Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.B10 (
caspase-7
)
896
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase-3
538
caspase-9
229
PARP
159
Bcl-2
148
caspase-8
143
cytochrome c
109
p53
94
Mol
88
poly(ADP-ribose) polymerase
63
Sep
59
endoplasmic reticulum
57
p21
48
Fas
44
Bid
40
annexin V
37
caspase 7
36
p38
34
inhibitor of apoptosis
32
XIAP
30
JNK
27
more...
Disease
cancer
256
tumor
149
MCF
119
breast cancer
105
carcinoma
33
tumor growth
30
colon cancer
27
leukemia
24
hepatocellular carcinoma
23
carcinogenesis
22
prostate cancer
20
B-cell lymphoma
19
lung cancer
18
glioma
17
adenocarcinoma
17
colorectal cancer
17
tumorigenesis
15
squamous cell carcinoma
12
ischemia
12
Alzheimer's disease
12
more...
Symptom
starvation
3
seizures
2
functional recovery
2
hypothermia
1
hypercapnia
1
hyperoxia
1
pain
1
headache
1
neuralgia
1
erythema
1
Drug
ROS
14
lysine
8
MAP
6
Arsenic trioxide
4
IFN-gamma
4
Taxol
3
IL-2
3
Sorafenib
3
IFN-beta
2
AMC
2
Dermatol
2
ICI
2
ZnO
2
NVP
2
TFT
1
Monensin
1
FAD
1
Estrogens
1
CTX
1
PFT
1
more...
Enzyme
caspase-7
896
caspase-7
896
caspase-3
532
caspase-9
225
PARP
172
caspase-8
138
mitogen-activated protein kinase
75
caspase-6
68
caspase-6
68
caspase-1
46
caspase-2
38
caspase-2
38
ERK
34
protein kinase
18
proteasome
14
MEK
14
protein kinase C
12
cdc2
12
caspase-4
11
granzyme B
11
more...
Compound
DNA
152
Dec
74
oxygen
69
cysteine
41
Asp
38
MDA
34
MTT
33
ADP-ribose
26
TNF
23
glucose
23
calcium
20
ADP
18
iodine
17
dUTP
16
ADP
16
ADP
16
ATP
16
tyrosine
15
alanine
14
sodium
13
more...