Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.5 (cathepsin D)
4,130 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
cathepsin D 4126
cathepsin B 377
Mol 292
Sep 275
acid phosphatase 236
cathepsin 172
renin 169
beta-glucuronidase 149
hemoglobin 145
estrogen receptor 116
cathepsin L 113
endoplasmic reticulum 107
p53 105
caspase-3 102
LC3 101
SDS 95
pS2 93
aspartyl protease 92
collagen 90
amyloid precursor protein 85
insulin 82
cathepsin E 81
p62 81
glycoprotein 78
mannose 6-phosphate receptor 76
progesterone receptor 76
LAMP-1 74
membrane protein 73
ubiquitin 64
fibronectin 63
polypeptide 61
erbB-2 58
serum albumin 56
chymotrypsin 55
ATP 54
Ang II 53
ATPase 53
peptidase 50
proteasome 49
Rab7 48
more...
Disease
cancer 432
breast cancer 385
tumor 364
Alzheimer's disease 176
carcinoma 110
MCF 104
SDS 95
metastases 77
ischemia 52
hepatocellular carcinoma 51
tumor progression 44
Parkinson's disease 41
neuronal ceroid lipofuscinosis 39
tumor growth 37
diabetes 32
carcinogenesis 31
colorectal cancer 30
hypertension 29
HIV 27
adenocarcinoma 26
dementia 26
prostate cancer 25
ovarian cancer 24
uterus 23
malaria 23
neuroblastoma 22
arthritis 21
melanoma 21
tuberculosis 20
atherosclerosis 20
Mycobacterium 20
plaque 19
aggressiveness 18
osteoarthritis 18
tumorigenesis 17
rheumatoid arthritis 17
leukemia 17
ICD 16
myocardial ischemia 16
celiac disease 16
more...
Symptom
starvation 37
acidity 12
seizures 11
collapse 8
cachexia 5
hyperoxia 4
HSA 4
spasticity 3
anorexia 3
joint stiffness 3
pain 3
functional recovery 3
Decreased activity 2
acute stress 2
fatigue 2
weakness 2
exhaustion 2
hypoproteinemia 2
nausea 2
Spots 2
anesthesia 2
tremor 1
autodigestion 1
erythema 1
disturbed balance 1
low back pain 1
skin damage 1
dyspnea 1
abnormal gait 1
spasm 1
splenomegaly 1
syncope 1
dry skin 1
diarrhea 1
Anoxia 1
vomiting 1
arthralgia 1
analgesia 1
hypertonia 1
hypothermia 1
more...
Drug
Dermatol 34
lysine 30
Pepstatin 28
ICI 28
Asn 24
Gel 21
Cardiovasc 15
ROS 14
uPA 13
NADH 12
CSF 11
RFP 10
vitamin E 9
CA-074 9
IFN-gamma 7
Angiotensin II 6
Albumin 6
Fraction 5
MAP 5
Leaf 5
Ammonium chloride 4
Estrogens 4
CaCl2 4
ascorbate 4
CaCl2 4
CaCl2 4
Monensin 4
NAG 4
balanced salt solution 4
EE2 4
IL-2 4
Retinoic acid 3
caffeine 3
PTH 3
Growth hormone 3
Growth hormone 3
Fulvestrant 3
PFT 3
Adriamycin 3
Silica 3
more...
Enzyme
cathepsin D 4130
cathepsin B 377
acid phosphatase 241
pepsin 170
renin 169
beta-glucuronidase 143
trypsin 136
cathepsin L 113
SMP 86
hexosaminidase 78
caspase-3 75
CD10 61
peroxidase 60
chymotrypsin 59
proteasome 58
urokinase-type plasminogen activator 57
ATPase 55
beta-galactosidase 53
plasmin 52
cathepsin G 47
collagenase 45
elastase 44
catalase 43
ERK 42
superoxide dismutase 42
sulfatase 42
papain 41
lysozyme 39
mitogen-activated protein kinase 39
alkaline phosphatase 38
lactate dehydrogenase 35
cathepsin C 34
cathepsin H 33
ACE 30
protein kinase 26
RNase 26
kallikrein 24
alpha-mannosidase 23
thrombin 23
endoglycosidase H 22
more...
Compound
Dec 264
DNA 209
cysteine 182
phosphate 147
galactose 128
Clin 128
Phe 125
sodium 121
leucine 117
oxygen 101
serine 99
SDS 98
alanine 97
arginine 86
sulfate 83
calcium 79
lysine 79
Asp 75
methionine 65
water 64
Pepstatin 60
nitrogen 57
tyrosine 56
glucose 55
ATP 54
Gly 51
ammonium 48
MDA 47
NH2 46
Ile 45
His 43
urea 40
GlcNAc 37
glucose-6-phosphate 36
hydrogen 34
acetate 32
DEAE 32
Triton X-100 32
EDTA 32
EDTA 32
more...