Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.62 (caspase-9)
 7,507 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
EIF3EIP protein 12.1
Death associated protein 3 12.1
rheumatoid arthritis-related antigen RA-A47 12.1
CASP-9 12.0
caspase-9 11.7
VEGFC protein 11.3
EMP1 protein 11.3
bridging integrator 2 11.1
tropomyosin 3 isoform 2 11.1
ENC-1AS 11.1
Apoptotic peptidase activating factor 1 11.1
PTMA protein 11.1
Apaf-1 10.7
FPTB 10.5
Tumor suppressor candidate 4 10.5
OPSG 10.5
BRCC2 10.5
Apop-1 10.5
p21, Cip1 10.5
RNA binding motif, single stranded interacting protein 3 10.5
RAB34 10.5
cysteine-rich protein 3 10.5
Protocadherin-10 10.1
uveal autoantigen with coiled-coil domains and ankyrin repeats 10.1
ZNF23 10.1
caspase-8 9.9
breast carcinoma amplified sequence 1 9.7
apolipoprotein L6 9.7
rosbin 9.7
claudin 12 9.7
ra-a47 9.7
claudin-12 9.7
Bid 9.7
RAIDD 9.6
Smac 9.6
APAF1 protein 9.5
ZBTB3 9.5
TNF receptor-associated factor 4 9.5
G protein-coupled receptor 124 9.5
apoptotic peptidase activating factor 1 9.5
more...
Disease
IBD7 11.1
recurrent gallbladder cancer 9.5
Radiocontrast nephropathy 9.2
MDD2 8.6
lung sarcoma 8.4
Neonatal anoxia 8.2
Mink enteritis 8.2
Reovirus infection 8.1
methionine synthase deficiency 8.1
Glycogen storage disease type Ib 8.0
Progression of prostate cancer 7.7
Critical illness myopathy 7.7
cerebral ischemia/hypoxia 7.6
Bacterial endophthalmitis 7.5
Diabetic encephalopathy 7.4
Neonatal necrotizing enterocolitis 7.3
neck neoplasm 7.2
IBD5 7.0
amok 7.0
NINA 6.8
Gastric Carcinoma 6.6
Takahara 6.6
Subependymal giant cell astrocytoma 6.6
Viral myocarditis 6.5
benign ovarian cyst 6.4
Dengue Shock Syndrome 6.4
VES 6.3
STGD1 6.3
salivary gland adenocarcinoma 6.2
Testicular Cancer 6.2
colon neoplasm 6.2
androgen independent prostate cancer 6.2
Hypoxic-ischemic brain injury 6.1
Epithelioma 6.0
viral arthritis 6.0
AGS 6.0
recurrent colon cancer 6.0
ARP1 5.9
Mevalonate kinase deficiency 5.8
ARTS 5.7
more...
Symptom
not coping 6.8
Motor dysfunction 5.7
infant diarrhea 5.3
male subfertility 4.0
collapse 3.9
halitosis 3.8
hyperemesis 3.8
Tenderness 3.5
loss of balance 3.2
neurological disability 3.2
skin damage 3.1
Catch 3.0
Anoxia 2.9
bradykinesia 2.4
starvation 2.4
hyperoxia 2.3
memory loss 2.2
functional recovery 2.0
nasal discharge 1.6
Neuropathic pain 1.6
despair 1.4
menopausal symptoms 1.4
incoordination 1.3
dry eye 0.7
sore throat 0.6
cachexia 0.6
HSA 0.5
respiratory distress 0.4
hypothermia 0.3
seizures -0.2
diarrhea -0.2
acidity -0.3
thinning -0.4
tinnitus -0.6
cough -0.9
tremor -1.1
nausea and vomiting -1.2
dizziness -1.2
low back pain -1.2
abdominal pain -1.3
more...
Drug
Lexatumumab 10.5
Diammonium glycyrrhizinate 9.2
Alexidine 9.1
Mapatumumab 8.7
Proflavin 8.7
Bear bile 8.6
Cupric sulfate 8.1
Gardenia fruit 7.9
Atractylodes rhizome 7.9
Scutellaria root 7.7
Purvalanol 7.5
Epothilone B 7.5
Avasimibe 7.5
Motexafin gadolinium 7.4
Crotonaldehyde 7.4
Irofulven 7.1
Pralatrexate 7.1
Cinnamon oil 7.0
Emodin 7.0
Flavopiridol 6.9
Onconase 6.9
Red ginseng 6.8
Emodin 6.7
3-Methyladenine 6.7
Swainsonine 6.7
Bromelain 6.6
Peridinin 6.6
CED 6.6
Sivelestat 6.5
Eprinomectin 6.4
Sodium ascorbate 6.3
2-Methoxyestradiol 6.3
Azelnidipine 6.2
CA-074 6.2
ROS 6.1
Rauwolfia serpentina 6.0
Hyperforin 6.0
Arsenic trioxide 6.0
PFT 5.9
Revlimid 5.9
more...
Enzyme
caspase-9 12.1
caspase-8 10.3
caspase-7 10.1
caspase-7 10.0
caspase-10 9.9
caspase-10 9.9
caspase-2 9.8
caspase-2 9.8
caspase-6 9.7
caspase-6 9.7
caspase-3 9.1
caspase-4 9.1
caspase-4 8.9
Omi/HtrA2 8.5
PARP 8.2
Tpa 7.7
caspase-5 7.5
caspase-5 7.4
AO1 6.9
caspase-11 6.6
caspase-11 6.6
electron transfer flavoprotein dehydrogenase 6.3
mu-calpain 6.2
TdT 6.2
DIPP 6.1
palmitoyl-protein thioesterase 6.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.0
aspartase 5.9
m-calpain 5.8
caspase-1 5.7
MPP 5.6
CYP8B1 5.5
cdc2 5.5
neutral sphingomyelinase 5.5
GSK 5.3
inositol 3-kinase 5.2
MMP 5.2
sphingomyelin synthase 5.2
sphingosine kinase 5.1
factor C 5.1
more...
Compound
estra-1,3,5(10)-trien-17-ol 12.1
Wighteone 11.1
Abyssinone V 11.1
Withaperuvin B 11.1
C14H21N3O2 10.5
Cephalostatin 1 10.5
Spectinabilin 10.5
C14H21N3O2 10.5
C14H21N3O2 10.5
C14H21N3O2 10.5
C14H21N3O2 10.5
C14H21N3O2 10.1
Cajanol 10.1
Murrayanine 10.1
Dihydrosanguinarine 10.1
Raddeanin A 9.8
Nomilin 9.7
Decylubiquinone 9.7
Theasinensin A 9.7
Bufotalin 9.7
C14H21N3O2 9.7
1,8-dihydroxy-9(10H)-anthracenone 9.7
C14H21N3O2 9.7
Cirsilineol 9.7
Tigogenin 9.7
Tambulin 9.5
2,5-Dihydroxyacetophenone 9.5
C14H21N3O2 9.5
Deltonin 9.2
methyl 2-benzoylbenzoate 9.2
6,7-dichloro-5,8-quinolinedione 9.2
Bongkrekic acid 9.1
Sinularin 9.1
Chimaphilin 9.1
C14H21N3O2 9.1
Codeinone 9.1
PHPS 8.9
Solamargine 8.9
Sinulariolide 8.9
3-bromo-4,5-dihydroxybenzaldehyde 8.9
more...