Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.62 (caspase-9)
 7,507 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
Death associated protein 3 12.1
EIF3EIP protein 12.1
rheumatoid arthritis-related antigen RA-A47 12.1
CASP-9 12.0
caspase-9 11.7
VEGFC protein 11.3
EMP1 protein 11.3
Apoptotic peptidase activating factor 1 11.1
bridging integrator 2 11.1
ENC-1AS 11.1
PTMA protein 11.1
tropomyosin 3 isoform 2 11.1
Apaf-1 10.7
p21, Cip1 10.5
RNA binding motif, single stranded interacting protein 3 10.5
RAB34 10.5
Tumor suppressor candidate 4 10.5
cysteine-rich protein 3 10.5
OPSG 10.5
Apop-1 10.5
BRCC2 10.5
FPTB 10.5
ZNF23 10.1
Protocadherin-10 10.1
uveal autoantigen with coiled-coil domains and ankyrin repeats 10.1
caspase-8 9.9
apolipoprotein L6 9.7
ra-a47 9.7
claudin 12 9.7
rosbin 9.7
breast carcinoma amplified sequence 1 9.7
claudin-12 9.7
Bid 9.7
RAIDD 9.6
Smac 9.6
APO B-100 9.5
apoptotic peptidase activating factor 1 9.5
G protein-coupled receptor 124 9.5
TNF receptor-associated factor 4 9.5
ZBTB3 9.5
APAF1 protein 9.5
APBB1IP 9.2
3PAP 9.2
small G protein signaling modulator 3 9.2
P63 protein 9.2
longevity assurance gene 1 9.2
LASS5 9.2
endonuclease G 9.2
Bcl-2-like protein 9.2
DFF35 9.1
DIABLO 9.1
MAX dimerization protein 1 9.1
myc proto-oncogene protein 9.1
WW domain-containing protein 2 9.1
CIBZ 9.1
HECTD3 9.1
DAPK1 protein 9.1
NAIP protein 9.1
FEM1B 9.0
CARD-containing protein 9.0
AIF 8.9
poly (ADP-ribose) polymerase 8.9
ubi-d4 8.9
DDX47 8.9
CDKN1A-interacting zinc finger protein 1 8.9
L-type amino acid transporter 2 8.9
APAF-1 8.8
caspase-3 8.8
ICAD 8.8
apoptosis-inducing factor 8.7
claudin 15 8.7
RBM17 8.7
CYP24A1 protein 8.7
PHAPI 8.7
cytochrome c, somatic 8.7
FAAH1 8.7
p53-induced protein 8.7
BLID 8.7
XIAP 8.7
p12 subunit 8.7
more...
Disease
IBD7 11.1
recurrent gallbladder cancer 9.5
Radiocontrast nephropathy 9.2
MDD2 8.6
lung sarcoma 8.4
Mink enteritis 8.2
Neonatal anoxia 8.2
Reovirus infection 8.1
methionine synthase deficiency 8.1
Glycogen storage disease type Ib 8.0
Critical illness myopathy 7.7
Progression of prostate cancer 7.7
cerebral ischemia/hypoxia 7.6
Bacterial endophthalmitis 7.5
Diabetic encephalopathy 7.4
Neonatal necrotizing enterocolitis 7.3
neck neoplasm 7.2
IBD5 7.0
amok 7.0
NINA 6.8
Gastric Carcinoma 6.6
Takahara 6.6
Subependymal giant cell astrocytoma 6.6
Viral myocarditis 6.5
benign ovarian cyst 6.4
Dengue Shock Syndrome 6.4
VES 6.3
STGD1 6.3
salivary gland adenocarcinoma 6.2
Testicular Cancer 6.2
colon neoplasm 6.2
androgen independent prostate cancer 6.2
Hypoxic-ischemic brain injury 6.1
Epithelioma 6.0
AGS 6.0
recurrent colon cancer 6.0
viral arthritis 6.0
ARP1 5.9
Mevalonate kinase deficiency 5.8
ARTS 5.7
Metastatic colorectal cancer 5.6
White Spot 5.6
Transient cerebral ischemia 5.6
Epidermolysis bullosa simplex 5.6
MCF 5.6
adult brain tumor 5.5
Oxygen toxicity 5.5
B-cell lymphoma 5.5
Acute fatty liver of pregnancy 5.4
carbuncle 5.4
HEP 5.4
Chronic mountain sickness 5.4
in situ breast cancer 5.4
alcoholic myopathy 5.4
Sever 5.4
cerebrovascular occlusion 5.3
MTS 5.3
Burkitt-like lymphoma 5.3
hypermethioninemia 5.2
Primary effusion lymphoma 5.2
Oral infection 5.1
HOS 5.1
GA I 5.1
adrenal cancer 5.1
Autosomal recessive polycystic kidney disease 5.1
SME 5.0
DDP 5.0
Osteosarcoma 4.9
Osteosarcoma 4.9
oral cancer 4.9
metastatic cervical cancer 4.9
Photosensitization 4.9
megakaryocytic leukemia 4.9
cancer regression 4.9
FAS 4.9
Cholangiocarcinoma 4.8
acute promyelocytic leukemia 4.8
Ileum 4.8
RP3 4.8
mouse leukemia L1210 4.8
more...
Symptom
not coping 6.8
Motor dysfunction 5.7
infant diarrhea 5.3
male subfertility 4.0
collapse 3.9
halitosis 3.8
hyperemesis 3.8
Tenderness 3.5
loss of balance 3.2
neurological disability 3.2
skin damage 3.1
Catch 3.0
Anoxia 2.9
bradykinesia 2.4
starvation 2.4
hyperoxia 2.3
memory loss 2.2
functional recovery 2.0
nasal discharge 1.6
Neuropathic pain 1.6
despair 1.4
menopausal symptoms 1.4
incoordination 1.3
dry eye 0.7
sore throat 0.6
cachexia 0.6
HSA 0.5
respiratory distress 0.4
hypothermia 0.3
seizures -0.2
diarrhea -0.2
acidity -0.3
thinning -0.4
tinnitus -0.6
cough -0.9
tremor -1.1
nausea and vomiting -1.2
dizziness -1.2
low back pain -1.2
abdominal pain -1.3
angina -1.3
vomiting -1.3
anesthesia -1.4
nausea -1.5
back pain -1.5
weakness -1.6
erythema -1.6
exhaustion -1.7
dyspnea -1.7
analgesia -1.7
headache -2.1
pain -2.4
fatigue -3.6
Drug
Lexatumumab 10.5
Diammonium glycyrrhizinate 9.2
Alexidine 9.1
Mapatumumab 8.7
Proflavin 8.7
Bear bile 8.6
Cupric sulfate 8.1
Gardenia fruit 7.9
Atractylodes rhizome 7.9
Scutellaria root 7.7
Purvalanol 7.5
Epothilone B 7.5
Avasimibe 7.5
Motexafin gadolinium 7.4
Crotonaldehyde 7.4
Irofulven 7.1
Pralatrexate 7.1
Cinnamon oil 7.0
Emodin 7.0
Flavopiridol 6.9
Onconase 6.9
Red ginseng 6.8
Emodin 6.7
3-Methyladenine 6.7
Swainsonine 6.7
Bromelain 6.6
Peridinin 6.6
CED 6.6
Sivelestat 6.5
Eprinomectin 6.4
Sodium ascorbate 6.3
2-Methoxyestradiol 6.3
Azelnidipine 6.2
CA-074 6.2
ROS 6.1
Rauwolfia serpentina 6.0
Hyperforin 6.0
Arsenic trioxide 6.0
PFT 5.9
Revlimid 5.9
Tipifarnib 5.9
Epigallocatechin 5.8
Compound 19 5.6
Cantor 5.5
Mizoribine 5.5
Etoposide 5.4
Nexavar 5.3
Neocarzinostatin 5.3
Compound 15 5.1
Bortezomib 5.1
ADR 5.0
Propidium 5.0
Glycyrrhiza 4.9
Rhamnose 4.9
RBT 4.9
Trabectedin 4.9
Florfenicol 4.9
AMC 4.8
Silica gel 4.8
Acitretin 4.8
Nimesulide 4.8
Fipronil 4.8
Lead acetate 4.7
Monosodium glutamate 4.7
NVP 4.7
Iodixanol 4.7
Artesunate 4.6
SNL 4.5
Agomelatine 4.5
TRM 4.5
Gefitinib 4.4
Parkin 4.4
Ethane 4.4
Parkin 4.4
Propofol 4.3
Vinorelbine 4.3
Taxol 4.3
Verteporfin 4.3
Sorafenib 4.3
Poloxamer 188 4.3
more...
Enzyme
caspase-9 12.1
caspase-8 10.3
caspase-7 10.1
caspase-7 10.0
caspase-10 9.9
caspase-10 9.9
caspase-2 9.8
caspase-2 9.8
caspase-6 9.7
caspase-6 9.7
caspase-3 9.1
caspase-4 9.1
caspase-4 8.9
Omi/HtrA2 8.5
PARP 8.2
Tpa 7.7
caspase-5 7.5
caspase-5 7.4
AO1 6.9
caspase-11 6.6
caspase-11 6.6
electron transfer flavoprotein dehydrogenase 6.3
mu-calpain 6.2
TdT 6.2
DIPP 6.1
palmitoyl-protein thioesterase 6.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.0
aspartase 5.9
m-calpain 5.8
caspase-1 5.7
MPP 5.6
CYP8B1 5.5
cdc2 5.5
neutral sphingomyelinase 5.5
GSK 5.3
inositol 3-kinase 5.2
MMP 5.2
sphingomyelin synthase 5.2
sphingosine kinase 5.1
factor C 5.1
myo-inositol-1-phosphate synthase 5.0
ECH 5.0
stromelysin-3 5.0
mitogen-activated protein kinase 5.0
proline oxidase 5.0
HCS 5.0
deoxyguanosine kinase 4.9
cysteine synthase 4.8
N-acetylglucosaminyltransferase V 4.7
methioninase 4.7
phosphatidylinositol 3-kinase 4.7
ceramidase 4.7
proteinase-3 4.6
farnesyltransferase 4.6
lysine acetyltransferase 4.6
superoxide dismutase 4.6
GD3 synthase 4.5
phosphoinositide 3-kinase 4.5
cathepsin B 4.5
prostacyclin synthase 4.5
SNO 4.5
glutathione peroxidase 4.4
GLO 4.4
PDK1 4.4
MEK 4.3
GM3 synthase 4.3
glutaryl-CoA dehydrogenase 4.3
PRT 4.2
phosphatidylethanolamine N-methyltransferase 4.2
2A protease 4.2
MEKK1 4.2
lactate dehydrogenase 4.2
catalase 4.1
glucosylceramide synthase 4.1
sulfhydryl oxidase 4.1
farnesyltransferase 4.1
bromelain 4.0
granzyme B 3.9
cathepsin D 3.9
AST 3.9
more...
Compound
estra-1,3,5(10)-trien-17-ol 12.1
Withaperuvin B 11.1
Wighteone 11.1
Abyssinone V 11.1
C14H21N3O2 10.5
Cephalostatin 1 10.5
C14H21N3O2 10.5
Spectinabilin 10.5
C14H21N3O2 10.5
C14H21N3O2 10.5
C14H21N3O2 10.5
C14H21N3O2 10.1
Dihydrosanguinarine 10.1
Cajanol 10.1
Murrayanine 10.1
Raddeanin A 9.8
Cirsilineol 9.7
Theasinensin A 9.7
C14H21N3O2 9.7
Nomilin 9.7
1,8-dihydroxy-9(10H)-anthracenone 9.7
Bufotalin 9.7
C14H21N3O2 9.7
Decylubiquinone 9.7
Tigogenin 9.7
C14H21N3O2 9.5
2,5-Dihydroxyacetophenone 9.5
Tambulin 9.5
6,7-dichloro-5,8-quinolinedione 9.2
Deltonin 9.2
methyl 2-benzoylbenzoate 9.2
Bongkrekic acid 9.1
Chimaphilin 9.1
C14H21N3O2 9.1
Codeinone 9.1
Sinularin 9.1
Solamargine 8.9
3-bromo-4,5-dihydroxybenzaldehyde 8.9
PHPS 8.9
Sinulariolide 8.9
Dihydrochalcone 8.7
Tectochrysin 8.7
Tubeimoside I 8.7
5,11-dimethyl-6H-pyrido[4,3-b]carbazole 8.7
2,4-dimethylpyridine 8.7
Poncirin 8.7
Aspidin 8.7
Oridonin 8.6
Monotropein 8.6
Trichothecin 8.6
1,2,5,6-tetrabromocyclooctane 8.6
Berbamine 8.6
Daphnoretin 8.5
3,4-dimethylpyridine 8.5
Aplysin 8.5
Sarcophine 8.5
Visnagin 8.4
Rocaglamide 8.4
BSSG 8.4
Ethyl gallate 8.4
Bullatacin 8.4
Tricetin 8.4
Aloperine 8.4
Ginkgetin 8.3
LLY 8.2
Piperlonguminine 8.2
Obacunone 8.2
Sangivamycin 8.1
Harmol 8.1
Ovatodiolide 8.1
Kaempferide 8.1
Pyronine G 8.1
Lariciresinol 8.1
Neohesperidin 8.1
Phytosphingosine 8.1
5-Hydroxyindole 8.0
lauramide 8.0
Aromadendrin 7.9
Hederagenin 7.9
Dioscin 7.8
more...