Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.17 (MMP-3)
3,419 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MMP-3 2358
stromelysin 1277
MMP-1 974
matrix metalloproteinase 818
MMP-9 771
MMP-2 693
collagen 621
collagenase 551
EPA 464
MMP-13 461
metalloproteinase 436
TIMP-2 279
IL-6 276
matrix metalloproteinase 2 249
Mol 233
cytokine 231
Sep 221
TNF 216
MMP 207
aggrecan 191
tissue inhibitor of metalloproteinases 185
matrix metalloproteinase 3 183
tumor necrosis factor 172
proteoglycan 163
fibronectin 160
MMP-7 144
MMP-8 138
MT1-MMP 132
IL-1 120
AP-1 112
MMP-10 112
IL-8 111
matrilysin 105
TIMP 101
p38 100
type II collagen 97
COX-2 94
ADAMTS-5 91
MMP-12 90
urokinase-type plasminogen activator 89
more...
Disease
tumor 362
osteoarthritis 356
cancer 338
rheumatoid arthritis 266
arthritis 197
tumor progression 94
atherosclerosis 71
carcinoma 70
metastases 59
breast cancer 56
plaque 45
disc degeneration 43
tumor growth 41
squamous cell carcinoma 38
synovitis 37
carcinogenesis 37
periodontitis 36
SDS 35
tumorigenesis 32
melanoma 31
diabetes 30
stroke 30
ischemia 29
arthropathy 28
adenocarcinoma 25
multiple sclerosis 25
Alzheimer's disease 22
prostate cancer 22
periodontal disease 21
autoimmune disease 21
hepatocellular carcinoma 21
myocardial infarction 20
degenerative disc disease 20
coronary artery disease 19
uterus 19
hypertension 19
COL2A1 17
MCF 17
lung cancer 17
chondrosarcoma 16
more...
Symptom
pain 40
back pain 10
thinning 10
low back pain 10
angina 8
arthralgia 8
skin damage 7
erythema 7
swollen joints 5
weakness 4
collapse 4
headache 3
functional recovery 3
knee pain 3
dry eye 2
respiratory distress 2
disturbed balance 2
anesthesia 2
Quadriceps weakness 1
chronic back pain 1
neurological disability 1
acidity 1
cachexia 1
anorexia 1
spasm 1
myalgia 1
seizures 1
discomfort 1
overweight 1
shoulder pain 1
DNA marker 1
starvation 1
abdominal pain 1
hyperoxia 1
discomfort 1
dry skin 1
Wind 1
Trembling 1
cough 1
hypothermia 1
more...
Drug
Dermatol 59
Gelatin 36
ROS 22
uPA 20
IFN-gamma 20
IL-2 15
MAP 15
Asn 15
CSF 15
ETS 12
lysine 11
CTX 10
Gel 10
CTX 10
CTX 10
Cardiovasc 10
Batimastat 8
Batimastat 8
Monit 8
CCL 8
Retinoic acid 7
Paraffin 6
ABC 6
ROC 6
Doxycycline 5
CIA 4
Indomethacin 4
Marimastat 4
Nephron 4
IL-1ra 3
Infliximab 3
PTH 3
Infliximab 3
ZnCl2 3
ZnCl2 3
G418 3
CaCl2 3
Nephron 3
CaCl2 3
CaCl2 3
more...
Enzyme
MMP-3 3419
collagenase 1389
MMP 302
matrix metalloproteinase 2 227
mitogen-activated protein kinase 224
interstitial collagenase 201
matrix metalloproteinase 9 167
urokinase-type plasminogen activator 115
plasmin 93
trypsin 78
ERK 72
protein kinase C 52
elastase 42
tissue plasminogen activator 36
neutrophil elastase 33
protein kinase 33
luciferase 30
neutrophil collagenase 30
cathepsin G 30
alkaline phosphatase 29
MEK 29
caspase-3 29
catalase 28
focal adhesion kinase 27
superoxide dismutase 26
stromelysin-3 25
reverse transcriptase 23
chloramphenicol acetyltransferase 19
chymotrypsin 19
thrombin 18
macrophage elastase 17
peroxidase 17
CD10 16
thermolysin 16
cathepsin B 15
kallikrein 12
matrix metalloproteinase 10 11
phospholipase A2 11
collagenase 3 11
transcriptase 10
more...
Compound
Dec 278
TNF 216
DNA 167
acetate 150
Clin 150
zinc 136
oxygen 85
serine 79
nitric oxide 78
calcium 65
leucine 60
sulfate 53
Collagenase 51
alanine 51
arginine 50
PGE2 48
PGE 48
Collagen 45
Gly 45
sodium 41
NH2 41
EDTA 40
EDTA 40
SDS 39
cysteine 37
retinoic acid 36
lysine 36
tyrosine 34
water 34
phosphate 30
glucose 27
MDA 26
Phe 26
hyaluronic acid 26
Asp 25
hydrogen 25
MTT 23
ASA 23
threonine 19
MEK 18
more...