Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.16 (HIV-1 protease)
 2,107 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 169
protease inhibitor 163
Mol 143
Gag 132
NMR 94
gag 83
Pol 81
P2' 71
dimeric 68
pol 57
CD4 51
integrase 45
p24 38
MT-4 26
polypeptide 26
renin 25
fused 25
SOD 25
aspartyl protease 24
Gag polyprotein 23
more...
Disease
HIV 1007
immunodeficiency 389
AIDS 292
Human immunodeficiency virus type 29
leukemia 27
cancer 24
SAR 20
lipodystrophy 16
PDB 15
tumor 15
CEM 14
virus infection 14
SARS 12
SDS 11
malaria 11
hepatitis C 10
Rous sarcoma 10
Infection 9
Alzheimer's disease 9
infectious diseases 9
more...
Symptom
diarrhea 8
nausea 4
collapse 3
starvation 1
dyspnea 1
general problem 1
acidity 1
vomiting 1
angina 1
abdominal discomfort 1
asthenia 1
weakness 1
splenomegaly 1
Drug
Asn 40
Darunavir 32
ROC 23
THF 20
Indinavir 19
AZT 18
AZT 18
ATV 17
Biopolymers 14
TMC114 12
TPV 8
lysine 6
Monit 5
Fosamprenavir 4
Crixivan 4
Crixivan 4
Crixivan 4
NLF 3
Agenerase 3
IL-2 3
more...
Enzyme
HIV-1 protease 2107
reverse transcriptase 220
pepsin 31
renin 25
RNase H 23
trypsin 20
ACS 19
thrombin 19
P-glycoprotein 17
dihydrofolate reductase 15
cathepsin D 15
MDR 12
RNA polymerase 10
CYP3A4 9
lysozyme 9
neuraminidase 9
beta-galactosidase 9
protein kinase 8
transcriptase 8
glutathione S-transferase 7
more...
Compound
hydrogen 231
Dec 145
water 134
Asp 82
Phe 75
DNA 67
urea 65
Ile 58
alanine 58
leucine 51
tyrosine 46
Clin 42
arginine 41
oxygen 38
aspartic acid 31
Gly 31
nitrogen 30
threonine 30
NH2 29
aspartic acid 29
more...