Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.B10 (caspase-7)
 896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 538
caspase-9 229
PARP 159
Bcl-2 148
caspase-8 143
cytochrome c 109
p53 94
Mol 88
poly(ADP-ribose) polymerase 63
Sep 59
endoplasmic reticulum 57
p21 48
Fas 44
Bid 40
annexin V 37
caspase 7 36
p38 34
inhibitor of apoptosis 32
XIAP 30
JNK 27
ERK 26
calpain 25
poly (ADP-ribose) polymerase 25
bax 24
TNF 23
cyclin D1 21
survivin 21
Bak 21
MAPK 20
CHOP 20
p27 20
cytokine 20
GRP78 20
AKT 20
bcl-2 19
Smac 18
ERK1 18
Apaf-1 17
LC3 16
ATP 16
more...
Disease
cancer 256
tumor 149
MCF 119
breast cancer 105
carcinoma 33
tumor growth 30
colon cancer 27
leukemia 24
hepatocellular carcinoma 23
carcinogenesis 22
prostate cancer 20
B-cell lymphoma 19
lung cancer 18
adenocarcinoma 17
glioma 17
colorectal cancer 17
tumorigenesis 15
ischemia 12
Alzheimer's disease 12
squamous cell carcinoma 12
lymphoma 11
neuroblastoma 10
melanoma 10
pancreatic cancer 9
gastric cancer 9
acute myeloid leukemia 9
tumor progression 9
liver cancer 8
renal cell carcinoma 8
Blocking 8
non-small cell lung cancer 8
cervical cancer 8
GSH 7
esophageal cancer 7
esophageal cancer 7
retinoblastoma 7
stroke 6
Parkinson's disease 6
Kaposi's sarcoma 6
multiple myeloma 6
more...
Symptom
starvation 3
seizures 2
functional recovery 2
hypothermia 1
hypercapnia 1
hyperoxia 1
pain 1
headache 1
neuralgia 1
erythema 1
Drug
ROS 14
lysine 8
MAP 6
IFN-gamma 4
Arsenic trioxide 4
Taxol 3
Sorafenib 3
IL-2 3
AMC 2
IFN-beta 2
ZnO 2
Dermatol 2
ICI 2
NVP 2
Fulvestrant 1
Cardiovasc 1
Compound 18 1
CPT-11 1
Estrogens 1
CTX 1
Clopidogrel 1
Ketoconazole 1
Purvalanol 1
PFT 1
Epigallocatechin 1
Biopolymers 1
Adriamycin 1
Phosphatidylserine 1
TFT 1
Rosiglitazone 1
Monit 1
Nitric Oxide 1
Monensin 1
Lovastatin 1
FAD 1
Nephron 1
Parkin 1
Propofol 1
Asn 1
Simvastatin 1
more...
Enzyme
caspase-7 896
caspase-7 896
caspase-3 532
caspase-9 225
PARP 172
caspase-8 138
mitogen-activated protein kinase 75
caspase-6 68
caspase-6 68
caspase-1 46
caspase-2 38
caspase-2 38
ERK 34
protein kinase 18
MEK 14
proteasome 14
protein kinase C 12
cdc2 12
granzyme B 11
caspase-4 11
caspase-4 11
focal adhesion kinase 10
catalase 9
superoxide dismutase 9
lactate dehydrogenase 7
MAP 6
ACS 6
glutathione peroxidase 5
caspase-10 5
GSK 5
glutathione S-transferase 5
caspase-10 5
NADPH oxidase 4
alanine aminotransferase 4
endonuclease 4
glutathione reductase 4
aspartate aminotransferase 4
AMP-activated protein kinase 4
ATPase 4
trypsin 4
more...
Compound
DNA 152
Dec 74
oxygen 69
cysteine 41
Asp 38
MDA 34
MTT 33
ADP-ribose 26
glucose 23
TNF 23
calcium 20
ADP 18
iodine 17
ADP 16
dUTP 16
ADP 16
ATP 16
tyrosine 15
alanine 14
sodium 13
bromide 13
serine 12
hydrogen 10
N-acetylcysteine 10
MEK 10
lysine 9
water 8
zinc 8
Clin 8
acridine 8
Hoechst 33342 8
GSH 7
aspartic acid 7
aldehyde 7
aspartic acid 7
ethyl acetate 7
GSH 7
dATP 7
boron 7
aspartic acid 7
more...