Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.5 (cathepsin D)
4,130 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
peroxisomal biogenesis factor 3 12.9
TBC1 domain family member 14 12.9
ADAM 32 12.9
cathepsin D 12.8
ubiquitin specific peptidase 10 11.9
isochorismatase domain containing 1 11.9
C14orf133 11.9
cadherin EGF LAG seven-pass G-type receptor 1 11.9
Rab40A 11.9
GNPTAG 11.6
PTAR1 11.3
SNC73 11.3
ATP6V0A1 11.3
PDA2 11.3
lysosome-associated protein transmembrane 4 beta 11.3
RAB2A, member RAS oncogene family 11.3
cathepsin E 11.1
RAB9B 10.9
CARP-2 10.9
CD84-H1 10.9
RABGGTB 10.9
PL48 10.9
cathepsin B1 10.8
DAP-1 10.7
gastricsin 10.6
tryptophan-tRNA ligase 10.6
engrailed homeobox 1 10.6
ADAM30 10.6
Syt V 10.6
gamma-synergin 10.6
MP78 10.6
KIF5A protein 10.6
NESG1 10.6
CVAK104 10.6
transcription factor binding to IGHM enhancer 3 10.6
ubiquinol-cytochrome c reductase binding protein 10.6
TGOLN2 10.6
ubiquitin carrier protein E2 10.3
CLN6 protein 10.3
TBC1D14 10.3
more...
Disease
placental cancer 10.9
WBC diseases 10.9
CLN10 10.9
Postpartum cardiomyopathy 10.6
CLN7 9.8
SAPD 9.7
CLN9 9.7
Morgagnian cataract 9.6
stage IIB cervical cancer 9.5
ML III 9.2
EBSS 8.9
CLN8 8.8
Granular corneal dystrophy 8.7
CLN5 8.6
Macular corneal dystrophy 8.5
CLN6 8.4
Bayle 8.2
neuronal ceroid lipofuscinosis 8.1
Mucolipidosis 8.1
SCCD 8.0
stage IB cervical cancer 8.0
benign proliferative breast disease 7.9
familial hyperlipoproteinemia 7.8
DIOS 7.8
Tubular carcinoma 7.8
KRS 7.7
EPPS 7.7
grade I meningioma 7.4
Recurrent seizures 7.3
CLN1 7.2
Kufs' disease 7.2
Unicameral bone cyst 6.9
CLN3 6.7
CLN2 6.7
IRMA 6.7
HCHWA 6.6
GFD 6.5
Intestinal infection 6.5
iris melanoma 6.4
Peripartum cardiomyopathy 6.4
more...
Symptom
Spots 5.1
disturbed balance 5.1
Decreased activity 4.9
autodigestion 4.6
joint stiffness 4.5
Anoxia 3.8
hypoproteinemia 3.8
starvation 3.5
HSA 3.4
dry skin 2.9
microbial colonization 2.9
cachexia 2.8
abnormal gait 2.8
hypertonia 2.6
acidity 2.6
chronic constipation 2.6
hyperoxia 2.6
skin damage 2.3
despair 2.3
spasticity 1.8
acute stress 1.7
collapse 1.1
functional recovery 0.8
anorexia 0.7
exhaustion 0.2
arthralgia 0.1
seizures 0.1
spasm 0.1
regurgitation -0.1
syncope -0.3
splenomegaly -0.4
low back pain -0.4
constipation -0.4
thinning -0.5
nausea -0.6
erythema -0.8
hypothermia -1.2
tremor -1.3
weakness -1.3
angina -1.5
more...
Drug
Isorenin 11.6
Pepstatin 10.8
Methylprednisolone succinate 10.3
Bv2 9.5
Pro-Banthine 9.5
CA-074 9.3
Cimaterol 7.5
Ammonium chloride 7.0
Cortrosyn 7.0
Brij 96 6.9
Ceredase 6.7
Cortrosyn 6.7
Cerezyme 6.2
Gemifloxacin 6.1
Fulvestrant 6.0
RFP 6.0
Pertuzumab 5.9
uPA 5.6
PFT 5.6
3-Methyladenine 5.5
Casodex 5.3
ICI 5.3
Ranibizumab 5.2
Talc 5.2
Monensin 5.0
Thyroglobulin 5.0
CER 4.8
Papain 4.8
Bestatin 4.7
Senna 4.6
Urokinase 4.6
Senna 4.6
Meconium 4.6
Tao 4.3
SMP 4.3
balanced salt solution 4.3
Cilostazol 4.2
Hyaluronidase 4.1
Moxifloxacin 4.1
ISP 4.0
more...
Enzyme
cathepsin D 12.9
plasmepsin I 11.0
plasmepsin II 10.9
gastricsin 10.8
nepenthesin 10.7
phosphoglucokinase 10.6
Candida albicans aspartic proteinase 10.6
cathepsin T 10.6
N-acetylglucosaminylphosphotransferase 10.5
alpha-N-acetylglucosaminyl phosphodiesterase 10.4
SMP 9.9
carboxyl proteinase 9.9
cathepsin F 9.7
cathepsin B 9.4
cathepsin H 9.4
cathepsin C 9.4
phytepsin 9.3
cathepsin O 9.3
stratum corneum chymotryptic enzyme 9.2
beta-glycerophosphatase 9.2
rhizopuspepsin 9.0
yapsin 1 9.0
NS protease 8.9
proteinase A 8.9
cathepsin L 8.8
DAP II 8.7
cathepsin V 8.5
aminopeptidase Y 8.5
endothiapepsin 8.4
deuterolysin 8.4
DNase II 8.3
proteinase A 8.3
cathepsin X 8.3
chymosin 8.1
tripeptidyl peptidase 8.1
EC 2.4.99.1 8.1
methylmalonate-semialdehyde dehydrogenase 8.0
ficin 7.8
glutathione-insulin transhydrogenase 7.8
KLK7 7.7
more...
Compound
6-cyclohexylhexanoic acid 11.9
6-cyclohexylhexanoic acid 11.9
C18H16O8 11.3
Gardenin B 10.9
Pepstatin 10.9
Gardenin 10.1
Pinane 10.0
Methyl caffeate 9.7
A 435 9.7
Cyprodinil 9.3
5-phenylpentanoic acid 9.2
Hydroxytamoxifen 9.1
Xanthomicrol 9.0
CMP-N-acetylneuraminate 9.0
CMP-N-acetylneuraminate 9.0
3-methylbenzaldehyde 8.9
Benzophenone-1 8.7
1H-indole-3-carbaldehyde 8.6
Fast Garnet GBC 8.6
1H-indole-3-carbaldehyde 8.6
1H-indole-3-carbaldehyde 8.6
1H-indole-3-carbaldehyde 8.6
Trimethyltin chloride 8.6
1H-indole-3-carbaldehyde 8.6
Leupeptin 8.6
1H-indole-3-carbaldehyde 8.4
1H-indole-3-carbaldehyde 8.3
Leupeptin 8.3
Citreoviridin 8.2
EPNP 8.2
Ginkgetin 8.2
Aziridine 8.1
1H-indole-3-carbaldehyde 8.1
2-ethoxy-2-oxoethyl 8.1
Streptolydigin 8.0
Anisodamine 7.9
1H-indole-3-carbaldehyde 7.9
1H-indole-3-carbaldehyde 7.8
Bisphenol AF 7.7
hydroxyethylamine 7.7
more...