Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.11 (CD10)
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Human Gene/Protein
Membrane metallo-endopeptidase 11.7
RCE1 protein 11.7
MLL-ACTN4 11.7
Endopeptidase-2 11.7
hNRD2 11.7
NEP 11.7
CD10 11.7
endopeptidase-2 11.3
neutral endopeptidase 11.3
MME protein 11.1
Kell blood group protein 11.1
Neutral endopeptidase 10.9
GCET1 10.8
MRPL32 10.7
MLL/AF4 fusion protein 10.7
TFG-NR4A3 fusion 10.7
alpha-methyl-acyl-CoA racemase 10.7
MRPL52 10.7
MUM1 10.6
MUM-1 10.6
NEP2 10.5
MEF2B protein 10.1
SYDE2 10.1
MLL-TET1 10.1
ECE-2 10.1
Type II integral membrane protein 10.1
lipocalin 9 10.1
HSM-2 10.1
MRPL49 10.1
Rho guanine nucleotide exchange factor 7 10.1
IRX-1 10.1
CDC42EP5 10.1
Bcl-6 10.1
opiorphin 10.0
zinc metalloendopeptidase 9.9
E2A/PBX1 fusion 9.9
metalloendopeptidase 9.9
ECEL1 9.8
ECE-1 9.8
TCRgamma alternate reading frame protein 9.7
transforming growth factor alpha precursor 9.7
Opiorphin 9.7
Kell protein 9.7
membrane-bound aminopeptidase P 9.7
GCET2 9.6
Neurolysin 9.6
insulysin 9.5
HGAL 9.5
neurolysin 9.5
BCL-6 9.4
OSGEPL1 9.3
centerin 9.3
dimethyladenosine transferase 9.3
BUD32 9.3
cysteine endopeptidase 9.3
Ksp-cadherin 9.3
CD349 9.3
hGAL 9.3
DF4 9.2
PHEX 9.2
zinc metallopeptidase 9.2
VIL 9.2
AMACR 9.2
Na,K-ATPase gamma subunit 9.1
MLL/AF4 fusion 9.1
taspase 1 9.1
calveolin 9.1
FAM22A 9.1
KNP1 9.1
MRPL51 9.1
BCL6 9.0
insulin-degrading enzyme 9.0
kininase I 9.0
N-arginine dibasic convertase 9.0
NRDC 9.0
carboxypeptidase N 8.9
CD7 8.9
PAX-5 8.9
CD79a 8.9
TCFL5 8.9
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Disease
leptospirosis kidney 11.7
Parasympathetic paraganglioma 11.7
pediatric acute megakaryocytic leukemia 10.7
Giant solitary trichoepithelioma 10.7
Common acute lymphoblastic leukemia 10.6
Mantle zone lymphoma 10.1
MMEP 9.9
CB/CC 9.8
Acute leukemia of ambiguous lineage 9.7
Atypical polypoid adenomyoma 9.4
PAPB 9.3
FAB L1 9.3
bladder papillomata 9.1
Metanephric adenofibroma 9.1
WFS2 9.1
Intestinal nematode infection 9.1
Large cell calcifying Sertoli cell tumor 9.1
Refractory heart failure 9.1
Centroblastic 9.0
Precursor B-cell lymphoblastic lymphoma 8.9
Spontaneous rupture of spleen 8.9
Central nervous system leukemia 8.7
Cellular neurothekeoma 8.7
Hodgkin's disease with lymphocytic predominance 8.7
Atypical fibroxanthoma 8.6
angioimmunoblastic T-cell lymphoma 8.5
Primary cutaneous marginal zone B-cell lymphoma 8.5
Papillary renal cell carcinoma 8.5
Cystic mesothelioma 8.5
c-ALL 8.5
Primary cutaneous B-cell lymphoma 8.4
follicular small cleaved cell lymphoma 8.4
stage IV non-Hodgkin's lymphoma 8.3
endometrial adenoacanthoma 8.3
Trichoepithelioma 8.3
Adenosarcoma 8.3
GCB-DLBCL 8.3
Sporadic cerebral amyloid angiopathy 8.2
Cutaneous endometriosis 8.1
Egg drop syndrome 8.0
Mesonephric adenocarcinoma 8.0
Distal arthrogryposis 7.9
Autosomal recessive hypophosphatemic rickets 7.9
FAB L2 7.9
partial trisomy 11q 7.8
Ossifying fibromyxoid tumor 7.8
Acute mucositis 7.8
trisomy 12q 7.8
Hidradenomas 7.8
Primary mediastinal large B-cell lymphoma 7.7
Nephrogenic adenoma 7.7
Burkitt-like lymphoma 7.7
Renal oncocytoma 7.7
Undifferentiated sarcoma 7.7
Intracranial meningioma 7.7
Lymphoblastic lymphoma 7.6
female sexual arousal disorder 7.6
marginal zone lymphoma 7.6
Squamous cell carcinoma in situ 7.6
B-cell neoplasm 7.6
Abdominal lymphadenopathy 7.6
Diffuse large B-cell lymphoma 7.6
splenic marginal zone lymphoma 7.6
Plasmablastic lymphoma 7.5
fibromyxoma 7.5
endometrial stromal sarcoma 7.5
adult APL 7.5
Immunoblastic 7.5
acute undifferentiated leukemia 7.4
B-ALL 7.4
follicular lymphoma 7.4
Cystitis glandularis 7.4
uterine neoplasm 7.3
Basaloid carcinoma 7.3
Splenic marginal zone lymphoma 7.3
HYP 7.3
nodal marginal zone B-cell lymphoma 7.3
Solid pseudopapillary tumor 7.3
Childhood Leukemia 7.3
FRA11B 7.3
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Symptom
Increased skin sensitivity 11.7
Rebound tenderness 8.9
Mucosal hyperplasia 7.4
Skin thickening 7.3
McBurney's point 6.9
epigastric distress 6.1
staggering gait 5.5
Inflammatory pain 5.4
lumbar back pain 5.2
generalized abdominal pain 5.1
abdominal fullness 5.0
splenomegaly 4.7
hepatosplenomegaly 4.6
non-productive cough 4.5
night sweats 4.2
precordial pain 4.2
hypalgesia 4.2
peri-menopausal 4.2
jaw pain 4.2
Neurologic symptoms 4.1
labored breathing 3.9
anal pain 3.8
postnasal drip 3.7
body pain 3.6
abdominal discomfort 3.5
hepatomegaly 3.5
testicular pain 3.2
bladder pain 3.1
pallor 3.0
epigastric pain 2.9
memory loss 2.8
Spots 2.8
bone pain 2.6
POA 2.6
Decreased activity 2.6
swollen joints 2.6
flank pain 2.6
rhinorrhea 2.5
abdominal pain 2.5
dysuria 2.4
acute abdominal pain 2.3
cough 2.3
pelvic pain 2.3
leg pain 2.3
CSR 2.2
clonus 2.1
polyuria 2.1
sciatica 2.1
shortness of breath 1.9
hip pain 1.9
Stiffness 1.7
HSA 1.7
chronic cough 1.7
fever of unknown origin 1.6
heartburn 1.6
emaciation 1.6
muscle rigidity 1.6
back pain 1.6
urinary frequency 1.5
hypoproteinemia 1.5
nasal congestion 1.5
analgesia 1.5
dental pain 1.4
anorexia 1.4
constipation 1.3
tonic-clonic seizure 1.3
asthenia 1.3
nasal discharge 1.3
paraparesis 1.2
sore throat 1.2
shoulder pain 1.2
bitter taste 1.2
dyspnea 1.1
dizziness 1.0
torticollis 1.0
exertional dyspnea 0.9
neuralgia 0.9
arthralgia 0.9
oliguria 0.8
diarrhea 0.8
more...
Drug
Candoxatrilat 11.6
Candoxatril 11.5
Candoxatril 11.5
Ecadotril 11.3
Omapatrilat 11.3
Phosphoramidon 10.5
Lysostaphin 9.6
Carbocysteine 8.1
Z-Pro-Prolinal 8.0
Bestatin 7.7
C.M.C. 7.7
BoNT/A 7.7
Enalaprilat 7.4
Enalaprilat 7.4
Gly-Tyr-Gly 7.3
Nesiritide 7.3
Sodium metabisulfite 7.2
Bindarit 7.1
Xyrem 6.8
Pepstatin 6.7
CDX 6.5
CA-074 6.4
Valsartan 6.4
CDX 6.0
Aluminum chloride 5.9
PBZ 5.9
TEL 5.8
Oxaprozin 5.7
Nafamostat mesilate 5.7
PNT 5.6
Captopril 5.5
DFP 5.5
Perindopril 5.3
AMC 5.2
Polydioxanone 5.1
Papain 4.9
PE2 4.9
Poudre 4.8
Paraffin 4.7
Aliskiren 4.6
Lactase 4.5
Pyridoxal phosphate 4.5
Arimidex 4.5
Rebamipide 4.4
Rasagiline 4.4
Swainsonine 4.3
anti-CD33 4.3
BOTOX 4.2
Fenoldopam 4.1
Nedocromil sodium 4.1
ETA 4.0
R-gene 4.0
BLyS 4.0
Idarubicin 4.0
AraC 3.9
Hypaque 3.9
ARA-C 3.8
Pirfenidone 3.8
Escitalopram 3.7
Hypaque 3.7
Asn 3.7
Asparaginase 3.7
Oxacillin 3.7
Rituximab 3.6
Luteinizing 3.6
ZnCl2 3.6
ZnCl2 3.6
Nebivolol 3.6
Atropine 3.3
L-tyrosine 3.3
CAM 3.2
Mycophenolic acid 3.2
Gleevec 3.2
Fraction 3.1
SPP 3.1
SBT 3.0
Dextrose 3.0
Cilostazol 3.0
Botox 3.0
CoCl2 3.0
more...
Enzyme
hydrogenase maturation endopeptidase 11.7
CD10 11.7
neprilysin-2 11.1
aminopeptidase W 11.0
EC 3.4.17.16 10.7
Scytalidium lignicolum acid proteinase 10.7
endopeptidase I 10.7
clostridial aminopeptidase 10.7
GluSGP 10.7
cathepsin-L1 10.1
physarolisin 10.1
peptide hormone inactivating endopeptidase 10.1
oligoendopeptidase F 10.1
thimet oligopeptidase 10.0
neurolysin 10.0
proteinase yscD 9.9
endothelin-converting enzyme 9.7
carboxypeptidase Taq 9.7
dipeptidyl-dipeptidase 9.7
EC 2.3.1.110 9.7
asclepain 9.5
meprin B 9.3
beta-lytic protease 9.3
adenain 9.1
kumamolysin 9.1
insulin-degrading enzyme 9.0
aminopeptidase P 8.8
cucumisin 8.7
lysostaphin 8.6
CD13 8.6
DD-carboxypeptidase 8.4
prolyl endopeptidase 8.4
CPN 8.4
alpha-methylacyl-CoA racemase 8.3
oligopeptidase A 8.2
aminopeptidase A 8.1
TdT 8.1
DD-carboxypeptidase 8.0
duodenase 8.0
nardilysin 8.0
meprin 8.0
nepenthesin 8.0
legumain 7.9
aminopeptidase B 7.8
astacin 7.8
adamalysin 7.7
DAP II 7.7
tripeptidase 7.6
D-aminopeptidase 7.6
serralysin 7.5
enkephalinase B 7.5
alanine carboxypeptidase 7.5
thermolysin 7.5
stratum corneum chymotryptic enzyme 7.4
matrilysin-2 7.3
tripeptidyl peptidase 7.3
PepX 7.3
glycoprotease 7.3
pancreatic elastase 2 7.3
murein hydrolase 7.2
carboxypeptidase E 7.2
proteinase A 7.2
deuterolysin 7.1
proteinase yscB 7.1
dipeptidyl peptidase IV 7.1
streptopain 7.1
cathepsin H 7.1
cathepsin X 7.0
tetanus neurotoxin 7.0
botulinum neurotoxin 7.0
oligopeptidase B 7.0
chymotrypsin C 7.0
proline iminopeptidase 7.0
bothropasin 6.9
bleomycin hydrolase 6.9
pyroglutamate aminopeptidase 6.9
CPM 6.8
proteinase A 6.8
carboxypeptidase D 6.7
clostripain 6.7
more...
Compound
Candoxatrilat 11.6
Thiorphan 10.9
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
C19H20N2O3 10.7
Phosphoramidon 10.5
Malvin 10.1
C19H20N2O3 10.1
7-(phenyl(8-quinolinylamino)methyl)-8-quinolinol 10.1
C19H20N2O3 10.1
C19H20N2O3 10.1
C11H13NO2 10.1
Z-Gly-Pro-Leu-Gly-Pro 9.9
Ebelactone B 9.8
Carfecillin 9.7
C19H18N2O3 9.3
Pratensein 9.3
DADT 9.1
Amastatin 8.8
Actinonin 8.4
C17H17NO4 8.3
C16H12N2O 8.2
2-Naphthylamine 8.1
Teprotide 8.0
Z-Gly-Pro 8.0
Z-Arg-Arg-NHMec 7.8
2-methylpentanoic acid 7.8
4-hydrazinobenzoic acid 7.7
Kallidin 7.6
Azocoll 7.6
Bestatin 7.5
Vancomycin hydrochloride 7.5
BMN 7.5
7-methoxy-2H-chromen-2-one 7.5
4-hydrazinobenzoic acid 7.5
C6H12O5 7.4
Enalaprilat 7.4
Azocasein 7.3
APN 7.3
Nitroxoline 7.2
Globomycin 7.2
Bromelia 7.2
diphenyl phosphonate 7.1
Diisopropyl fluorophosphate 7.1
Angiotensin I 7.1
Z-Gly 7.0
Leupeptin 7.0
CD 3 6.9
4-phenyl-2-butanone 6.9
His-Leu 6.8
Glycylglycine 6.8
1H-benzo[de]isoquinoline-1,3(2H)-dione 6.8
meso-diaminopimelate 6.7
THP-ADM 6.7
4-phenyl-2-butanone 6.7
MME 6.7
Hoe 6.7
Leupeptin 6.7
4-oxobutanoic acid 6.6
Arg-vasopressin 6.6
Fast Red TR 6.5
E-64 6.5
NMHE 6.5
Dansyl 6.4
Dolasetron 6.4
LDS-751 6.4
dihydrosphingosine-1-phosphate 6.4
Bradykinin 6.4
Pepstatin 6.3
PMSF 6.3
Oxaprozin 6.3
BNP 6.3
C14H19N3O4 6.2
4-methylpentanoic acid 6.2
more...