Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.17 (
MMP-3
)
3,419
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MMP-3
2358
stromelysin
1277
MMP-1
974
matrix metalloproteinase
818
MMP-9
771
MMP-2
693
collagen
621
collagenase
551
EPA
464
MMP-13
461
metalloproteinase
436
TIMP-2
279
IL-6
276
matrix metalloproteinase 2
249
Mol
233
cytokine
231
Sep
221
TNF
216
MMP
207
aggrecan
191
more...
Disease
tumor
362
osteoarthritis
356
cancer
338
rheumatoid arthritis
266
arthritis
197
tumor progression
94
atherosclerosis
71
carcinoma
70
metastases
59
breast cancer
56
plaque
45
disc degeneration
43
tumor growth
41
squamous cell carcinoma
38
carcinogenesis
37
synovitis
37
periodontitis
36
SDS
35
tumorigenesis
32
melanoma
31
more...
Symptom
pain
40
thinning
10
back pain
10
low back pain
10
angina
8
arthralgia
8
erythema
7
skin damage
7
swollen joints
5
weakness
4
collapse
4
knee pain
3
headache
3
functional recovery
3
respiratory distress
2
anesthesia
2
dry eye
2
disturbed balance
2
chronic back pain
1
overweight
1
more...
Drug
Dermatol
59
Gelatin
36
ROS
22
IFN-gamma
20
uPA
20
CSF
15
Asn
15
IL-2
15
MAP
15
ETS
12
lysine
11
Gel
10
Cardiovasc
10
CTX
10
CTX
10
CTX
10
Batimastat
8
CCL
8
Batimastat
8
Monit
8
more...
Enzyme
MMP-3
3419
collagenase
1389
MMP
302
matrix metalloproteinase 2
227
mitogen-activated protein kinase
224
interstitial collagenase
201
matrix metalloproteinase 9
167
urokinase-type plasminogen activator
115
plasmin
93
trypsin
78
ERK
72
protein kinase C
52
elastase
42
tissue plasminogen activator
36
protein kinase
33
neutrophil elastase
33
neutrophil collagenase
30
luciferase
30
cathepsin G
30
caspase-3
29
more...
Compound
Dec
278
TNF
216
DNA
167
acetate
150
Clin
150
zinc
136
oxygen
85
serine
79
nitric oxide
78
calcium
65
leucine
60
sulfate
53
Collagenase
51
alanine
51
arginine
50
PGE2
48
PGE
48
Collagen
45
Gly
45
sodium
41
more...