Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.23.15 (
renin
)
35,795
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
renin
35794
angiotensin II
7818
Ang II
4221
Sep
2269
angiotensinogen
2028
vasopressin
1605
insulin
1601
Renin
1565
ACE
1326
angiotensin receptor
1157
AT1
1156
atrial natriuretic peptide
1118
Mol
1006
ANG
988
angiotensin II receptor
845
bradykinin
736
ACTH
735
kallikrein
633
albumin
621
atrial natriuretic factor
615
calcium channel
575
arginine vasopressin
562
Angiotensin-converting enzyme
551
collagen
540
PRA
533
mineralocorticoid receptor
486
ACE2
426
AT2
413
AT1R
388
natriuretic peptide
387
angiotensin-converting enzyme 2
382
nitric oxide synthase
321
renin receptor
321
endothelin-1
298
neutral endopeptidase
295
beta-endorphin
278
ATPase
277
chronic renal failure
274
prolactin
271
urinary kallikrein
270
more...
Disease
hypertension
12154
essential hypertension
2687
heart failure
2521
diabetes
2333
renal disease
1773
cardiovascular disease
1199
ATM
1157
aldosteronism
1141
proteinuria
1123
congestive heart failure
1117
stroke
992
obesity
870
diabetic nephropathy
797
myocardial infarction
787
renal failure
785
atherosclerosis
716
ventricular hypertrophy
665
type 2 diabetes
635
renal artery stenosis
580
tumor
504
chronic renal failure
430
Conn
417
adenoma
409
cirrhosis
387
glomerulosclerosis
385
SEM
350
ischemia
346
metabolic syndrome
346
hyperglycemia
345
cancer
340
microalbuminuria
305
coronary artery disease
300
dehydration
269
myocardial ischemia
268
SARS
267
secondary hypertension
258
renal insufficiency
244
dyslipidemia
235
Goldblatt
233
preeclampsia
228
more...
Symptom
anesthesia
316
polyuria
138
cough
113
headache
109
weakness
99
overweight
98
angina
87
fatigue
82
pain
82
vomiting
74
respiratory distress
72
dyspnea
62
diarrhea
60
exhaustion
53
dizziness
50
polydipsia
49
oliguria
48
hypercapnia
39
collapse
37
nausea
34
tense
33
seizures
33
syncope
32
cachexia
29
anorexia
25
masculinization
22
flushing
22
analgesia
22
starvation
21
constipation
21
hypothermia
19
thinning
17
abdominal pain
16
hypoproteinemia
16
Macula
15
lethargy
14
chest pain
14
acute stress
13
functional recovery
13
discomfort
12
more...
Drug
Cardiovasc
1291
Angiotensin II
1161
Captopril
647
Nephron
362
Nephron
242
Aliskiren
226
Dial
176
Indomethacin
176
MAP
124
Ramipril
95
lysine
79
nitroglycerin
74
Valsartan
69
Clonidine
61
caffeine
55
Perindopril
53
ETA
51
ROS
48
Atenolol
45
Gel
38
PTH
37
Monit
36
Ouabain
36
Olmesartan
34
Cilazapril
32
Hydrochlorothiazide
31
ICI
31
Asn
29
CSF
29
Enalaprilat
28
Enalaprilat
28
Amiloride
27
Aprotinin
27
Amiloride
24
EE2
22
Omapatrilat
22
Forskolin
21
CaCl2
21
CaCl2
20
CaCl2
20
more...
Enzyme
renin
35795
ACE
3111
kallikrein
725
PRA
540
CD10
331
trypsin
297
ATPase
296
mitogen-activated protein kinase
289
NADPH oxidase
249
angiotensin-converting enzyme 2
235
NADPH oxidase
202
protein kinase C
172
cathepsin D
169
NO synthase
166
pepsin
164
protein kinase
129
ERK
117
chymase
114
superoxide dismutase
111
ADH
105
alcohol dehydrogenase
105
MAP
104
AGT
96
phosphodiesterase
94
guanylate cyclase
81
adenylate cyclase
81
aminopeptidase A
74
catalase
72
tissue kallikrein
70
reverse transcriptase
65
peroxidase
64
prostaglandin synthetase
59
calcineurin
56
tissue plasminogen activator
56
11beta-hydroxysteroid dehydrogenase
56
creatine kinase
53
focal adhesion kinase
52
collagenase
50
RNase
50
RNase
50
more...
Compound
aldosterone
11503
sodium
7372
Clin
4807
water
2950
Dec
2752
salt
2715
potassium
2643
Angiotensin II
2023
Ang II
1828
calcium
1808
acetate
1655
creatinine
1495
glucose
1211
Cardiol
1059
nitric oxide
1017
noradrenaline
949
oxygen
904
ACTH
745
arginine
530
DNA
503
urea
366
Sodium
339
cAMP
327
prostacyclin
327
Losartan
321
PGE2
310
cGMP
279
vitamin D
275
phosphate
242
sodium chloride
240
Salt
221
Adrenal
214
Enalapril
208
His
207
tyrosine
203
nitrogen
200
Phe
200
leucine
185
Insulin
183
Indomethacin
174
more...