Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.23.17 (
PCE
)
1,301
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
High doses of a test chemical sometimes affect the food consumption of the treated animals even to the point of
starvation
. The effect of such a non-specific toxicological stress on the bone marrow micronucleus test was investigated in male and female Sprague-Dawley rats. A 42-h
starvation
had a noticeable effect on the ratio of polychromatic to normochromatic erythrocytes (
PCE
and NCE); the values in the starved animals were approx. 77% of the negative controls. An effect of
starvation
on the frequency of micronucleated erythrocytes (MN-E) was not discernable from the results of the present experiment.
...
PMID:Evaluation of the effect of food deprivation on micronucleus test results. 674 Jul 24