Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.5 (cathepsin D)
 4,130 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
TBC1 domain family member 14 12.9
ADAM 32 12.9
peroxisomal biogenesis factor 3 12.9
cathepsin D 12.8
isochorismatase domain containing 1 11.9
Rab40A 11.9
cadherin EGF LAG seven-pass G-type receptor 1 11.9
C14orf133 11.9
ubiquitin specific peptidase 10 11.9
GNPTAG 11.6
lysosome-associated protein transmembrane 4 beta 11.3
PTAR1 11.3
RAB2A, member RAS oncogene family 11.3
SNC73 11.3
ATP6V0A1 11.3
PDA2 11.3
cathepsin E 11.1
RAB9B 10.9
CARP-2 10.9
RABGGTB 10.9
CD84-H1 10.9
PL48 10.9
cathepsin B1 10.8
DAP-1 10.7
gastricsin 10.6
ADAM30 10.6
gamma-synergin 10.6
engrailed homeobox 1 10.6
NESG1 10.6
CVAK104 10.6
KIF5A protein 10.6
transcription factor binding to IGHM enhancer 3 10.6
tryptophan-tRNA ligase 10.6
ubiquinol-cytochrome c reductase binding protein 10.6
MP78 10.6
Syt V 10.6
TGOLN2 10.6
CLN6 protein 10.3
RBQ3 10.3
TBC1D14 10.3
ubiquitin carrier protein E2 10.3
mutant CLN3 10.1
ATP13A2 protein 10.1
SEZ6L2 10.1
gamma2-adaptin 10.1
TUBA1 10.1
IGL@ 10.1
FBXO27 10.1
ZnT-6 10.1
actin related protein 2/3 complex 10.1
CT120 10.1
mucolipin 3 10.1
Cathepsin H 10.0
BAG-2 9.9
TMEM55B 9.9
TEF-5 9.9
Aftiphilin 9.9
ATP6V0D1 9.9
DAP-3 9.9
MOX2 9.9
NDUFB5 9.9
APR-1 9.8
EBAG9 9.8
APBB1 9.8
CTSB 9.8
aspartyl protease 9.8
ZnT-7 9.7
ALCAT1 9.7
NCL protein 9.7
TP53RK 9.7
RAB26 9.7
SNAPIN 9.7
lipophilin B 9.7
M6PR 9.6
DAP-5 9.6
HIP2 9.6
plasma glutamate carboxypeptidase 9.6
MCOLN3 9.6
nclf 9.6
Transmembrane protein 192 9.6
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Disease
placental cancer 10.9
WBC diseases 10.9
CLN10 10.9
Postpartum cardiomyopathy 10.6
CLN7 9.8
CLN9 9.7
SAPD 9.7
Morgagnian cataract 9.6
stage IIB cervical cancer 9.5
ML III 9.2
EBSS 8.9
CLN8 8.8
Granular corneal dystrophy 8.7
CLN5 8.6
Macular corneal dystrophy 8.5
CLN6 8.4
Bayle 8.2
neuronal ceroid lipofuscinosis 8.1
Mucolipidosis 8.1
SCCD 8.0
stage IB cervical cancer 8.0
benign proliferative breast disease 7.9
familial hyperlipoproteinemia 7.8
DIOS 7.8
Tubular carcinoma 7.8
KRS 7.7
EPPS 7.7
grade I meningioma 7.4
Recurrent seizures 7.3
CLN1 7.2
Kufs' disease 7.2
Unicameral bone cyst 6.9
CLN3 6.7
CLN2 6.7
IRMA 6.7
HCHWA 6.6
GFD 6.5
Intestinal infection 6.5
iris melanoma 6.4
Peripartum cardiomyopathy 6.4
hypertensive cardiomyopathy 6.3
fibrocystic breast disease 6.2
HOPS 6.2
SPG11 6.2
Salivary duct carcinoma 6.0
Danon disease 6.0
mixed gliomas 5.9
Pemphigus foliaceus 5.9
Medullary carcinoma 5.9
generalized tuberculosis 5.8
mouse leukemia L1210 5.7
infiltrating ductal carcinoma 5.6
stage II breast cancer 5.6
erythroplakia 5.6
malignant state 5.5
Hurler 5.5
fibrocystic disease 5.5
HS3 5.5
apocrine metaplasia 5.5
multicentric Castleman's disease 5.5
Alpers 5.4
Lowe syndrome 5.4
Schistosoma japonicum 5.4
lysosomal storage disease 5.4
DMC 5.3
Malassez 5.3
TRPS1 5.3
myoblastoma 5.3
FTLD 5.3
Goldblatt hypertension 5.3
Arthus reaction 5.2
terminal disease 5.2
Goldblatt 5.1
Desmoplastic 5.1
Niemann-Pick 5.1
MSF 5.1
supraglottis 5.0
Retinal degeneration 5.0
Netherton syndrome 5.0
Enzyme inhibition 4.9
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Symptom
Spots 5.1
disturbed balance 5.1
Decreased activity 4.9
autodigestion 4.6
joint stiffness 4.5
Anoxia 3.8
hypoproteinemia 3.8
starvation 3.5
HSA 3.4
dry skin 2.9
microbial colonization 2.9
abnormal gait 2.8
cachexia 2.8
hypertonia 2.6
acidity 2.6
chronic constipation 2.6
hyperoxia 2.6
skin damage 2.3
despair 2.3
spasticity 1.8
acute stress 1.7
collapse 1.1
functional recovery 0.8
anorexia 0.7
exhaustion 0.2
arthralgia 0.1
seizures 0.1
spasm 0.1
regurgitation -0.1
syncope -0.3
splenomegaly -0.4
low back pain -0.4
constipation -0.4
thinning -0.5
nausea -0.6
erythema -0.8
hypothermia -1.2
tremor -1.3
weakness -1.3
angina -1.5
fatigue -1.7
overweight -1.8
dyspnea -1.9
analgesia -1.9
vomiting -2.0
anesthesia -2.8
diarrhea -2.9
pain -3.5
Drug
Isorenin 11.6
Pepstatin 10.8
Methylprednisolone succinate 10.3
Pro-Banthine 9.5
Bv2 9.5
CA-074 9.3
Cimaterol 7.5
Ammonium chloride 7.0
Cortrosyn 7.0
Brij 96 6.9
Cortrosyn 6.7
Ceredase 6.7
Cerezyme 6.2
Gemifloxacin 6.1
Fulvestrant 6.0
RFP 6.0
Pertuzumab 5.9
uPA 5.6
PFT 5.6
3-Methyladenine 5.5
Casodex 5.3
ICI 5.3
Ranibizumab 5.2
Talc 5.2
Monensin 5.0
Thyroglobulin 5.0
CER 4.8
Papain 4.8
Bestatin 4.7
Senna 4.6
Urokinase 4.6
Senna 4.6
Meconium 4.6
Tao 4.3
SMP 4.3
balanced salt solution 4.3
Cilostazol 4.2
Hyaluronidase 4.1
Moxifloxacin 4.1
ISP 4.0
Asn 4.0
Hyaluronidase 4.0
PFA 3.9
Fraction 3.9
Iloprost 3.9
NAG 3.8
Estrogens 3.8
BCG vaccine 3.8
Metrizamide 3.7
ZnCl2 3.6
ZnCl2 3.6
Phosphatidylserine 3.5
Tocopherol 3.5
Gel 3.4
Camp 3.4
Prednisolone 3.4
Bupivacaine 3.3
Silica 3.3
Albumin 3.3
Norplant 3.2
Angiotensin II 3.2
Gelatin 3.2
Aprotinin 3.1
Photofrin 3.1
DFP 3.1
Parkin 3.0
TTC 3.0
Parkin 3.0
DDAVP 3.0
DDAVP 3.0
Growth hormone 3.0
Growth hormone 2.9
Propofol 2.9
Retinoic acid 2.8
Herceptin 2.8
AMC 2.7
L-tyrosine 2.7
Vitamin B 2.6
Methylene blue 2.6
CTC 2.6
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Enzyme
cathepsin D 12.9
plasmepsin I 11.0
plasmepsin II 10.9
gastricsin 10.8
nepenthesin 10.7
phosphoglucokinase 10.6
cathepsin T 10.6
Candida albicans aspartic proteinase 10.6
N-acetylglucosaminylphosphotransferase 10.5
alpha-N-acetylglucosaminyl phosphodiesterase 10.4
SMP 9.9
carboxyl proteinase 9.9
cathepsin F 9.7
cathepsin B 9.4
cathepsin H 9.4
cathepsin C 9.4
phytepsin 9.3
cathepsin O 9.3
stratum corneum chymotryptic enzyme 9.2
beta-glycerophosphatase 9.2
rhizopuspepsin 9.0
yapsin 1 9.0
NS protease 8.9
proteinase A 8.9
cathepsin L 8.8
DAP II 8.7
cathepsin V 8.5
aminopeptidase Y 8.5
endothiapepsin 8.4
deuterolysin 8.4
DNase II 8.3
proteinase A 8.3
cathepsin X 8.3
chymosin 8.1
tripeptidyl peptidase 8.1
EC 2.4.99.1 8.1
methylmalonate-semialdehyde dehydrogenase 8.0
ficin 7.8
glutathione-insulin transhydrogenase 7.8
KLK7 7.7
carboxypeptidase S 7.7
MT 1 7.7
cathepsin G 7.7
aspartyl aminopeptidase 7.6
alpha-N-acetylglucosaminidase 7.6
penicillopepsin 7.6
galactosylhydroxylysyl glucosyltransferase 7.5
beta-secretase 7.5
memapsin 2 7.5
legumain 7.5
Rab geranylgeranyltransferase 7.5
hexosaminidase 7.4
m-AAA protease 7.4
arylsulfatase A 7.3
cathepsin S 7.3
thimet oligopeptidase 7.2
pepsin 7.2
acid phosphatase 7.2
beta-glucuronidase 7.2
aminopeptidase B 7.2
pyroglutamate aminopeptidase 7.1
alpha-L-fucosidase 7.1
UDP-N-acetylglucosamine pyrophosphorylase 7.1
CPA2 7.1
aminopeptidase I 7.0
carboxypeptidase Y 7.0
alpha-mannosidase 6.9
stromelysin-3 6.9
palmitoyl-protein thioesterase 6.9
arylsulfatase 6.8
m-calpain 6.8
glucosamine-6-phosphate deaminase 6.8
sulfatase 6.7
glucocerebrosidase 6.6
choline dehydrogenase 6.6
bleomycin hydrolase 6.6
endoglycosidase H 6.5
alpha-L-fucosidase 6.5
alpha-L-fucosidase 6.5
matrix metalloproteinase 14 6.5
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Compound
6-cyclohexylhexanoic acid 11.9
6-cyclohexylhexanoic acid 11.9
C18H16O8 11.3
Gardenin B 10.9
Pepstatin 10.9
Gardenin 10.1
Pinane 10.0
Methyl caffeate 9.7
A 435 9.7
Cyprodinil 9.3
5-phenylpentanoic acid 9.2
Hydroxytamoxifen 9.1
CMP-N-acetylneuraminate 9.0
CMP-N-acetylneuraminate 9.0
Xanthomicrol 9.0
3-methylbenzaldehyde 8.9
Benzophenone-1 8.7
1H-indole-3-carbaldehyde 8.6
Fast Garnet GBC 8.6
1H-indole-3-carbaldehyde 8.6
1H-indole-3-carbaldehyde 8.6
Trimethyltin chloride 8.6
1H-indole-3-carbaldehyde 8.6
1H-indole-3-carbaldehyde 8.6
Leupeptin 8.6
1H-indole-3-carbaldehyde 8.4
1H-indole-3-carbaldehyde 8.3
Leupeptin 8.3
Citreoviridin 8.2
EPNP 8.2
Ginkgetin 8.2
Aziridine 8.1
1H-indole-3-carbaldehyde 8.1
2-ethoxy-2-oxoethyl 8.1
Streptolydigin 8.0
1H-indole-3-carbaldehyde 7.9
Anisodamine 7.9
1H-indole-3-carbaldehyde 7.8
Bisphenol AF 7.7
hydroxyethylamine 7.7
PAMBA 7.6
Statin 7.4
Tiapamil 7.4
E-64 7.4
Brucine 7.3
N-Hydroxysuccinimide 7.3
KNI-272 7.3
Mr 30 7.2
DPBS 7.2
Anacardic acid 7.1
Lynestrenol 7.1
N-acetyltryptophan 7.0
N-acetyltryptophan 7.0
Procion Yellow 7.0
His-Leu 6.9
Zinc pyrithione 6.8
CLTC 6.8
Zinc pyrithione 6.8
Zinc pyrithione 6.8
Angiotensin I 6.8
Pentobarbital 6.7
Medroxyprogesterone 6.6
Acridine Orange 6.5
Acridine Orange 6.5
Acridine Orange 6.5
UDP-GlcNAc 6.5
beta-tocopherol 6.5
Fast Blue B 6.4
TPCK 6.4
Pipecolic acid 6.3
glucose-6-phosphate 6.3
PMSF 6.2
Tanakan 6.2
TCTP 6.2
4-chlorobenzoic acid 6.2
2-OHE1 6.2
norleucine 6.2
NIX 6.1
DFD 6.1
methyl butyrate 6.1
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