Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.23.5 (
cathepsin D
)
4,130
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cathepsin D
4126
cathepsin B
377
Mol
292
Sep
275
acid phosphatase
236
cathepsin
172
renin
169
beta-glucuronidase
149
hemoglobin
145
estrogen receptor
116
cathepsin L
113
endoplasmic reticulum
107
p53
105
caspase-3
102
LC3
101
SDS
95
pS2
93
aspartyl protease
92
collagen
90
amyloid precursor protein
85
insulin
82
cathepsin E
81
p62
81
glycoprotein
78
mannose 6-phosphate receptor
76
progesterone receptor
76
LAMP-1
74
membrane protein
73
ubiquitin
64
fibronectin
63
polypeptide
61
erbB-2
58
serum albumin
56
chymotrypsin
55
ATP
54
Ang II
53
ATPase
53
peptidase
50
proteasome
49
Rab7
48
more...
Disease
cancer
432
breast cancer
385
tumor
364
Alzheimer's disease
176
carcinoma
110
MCF
104
SDS
95
metastases
77
ischemia
52
hepatocellular carcinoma
51
tumor progression
44
Parkinson's disease
41
neuronal ceroid lipofuscinosis
39
tumor growth
37
diabetes
32
carcinogenesis
31
colorectal cancer
30
hypertension
29
HIV
27
adenocarcinoma
26
dementia
26
prostate cancer
25
ovarian cancer
24
uterus
23
malaria
23
neuroblastoma
22
arthritis
21
melanoma
21
tuberculosis
20
atherosclerosis
20
Mycobacterium
20
plaque
19
aggressiveness
18
osteoarthritis
18
tumorigenesis
17
rheumatoid arthritis
17
leukemia
17
ICD
16
myocardial ischemia
16
celiac disease
16
more...
Symptom
starvation
37
acidity
12
seizures
11
collapse
8
cachexia
5
hyperoxia
4
HSA
4
spasticity
3
anorexia
3
joint stiffness
3
pain
3
functional recovery
3
Decreased activity
2
acute stress
2
fatigue
2
weakness
2
exhaustion
2
hypoproteinemia
2
nausea
2
Spots
2
anesthesia
2
tremor
1
autodigestion
1
erythema
1
disturbed balance
1
low back pain
1
skin damage
1
dyspnea
1
abnormal gait
1
spasm
1
splenomegaly
1
syncope
1
dry skin
1
diarrhea
1
Anoxia
1
vomiting
1
arthralgia
1
analgesia
1
hypertonia
1
hypothermia
1
more...
Drug
Dermatol
34
lysine
30
Pepstatin
28
ICI
28
Asn
24
Gel
21
Cardiovasc
15
ROS
14
uPA
13
NADH
12
CSF
11
RFP
10
vitamin E
9
CA-074
9
IFN-gamma
7
Angiotensin II
6
Albumin
6
Fraction
5
MAP
5
Leaf
5
Ammonium chloride
4
Estrogens
4
CaCl2
4
ascorbate
4
CaCl2
4
CaCl2
4
Monensin
4
NAG
4
balanced salt solution
4
EE2
4
IL-2
4
Retinoic acid
3
caffeine
3
PTH
3
Growth hormone
3
Growth hormone
3
Fulvestrant
3
PFT
3
Adriamycin
3
Silica
3
more...
Enzyme
cathepsin D
4130
cathepsin B
377
acid phosphatase
241
pepsin
170
renin
169
beta-glucuronidase
143
trypsin
136
cathepsin L
113
SMP
86
hexosaminidase
78
caspase-3
75
CD10
61
peroxidase
60
chymotrypsin
59
proteasome
58
urokinase-type plasminogen activator
57
ATPase
55
beta-galactosidase
53
plasmin
52
cathepsin G
47
collagenase
45
elastase
44
catalase
43
ERK
42
superoxide dismutase
42
sulfatase
42
papain
41
lysozyme
39
mitogen-activated protein kinase
39
alkaline phosphatase
38
lactate dehydrogenase
35
cathepsin C
34
cathepsin H
33
ACE
30
protein kinase
26
RNase
26
kallikrein
24
alpha-mannosidase
23
thrombin
23
endoglycosidase H
22
more...
Compound
Dec
264
DNA
209
cysteine
182
phosphate
147
galactose
128
Clin
128
Phe
125
sodium
121
leucine
117
oxygen
101
serine
99
SDS
98
alanine
97
arginine
86
sulfate
83
calcium
79
lysine
79
Asp
75
methionine
65
water
64
Pepstatin
60
nitrogen
57
tyrosine
56
glucose
55
ATP
54
Gly
51
ammonium
48
MDA
47
NH2
46
Ile
45
His
43
urea
40
GlcNAc
37
glucose-6-phosphate
36
hydrogen
34
acetate
32
DEAE
32
Triton X-100
32
EDTA
32
EDTA
32
more...