Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.B10 (caspase-7)
 896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 538
caspase-9 229
PARP 159
Bcl-2 148
caspase-8 143
cytochrome c 109
p53 94
Mol 88
poly(ADP-ribose) polymerase 63
Sep 59
endoplasmic reticulum 57
p21 48
Fas 44
Bid 40
annexin V 37
caspase 7 36
p38 34
inhibitor of apoptosis 32
XIAP 30
JNK 27
ERK 26
poly (ADP-ribose) polymerase 25
calpain 25
bax 24
TNF 23
cyclin D1 21
Bak 21
survivin 21
p27 20
GRP78 20
cytokine 20
AKT 20
MAPK 20
CHOP 20
bcl-2 19
ERK1 18
Smac 18
Apaf-1 17
mTOR 16
LC3 16
ATP 16
Mcl-1 16
ADP 16
glucose-regulated protein 15
proteasome 14
ROS 14
PARP-1 14
FasL 13
Tumor necrosis factor 13
c-Jun 12
CDK2 12
Fas ligand 12
PERK 12
tumor necrosis factor 11
X-linked inhibitor of apoptosis protein 11
estrogen receptor 11
apoptosis-inducing factor 11
p65 11
granzyme B 11
tyrosine kinase 10
NMR 10
IAP2 10
cIAP2 10
pro-apoptotic protein 10
MEK 10
DIABLO 10
histone deacetylase 10
cytochrome 10
CDK6 10
anti-apoptotic protein 10
PI3K 9
catalase 9
PC-3 9
FADD 9
cyclin A 9
CDK4 9
proliferating cell nuclear antigen 9
epidermal growth factor receptor 8
p38 mitogen-activated protein kinase 8
C/EBP homologous protein 8
interferon 8
collagen 8
cyclin E 8
CD95 8
Ki-67 8
ubiquitin 8
cyclin 7
IL-6 7
lactate dehydrogenase 7
dimeric 7
histone 7
GSH 7
PKC 7
p23 7
IL-8 7
TNF-alpha 7
PC3 7
proteasome inhibitor 7
cyclin B1 7
superoxide dismutase 7
HSP70 7
MEK1 6
LDH 6
p62 6
p20 6
DR5 6
Beclin-1 6
PTEN 6
ATF6 6
polypeptide 6
cysteine protease 6
H2AX 6
DR4 6
TdT 6
MAP 6
BiP 6
IAP 6
Bax protein 6
heat shock protein 6
lipopolysaccharide 6
ACS 6
caspase 6 6
SOD 6
ICAD 6
BAX 6
NLRC4 6
IFN 5
glial fibrillary acidic protein 5
ATF4 5
EGFR 5
extracellular signal-regulated kinase 5
TRAIL-R1 5
Poly 5
AIF 5
cyclin-dependent kinase 5
glutathione peroxidase 5
GSK 5
LPS 5
Chk1 5
Caspase-1 5
CD40 5
MTS 5
AGS 5
ASC 5
p35 4
ESI 4
gasdermin D 4
c-Myc 4
p38MAPK 4
E2F1 4
CCAAT/enhancer-binding protein homologous protein 4
CASP7 4
MMP9 4
serum albumin 4
inducible nitric oxide synthase 4
catenin 4
BCL2 4
perforin 4
amyloid precursor protein 4
HDAC 4
ATF 4
STAT3 4
JNK1 4
Histone deacetylase 4
UTR 4
p12 4
lymphoid 4
glutathione reductase 4
TRAIL 4
Cytokine 4
BAD 4
VEGFR2 4
BRAF 4
insulin 4
TLR4 4
IRE1 4
caspase 2 4
PUMA 4
IFN-gamma 4
Hsp90 4
5-lipoxygenase 4
p18 4
PKR 4
ataxin-7 4
Cytochrome c 4
PARP1 4
p17 4
CPP32 4
35 kDa 4
CD95L 4
brain-derived neurotrophic factor 4
IL-18 4
ACHN 4
endonuclease 4
mitogen-activated protein 4
TLR2 4
ATPase 4
cathepsin G 4
Bcl-X 4
VEGF 3
IL-2 3
p21 protein 3
BID 3
neuronal apoptosis inhibitory protein 3
HDAC1 3
HER2 3
PKB 3
eukaryotic translation initiation factor 3
RNase 3
cathepsin D 3
IL-15 3
cyclooxygenase 2 3
p10 3
cyclin dependent kinase 3
P21 3
glutathione S-transferase 3
WAF1 3
phosphoinositide 3-kinase 3
claudin-12 3
BAK 3
DNase 3
manganese superoxide dismutase 3
LC3B 3
interleukin-6 3
BOD 3
huntingtin 3
mdm2 3
IRF-1 3
bcl-x 3
TNF-R1 3
osteosarcoma 3
c-myc 3
protein disulfide isomerase 3
kit 3
HDAC3 3
endonuclease G 3
Pseudomonas 3
IkappaBalpha 3
FOXO3 3
glycoprotein 3
occludin 3
MDM2 3
Raji 3
aspartate aminotransferase 3
plasminogen 3
FLIP 3
aromatase 3
NOD 3
apoptosis inhibitor 3
carp 3
IRE 3
X-chromosome 3
rhodopsin 3
matrix metalloproteinase 3
lamin A 3
XBP1 3
phosphatase and tensin homolog 3
LOX 3
DNA damage-inducible protein 3
protein phosphatase 3
IL-1 3
calmodulin 3
serine/threonine kinase 3
p42 3
cyclooxygenase-2 3
ankyrin 3
tumor necrosis factor receptor 3
extracellular signal-regulated kinase 1 3
NF-E2-related factor 2 3
fibronectin 3
MAP kinase 3
Spinocerebellar ataxia type 7 3
ATG5 3
calreticulin 3
protein kinase inhibitor 3
NEDD8 3
MMP-2 3
collecting duct 3
serine protease 3
thrombin 3
A431 3
cIAP1 3
E-cadherin 3
reductase 3
GADD45 3
MOLT 3
microsomal 3
vascular endothelial growth factor receptor 3
calpastatin 3
Bik 3
calnexin 3
RhoA 3
NADPH 3
GM-CSF 2
amyloid beta 2
PI-3 kinase 2
12-LOX 2
thrombopoietin 2
p44 2
CDC2 2
metallopeptidase 2
all-trans 2
interferon regulatory factor-1 2
Rho 2
gut 2
kappa-casein 2
MMP-9 2
PAK2 2
c-myc mRNA 2
p19 2
FAM 2
SMA 2
phospholipase 2
GIRK2 2
lamin A/C 2
XBP-1 2
GRP 2
cyclin-dependent kinase inhibitor 2
Kir6.2 2
galactosamine 2
more...
Disease
cancer 256
tumor 149
MCF 119
breast cancer 105
carcinoma 33
tumor growth 30
colon cancer 27
leukemia 24
hepatocellular carcinoma 23
carcinogenesis 22
prostate cancer 20
B-cell lymphoma 19
lung cancer 18
colorectal cancer 17
adenocarcinoma 17
glioma 17
tumorigenesis 15
Alzheimer's disease 12
squamous cell carcinoma 12
ischemia 12
lymphoma 11
neuroblastoma 10
melanoma 10
acute myeloid leukemia 9
tumor progression 9
pancreatic cancer 9
gastric cancer 9
cervical cancer 8
non-small cell lung cancer 8
liver cancer 8
renal cell carcinoma 8
Blocking 8
GSH 7
esophageal cancer 7
esophageal cancer 7
retinoblastoma 7
stroke 6
Parkinson's disease 6
liver cancer 6
multiple myeloma 6
Kaposi's sarcoma 6
infectious diseases 5
solid tumor 5
glioblastoma 5
MTS 5
bladder cancer 5
influenza 5
ovarian cancer 5
skin cancer 5
Legionella 5
DDP 5
AGS 5
acute promyelocytic leukemia 5
diabetes 4
glioblastoma multiforme 4
lung carcinoma 4
virus infection 4
Hepatocellular carcinoma 4
chronic myeloid leukemia 4
fibrosarcoma 4
epithelial ovarian cancer 4
hepatitis C 4
myocardial ischemia 4
metastases 3
liver fibrosis 3
amyotrophic lateral sclerosis 3
sepsis 3
pheochromocytoma 3
endometrial cancer 3
pneumonia 3
heart failure 3
sepsis 3
muscular atrophy 3
NOD 3
Infection 3
osteosarcoma 3
myocardial infarction 3
Huntington's disease 3
hepatitis 3
HIV 3
cerebral ischemia 3
cold 2
medulloblastoma 2
chronic lymphocytic leukemia 2
myeloid leukemia 2
herpes simplex 2
hyperosmolality 2
ABL 2
aggressiveness 2
Pineal 2
Primary effusion lymphoma 2
Leukemia 2
cirrhosis 2
mammary tumor 2
fatty liver 2
mesothelioma 2
hypoglycemia 2
head and neck cancer 2
APC 2
salmonellosis 2
HCC 2
stomatitis 2
papillary thyroid cancer 2
acute renal failure 2
retinitis pigmentosa 2
coronary artery disease 2
Melanoma 2
cholera 2
diabetic retinopathy 2
AIDS 2
acute myocardial infarction 2
herpes 2
Glioblastoma 2
Hippel 2
arthritis 2
chronic lymphocytic leukemia 2
acute lymphoblastic leukemia 2
hypertension 2
rheumatoid arthritis 2
oral cancer 2
cowpox 2
cardiovascular disease 2
primary tumor 2
systemic lupus erythematosus 2
thyroid cancer 2
metastatic breast cancer 2
DMS 2
brain tumor 2
ductal carcinoma 2
epilepsy 2
ATM 2
brain cancer 2
atherosclerosis 2
Aleutian disease 1
lupus 1
autoimmune disease 1
malignant mesothelioma 1
infertility 1
stromal tumors 1
Pancreas 1
Cryptococcus neoformans 1
dementia 1
male infertility 1
SCID 1
inflammatory bowel disease 1
renal failure 1
bacterial infection 1
parkinsonism 1
DWI 1
Reovirus infection 1
gastrointestinal stromal tumor 1
plaque 1
uveitis 1
premature ovarian failure 1
Neuroblastoma 1
abortion 1
hematologic malignancies 1
vaccinia 1
MICA 1
Foot-and-mouth disease 1
sleep apnea 1
SDS 1
avian influenza 1
metastatic melanoma 1
Autism 1
ovarian neoplasm 1
non-Hodgkin's lymphoma 1
CHN 1
Hodgkin's disease 1
renal ischemia 1
DBM 1
adenoma 1
mental retardation 1
scurvy 1
amok 1
dyskinesia 1
essential hypertension 1
Chondrosarcoma 1
graft-versus-host disease 1
Adhesion 1
Autism spectrum disorder 1
dysplasia 1
Chondrosarcoma 1
viremia 1
ICP 1
liver disease 1
malaria 1
ear disease 1
metabolic syndrome 1
NS3 1
hormone refractory prostate cancer 1
scleroderma 1
prostatic disease 1
MAS 1
Medulloblastoma 1
keratosis 1
Chlamydia 1
drug withdrawal 1
proteinuria 1
WRN 1
FAS 1
osteoarthritis 1
renal disease 1
bone cancer 1
obstructive sleep apnea 1
PCD 1
coronary occlusion 1
hyperglycemia 1
TAS 1
TEM 1
Pancreas 1
pertussis 1
renal cyst 1
ventricular hypertrophy 1
malnutrition 1
polycystic kidney 1
TEM 1
Crohn's disease 1
cytomegalovirus 1
multiple sclerosis 1
occupational disease 1
sarcoma 1
primary pulmonary hypertension 1
subacute sclerosing panencephalitis 1
suicide 1
LAP 1
adenocarcinoma of the lung 1
cognitive impairment 1
Testicular Cancer 1
AO2 1
immunodeficiency 1
encephalomyelitis 1
FBS 1
chondrosarcoma 1
mole 1
residual disease 1
stage III endometrial cancer 1
myelitis 1
TAM 1
aggression 1
Proteinuria 1
memory impairment 1
chronic obstructive pulmonary disease 1
carcinoma in situ 1
endometritis 1
gastrointestinal cancer 1
Colon cancer 1
Epstein 1
Giant cell tumor of bone 1
Ewing's sarcoma 1
Neuroblastoma 1
autism 1
uterus 1
Syndrome 1
AIN 1
STS 1
B-cell lymphomas 1
testicular cancer 1
myositis 1
rare disease 1
lymphosarcoma 1
Chagas 1
Ureteral obstruction 1
enterocolitis 1
glomerulopathy 1
acute pancreatitis 1
lupus 1
ICS 1
multiple disorders 1
liver metastases 1
laryngeal squamous cell carcinoma 1
endotoxic shock 1
HSP 1
hepatitis B 1
achromatopsia 1
Esophageal squamous cell carcinoma 1
Cushing's disease 1
mastitis 1
diabetic cardiomyopathy 1
diphtheria 1
OHD 1
mental retardation 1
fits 1
CEM 1
MDD2 1
mole 1
periodontitis 1
Symptom
starvation 3
seizures 2
functional recovery 2
hypothermia 1
hypercapnia 1
hyperoxia 1
pain 1
headache 1
neuralgia 1
erythema 1
Drug
ROS 14
lysine 8
MAP 6
IFN-gamma 4
Arsenic trioxide 4
Taxol 3
IL-2 3
Sorafenib 3
AMC 2
IFN-beta 2
ICI 2
ZnO 2
Dermatol 2
NVP 2
Fulvestrant 1
Cardiovasc 1
Compound 18 1
CPT-11 1
Estrogens 1
CTX 1
Clopidogrel 1
Rituximab 1
Spiegel 1
Nephron 1
vitamin E 1
K-252a 1
Biopolymers 1
Adriamycin 1
Glycyrrhiza 1
TFT 1
Nitric Oxide 1
Monensin 1
Lovastatin 1
FAD 1
Purvalanol 1
Amiloride 1
Ketoconazole 1
Monit 1
Silica gel 1
Epigallocatechin 1
PFT 1
TTC 1
Nephron 1
Parkin 1
Pravastatin 1
Phosphatidylserine 1
Rosiglitazone 1
CSF 1
Propofol 1
caffeine 1
-deoxyadenosine 1
Parkin 1
Simvastatin 1
Asn 1
Herceptin 1
Fragment 1
Bortezomib 1
Propidium 1
ADR 1
Enzyme
caspase-7 896
caspase-7 896
caspase-3 532
caspase-9 225
PARP 172
caspase-8 138
mitogen-activated protein kinase 75
caspase-6 68
caspase-6 68
caspase-1 46
caspase-2 38
caspase-2 38
ERK 34
protein kinase 18
proteasome 14
MEK 14
cdc2 12
protein kinase C 12
caspase-4 11
granzyme B 11
caspase-4 11
focal adhesion kinase 10
catalase 9
superoxide dismutase 9
lactate dehydrogenase 7
ACS 6
MAP 6
GSK 5
glutathione peroxidase 5
caspase-10 5
glutathione S-transferase 5
caspase-10 5
glutathione reductase 4
AMP-activated protein kinase 4
RNase 4
aspartate aminotransferase 4
endonuclease 4
alanine aminotransferase 4
ATPase 4
luciferase 4
trypsin 4
NADPH oxidase 4
caspase-11 3
calcineurin 3
NADPH oxidase 3
thrombin 3
DNase 3
cathepsin G 3
RNase 3
myosin light chain kinase 3
elastase 3
ECH 3
creatine kinase 3
cathepsin D 3
m-calpain 3
phospholipase C 3
Omi/HtrA2 3
topoisomerase 3
phosphoinositide 3-kinase 3
caspase-11 3
topoisomerase 3
reverse transcriptase 3
AMPK 2
NQO1 2
P-glycoprotein 2
thymidylate synthase 2
succinate dehydrogenase 2
complex I 2
CAD 2
CAD 2
DNA methyltransferase 2
DNA polymerase 2
caspase-5 2
sphingosine kinase 2
IKK 2
CAD 2
prolyl hydroxylase 2
mu-calpain 2
peroxiredoxin 2
AMPK 2
aspartase 2
cathepsin B 2
legumain 2
caspase-5 2
cathepsin L 1
demethylase 1
cathepsin C 1
polo-like kinase 1 1
ACE 1
ribonuclease 1
deoxycytidine kinase 1
MEKK1 1
firefly luciferase 1
RNase T1 1
neutrophil elastase 1
PTPase 1
ribonuclease 1
SNO 1
MAT 1
glyceraldehyde-3-phosphate dehydrogenase 1
lysozyme 1
beta-glucosidase 1
beta-glucosidase 1
AST 1
subtilisin 1
APC 1
Tpa 1
lipase 1
urokinase-type plasminogen activator 1
prostate-specific antigen 1
MAT 1
TSP-1 1
stromelysin-3 1
Alternating 1
ALDH 1
PHT 1
arginase 1
thermolysin 1
MDR 1
collagenase 1
monoamine oxidase 1
diamine oxidase 1
phosphatidylinositol 3-kinase 1
acetylcholinesterase 1
peroxidase 1
TdT 1
HSD 1
lipoxygenase 1
MPP 1
cathepsin K 1
chitinase 1
adenosine kinase 1
Compound
DNA 152
Dec 74
oxygen 69
cysteine 41
Asp 38
MDA 34
MTT 33
ADP-ribose 26
TNF 23
glucose 23
calcium 20
ADP 18
iodine 17
dUTP 16
ADP 16
ATP 16
ADP 16
tyrosine 15
alanine 14
sodium 13
bromide 13
serine 12
hydrogen 10
MEK 10
N-acetylcysteine 10
lysine 9
Clin 8
acridine 8
zinc 8
water 8
Hoechst 33342 8
aldehyde 7
aldehyde 7
dATP 7
ethyl acetate 7
GSH 7
aspartic acid 7
aspartic acid 7
aspartic acid 7
boron 7
GSH 7
aspartic acid 7
ACS 6
nitrogen 6
ethanol 6
ACS 6
MAP 6
glutamate 6
kaempferol 5
ASC 5
copper 5
Acrolein 5
Curcumin 5
chalcone 5
leucine 5
threonine 5
MTS 5
Paclitaxel 4
H2O2 4
phosphate 4
NH2 4
Cytochrome c 4
arginine 4
galactose 4
DDP 4
glutamic acid 4
ATF 4
Cordycepin 3
Cer 3
Isoliquiritigenin 3
Cordycepin 3
potassium 3
Melatonin 3
NAD 3
COS 3
indole-3-carbinol 3
anthracene 3
iron 3
valine 3
methionine 3
Cordycepin 3
sulfate 3
selenium 3
Phe 3
glutamine 3
NADPH 3
DMSO 3
NADPH 3
5-FU 3
acetate 3
HMG-CoA 2
Staurosporine 2
NAD 2
DBA 2
tert-butyl hydroperoxide 2
AMP 2
Neuronal 2
DMI 2
Estrogen 2
fluorine 2
Rottlerin 2
Propofol 2
COX 2
cGMP 2
DMS 2
pyrene 2
Ribose 2
cyanide 2
Adriamycin 2
ammonium 2
DMI 2
Wortmannin 2
CO2 2
acetic acid 2
ADR 2
Pac 2
naphthoquinone 2
Panam 2
naphthoquinone 2
Rottlerin 2
naphthoquinone 2
retinoic acid 2
naphthoquinone 2
Estrogen 2
Foscan 2
DPPH 2
nitric oxide 2
PEG 2
nickel 2
naphthoquinone 2
naphthoquinone 2
silver 2
THP 2
C-3 2
MSM 2
TNM 2
XTT 2
BCR 2
salt 2
His 2
5-HETE 2
naphthalene 2
benzene 2
THP 2
ICI 2
naphthoquinone 2
Oridonin 2
methanol 2
Quercetin 2
ABL 2
Rottlerin 2
Ile 2
pyridine 2
VP-16 2
Staurosporine 2
12(S)-HETE 1
DNP 1
Cap 1
Dexamethasone 1
hydroxide 1
formic acid 1
formic acid 1
Acacetin 1
PEG 1
Serine 1
Chloroquine 1
DPI 1
Decursin 1
Bisphenol A 1
Cholesterol 1
chromate 1
6-Hydroxydopamine 1
CTX 1
2,6-diisopropylphenyl 1
TOF 1
MPT 1
CUE 1
Nitrite 1
DCB 1
APO 1
RELA 1
Phenylephrine 1
2-butenyl 1
AFC 1
tryptophan 1
TPCK 1
Safranin O 1
Dopamine 1
CPT-11 1
Fisetin 1
Crocin 1
beta-Lapachone 1
hydroquinone 1
Sulforaphane 1
proline 1
Statin 1
Matrine 1
NTA 1
Hearts 1
phenylacetonitrile 1
Naringin 1
NMDA 1
Naringin 1
acetamide 1
2-oxoglutarate 1
DCP 1
DCB 1
CAN 1
12-hydroxyeicosatetraenoic acid 1
acetamide 1
Celastrol 1
H2S 1
celastrol 1
Desipramine 1
Guo 1
isoleucine 1
Phenethyl isothiocyanate 1
stearic acid 1
MPP 1
caffeine 1
Ochratoxin A 1
Cbl 1
isoleucine 1
stearic acid 1
Ferulic acid 1
benzamide 1
ASA 1
Camptothecin 1
MPP 1
tryptophan 1
PAC 1
Deoxynivalenol 1
AMPA 1
Capsaicin 1
[6]-Shogaol 1
PHT 1
CaO 1
2-phenylnaphthalene 1
Oleandomycin 1
DOPAC 1
hydroxycinnamic acid 1
Pravastatin 1
Lithium chloride 1
Arsenic 1
Nordihydroguaiaretic acid 1
SDS 1
Levetiracetam 1
Camptothecin 1
Matrine 1
DAP 1
Lac 1
Geldanamycin 1
Propionate 1
TTC 1
formic acid 1
p-Coumaric acid 1
vitamin D 1
25-dihydroxycholecalciferol 1
MIA 1
Brazilin 1
Triton 1
DCP 1
carbonate 1
Angiotensin II 1
MDR 1
Valproic acid 1
CMP 1
FK506 1
Epigallocatechin 1
Bisphenol A 1
Se-methylselenocysteine 1
thiophene 1
Nitrite 1
DAP 1
SCC 1
DBM 1
LPR 1
4-chlorophenyl 1
FAD 1
MMD 1
Warfarin 1
formic acid 1
10-Hydroxycamptothecin 1
hexadecyl 1
Tyrosine 1
Gly 1
Cycloheximide 1
Lithium 1
butyric acid 1
Malachite Green 1
Ursolic acid 1
DCB 1
uridine 1
Aloe-emodin 1
formic acid 1
formic acid 1
creatinine 1
3-cyanopyridine 1
Chloroquine 1
Lovastatin 1
Edaravone 1
tryptophan 1
TFT 1
mercury 1
Guo 1
Epigallocatechin gallate 1
BLM 1
Ferulic acid 1
NOXA 1
CoA 1
Vimentin 1
Ketoconazole 1
GTP 1
N-(4-hydroxyphenyl)retinamide 1
hexane 1
Taurine 1
DCB 1
DCB 1
DBP 1
Ethidium bromide 1
more...