Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.17 (PCE)
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Human Gene/Protein
AD14 13.0
PN-II 11.8
DAMS 10.9
TLN 10.1
PCA1 9.6
HAB1 9.5
BB1 9.1
MAI 9.0
Trf 8.8
SULF1 8.8
pancreatic cholesterol esterase 8.5
BTF 8.5
TUTase 8.4
OSC 8.3
BPR 8.3
GREB1 8.0
4F) 7.9
MNF 7.8
SGT 7.6
FEL 7.5
CHN2 7.5
retina-specific 7.5
TIE 7.5
anchor protein 7.4
CPN 7.4
FMT 7.3
NEU 7.3
FTO 7.2
OSX 7.1
BTP 7.1
galectin-8 7.1
aminopeptidase B 7.0
prohormone convertase 7.0
PEN 7.0
PSS 6.9
TSG 6.9
PMD 6.9
UPS 6.9
OGF 6.8
ASS 6.8
IscU 6.8
PE2 6.8
OV-1 6.6
FCE 6.6
DNT 6.6
heparin-binding EGF-like growth factor 6.5
AML3 6.5
FRS2 6.5
trypsin-like serine protease 6.4
TCB 6.4
CYC 6.4
AE2 6.4
LPH 6.3
CPZ 6.3
PCP 6.3
ECI 6.3
RECQL4 6.3
SPP 6.2
ACF 6.1
cholesterol esterase 6.1
PGR 6.1
TCA 6.1
HTL 6.0
CGT 5.9
PC1/3 5.9
hole 5.9
Aspartate aminotransferase 5.9
CFC 5.9
endoprotease 5.8
CBD 5.8
MSU 5.8
CREST 5.8
DCP 5.8
CHL 5.8
PC2 5.7
SHE 5.7
FPP 5.7
PIM 5.6
CD138 5.6
CAV 5.6
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Disease
Peritoneal metastases 10.0
public drinking 9.3
TD2 8.6
TD1 8.3
Echinococcus granulosus infection 8.2
TCO 8.0
non-gonococcal urethritis (NGU) 7.8
alcohol effect 7.8
BGS 7.5
DMM 7.5
FAB M4 7.3
leukorrhea 7.2
DBA2 7.0
PSS 6.9
PSS 6.9
PMD 6.9
delirium tremens 6.7
SM1 6.6
Mixed infection 6.5
sick building syndrome 6.5
acute pharyngitis 6.4
DNT 6.4
HTL 6.1
OSX 6.1
Sezary syndrome 5.9
non-gonococcal urethritis 5.9
Marion 5.9
Bezold 5.9
CSE 5.7
FPP 5.7
psittacosis 5.7
EMD 5.7
PBT 5.6
IRMA 5.5
PCP 5.4
Pelizaeus-Merzbacher disease 5.4
Chlamydia trachomatis infection 5.3
NMS 5.3
GSD 5.3
familial hemophagocytic lymphohistiocytosis 5.3
trichomoniasis 5.2
postmenopausal bone loss 5.2
WSN 5.2
WSN 5.1
CREST 5.1
GSD 5.1
TCP 5.1
PSS 5.1
trypanosomiasis 4.9
ischemic optic neuropathy 4.9
NMS 4.8
trichotillomania 4.7
maple syrup urine disease 4.7
Testes 4.6
SSM 4.6
protein-losing enteropathy 4.6
Testis 4.6
Testis 4.6
cervicitis 4.5
overnutrition 4.5
ICT 4.5
Ovary 4.5
idiopathic dilated cardiomyopathy 4.3
schistosomiasis 4.2
PIN 4.2
drug usage 4.2
chemical carcinogenesis 4.1
Chlamydia 3.9
Wells 3.9
folate deficiency 3.9
hyperlipoproteinemia 3.9
PCL 3.8
refractive error 3.8
Schistosoma mansoni 3.8
alopecia areata 3.8
Ovary 3.7
AS1 3.7
urethritis 3.7
atherosclerotic cardiovascular disease 3.7
TAM 3.6
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Symptom
strangury 9.5
Hyperextension 8.2
labored breathing 6.9
body pain 6.5
flushing 6.2
clonus 5.1
microbial colonization 4.5
dry eye 3.2
exhaustion 2.4
vertigo 1.8
agitation 1.0
overweight 0.9
ataxia 0.6
hypothermia 0.5
respiratory distress 0.3
seizures 0.3
cough 0.0
starvation -0.0
diarrhea -0.2
weakness -0.6
pain -1.4
Drug
Pregnyl 8.6
Ethane 8.5
Teniposide 8.0
Dimethylformamide 7.6
APM 7.1
Tween 40 7.0
PE2 6.8
PCP 6.3
CPZ 6.3
Artesunate 6.2
Camp 6.1
Amifostine 6.1
SPP 6.0
Vitamin B12 5.9
Mutagen 5.7
Glutamic acid 5.6
Triad 5.3
TiO2 5.2
Triad 5.2
ZnO 5.2
PCB 4.5
AMC 4.4
Fraction 4.2
VCR 4.0
Triclosan 3.9
PTC 3.8
Norplant 3.8
Fructose 3.7
ACT 3.5
citric acid 3.3
THF 3.2
Vitamin A 3.0
CTX 2.8
HCH 2.8
NH3 2.8
Ethanol 2.3
Glutathione 2.2
ampicillin 2.1
SiO2 2.0
EPA 1.8
Gel 1.7
ENT 1.5
vitamin E 1.5
ascorbate 1.1
Monit 1.1
ROS 0.3
caffeine 0.2
Leaf 0.2
NADH 0.2
lysine -0.3
Cardiovasc -3.0
Enzyme
PCE 14.6
tetrachloroethene reductive dehalogenase 13.5
EaCoMT 11.4
TUT 8.9
arylsulfate sulfotransferase 8.2
superoxide reductase 7.7
aminopeptidase B 6.8
CO dehydrogenase 6.8
pyruvate:ferredoxin oxidoreductase 6.7
proteinase A 6.5
PCP 6.3
cholesterol esterase 6.3
CPN 5.8
CGT 5.8
formate dehydrogenase 5.6
formate dehydrogenase 5.6
furin 5.5
formate dehydrogenase 5.5
hydrogenase 5.4
hydrogenase 5.4
fumarate reductase 5.3
cytochrome c peroxidase 5.1
methane monooxygenase 4.9
PST 4.9
PTA 4.9
Pla 4.8
ACS 4.6
proprotein convertase 4.5
AST 4.0
succinic dehydrogenase 3.8
demethylase 3.7
thermolysin 3.7
phytase 3.6
phytase 3.6
histidine kinase 3.3
acetyl-CoA carboxylase 3.1
aspartate aminotransferase 3.0
caspase-1 3.0
CPT 2.9
CPT 2.8
ACE 2.7
proteinase K 2.6
subtilisin 2.5
CPT 2.4
transcriptase 2.4
cholinesterase 1.9
alanine aminotransferase 1.9
urease 1.8
glutathione peroxidase 1.7
urease 1.7
glutathione S-transferase 1.7
beta-glucuronidase 1.7
xanthine oxidase 1.5
complex I 1.5
gamma-glutamyl transpeptidase 1.4
glutathione reductase 1.4
superoxide dismutase 1.3
monoamine oxidase 1.2
chymotrypsin 1.2
focal adhesion kinase 1.2
catalase 1.1
RNA polymerase 1.1
ERK 1.0
AMP-activated protein kinase 0.9
lactate dehydrogenase 0.7
reverse transcriptase 0.6
RNase 0.6
RNase 0.4
MEK 0.4
creatine kinase 0.4
peroxidase 0.2
alkaline phosphatase 0.0
acetylcholinesterase -0.2
trypsin -0.8
ATPase -1.4
Compound
Tetrabutoxysilane 14.6
PCE 14.6
naphtho[2,3-c]thiophene-4,9-dione 14.6
PCE 14.4
trans-1,3-Dichloropropene 13.6
Michler's base 13.6
Truxene 13.6
2-chloroethyl acrylate 13.6
C10H10O2 13.0
2'-Hydroxychalcone 12.6
Ethyl methacrylate 12.6
Thiocyclam 12.3
2-Heptyl-4-hydroxyquinoline-N-oxide 12.0
2,4-dimethyl-3-pentanol 11.8
TCE 11.6
2-(3-methoxyphenyl)cyclohexanone 11.4
1,8-dibromooctane 11.4
2-TCA 11.3
Trichloroethylene 11.2
1,2-dichloroethylene 11.2
1,2-dichloroethylene 11.0
Cubebin 10.8
C10H8O4 10.7
Benzyl Viologen 10.3
Ronicol 10.0
Ethyl lactate 9.9
Isethionate 9.8
1-chloronaphthalene 9.7
1,1,2-trichloroethane 9.7
Caprolactam 9.5
Phenolphthalein 9.3
Phenolphthalein 9.3
1,2,3,4-tetrachlorobenzene 9.2
7-Ethoxycoumarin 9.2
2,3-dichlorophenol 9.1
cyanoacetic acid 9.1
Vinyl chloride 9.0
2-bromoethanesulfonic acid 8.9
Mescaline 8.9
1,2,3-trichlorobenzene 8.9
MnO4 8.8
1,3,5-trichlorobenzene 8.7
1,1,1-trichloroethane 8.7
2,2-dimethoxypropane 8.6
Cyanocobalamin 8.6
acryloyl chloride 8.6
1,2-dichloropropane 8.5
1,2,4,5-tetrachlorobenzene 8.4
DCA 8.3
ethynylbenzene 8.3
Nerolidol 8.3
DCA 8.3
Nerolidol 8.3
Zingerone 8.3
1,3-dichlorobenzene 8.2
N-ethylurea 8.2
MIBK 8.2
trichloroacetonitrile 8.0
SCMC 8.0
Propoxur 8.0
Natamycin 7.9
Potassium permanganate 7.9
1,2-ethanedithiol 7.8
1,2-ethanedithiol 7.8
o-xylene 7.6
TPB 7.6
TCNE 7.6
DCB 7.6
chlorobenzene 7.5
2,1,3-benzothiadiazole 7.5
Benzothiazole 7.4
cysteate 7.4
4-NQO 7.4
Esculetin 7.4
Surfactin 7.3
DCVC 7.3
NEU 7.3
thiophene 7.2
DCB 7.2
Nandrolone 7.2
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