Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.62 (caspase-9)
 7,507 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-9 7493
caspase-3 4758
Bcl-2 2524
cytochrome c 2176
caspase-8 2021
p53 955
PARP 889
Mol 657
Sep 541
Fas 524
Bid 436
Apaf-1 414
annexin V 403
cytochrome 391
p21 335
ROS 319
p38 317
poly(ADP-ribose) polymerase 308
JNK 286
tumor necrosis factor 262
more...
Disease
cancer 2062
tumor 1204
breast cancer 387
leukemia 342
MCF 315
hepatocellular carcinoma 291
tumor growth 283
carcinoma 271
GSH 220
lung cancer 207
colon cancer 190
B-cell lymphoma 177
prostate cancer 175
melanoma 172
ischemia 161
neuroblastoma 139
adenocarcinoma 129
colorectal cancer 118
gastric cancer 115
carcinogenesis 108
more...
Symptom
collapse 98
starvation 30
seizures 17
functional recovery 13
pain 12
diarrhea 12
anesthesia 10
respiratory distress 6
hyperoxia 6
hypothermia 5
memory loss 4
bradykinesia 3
acidity 3
weakness 3
cough 3
vomiting 3
skin damage 3
headache 3
abdominal pain 3
tremor 2
more...
Drug
ROS 319
vitamin E 34
Monit 33
ascorbate 29
Arsenic trioxide 19
Cardiovasc 17
ADR 16
Taxol 15
MAP 15
Emodin 14
Dermatol 14
IL-2 14
Emodin 14
lysine 13
IFN-gamma 13
CED 13
CTX 12
caffeine 12
Bortezomib 12
Etoposide 11
more...
Enzyme
caspase-9 7507
caspase-3 4691
caspase-8 1965
PARP 966
mitogen-activated protein kinase 721
superoxide dismutase 325
ERK 275
catalase 232
caspase-7 228
caspase-7 225
protein kinase 211
caspase-2 166
caspase-2 165
lactate dehydrogenase 125
glutathione peroxidase 109
caspase-6 97
caspase-6 96
proteasome 89
cdc2 88
MEK 85
more...
Compound
DNA 1451
oxygen 1233
Dec 568
MTT 567
cysteine 246
TNF 245
GSH 227
GSH 227
ATP 217
MDA 210
calcium 210
iodine 208
dUTP 185
N-acetylcysteine 169
ADP-ribose 160
glucose 157
bromide 152
hydrogen 151
water 148
Asp 138
more...