Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.23.15 (renin)
35,795 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein renin 35794 angiotensin II 7818 Ang II 4221 Sep 2269 angiotensinogen 2028 vasopressin 1605 insulin 1601 Renin 1565 ACE 1326 angiotensin receptor 1157 AT1 1156 atrial natriuretic peptide 1118 Mol 1006 ANG 988 angiotensin II receptor 845 bradykinin 736 ACTH 735 kallikrein 633 albumin 621 atrial natriuretic factor 615 calcium channel 575 arginine vasopressin 562 Angiotensin-converting enzyme 551 collagen 540 PRA 533 mineralocorticoid receptor 486 ACE2 426 AT2 413 AT1R 388 natriuretic peptide 387 angiotensin-converting enzyme 2 382 nitric oxide synthase 321 renin receptor 321 endothelin-1 298 neutral endopeptidase 295 beta-endorphin 278 ATPase 277 chronic renal failure 274 prolactin 271 urinary kallikrein 270 cytokine 257 GFR 244 proximal tubule 237 ANP 218 Angiotensinogen 211 SARS 208 parathyroid hormone 198 aldosterone synthase 191 cyclooxygenase 182 hemoglobin 180 growth hormone 176 erythropoietin 174 cathepsin D 173 angiotensin I-converting enzyme 169 vascular endothelial growth factor 162 tumor necrosis factor 158 adrenocorticotropic hormone 152 angiotensin I converting enzyme 147 ARB 147 collecting duct 143 TNF 143 beta 1 143 CYP11B2 142 leptin 139 TGR 137 Pol 136 AVP 136 Mal 134 glucagon 133 AMP 132 plasminogen activator inhibitor-1 130 sodium channel 127 AII 124 polypeptide 122 She 121 gut 120 IL-6 117 fibronectin 116 chymase 116 cyclooxygenase-2 116 ATP 114 ADH 105 calcitonin 104 ET-1 104 MAP 104 SBP 103 angiotensin II type 2 receptor 100 C-reactive protein 97 ERK1 97 vitamin D receptor 97 Gen 97 AGT 96 APA 94 phosphodiesterase 93 endoplasmic reticulum 92 serum albumin 92 HDL 90 adiponectin 88 ANF 88 TGF-beta 87 superoxide dismutase 86 vascular endothelium 86 ENaC 86 COX-2 86 interleukin-6 85 p38 84 adrenomedullin 84 DBP 84 endothelial nitric oxide synthase 83 peptidase 82 lipopolysaccharide 81 transforming growth factor-beta 79 PRR 79 substance P 78 BNP 77 tap 76 oxytocin 73 adenylate cyclase 72 peroxisome proliferator-activated receptor 71 membrane-bound 70 AGTR1 69 neuropeptide Y 69 MAPK 69 glycoprotein 68 PRC 65 aspartyl protease 63 matrix metalloproteinase 63 calmodulin 62 endothelin receptor 62 ERK 61 plasminogen activator inhibitor 61 catalase 61 ANOVA 60 NADPH 59 TNF-alpha 59 Angiotensin II receptor 58 PLA 57 somatostatin 57 ETA 57 caspase-3 57 HSD2 56 calcineurin 55 Aminopeptidase A 55 eNOS 54 serine protease 54 bradykinin B2 receptor 54 cytochrome P450 53 MRI 53 mitogen-activated protein 53 adenylyl cyclase 53 inducible nitric oxide synthase 52 thyroid hormone 52 MCP-1 52 fibrinogen 52 CYP11B1 50 Cx40 49 CO2 49 Boc 49 guanylate cyclase 49 monocyte chemoattractant protein-1 49 more...

Disease hypertension 12154 essential hypertension 2687 heart failure 2521 diabetes 2333 renal disease 1773 cardiovascular disease 1199 ATM 1157 aldosteronism 1141 proteinuria 1123 congestive heart failure 1117 stroke 992 obesity 870 diabetic nephropathy 797 myocardial infarction 787 renal failure 785 atherosclerosis 716 ventricular hypertrophy 665 type 2 diabetes 635 renal artery stenosis 580 tumor 504 chronic renal failure 430 Conn 417 adenoma 409 cirrhosis 387 glomerulosclerosis 385 SEM 350 ischemia 346 metabolic syndrome 346 hyperglycemia 345 cancer 340 microalbuminuria 305 coronary artery disease 300 dehydration 269 myocardial ischemia 268 SARS 267 secondary hypertension 258 renal insufficiency 244 dyslipidemia 235 Goldblatt 233 preeclampsia 228 Bartter's syndrome 227 renal hypertension 225 depression 219 NAME 215 acute renal failure 207 cold 191 vascular disease 187 acute myocardial infarction 184 malignant hypertension 180 nephrotic syndrome 174 renal impairment 170 wasting 165 metabolic alkalosis 161 coronary heart disease 156 adrenal hyperplasia 146 anemia 145 type 1 diabetes 144 heart disease 144 hyperinsulinemia 137 glomerulonephritis 136 Cushing's syndrome 135 Alzheimer's disease 131 cardiomyopathy 125 retinopathy 124 plaque 123 pheochromocytoma 123 hypoaldosteronism 120 renal ischemia 118 diabetic retinopathy 114 adrenal adenoma 113 fluid overload 109 glucose intolerance 107 ADH 105 nephrosclerosis 104 vitamin D deficiency 103 dysplasia 102 polycystic kidney 100 hyperlipidemia 100 hypernatremia 94 hypercholesterolemia 91 uterus 89 sepsis 88 portal hypertension 86 hypoglycemia 86 genetic hypertension 86 congenital adrenal hyperplasia 86 Proteinuria 85 IgA nephropathy 84 dementia 84 sepsis 84 systolic hypertension 83 dilated cardiomyopathy 83 Evans 81 pulmonary hypertension 81 APC 81 obstructive sleep apnea 78 carcinoma 78 hydronephrosis 78 hyperparathyroidism 77 Chronic kidney disease (CKD) 73 Goldblatt hypertension 73 nephritis 72 hyperuricemia 70 liver disease 70 adrenal insufficiency 70 hepatorenal syndrome 67 Parkinson's disease 66 HIV 66 Renovascular hypertension 65 hyporeninemic hypoaldosteronism 65 sleep apnea 64 azotemia 64 sympathomimetic 64 osteoporosis 62 antidiuresis 62 uremia 61 borderline hypertension 61 alkalosis 61 pulmonary edema 61 adrenal mass 60 failure to thrive 58 liver fibrosis 58 hypothyroidism 58 hyperthyroidism 57 chronic glomerulonephritis 57 renin-dependent hypertension 57 Liddle's syndrome 56 renal cell carcinoma 56 diabetes insipidus 55 diabetic cardiomyopathy 55 WT1 54 systemic lupus erythematosus 53 hypercalcemia 52 cognitive impairment 51 Blocking 51 aortic stenosis 50 neuropathy 50 cardiovascular risk factor 50 chronic obstructive pulmonary disease 50 breast cancer 49 anuria 48 chronic renal insufficiency 48 SDS 48 arteriosclerosis 47 pyelonephritis 46 GSH 46 malnutrition 46 hypokalemic alkalosis 45 Addison's disease 44 Steroids 44 MAS 44 asthma 43 Addison's disease 43 uncomplicated hypertension 42 renal tubular acidosis 40 glomerulopathy 40 Endothelial dysfunction 40 chronic disease 40 metastases 39 virus infection 39 more...

Symptom anesthesia 316 polyuria 138 cough 113 headache 109 weakness 99 overweight 98 angina 87 pain 82 fatigue 82 vomiting 74 respiratory distress 72 dyspnea 62 diarrhea 60 exhaustion 53 dizziness 50 polydipsia 49 oliguria 48 hypercapnia 39 collapse 37 nausea 34 tense 33 seizures 33 syncope 32 cachexia 29 anorexia 25 analgesia 22 masculinization 22 flushing 22 constipation 21 starvation 21 hypothermia 19 thinning 17 hypoproteinemia 16 abdominal pain 16 Macula 15 chest pain 14 lethargy 14 functional recovery 13 acute stress 13 Ill 12 shortness of breath 12 discomfort 12 discomfort 12 regurgitation 11 hyperoxia 11 sinus pressure 11 sleepiness 11 myalgia 11 rales 10 menopausal symptoms 10 presyncope 10 flank pain 9 adipsia 9 Cushingoid 9 agitation 9 Cushingoid 9 spasm 8 tremor 8 hunger 8 enuresis 7 hypotonia 7 back pain 7 numbness 7 Decreased activity 7 loss of taste 6 lassitude 6 Stiffness 6 excessive sweating 5 tingling 5 cardiovascular impairment 5 hypertonia 5 arthralgia 4 disturbed balance 4 asthenia 4 hemiplegia 4 vertigo 4 insomnia 4 muscle cramps 4 decreased appetite 4 hot flushes 4 chills 4 hangover 4 hot flashes 4 nocturnal polyuria 3 paresthesia 3 decreased skin turgor 3 tachypnea 3 paresis 3 hemoptysis 3 hepatomegaly 3 Neuropathic pain 3 incoordination 3 nausea and vomiting 3 hypocapnia 3 Sedation 3 CSR 3 Deafferentation 3 splenomegaly 3 leg edema 3 dysarthria 3 despair 2 tinnitus 2 blurred vision 2 HSA 2 ketonuria 2 loin pain 2 hypersomnia 2 prostration 2 ataxia 2 erythema 2 periorbital edema 2 carpopedal spasm 2 acidity 2 mastalgia 2 lightheadedness 2 abdominal discomfort 2 orthopnea 2 apathy 2 Welt 2 myoclonus 2 hyperemesis gravidarum 2 exertional dyspnea 2 dysesthesia 2 DNA marker 2 Orthostasis 2 KIDNEY 2 anosmia 2 testicular pain 1 bitter taste 1 Physical findings 1 Poor weight gain 1 visual hallucination 1 productive cough 1 Spotting 1 stomach distension 1 clumsiness 1 staggering gait 1 Hangover 1 stigma 1 blackout 1 frequent urination 1 spasticity 1 Extrapyramidal symptoms 1 hepatosplenomegaly 1 Toxic symptom 1 Watery diarrhea 1 impaired motor coordination 1 Behavioral symptoms 1 acute abdominal pain 1 renal pain 1 orofacial pain 1 exertional angina 1 vasovagal attacks 1 livedo 1 acute pain 1 asynergy 1 atypical chest pain 1 Multimorbidity 1 Neurologic symptoms 1 POA 1 more...

Drug Cardiovasc 1291 Angiotensin II 1161 Captopril 647 Nephron 362 Nephron 242 Aliskiren 226 Indomethacin 176 Dial 176 MAP 124 Ramipril 95 lysine 79 nitroglycerin 74 Valsartan 69 Clonidine 61 caffeine 55 Perindopril 53 ETA 51 ROS 48 Atenolol 45 Gel 38 PTH 37 Ouabain 36 Monit 36 Olmesartan 34 Cilazapril 32 Hydrochlorothiazide 31 ICI 31 Asn 29 CSF 29 Enalaprilat 28 Enalaprilat 28 Aprotinin 27 Amiloride 27 Amiloride 24 Omapatrilat 22 EE2 22 Forskolin 21 CaCl2 21 CaCl2 20 CaCl2 20 Dermatol 19 Portal 19 vitamin E 19 Diurnal 18 Triclosan 18 Phentolamine 17 Albumin 17 Pepstatin 17 Theophylline 17 Ethanol 17 Fenoldopam 15 Fraction 15 Growth hormone 14 Growth hormone 14 Glucagon 14 ascorbate 14 NAG 14 Felodipine 13 Ibopamine 13 Nebivolol 12 Ringer's solution 12 Digitalis 12 CTX 12 Isradipine 12 THF 12 NADH 11 Fructose 10 Drospirenone 10 Xanthium 10 AHF 10 Bosentan 10 Papaverine 10 Cilnidipine 10 Bosentan 10 Trandolapril 10 Timolol 9 Inderal 9 Indapamide 9 Nesiritide 9 Lacidipine 9 MRC 9 Tolvaptan 9 TAK 9 Estrogens 9 ADM 9 Histamine 8 Losartan potassium 8 Glycyrrhiza 8 Guanethidine 8 Indapamide 8 Torasemide 8 Rosiglitazone 8 Sodium nitroprusside 8 ACT 8 Cortrosyn 8 Trilostane 7 Chlorothiazide 7 IL-1ra 7 Terlipressin 7 Kayexalate 7 DDAVP 7 Terlipressin 7 Aliskiren fumarate 7 DMSA 7 Olmesartan medoxomil 7 EPA 7 ABC 7 Nitric Oxide 7 Methyldopa 7 niacin 7 Pitressin 7 DDAVP 7 Alacepril 6 citric acid 6 IL-2 6 Coral 6 DNase I 6 Enalapril maleate 6 Cortrosyn 6 Carbidopa 5 Cicletanine 5 Iloprost 5 CTA 5 Methylprednisolone 5 Glutathione 5 Sinemet 5 Alprenolol 5 Domperidone 5 Flosequinan 5 Lacidipine 5 HCG 5 Pentolinium 5 Adriamycin 5 Photofrin 5 Visken 5 EPI 5 Potassium canrenoate 5 DHT 5 Hypaque 5 MgSO4 5 Micardis 5 ROC 5 Nadolol 5 DHT 5 Pravastatin 5 DFP 4 Tacrolimus 4 Cimetidine 4 BH4 4 Dronedarone 4 KCL 4 Cimetidine 4 lactose 4 Biopolymers 4 Cadralazine 4 Atropine 4 Liraglutide 4 Dihydroergotamine 4 Indoramin 4 Rituximab 4 more...

Enzyme renin 35795 ACE 3111 kallikrein 725 PRA 540 CD10 331 trypsin 297 ATPase 296 mitogen-activated protein kinase 289 NADPH oxidase 249 angiotensin-converting enzyme 2 235 NADPH oxidase 202 protein kinase C 172 cathepsin D 169 NO synthase 166 pepsin 164 protein kinase 129 ERK 117 chymase 114 superoxide dismutase 111 ADH 105 alcohol dehydrogenase 105 MAP 104 AGT 96 phosphodiesterase 94 guanylate cyclase 81 adenylate cyclase 81 aminopeptidase A 74 catalase 72 tissue kallikrein 70 reverse transcriptase 65 peroxidase 64 prostaglandin synthetase 59 tissue plasminogen activator 56 calcineurin 56 11beta-hydroxysteroid dehydrogenase 56 creatine kinase 53 focal adhesion kinase 52 RNase 50 RNase 50 collagenase 50 plasmin 49 chymotrypsin 45 alkaline phosphatase 44 PAH 43 tyrosine hydroxylase 43 NOS 43 caspase-3 42 luciferase 41 phospholipase C 39 CD13 38 thrombin 38 AMP-activated protein kinase 35 phospholipase A2 35 HSD 33 lipoxygenase 30 xanthine oxidase 29 cathepsin B 28 21-hydroxylase 27 proteasome 26 MEK 26 furin 26 phosphatidylinositol 3-kinase 26 cathepsin G 26 HIV-1 protease 25 RNA polymerase 25 lactate dehydrogenase 24 AMPK 23 aspartate aminotransferase 21 urokinase-type plasminogen activator 20 alanine aminotransferase 20 transcriptase 20 glutathione peroxidase 20 endothiapepsin 20 beta-galactosidase 19 dopamine beta-hydroxylase 19 ribonuclease 18 ribonuclease 18 elastase 18 chloramphenicol acetyltransferase 18 chymosin 17 acid phosphatase 17 CYP3A4 16 gastricsin 16 aminopeptidase B 15 acetylcholinesterase 15 AMPK 15 papain 15 thermolysin 14 subtilisin 14 soluble epoxide hydrolase 14 SMP 14 monoamine oxidase 13 MMP 13 endothelin-converting enzyme 13 ACS 12 NADPH-diaphorase 12 CPN 12 succinate dehydrogenase 12 lipoprotein lipase 12 glyceraldehyde-3-phosphate dehydrogenase 12 glutathione S-transferase 11 aldose reductase 11 beta-secretase 10 heme oxygenase 10 Hageman factor 10 thymidine kinase 10 PKG 10 gamma-glutamyl transpeptidase 10 thromboplastin 10 prolyl endopeptidase 10 endonuclease 10 5'-nucleotidase 10 neuraminidase 10 GRK5 10 ornithine decarboxylase 9 CAD 9 CAD 9 phosphoinositide 3-kinase 9 adenosine deaminase 9 adenosine deaminase 9 aspartyl aminopeptidase 9 carbonic anhydrase 9 CAD 9 GRK2 9 glyceraldehyde-3-phosphate dehydrogenase 8 KLK13 8 tryptase 8 AST 8 myosin light chain kinase 8 glyceraldehyde-3-phosphate dehydrogenase 7 3beta-hydroxysteroid dehydrogenase 7 glucose-6-phosphate dehydrogenase 7 glyceraldehyde-3-phosphate dehydrogenase 7 APC 7 thimet oligopeptidase 7 proteinase A 7 lipase 7 penicillopepsin 7 rhizopuspepsin 7 P-glycoprotein 7 CPT 7 glyceraldehyde-3-phosphate dehydrogenase 7 CPT 7 lysozyme 7 interstitial collagenase 7 uricase 6 PARP 6 CPT 6 TdT 6 glutathione reductase 6 PST 6 PCP 6 dipeptidyl peptidase IV 6 caspase-8 6 corticosterone methyl oxidase 6 ceruloplasmin 6 proprotein convertase 6 GSK 6 arginase 6 3-hydroxy-3-methylglutaryl coenzyme A reductase 6 more...

Compound aldosterone 11503 sodium 7372 Clin 4807 water 2950 Dec 2752 salt 2715 potassium 2643 Angiotensin II 2023 Ang II 1828 calcium 1808 acetate 1655 creatinine 1495 glucose 1211 Cardiol 1059 nitric oxide 1017 noradrenaline 949 oxygen 904 ACTH 745 arginine 530 DNA 503 urea 366 Sodium 339 cAMP 327 prostacyclin 327 Losartan 321 PGE2 310 cGMP 279 vitamin D 275 phosphate 242 sodium chloride 240 Salt 221 Adrenal 214 Enalapril 208 His 207 tyrosine 203 Phe 200 nitrogen 200 leucine 185 Insulin 183 Dial 174 Indomethacin 174 Propranolol 163 Ile 160 DOCA 159 Propranolol 159 alanine 153 sulfate 150 TNF 143 hydrogen 141 lysine 140 AMP 140 TGR 137 Isoproterenol 132 Salix 129 serine 122 Norepinephrine 120 ATP 115 CO2 114 Asp 113 ethanol 111 MAP 105 alcohol dehydrogenase 105 galactose 102 nitrate 102 PGE 101 Angiotensin I 96 zinc 95 EDTA 94 EDTA 94 Pac 94 Telmisartan 91 GMP 90 Spironolactone 90 Vitamin D 89 Nifedipine 88 5-HT 86 DBP 85 proline 84 Dopamine 84 DBP 84 Vasopressin 83 Candesartan 83 PAC 81 ammonium 78 BNP 78 Cortisol 77 phosphorus 77 threonine 72 Estrogen 71 DOC 69 His-Leu 67 Adenosine 63 iron 62 prostaglandin F1 60 NADPH 59 NADPH 59 PEG 58 cysteine 58 LPR 57 carbonate 55 Bradykinin 55 caffeine 55 methionine 54 NH2 54 silver 54 SDS 53 Dexamethasone 51 Perindopril 51 ETA 50 STZ 50 prostaglandin E1 49 PAH 48 glycerol 48 Hydrochlorothiazide 48 nicotinamide 46 HCl 45 Irbesartan 45 Verapamil 44 Prazosin 44 Cyclosporine 44 glutamate 42 Gly 42 Kallikrein 42 Thiazide 40 Estrogen 40 GSH 40 homocysteine 40 GSH 40 Trypsin 39 Verapamil 39 formaldehyde 39 DEAE 39 PD 123319 38 isoleucine 37 tryptophan 37 Ouabain 36 Mg2+ 35 Optimal 35 ADP 35 TSH 35 DTPA 34 iodine 34 isoleucine 33 Eplerenone 32 Hydralazine 31 ICI 31 Diabetol 30 ADP 30 ADP 30 Enalaprilat 30 tryptophan 30 tryptophan 29 Hoe 29 valine 29 tryptophan 29 DBA 28 DBA 28 N-acetylcysteine 28 DBA 28 ASA 28 more...

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