Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.23.16 (HIV-1 protease)
2,107 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 169 protease inhibitor 163 Mol 143 Gag 132 NMR 94 gag 83 Pol 81 P2' 71 dimeric 68 pol 57 CD4 51 integrase 45 p24 38 MT-4 26 polypeptide 26 fused 25 SOD 25 renin 25 aspartyl protease 24 Gag polyprotein 23 p66 21 RNase H 20 SAR 20 thrombin 20 ACS 19 GRL 19 cytochrome P450 18 insulin 18 p51 18 hinge 18 P-glycoprotein 17 Boc 16 cathepsin D 16 p17 16 PDB 15 NL4 15 Met 14 dihydrofolate reductase 13 gem 13 p55 12 more...

Disease HIV 1007 immunodeficiency 389 AIDS 292 Human immunodeficiency virus type 29 leukemia 27 cancer 24 SAR 20 lipodystrophy 16 PDB 15 tumor 15 virus infection 14 CEM 14 SARS 12 malaria 11 SDS 11 hepatitis C 10 Rous sarcoma 10 Alzheimer's disease 9 viremia 9 infectious diseases 9 Infection 9 candidiasis 7 influenza 7 hyperlipidemia 7 diabetes 6 fits 6 cytomegalovirus 6 stomatitis 5 vaccinia 5 hypertension 5 dyslipidemia 5 encephalitis 5 West 5 Kaposi's sarcoma 5 NS3 4 Dissociation 4 dementia 4 cataract 4 HTLV-I 4 STD 4 more...

Symptom diarrhea 8 nausea 4 collapse 3 starvation 1 dyspnea 1 general problem 1 acidity 1 vomiting 1 angina 1 abdominal discomfort 1 asthenia 1 weakness 1 splenomegaly 1

Drug Asn 40 Darunavir 32 ROC 23 THF 20 Indinavir 19 AZT 18 AZT 18 ATV 17 Biopolymers 14 TMC114 12 TPV 8 lysine 6 Monit 5 Crixivan 4 Fosamprenavir 4 Crixivan 4 Crixivan 4 Agenerase 3 IL-2 3 NLF 3 Taxol 2 Fosamprenavir calcium 2 ddI 2 Glide 2 ACT 2 Fragment 2 Gel 2 Alanine 2 Norvir 2 Invirase 1 Acacia 1 Fluorescein 1 Rosiglitazone 1 Prezista 1 Compound 19 1 Kenyan 1 Reverset 1 Etravirine 1 Lipidex 1 Trusopt 1 more...

Enzyme HIV-1 protease 2107 reverse transcriptase 220 pepsin 31 renin 25 RNase H 23 trypsin 20 ACS 19 thrombin 19 P-glycoprotein 17 dihydrofolate reductase 15 cathepsin D 15 MDR 12 RNA polymerase 10 lysozyme 9 neuraminidase 9 CYP3A4 9 beta-galactosidase 9 transcriptase 8 protein kinase 8 glutathione S-transferase 7 RNase 7 endothiapepsin 6 elastase 6 subtilisin 6 DNA polymerase 6 ERK 6 RNase 6 endonuclease 5 chymotrypsin 5 proteasome 5 thromboplastin 5 ATPase 5 ribonuclease 5 ribonuclease 5 thymidylate synthase 4 beta-secretase 4 plasmepsin II 4 focal adhesion kinase 4 ricin 3 acetylcholinesterase 3 more...

Compound hydrogen 231 Dec 145 water 134 Asp 82 Phe 75 DNA 67 urea 65 Ile 58 alanine 58 leucine 51 tyrosine 46 Clin 42 arginine 41 oxygen 38 Gly 31 aspartic acid 31 threonine 30 nitrogen 30 aspartic acid 29 NH2 29 aspartic acid 29 aspartic acid 29 THF 27 Ritonavir 26 cysteine 26 hydroxyethylamine 25 salt 23 lysine 23 His 22 methionine 22 KNI-272 21 valine 21 Amprenavir 21 THF 20 ACS 19 AZT 19 ACS 19 Indinavir 19 serine 18 tryptophan 17 more...

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