Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.23.5 (
cathepsin D
)
4,130
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Cathepsin D activity and the content of proteins and acid-soluble tyrosine in the walls of
varicose veins
, thrombophlebitic
varicose veins
and normal saphenous veins were determined. It was found that the
cathepsin D
activity in the wall of
varicose veins
is almost 1.5 times as high as that activity in a thrombophlebitic
varicose vein
wall and more than 3 times higher than in the wall of a normal vein. The acid-soluble tyrosine content of the
varicose vein
was slightly higher than that of the normal vein, whereas the content of the thrombophlebitic
varicose vein
was more than 1.5 times as high as that of the normal vein. Cathepsin D has a destructive effect on the
varicose vein
wall and accelerates the removal of thrombi in varicophlebitis.
...
PMID:Cathepsin D activity and protein degradation products content in the walls of varicose veins of the lower limbs. 726 38
