Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.62 (caspase-9)
 7,507 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-9 7493
caspase-3 4758
Bcl-2 2524
cytochrome c 2176
caspase-8 2021
p53 955
PARP 889
Mol 657
Sep 541
Fas 524
Bid 436
Apaf-1 414
annexin V 403
cytochrome 391
p21 335
ROS 319
p38 317
poly(ADP-ribose) polymerase 308
JNK 286
tumor necrosis factor 262
endoplasmic reticulum 255
superoxide dismutase 246
TNF 245
GSH 220
Bak 219
poly (ADP-ribose) polymerase 218
ATP 217
PI3K 212
XIAP 211
ERK 210
AKT 199
catalase 193
Smac 187
MAPK 179
cyclin D1 172
bcl-2 169
Mcl-1 167
survivin 151
ERK1 151
FasL 148
more...
Disease
cancer 2062
tumor 1204
breast cancer 387
leukemia 342
MCF 315
hepatocellular carcinoma 291
tumor growth 283
carcinoma 271
GSH 220
lung cancer 207
colon cancer 190
B-cell lymphoma 177
prostate cancer 175
melanoma 172
ischemia 161
neuroblastoma 139
adenocarcinoma 129
colorectal cancer 118
gastric cancer 115
carcinogenesis 108
lymphoma 104
non-small cell lung cancer 104
tumorigenesis 94
Alzheimer's disease 93
squamous cell carcinoma 91
glioma 91
Parkinson's disease 90
multiple myeloma 87
cervical cancer 86
ovarian cancer 86
osteosarcoma 84
diabetes 77
liver cancer 74
glioblastoma 67
acute myeloid leukemia 62
liver cancer 57
pancreatic cancer 57
cerebral ischemia 54
acute promyelocytic leukemia 53
chronic myeloid leukemia 47
more...
Symptom
collapse 98
starvation 30
seizures 17
functional recovery 13
pain 12
diarrhea 12
anesthesia 10
hyperoxia 6
respiratory distress 6
hypothermia 5
memory loss 4
acidity 3
cough 3
abdominal pain 3
skin damage 3
headache 3
vomiting 3
weakness 3
bradykinesia 3
tremor 2
neurological disability 2
thinning 2
angina 2
cachexia 2
analgesia 2
halitosis 2
dyspnea 2
nausea 2
loss of balance 1
male subfertility 1
back pain 1
menopausal symptoms 1
Motor dysfunction 1
sore throat 1
erythema 1
infant diarrhea 1
low back pain 1
incoordination 1
Anoxia 1
not coping 1
more...
Drug
ROS 319
vitamin E 34
Monit 33
ascorbate 29
Arsenic trioxide 19
Cardiovasc 17
ADR 16
Taxol 15
MAP 15
Emodin 14
IL-2 14
Emodin 14
Dermatol 14
lysine 13
CED 13
IFN-gamma 13
Bortezomib 12
CTX 12
caffeine 12
Etoposide 11
Ethanol 10
CTX 10
Glycyrrhiza 10
CTX 10
Propofol 10
CSF 9
-deoxyadenosine 9
Parkin 9
NADH 9
MRC 9
p75 9
Parkin 9
AMC 8
Vitamin E 8
Gel 8
Glutathione 8
Sorafenib 7
Indomethacin 7
PFT 7
Ginseng 7
more...
Enzyme
caspase-9 7507
caspase-3 4691
caspase-8 1965
PARP 966
mitogen-activated protein kinase 721
superoxide dismutase 325
ERK 275
catalase 232
caspase-7 228
caspase-7 225
protein kinase 211
caspase-2 166
caspase-2 165
lactate dehydrogenase 125
glutathione peroxidase 109
caspase-6 97
caspase-6 96
proteasome 89
cdc2 88
MEK 85
luciferase 80
caspase-1 76
focal adhesion kinase 75
protein kinase C 75
phosphatidylinositol 3-kinase 66
alanine aminotransferase 66
GSK 63
aspartate aminotransferase 58
caspase-4 46
caspase-4 46
caspase-10 43
AMP-activated protein kinase 43
caspase-10 41
ATPase 37
MMP 36
peroxidase 36
TdT 33
P-glycoprotein 31
phosphoinositide 3-kinase 31
glutathione S-transferase 29
more...
Compound
DNA 1451
oxygen 1233
Dec 568
MTT 567
cysteine 246
TNF 245
GSH 227
GSH 227
ATP 217
MDA 210
calcium 210
iodine 208
dUTP 185
N-acetylcysteine 169
ADP-ribose 160
glucose 157
bromide 152
hydrogen 151
water 148
Asp 138
nitric oxide 128
Cyt 97
Clin 96
sodium 96
alanine 95
ADP 94
H2O2 85
serine 81
ADP 77
ADP 77
Cytochrome c 73
boron 73
ethanol 73
dATP 68
threonine 61
DDP 57
tyrosine 56
acridine 54
Hoechst 33342 53
zinc 52
more...