EC:3.4.22.B10 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:3.4.22.B10 (caspase-7)
896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
caspase-3	538
caspase-9	229
PARP	159
Bcl-2	148
caspase-8	143
cytochrome c	109
p53	94
Mol	88
poly(ADP-ribose) polymerase	63
Sep	59
endoplasmic reticulum	57
p21	48
Fas	44
Bid	40
annexin V	37
caspase 7	36
p38	34
inhibitor of apoptosis	32
XIAP	30
JNK	27
ERK	26
poly (ADP-ribose) polymerase	25
calpain	25
bax	24
TNF	23
survivin	21
cyclin D1	21
Bak	21
MAPK	20
p27	20
AKT	20
CHOP	20
GRP78	20
cytokine	20
bcl-2	19
ERK1	18
Smac	18
Apaf-1	17
ATP	16
ADP	16
Mcl-1	16
mTOR	16
LC3	16
glucose-regulated protein	15
ROS	14
PARP-1	14
proteasome	14
FasL	13
Tumor necrosis factor	13
PERK	12
c-Jun	12
Fas ligand	12
CDK2	12
estrogen receptor	11
tumor necrosis factor	11
X-linked inhibitor of apoptosis protein	11
apoptosis-inducing factor	11
p65	11
granzyme B	11
MEK	10
cytochrome	10
anti-apoptotic protein	10
cIAP2	10
NMR	10
IAP2	10
CDK6	10
pro-apoptotic protein	10
tyrosine kinase	10
DIABLO	10
histone deacetylase	10
FADD	9
CDK4	9
PC-3	9
PI3K	9
cyclin A	9
proliferating cell nuclear antigen	9
catalase	9
ubiquitin	8
epidermal growth factor receptor	8
interferon	8

Disease
cancer	256
tumor	149
MCF	119
breast cancer	105
carcinoma	33
tumor growth	30
colon cancer	27
leukemia	24
hepatocellular carcinoma	23
carcinogenesis	22
prostate cancer	20
B-cell lymphoma	19
lung cancer	18
colorectal cancer	17
glioma	17
adenocarcinoma	17
tumorigenesis	15
Alzheimer's disease	12
squamous cell carcinoma	12
ischemia	12
lymphoma	11
neuroblastoma	10
melanoma	10
acute myeloid leukemia	9
tumor progression	9
pancreatic cancer	9
gastric cancer	9
Blocking	8
renal cell carcinoma	8
liver cancer	8
non-small cell lung cancer	8
cervical cancer	8
esophageal cancer	7
GSH	7
esophageal cancer	7
retinoblastoma	7
Parkinson's disease	6
liver cancer	6
stroke	6
Kaposi's sarcoma	6
multiple myeloma	6
infectious diseases	5
solid tumor	5
glioblastoma	5
influenza	5
Legionella	5
skin cancer	5
ovarian cancer	5
acute promyelocytic leukemia	5
bladder cancer	5
MTS	5
AGS	5
DDP	5
chronic myeloid leukemia	4
glioblastoma multiforme	4
hepatitis C	4
epithelial ovarian cancer	4
Hepatocellular carcinoma	4
diabetes	4
lung carcinoma	4
fibrosarcoma	4
virus infection	4
myocardial ischemia	4
amyotrophic lateral sclerosis	3
Huntington's disease	3
metastases	3
liver fibrosis	3
HIV	3
cerebral ischemia	3
sepsis	3
pneumonia	3
hepatitis	3
myocardial infarction	3
Infection	3
osteosarcoma	3
NOD	3
muscular atrophy	3
heart failure	3
sepsis	3
pheochromocytoma	3

Enzyme
caspase-7	896
caspase-7	896
caspase-3	532
caspase-9	225
PARP	172
caspase-8	138
mitogen-activated protein kinase	75
caspase-6	68
caspase-6	68
caspase-1	46
caspase-2	38
caspase-2	38
ERK	34
protein kinase	18
MEK	14
proteasome	14
cdc2	12
protein kinase C	12
granzyme B	11
caspase-4	11
caspase-4	11
focal adhesion kinase	10
catalase	9
superoxide dismutase	9
lactate dehydrogenase	7
MAP	6
ACS	6
glutathione peroxidase	5
GSK	5
caspase-10	5
glutathione S-transferase	5
caspase-10	5
glutathione reductase	4
AMP-activated protein kinase	4
NADPH oxidase	4
endonuclease	4
RNase	4
aspartate aminotransferase	4
alanine aminotransferase	4
ATPase	4
luciferase	4
trypsin	4
caspase-11	3
myosin light chain kinase	3
NADPH oxidase	3
phosphoinositide 3-kinase	3
cathepsin G	3
caspase-11	3
RNase	3
elastase	3
creatine kinase	3
phospholipase C	3
DNase	3
calcineurin	3
cathepsin D	3
ECH	3
Omi/HtrA2	3
reverse transcriptase	3
m-calpain	3
topoisomerase	3
thrombin	3
topoisomerase	3
peroxiredoxin	2
AMPK	2
NQO1	2
P-glycoprotein	2
thymidylate synthase	2
succinate dehydrogenase	2
CAD	2
complex I	2
DNA polymerase	2
DNA methyltransferase	2
caspase-5	2
sphingosine kinase	2
prolyl hydroxylase	2
CAD	2
mu-calpain	2
cathepsin B	2
IKK	2
AMPK	2