Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.23.15 (renin)
 35,795 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ZNF554 9.8
renin 9.8
FLJ10761 9.8
renin b 9.8
serpin peptidase inhibitor, clade A, member 8 9.8
C4b-binding protein beta-chain 9.8
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 9.8
ANG-3 9.8
renin binding protein 9.6
RENIN 9.5
renin receptor 9.4
ethanolamine kinase 2 9.2
angiotensinogen 9.2
Angiotensinogen 9.1
Renin 8.8
RENBP 8.8
aminopeptidase O 8.8
ANG-5 8.8
C1orf116 8.8
calneuron 1 8.8
chromosome 9 open reading frame 3 8.8
TGR 8.6
TPRC 8.5
ETNK2 8.5
angiotensin II type 2 receptor 8.3
PRA 8.3
AGTR1 8.3
AngA 8.2
anti-angiotensinogen 8.2
SYDE2 8.2
AT1R 8.2
Aminopeptidase A 8.1
Ang II 8.1
angiotensin receptor 8.1
ATIP1 8.1
angiotensin I converting enzyme 8.0
ACE2 8.0
angiotensin II receptor 7.9
angiotensin II 7.9
UAGT 7.9
ANG 7.9
REN 7.8
aldosterone synthase 7.8
AT1 7.8
carboxymethylenebutenolidase 7.8
PEPP3 7.8
RHBDF1 7.8
receptor-activity-modifying protein 3 7.8
AT1B 7.8
angiotensin-converting enzyme 2 7.8
AGTR2 7.8
aspartyl aminopeptidase 7.7
Angiotensin II receptor 7.7
urinary kallikrein 7.7
THOP1 7.6
HSD11 7.6
AT2 7.6
collectrin 7.6
PRR 7.5
PHA1 7.5
CYP11B2 7.5
CEI 7.5
storkhead box 1 7.5
PZF 7.5
GOLT1A 7.5
3 beta-HSD type II 7.5
ARB1 7.5
dystrophin, muscle 7.5
MP78 7.5
ATRAP 7.4
Angiotensin-converting enzyme 7.4
angiotensin I-converting enzyme 7.4
atrial natriuretic peptide 7.2
alpha-adducin 7.2
PLEKHA6 7.2
diacylglycerol kinase gamma 7.2
ATIP 7.2
ACE 7.1
signal transducer and activator of transcription 2 7.1
SCNN1B 7.1
more...
Disease
PHA2B 9.8
Compensated cirrhosis 9.8
Low-renin essential hypertension 9.8
Acute lead nephropathy 9.8
Asymptomatic cerebrovascular disease 9.8
Feline hypertrophic cardiomyopathy 9.8
leptospirosis kidney 9.8
PHA2C 9.8
PHA2A 9.8
Hyperreninemic hypoaldosteronism 9.5
reninoma 9.4
high renin hypertension 9.3
Residual proteinuria 9.2
renin-dependent hypertension 9.2
hyporeninemic hypoaldosteronism 8.9
Vitamin depletion 8.8
Hypokalemic hypochloremic metabolic alkalosis 8.8
Renal arteritis 8.8
Chronic hyperkalemia 8.8
Unilateral renal artery stenosis 8.7
hypoaldosteronism 8.6
juxtaglomerular cell hyperplasia 8.5
Secondary hyperaldosteronism 8.4
Bilateral renal artery stenosis 8.4
Goldblatt hypertension 8.4
aldosteronism 8.3
Goldblatt 8.3
Diffuse toxic goiter 8.2
Acute nephropathy 8.2
Hypokalemic metabolic alkalosis 8.2
FH II 8.2
acidosis; renal 8.2
Gordon's syndrome 8.1
Renovascular hypertension 8.0
Ask-Upmark kidney 8.0
Glucocorticoid-suppressible hyperaldosteronism 8.0
Liddle's syndrome 7.9
hypokalemic alkalosis 7.9
CMO II deficiency 7.9
Pseudohypoaldosteronism 7.9
acquired hemochromatosis 7.8
Perinatal conditions 7.8
Renal parenchymal disease 7.8
renoprival hypertension 7.8
Renal parenchymal hypertension 7.8
PHA2 7.8
renal hypertension 7.8
Bartter's syndrome 7.6
benign hypertension 7.6
secondary hypertension 7.6
renal artery stenosis 7.5
EPO resistant anemia 7.5
goiter with thyrotoxicosis 7.5
Diuretic abuse 7.5
Cardiac dilatation 7.5
PHA1 7.4
essential hypertension 7.3
17,20-desmolase deficiency 7.3
Acute left ventricular failure 7.3
malignant hypertension 7.3
adrenal hypertension 7.3
Serum potassium increased 7.2
Renal vascular disease 7.2
Chronic lead nephropathy 7.2
Rebound hypertension 7.2
Potassium retention 7.2
Renal sarcoidosis 7.2
renal artery obstruction 7.1
adrenal hyperplasia 7.1
Flash pulmonary edema 7.1
3 beta-HSD deficiency 7.1
adrenal adenoma 7.0
Renal artery dissection 7.0
Aldosteronoma 7.0
Pseudo-Bartter syndrome 7.0
Bladder hypertrophy 7.0
neurogenic hypertension 7.0
uncomplicated hypertension 7.0
Decompensated heart failure 6.9
genetic hypertension 6.9
more...
Symptom
Toxic symptom 9.8
decreased skin turgor 8.2
Macula 6.8
KIDNEY 6.8
absent menses 6.5
Orthostasis 5.7
adipsia 5.4
cardiovascular impairment 5.4
polyuria 5.3
cardiovascular problem 5.3
carpopedal spasm 5.3
Cushingoid 5.2
vasovagal attacks 5.2
Cushingoid 5.2
Poor weight gain 5.2
Watery diarrhea 4.7
hyperosmia 4.7
oliguria 4.5
stomach distension 4.4
Todd's paralysis 4.4
polydipsia 4.3
lassitude 4.2
sinus pressure 4.2
nocturnal polyuria 4.2
Hangover 4.2
Deafferentation 4.0
disturbed balance 4.0
presyncope 3.9
loss of taste 3.8
rales 3.8
tense 3.8
renal pain 3.7
staggering gait 3.7
hypoproteinemia 3.7
Decreased activity 3.5
Behavioral symptoms 3.4
Spotting 3.3
hangover 3.3
Visual disturbances 3.0
excessive sweating 2.9
masculinization 2.9
periorbital edema 2.8
leg cramps 2.6
loin pain 2.5
menopausal symptoms 2.4
Stiffness 2.4
frequent urination 2.4
Neurologic symptoms 2.3
prostration 2.3
skin irritant 2.2
impaired motor coordination 2.2
mastalgia 2.2
dizziness 2.2
cachexia 2.2
Extrapyramidal symptoms 2.2
hypercapnia 2.1
cough 2.1
pedal edema 2.1
inanition 2.0
leg edema 2.0
muscle cramps 2.0
orthopnea 2.0
CSR 1.9
enuresis 1.9
Multimorbidity 1.9
angina 1.9
flank pain 1.9
hypertonia 1.8
tingling 1.8
lightheadedness 1.8
exhaustion 1.8
hot flashes 1.7
overweight 1.7
respiratory distress 1.7
hyperemesis gravidarum 1.7
ketonuria 1.7
non-productive cough 1.7
visual hallucination 1.6
syncope 1.6
flushing 1.6
more...
Drug
Ditekiren 9.8
Cyclic Guanosine Monophosphate 9.8
Terlakiren 9.8
Dilevalol hydrochloride 9.8
Aliskiren 9.6
Guancydine 8.8
Paraaminohippurate 8.8
Ozolinone 8.5
Isorenin 8.5
Saralasin acetate 8.2
Losulazine hydrochloride 8.2
Tasosartan 8.2
Tiamenidine 8.2
Omapatrilat 8.1
Aliskiren fumarate 8.0
Captopril 8.0
Bucindolol hydrochloride 7.8
9 alpha-Fluorocortisol 7.8
Cilazapril 7.7
Alacepril 7.7
Angiotensin II 7.7
Pentolinium 7.7
Micardis 7.7
Pitressin tannate 7.6
Ramipril 7.6
Carperitide 7.5
Conivaptan hydrochloride 7.5
Sandonorm 7.5
Enalaprilat 7.4
Cadralazine 7.3
Enalaprilat 7.3
Lotrel 7.3
Adosterol 7.2
Tenoretic 7.2
Potassium canrenoate 7.2
Olmesartan 7.2
Perindopril 7.2
Valsartan 7.0
Drospirenone 6.9
Pepstatin 6.9
Losartan potassium 6.9
Doca 6.9
Olmesartan Medoxomil 6.9
Ibopamine 6.9
Candoxatril 6.8
Clopamide 6.8
DOCP 6.8
Periactin 6.8
Azosemide 6.8
Aldomet 6.7
Quinaprilat 6.7
Visken 6.7
Enalapril maleate 6.7
Cilnidipine 6.6
Amiloride hydrochloride 6.6
Cortrosyn 6.6
Candoxatril 6.5
Sulotroban 6.5
Cortrosyn 6.4
Bendrofluazide 6.4
Flosequinan 6.4
Kayexalate 6.3
Minipress 6.3
Trandolapril 6.2
Vectarion 6.2
Olmesartan medoxomil 6.2
Fenoldopam 6.1
Hydrochlorothiazide 6.1
Trandate 6.1
Fosinopril sodium 6.1
Torasemide 6.1
Inspra 6.0
Candoxatrilat 6.0
Calcifediol 6.0
Norvasc 6.0
Lacidipine 6.0
Nesiritide 6.0
Indoramin 5.9
Lofexidine 5.8
Trimepranol 5.8
more...
Enzyme
gamma-renin 9.8
N-acyl-D-hexosamine oxidase 9.8
renin 9.8
PRA 8.2
aspartyl aminopeptidase 7.7
angiotensin-converting enzyme 2 7.7
endothiapepsin 7.6
corticosterone methyl oxidase 7.5
aminopeptidase A 7.3
gastricsin 7.2
ACE 7.2
rhizopuspepsin 7.1
KLK13 7.0
AGT 6.8
kallikrein 6.7
steroid 11beta-hydroxylase 6.4
chymase 6.2
carboxypeptidase 1 6.2
aminopeptidase B 5.9
yapsin 1 5.9
penicillopepsin 5.7
tissue kallikrein 5.6
site-1 protease 5.6
neurolysin 5.5
N-acetylglucosamine 2-epimerase 5.5
plasmepsin I 5.5
ADH 5.4
11beta-hydroxysteroid dehydrogenase 5.3
cathepsin D 5.2
25-hydroxyvitamin D3 1alpha-hydroxylase 5.2
N-acetylglucosaminylphosphotransferase 5.0
chymosin 5.0
thimet oligopeptidase 4.9
CD10 4.9
prostasin 4.9
prostaglandin synthetase 4.8
ketopantoate reductase 4.7
20beta-hydroxysteroid dehydrogenase 4.7
proteinase A 4.6
CPN 4.6
MT 1 4.6
site-1 protease 4.6
proteinase A 4.5
21-hydroxylase 4.4
plasmepsin II 4.3
dienelactone hydrolase 4.3
NADPH oxidase 4.3
endothelin-converting enzyme 4.2
SMP 4.2
hydroxyprostaglandin dehydrogenase 4.2
S-adenosylhomocysteine nucleosidase 4.2
NADPH oxidase 4.1
Hageman factor 4.1
pepsin 4.1
UDP-N-acetylglucosamine 2-epimerase 4.1
GPH 4.0
CPA2 4.0
C1 esterase 3.7
cathepsin G 3.7
MAP 3.6
dopamine beta-hydroxylase 3.6
carboxyl proteinase 3.6
oxytocinase 3.5
prolyl endopeptidase 3.5
benzoylformate decarboxylase 3.5
HIV-1 protease 3.4
FPS 3.4
alcohol dehydrogenase 3.3
beta-secretase 3.3
CD13 3.2
NO synthase 3.2
GRK2 3.2
AFR 3.2
PAH 3.1
guanylate cyclase 3.1
HSD 3.1
thromboxane synthase 3.0
GRK5 3.0
3-mercaptopyruvate sulfurtransferase 2.9
PPH 2.9
more...
Compound
Ro 42-5892 9.8
Coronarian 9.8
Teprotide 9.6
Enalkiren 9.5
6-phenylhexanamide 8.8
5-cyclohexylpentanoic acid 8.8
6-cyclohexylhexanoic acid 8.8
6-cyclohexylhexanoic acid 8.8
5-cyclohexylpentanoic acid 8.8
DANU 8.8
aldosterone 8.7
18-Oxocortisol 8.5
Angiotensin I 8.3
21-Deoxycorticosterone 8.2
Fluorohydrocortisone 8.2
TGR 8.1
Eprosartan 8.1
Ang II 7.9
D-Mannosamine 7.8
1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 7.8
Tinoridine 7.8
Quinapril hydrochloride 7.8
CO 11 7.8
UV 1 7.8
C10H14O2 7.8
Benziodarone 7.8
Enalapril 7.7
Angiotensin II 7.7
Losartan 7.6
Candesartan 7.6
Fludrocortisone 7.5
Potassium sulfate 7.5
Potassium sulfate 7.5
Enalaprilat 7.4
5-phenylpentanoic acid 7.4
PD 123177 7.4
Telmisartan 7.3
Perindopril 7.3
Benazepril 7.3
Candesartan cilexetil 7.3
Perindopril erbumine 7.2
2-piperazinone 7.2
2-Bromoethylamine hydrobromide 7.2
2-Bromoethylamine hydrobromide 7.2
Ouabagenin 7.2
Irbesartan 7.2
Angiotensin III 7.2
Navidrex 7.1
Eplerenone 7.1
His-Leu 7.0
Temocaprilat 7.0
benzyl bromoacetate 7.0
[1,1'-biphenyl]-2-carboxylic acid 6.9
PD 123319 6.8
EXP 3174 6.8
18-Hydroxycortisol 6.8
Angiotensin IV 6.8
Fludrocortisone acetate 6.8
11-Dehydrocorticosterone 6.8
Spironolactone 6.8
Penbutolol 6.6
C10H14N2O 6.6
Cyproheptadine hydrochloride 6.6
Paricalcitol 6.6
DTMA 6.6
Quinapril 6.6
octanamide 6.5
Chlorthalidone 6.5
Pepstatin 6.5
LPR 6.5
Canrenone 6.5
Thiazide 6.5
2-phenylalanine 6.4
Minipress 6.3
HNa 6.3
Inactin 6.2
DOCA 6.2
Fosinopril 6.2
2-phenylalanine 6.2
Moexipril 6.2
more...