Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.17 (MMP-3)
 3,419 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ZNF510 13.2
matrix metalloproteinase 3 13.1
MMP-3 13.0
stromelysin 12.7
growth and transformation-dependent protein 12.2
SPBP 11.9
matrix metalloproteinase 10 11.6
MMP-1 11.3
ADAMTS-4 11.2
MMP-10 11.2
MMP-13 11.2
Cas-interacting zinc finger protein 11.2
MMP-11 11.1
MMP-25 11.1
MMP-19 11.0
DC32 10.9
MMP-27 10.9
metalloelastase 10.8
matrilysin 10.7
MT5-MMP 10.7
ADAMTS-5 10.7
MMP-7 10.6
Neurolysin 10.5
PLGL 10.5
UEF 10.5
stromelysin-3 10.5
Metalloelastase 10.4
ADAMTS-8 10.4
tissue inhibitor of metalloproteinases 10.4
MMP-12 10.3
MT4-MMP 10.2
Aggrecanase-1 10.2
TIMP-3 10.2
MMP-8 10.2
TIMP-2 10.2
TIMP 10.2
TIMP-4 10.1
MT2-MMP 10.0
Epilysin 10.0
leukolysin 10.0
MMP-23 10.0
Chondroadherin 10.0
collagenase-3 10.0
MMP-26 10.0
MMP-28 9.9
aggrecanase-1 9.9
ERp60 9.8
ADAMTS15 9.8
E1A-F 9.7
matrix metalloproteinase 1 9.7
Type XIV collagen 9.7
matrix metalloproteinase 2 9.7
MT1-MMP 9.7
TEL-2 9.6
MADA 9.6
transmembrane protease, serine 4 9.5
SFMBT2 9.5
EDA protein 9.5
MMP3 9.5
MMP-2 9.5
MMP-21 9.4
MMP-20 9.4
Insulin-like growth factor-binding protein 5 9.4
LOXL 9.4
DEFA6 9.4
MMP-9 9.3
cartilage intermediate layer protein 9.3
MMP24 9.3
syndecan 3 9.3
endopeptidase-2 9.3
ADAMTS4 9.3
Tissue factor pathway inhibitor-2 9.2
LGMN 9.2
TSR2 9.2
metalloproteinase 9.1
tissue inhibitor of metalloproteinase 1 9.1
ADAM metallopeptidase domain 17 9.0
epilysin 9.0
tissue inhibitor of metalloproteinases-2 9.0
MMP 9.0
CARF 9.0
metalloproteinase 1 9.0
aggrecan 8.9
matrix metalloproteinase 8.9
MMP25 8.9
CIZ 8.8
Tissue inhibitor of metalloproteinase 1 8.8
SPP-1 8.8
PTPRA 8.7
collectin liver 1 8.7
ovostatin 8.7
laminin B2 8.7
Matrix metalloproteinase 1 8.7
retinoid-related orphan receptor gamma 8.7
TIMP metallopeptidase inhibitor 1 8.6
ADAM17 protein 8.6
ADAM-15 8.6
EFEMP2 8.6
MT6-MMP 8.6
EPA 8.6
neurolysin 8.6
collagenase 8.5
SM3 8.5
metalloprotease 1 8.5
osteoactivin 8.5
Friend leukemia virus integration 1 8.5
ZBP-89 8.5
PIAS2 8.4
follistatin-related protein 8.4
extracellular matrix metalloproteinase inducer 8.4
vgf 8.4
RLN2 8.4
FLS 8.4
u-PA 8.4
PROTEIN PHOSPHATASE 8.4
HOXB5 8.4
Metalloproteinase 8.3
CHAD 8.3
SAMD9L 8.3
GRF2 8.3
ITGA8 8.3
IDDM5 8.2
ADAMDEC1 8.2
MT-IG 8.2
scavenger receptor expressed by endothelial cells 8.2
IL-17RE 8.1
Aggrecan 8.1
pre-B-cell colony-enhancing factor 8.1
collectin placenta 1 8.1
ETS-1 8.1
prorelaxin 8.1
class II cytokine receptor 8.0
MNAR 8.0
cyclophilin C 8.0
Matrix metalloproteinase 9 8.0
integrin beta 2 8.0
ADAMTS18 8.0
MAML3 8.0
WAVE3 7.9
CL-K1 7.9
TIMP1 7.9
NGFB 7.9
FGFR3 protein 7.9
cathepsin L2 7.9
link protein 7.9
MEPE 7.9
INOS 7.9
SCG10 7.8
HPT1 7.8
neurofilament light protein 7.8
integrin beta 3 7.8
MMP12 7.8
protein arginine deiminase 7.8
PRP-3 7.7
zinc metalloendopeptidase 7.7
hSef 7.7
restin 7.7
COL2A1 7.7
TSR1 7.7
microfibril-associated glycoprotein 7.7
more...
Disease
Mycoplasma arthritis 11.2
Corticosteroid-induced glaucoma 11.2
Canine elbow dysplasia 10.9
Tumor embolus 10.0
Biliary fibrosis 10.0
anaplastic osteosarcoma 9.4
Cytotoxic edema 9.4
Autoimmune myocarditis 9.3
cervical disc degeneration 9.0
Lumbar disc degeneration 8.9
RS3PE syndrome 8.4
benign proliferative breast disease 8.2
Steinbrocker 8.0
Mandibuloacral dysplasia 7.9
prostate cancer stage 7.9
facet joint degeneration 7.8
disc degeneration 7.7
Takahara 7.7
COL2A1 7.7
Tendinopathy 7.7
EBSS 7.6
degenerative disc disease 7.6
metastatic endometrial cancer 7.5
scleromalacia 7.5
inflammatory joint disease 7.4
Achilles tendinitis 7.4
Acute asthma 7.3
chondrolysis 7.2
Bone marrow edema 7.1
varicose ulcer 7.0
Pulmonary lymphangioleiomyomatosis 6.9
anetoderma 6.9
blepharochalasis 6.8
Neisseria gonorrhoeae infection 6.8
taste disorder 6.8
Peritoneal fibrosis 6.8
menopausal bleeding 6.8
Pseudopregnancy 6.6
osteoarthritis 6.5
Lequesne 6.5
Cardiovascular morbidity 6.5
MDK 6.5
Kashin-Beck disease 6.4
X-linked hydrocephalus 6.4
acroosteolysis 6.3
pulpitis 6.2
Lyme arthritis 6.2
IDD 6.2
bladder neoplasm 6.2
Intrauterine infection 6.2
Epidermolysis bullosa acquisita 6.1
ovarian serous cystadenocarcinoma 6.0
Recessive dystrophic epidermolysis bullosa 6.0
synovitis 6.0
CCL 5.9
Gingival overgrowth 5.9
herniated disc 5.9
PSN 5.9
Cardiac rupture 5.8
Dengue hemorrhagic fever 5.8
osteochondrodysplasia 5.6
MSS 5.6
degenerative disease 5.6
arthritis of the knee 5.6
rheumatoid arthritis 5.5
retrograde menstruation 5.5
Verrucous carcinoma 5.5
osteoblastic osteosarcoma 5.5
Prinzmetal 5.4
Chlamydia pneumoniae infection 5.4
premature aging 5.4
Malignant glioma 5.4
Pseudomonas infection 5.3
scleritis 5.3
Pigmented villonodular synovitis 5.2
Koebner 5.2
Pigmented villonodular synovitis 5.2
Spondyloarthritis 5.1
Tauopathies 5.1
sialidosis 5.1
chondrosarcoma 5.1
arthropathy 5.0
uncomplicated hypertension 4.9
EGC 4.9
Chimera 4.9
orphan disease 4.9
tendinitis 4.9
epithelial tumor 4.9
Candida albicans infection 4.8
malignant state 4.8
metastatic osteosarcoma 4.8
NDI 4.8
enthesopathy 4.8
periodontitis 4.7
pancreatic fibrosis 4.7
cutis laxa 4.7
Cerebral malaria 4.7
arthritis 4.7
progeria 4.7
biventricular failure 4.7
frozen shoulder 4.7
Granuloma 4.7
spondyloarthropathy 4.6
pseudoxanthoma elasticum 4.6
dyschondroplasia 4.6
pseudogout 4.6
Hereditary spastic paraplegia 4.6
Bronchiolitis obliterans 4.5
Renal fibrosis 4.5
entropion 4.5
periodontal disease 4.5
milia 4.5
plexiform neurofibroma 4.5
Schistosoma mansoni infection 4.5
Alport syndrome 4.5
ASM 4.5
tumor progression 4.4
keratoconus 4.4
Headache Disorders 4.4
rheumatic mitral stenosis 4.4
keratocyst 4.4
Esophageal squamous cell carcinoma 4.4
SCP 4.4
MEN 2B 4.4
MPE 4.3
chemical carcinogenesis 4.3
Septic arthritis 4.3
benign nevi 4.3
DSS 4.3
TMJ 4.3
musculoskeletal disease 4.3
EMD 4.3
PTP 4.2
LIP 4.2
Angiosarcoma 4.2
monoarthritis 4.2
fibrocystic disease 4.2
Aortic dissection 4.2
invasive cancer 4.2
ADD 4.2
coxarthrosis 4.2
nephrosis 4.2
lobular carcinoma in situ 4.2
Perthes disease 4.2
status asthmaticus 4.2
Dermal 4.1
EMC 4.1
fibrosarcoma 4.1
comedo 4.1
dermatitis herpetiformis 4.1
SMD 4.1
epidermolysis bullosa 4.1
epicondylitis 4.1
seborrheic keratosis 4.1
HOS 4.1
AGS 4.1
localized scleroderma 4.0
viral meningitis 4.0
keratosis 4.0
SCD 4.0
more...
Symptom
Quadriceps weakness 8.9
Trembling 8.5
swollen joints 6.4
disturbed balance 6.4
skin damage 5.4
chronic back pain 3.6
arthralgia 3.4
neurological disability 3.3
DNA marker 3.3
knee pain 3.3
low back pain 3.2
dry skin 3.2
thinning 3.0
back pain 2.9
dry eye 2.8
bitter taste 2.7
erythema 2.3
Wind 1.8
angina 1.8
shoulder pain 1.7
cerebellar ataxia 1.4
functional recovery 1.1
hyperoxia 0.8
cachexia 0.7
pain 0.5
myalgia 0.5
collapse 0.4
spasm 0.3
distraction -0.0
weakness -0.0
respiratory distress -0.1
stigma -0.5
anorexia -0.6
acidity -0.7
hypothermia -0.9
headache -1.0
discomfort -1.3
cough -1.4
discomfort -1.4
starvation -1.4
overweight -1.5
analgesia -1.6
abdominal pain -1.7
anesthesia -2.6
seizures -3.1
Drug
Tanomastat 13.2
Prinomastat 10.0
Batimastat 9.7
Batimastat 9.7
Trimegestone 9.6
Marimastat 9.0
Pentosan polysulfate sodium 8.9
Avasimibe 8.6
Hirudoid 8.4
Tiaprofenic acid 8.2
Ilomastat 7.9
Gly-Tyr-Gly 7.8
Gelatin 7.6
Butaprost 7.2
Deflazacort 6.8
Bimatoprost 6.7
uPA 6.5
PNT 6.1
Nimesulide 6.0
CCL 5.8
SrCl2 5.8
BOTOX 5.8
Bexarotene 5.8
Tibolone 5.7
SrCl2 5.7
CIA 5.6
Abatacept 5.6
NOV 5.5
Doxycycline 5.4
ETS 5.4
Argatroban 5.3
Emodin 5.3
Arthrex 5.2
Adalimumab 5.1
Emodin 5.0
Myricetin 4.9
Gemfibrozil 4.8
Paraffin 4.7
Infliximab 4.6
Infliximab 4.6
SMP 4.6
TEL 4.6
Dextrose 4.6
Norplant 4.5
Cilostazol 4.5
Tocilizumab 4.5
ZnCl2 4.4
Finasteride 4.4
ZnCl2 4.4
Ramipril 4.4
IL-1ra 4.4
CVA 4.3
KGF 4.3
Retinoic acid 4.3
IL-11 4.1
CTX 4.0
CTX 4.0
Aloe 3.9
Oseltamivir 3.9
Urokinase 3.9
Budesonide 3.9
Pilocarpine 3.9
PDL 3.8
Raloxifene 3.7
G418 3.6
Asn 3.6
AGG 3.6
Simvastatin 3.5
ROS 3.4
Norplant 3.4
Bevacizumab 3.4
DEX 3.3
Aprotinin 3.3
Monensin 3.3
Isoniazid 3.3
Prednisone 3.2
CTX 3.2
-deoxyadenosine 3.2
MAP 3.2
FLP 3.1
Etoposide 3.0
MRC 3.0
DPA 2.9
ROC 2.9
Forskolin 2.8
BLM 2.8
ALA 2.7
Glycyrrhiza 2.7
IFN-gamma 2.7
ABC 2.7
Gel 2.6
Indomethacin 2.6
Activin 2.5
IL-2 2.3
ADR 2.2
Frontal 2.2
CSF 2.2
CaCl2 2.1
CaCl2 2.1
CaCl2 2.1
PTH 2.0
Fragment 2.0
Silica 2.0
ETA 1.7
Rituximab 1.7
Vitamin A 1.6
Vitamin E 1.5
Fluorescein 1.3
Nephron 1.2
Portal 1.1
Monit 1.1
nitroglycerin 1.1
Dermatol 1.1
Nephron 1.1
Angiotensin II 0.9
lysine 0.8
Glutathione 0.8
ICI 0.8
Histamine 0.7
EE2 0.3
THF 0.2
DNase I 0.2
lactose 0.2
ENT 0.1
vitamin E 0.1
ascorbate -0.3
Asthma -0.5
Dial -0.7
Cardiovasc -1.1
caffeine -1.2
Leaf -1.2
Enzyme
MMP-3 13.2
matrix metalloproteinase 10 11.5
interstitial collagenase 11.0
stromelysin-3 10.8
collagenase 3 10.7
neutrophil collagenase 10.5
deuterolysin 10.2
macrophage elastase 10.1
matrix metalloproteinase 2 9.8
aggrecanase-1 9.6
collagenase 9.5
matrix metalloproteinase 9 9.5
MMP 9.4
matrilysin-2 8.9
neurolysin 8.2
astacin 8.0
adamalysin 7.9
cathepsin G 7.3
carboxyl proteinase 7.0
TACE 6.9
heparitinase I 6.8
urokinase-type plasminogen activator 6.6
phosphatidylinositol phospholipase C 6.6
plasmin 6.6
Lys-gingipain 6.4
thermolysin 6.3
neutrophil elastase 6.2
hatching enzyme 6.2
hepsin 6.0
hepsin 6.0
NMT 5.8
chondroitin ABC lyase 5.7
caspase-10 5.7
TSR 5.7
KLK7 5.7
meprin 5.7
caspase-10 5.6
HCS 5.5
endoproteinase Glu-C 5.5
elastase 5.4
inositol 3-kinase 5.3
cathepsin L 5.2
endo-beta-galactosidase 5.2
chymase 5.1
chloramphenicol acetyltransferase 5.1
cathepsin B 5.1
tryptase 5.1
biliverdin reductase 5.1
TSP-1 5.0
thymidylate kinase 5.0
lysyl oxidase 4.9
tissue plasminogen activator 4.9
enterokinase 4.8
acrosin 4.8
SMP 4.8
type III procollagen 4.7
caspase-11 4.7
caspase-11 4.7
furin 4.7
insulin-degrading enzyme 4.7
nicotinamide phosphoribosyltransferase 4.7
matriptase 4.6
cathepsin C 4.6
galactocerebrosidase 4.5
mitogen-activated protein kinase 4.4
PHD 4.4
SCP 4.4
indoleamine 2,3-dioxygenase 4.3
carboxypeptidase A 4.2
prolidase 4.2
matriptase 4.2
kallikrein 4.2
thymidine phosphorylase 4.2
trypsin 4.1
HK2 4.1
PI-PLC 4.0
chymotrypsin 4.0
cathepsin D 4.0
prolyl hydroxylase 3.9
CD10 3.9
MIP 3.9
cathepsin K 3.9
MEK 3.9
tissue kallikrein 3.9
porphobilinogen deaminase 3.9
glyceraldehyde-3-phosphate dehydrogenase 3.8
chondroitinase 3.8
mu-calpain 3.8
cholesterol acyltransferase 3.8
E-2 3.7
chondroitinase 3.7
MAT 3.6
peptidyl-prolyl cis-trans isomerase 3.6
glyceraldehyde-3-phosphate dehydrogenase 3.6
prolyl endopeptidase 3.6
m-calpain 3.5
IKK 3.5
MAP 3.5
heme oxygenase 3.5
phosphoglucose isomerase 3.5
paraoxonase 3.4
MAT 3.4
glyceraldehyde-3-phosphate dehydrogenase 3.4
glyceraldehyde-3-phosphate dehydrogenase 3.4
caspase-1 3.4
IMP dehydrogenase 3.4
prostaglandin synthetase 3.3
glyceraldehyde-3-phosphate dehydrogenase 3.3
caspase-9 3.3
papain 3.3
cholesterol esterase 3.3
protein kinase C 3.3
transcriptase 3.3
ADP-ribosyltransferase 3.2
hyaluronidase 3.2
paraoxonase 3.2
ADP-ribosyltransferase 3.1
STR 3.1
15-lipoxygenase 3.0
TSA 3.0
pepsin 2.9
caspase-3 2.9
thymidine kinase 2.9
heparinase 2.9
ornithine decarboxylase 2.9
luciferase 2.9
carboxypeptidase Y 2.8
phospholipase A2 2.8
ERK 2.8
caspase-8 2.8
reverse transcriptase 2.8
phosphatidylinositol 3-kinase 2.8
AMP-activated protein kinase 2.7
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.7
phosphoinositide 3-kinase 2.7
PNGase F 2.6
hyaluronidase 2.6
beta-glucuronidase 2.6
AMPK 2.6
focal adhesion kinase 2.5
alkaline phosphatase 2.5
dipeptidyl peptidase IV 2.5
lipoprotein lipase 2.4
NOS 2.4
phospholipase C 2.3
thrombin 2.3
MEKK1 2.3
DCF 2.2
catalase 2.2
HIV-1 protease 2.1
chitinase 2.1
hormone-sensitive lipase 2.1
phosphoglycerate kinase 2.1
CAD 2.1
CAD 2.1
PDK1 2.1
NO synthase 2.0
superoxide dismutase 2.0
CAD 2.0
transglutaminase 1.9
more...
Compound
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 12.2
C15H26O 11.6
C15H26O 11.6
C15H26O 11.6
alpha-Eudesmol 11.2
Himachalol 11.2
C15H26O 11.2
C15H26O 11.2
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol 10.9
C20H24O6 10.9
C6H12N2O 10.9
Globulol 10.9
C15H26O 10.9
C15H26O 10.9
C15H26O2 10.6
Hydrangenol 10.4
Hinesol 10.4
Guaiol 10.4
Chamazulene 9.9
Alizarin complexone 9.9
Monotropein 9.7
4000 M 9.5
2,4-pyrimidinediamine 9.5
Tricetin 9.5
Azocoll 9.4
beta-Eudesmol 9.1
Cedrol 8.9
Isofraxidin 8.9
Collagenase 8.9
Stachydrine 8.7
C15H24 8.6
Eudesmol 8.3
Sinapic acid 8.2
Fangchinoline 8.2
Tectorigenin 8.2
Anserine 8.2
Swertiamarin 8.2
2,3-hexanedione 8.1
Patchouli alcohol 8.1
Sclareol 7.9
Stachydrine 7.9
Aucubin 7.8
Laminariaceae 7.8
Theaflavin 7.7
ETN 7.6
Myricitrin 7.5
Safranin O 7.5
Tricin 7.5
Decursin 7.5
Scoparone 7.4
Mycosporine 7.4
Sesamin 7.3
Safranin O 7.2
Acacetin 7.2
Plasmin 7.2
Loganin 7.1
Oleuropein 7.1
Nerolidol 6.9
Zingerone 6.9
Nerolidol 6.9
Pinocembrin 6.9
Butein 6.9
TACE 6.8
Myrcene 6.8
Pyridinoline 6.8
Diosmin 6.7
Nobiletin 6.7
Diethyl pyrocarbonate 6.6
Stanozolol 6.6
Vitexin 6.6
succinamide 6.6
Tyrosol 6.6
Stanozolol 6.5
uroporphyrin I 6.5
Stanozolol 6.5
Wogonin 6.4
Matrine 6.3
Matrine 6.3
Matrine 6.3
Mangostin 6.2
Fisetin 6.2
Formononetin 6.1
SAN 6.1
Evodiamine 6.1
Glucosamine 6.1
PNT 6.1
Polydatin 6.1
A101 6.1
Dimethyl fumarate 6.0
Iodoacetamide 6.0
Biochanin A 6.0
butyramide 6.0
Montelukast 6.0
Evodiamine 6.0
Phloretin 6.0
Cordycepin 6.0
Cordycepin 6.0
Cordycepin 5.9
Bufalin 5.9
Crocin 5.9
Carnosic acid 5.9
TTNPB 5.9
CCP 5.8
Celastrol 5.8
Isoliquiritigenin 5.8
Piperine 5.8
Paeonol 5.8
Nandrolone 5.8
Glycyrrhetinic acid 5.8
Alendronate 5.7
PGE 5.7
Pterostilbene 5.7
Biliverdin 5.6
Alendronate 5.6
HAQ 5.6
Collagen 5.5
Genipin 5.5
Pyrogallol 5.5
keratan sulfate 5.5
Mithramycin 5.5
Diosgenin 5.5
Glycyrrhetinic acid 5.5
Doxycycline 5.4
Farnesol 5.4
Diallyl 5.4
celastrol 5.4
SP-1 5.4
Argatroban 5.4
Plumbagin 5.4
Elastin 5.3
Lipoxin A4 5.3
hexanoic acid 5.3
Emodin 5.3
Cys-Gly 5.3
Naringin 5.3
methanesulfonamide 5.3
1H-pyrrole 5.3
methanesulfonamide 5.3
1H-pyrrole 5.2
D-glucosamine 5.2
4-phenyl-1,2,3,6-tetrahydropyridine 5.2
hexanoic acid 5.2
Shikonin 5.2
hexuronic acid 5.1
Rhein 5.1
nonanoic acid 5.1
nonanoic acid 5.1
hexuronic acid 5.1
hexuronic acid 5.1
nonanoic acid 5.1
hexuronic acid 5.1
Chondroitin sulfate 5.1
TNF 5.0
more...