheimer's disease 22 prostate cancer 22 autoimmune disease 21 hepatocellular carcinoma 21 periodontal disease 21 myocardial infarction 20 degenerative disc disease 20 coronary artery disease 19 uterus 19 hypertension 19 MCF 17 COL2A1 17 lung cancer 17 chondrosarcoma 16 GSH 15 osteosarcoma 15 skin cancer 15 Blocking 15 colorectal cancer 15 degenerative disease 15 heart failure 14 inflammatory bowel disease 14 asthma 14 obesity 14 glioma 14 fibrosarcoma 14 liver fibrosis 13 cornea 12 lung carcinoma 12 endometriosis 12 pheochromocytoma 12 infectious diseases 12 Crohn's disease 12 colon cancer 11 Infection 11 cerebral ischemia 11 premature aging 10 inflammatory joint disease 10 PCC 10 colitis 10 CTX 10 cardiovascular disease 10 tumor angiogenesis 9 Parkinson's disease 9 mammary tumor 9 systemic lupus erythematosus 9 cirrhosis 9 ulcerative colitis 9 HIV 9 glaucoma 9 abdominal aortic aneurysm 8 CCL 8 acute myocardial infarction 8 papilloma 8 more...

Symptom pain 40 back pain 10 thinning 10 low back pain 10 angina 8 arthralgia 8 skin damage 7 erythema 7 swollen joints 5 collapse 4 weakness 4 headache 3 knee pain 3 functional recovery 3 dry eye 2 respiratory distress 2 disturbed balance 2 anesthesia 2 Quadriceps weakness 1 chronic back pain 1 neurological disability 1 acidity 1 cachexia 1 anorexia 1 stigma 1 discomfort 1 bitter taste 1 dry skin 1 distraction 1 analgesia 1 overweight 1 shoulder pain 1 DNA marker 1 starvation 1 myalgia 1 spasm 1 cerebellar ataxia 1 seizures 1 abdominal pain 1 hyperoxia 1 discomfort 1 Wind 1 Trembling 1 cough 1 hypothermia 1

Drug Dermatol 59 Gelatin 36 ROS 22 IFN-gamma 20 uPA 20 IL-2 15 Asn 15 CSF 15 MAP 15 ETS 12 lysine 11 Gel 10 Cardiovasc 10 CTX 10 CTX 10 CTX 10 Monit 8 CCL 8 Batimastat 8 Batimastat 8 Retinoic acid 7 Paraffin 6 ABC 6 ROC 6 Doxycycline 5 Indomethacin 4 Marimastat 4 Nephron 4 CIA 4 ZnCl2 3 Infliximab 3 Nephron 3 MRC 3 PTH 3 IL-1ra 3 G418 3 CaCl2 3 CaCl2 3 ZnCl2 3 Infliximab 3 CaCl2 3 Nimesulide 2 Tiaprofenic acid 2 Forskolin 2 nitroglycerin 2 Emodin 2 Bevacizumab 2 vitamin E 2 Prinomastat 2 ascorbate 2 Emodin 2 ALA 2 Asthma 2 -deoxyadenosine 2 Norplant 2 TEL 2 lactose 2 Dial 2 Simvastatin 2 IL-11 2 Adalimumab 2 Norplant 2 Aloe 2 Aprotinin 1 Fluorescein 1 ETA 1 ENT 1 Gemfibrozil 1 Leaf 1 THF 1 Abatacept 1 DNase I 1 SrCl2 1 Monensin 1 Gly-Tyr-Gly 1 Vitamin A 1 Portal 1 PNT 1 AGG 1 Finasteride 1 more...

Enzyme MMP-3 3419 collagenase 1389 MMP 302 matrix metalloproteinase 2 227 mitogen-activated protein kinase 224 interstitial collagenase 201 matrix metalloproteinase 9 167 urokinase-type plasminogen activator 115 plasmin 93 trypsin 78 ERK 72 protein kinase C 52 elastase 42 tissue plasminogen activator 36 neutrophil elastase 33 protein kinase 33 luciferase 30 cathepsin G 30 neutrophil collagenase 30 MEK 29 alkaline phosphatase 29 caspase-3 29 catalase 28 focal adhesion kinase 27 superoxide dismutase 26 stromelysin-3 25 reverse transcriptase 23 chloramphenicol acetyltransferase 19 chymotrypsin 19 thrombin 18 peroxidase 17 macrophage elastase 17 thermolysin 16 CD10 16 cathepsin B 15 kallikrein 12 phospholipase A2 11 collagenase 3 11 matrix metalloproteinase 10 11 transcriptase 10 RNA polymerase 10 tryptase 10 TACE 10 phospholipase C 10 glyceraldehyde-3-phosphate dehydrogenase 10 AMP-activated protein kinase 9 furin 9 glutathione peroxidase 9 MAP 9 cathepsin L 8 phosphatidylinositol 3-kinase 8 MIP 8 caspase-9 8 cathepsin D 7 caspase-1 7 pepsin 7 NO synthase 7 papain 7 astacin 7 thymidine kinase 6 glyceraldehyde-3-phosphate dehydrogenase 6 glyceraldehyde-3-phosphate dehydrogenase 6 IKK 6 RNase 6 hyaluronidase 6 RNase 6 proteasome 5 heme oxygenase 5 glyceraldehyde-3-phosphate dehydrogenase 5 PARP 5 aggrecanase-1 5 glyceraldehyde-3-phosphate dehydrogenase 5 lactate dehydrogenase 5 beta-glucuronidase 5 chymase 5 ornithine decarboxylase 5 caspase-8 5 AMPK 4 lipoprotein lipase 4 lysyl oxidase 4 more...

Compound Dec 278 TNF 216 DNA 167 Clin 150 acetate 150 zinc 136 oxygen 85 serine 79 nitric oxide 78 calcium 65 leucine 60 sulfate 53 Collagenase 51 alanine 51 arginine 50 PGE2 48 PGE 48 Gly 45 Collagen 45 sodium 41 NH2 41 EDTA 40 EDTA 40 SDS 39 cysteine 37 lysine 36 retinoic acid 36 tyrosine 34 water 34 phosphate 30 glucose 27 Phe 26 MDA 26 hyaluronic acid 26 hydrogen 25 Asp 25 ASA 23 MTT 23 threonine 19 methionine 18 Ile 18 MEK 18 GSH 16 TPA 16 CAT 16 CAT 16 CAT 16 GSH 16 TPA 16 Cardiol 15 Curcumin 13 cAMP 13 His 13 THP 13 THP 13 PMA 12 AMP 12 Plasmin 12 salt 12 Safranin O 12 bromide 11 nitrogen 11 PMA 11 MAP 11 galactose 11 Dexamethasone 11 proline 10 TACE 10 urea 10 CCP 10 CTX 10 tryptophan 9 N-acetylcysteine 9 tryptophan 9 COS 9 tryptophan 9 tryptophan 9 Cereb 9 DBA 9 silver 8 more...

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