Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.61 (caspase-8)
6,833 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-8 0.749
caspase-9 0.061
Bid 0.039
caspase-3 0.031
FADD 0.031
FLICE 0.025
Fas 0.023
c-FLIP 0.014
FLIP 0.010
Bcl-2 0.009
cytochrome c 0.009
TRAIL 0.007
CD95 0.006
FasL 0.005
Fas-associated death domain protein 0.005
PARP 0.004
DR5 0.004
Fas ligand 0.004
RIPK1 0.003
TNF-related apoptosis-inducing ligand 0.003
Smac 0.003
RIPK3 0.002
TRAIL-R2 0.002
death receptor 5 0.002
XIAP 0.002
TRAIL-R1 0.002
poly(ADP-ribose) polymerase 0.002
RIP1 0.002
Bak 0.002
CD95L 0.002
Apaf-1 0.002
MLKL 0.001
annexin V 0.001
poly (ADP-ribose) polymerase 0.001
DR4 0.001
DIABLO 0.001
TRADD 0.001
BID 0.001
cIAP1 0.001
tumor necrosis factor 0.001
inhibitor of apoptosis 0.001
APO-1 0.001
RIP3 0.001
cIAP2 0.001
AIF 0.001
p53 0.001
TNFR1 0.001
Tumor necrosis factor 0.001
TNF receptor 0.001
Bcl-X 0.001
apoptosis-inducing factor 0.001
Mcl-1 0.001
DcR2 0.001
X-linked inhibitor of apoptosis protein 0.001
JNK 0.001
endonuclease G 0.001
ICAD 0.001
DcR1 0.000
caspase 10 0.000
TNF 0.000
Bax protein 0.000
p38 0.000
anti-apoptotic protein 0.000
IAP 0.000
caspase 2 0.000
TNF-R1 0.000
pro-apoptotic protein 0.000
survivin 0.000
TRAF2 0.000
FAS 0.000
TNFR1-associated death domain protein 0.000
FLICE-associated huge protein 0.000
BH3 interacting domain death agonist 0.000
DEDD2 0.000
tumor necrosis factor receptor 0.000
claudin-12 0.000
RIP 0.000
p21 0.000
FADD protein 0.000
RAIDD 0.000
more...
Disease
cancer 0.000
tumor 0.000
FAS 0.000
MCF 0.000
leukemia 0.000
autoimmune lymphoproliferative syndrome 0.000
colon cancer 0.000
LACH 0.000
hepatocellular carcinoma 0.000
tumor growth 0.000
HMN7B 0.000
Acute glaucoma 0.000
breast cancer 0.000
neuroblastoma 0.000
B-cell lymphoma 0.000
acute promyelocytic leukemia 0.000
GSH 0.000
prostate cancer 0.000
glioma 0.000
multiple myeloma 0.000
AGS 0.000
Tumour necrosis 0.000
glioblastoma 0.000
carcinoma 0.000
lung cancer 0.000
osteosarcoma 0.000
liver cancer 0.000
DFNB59 0.000
CEM 0.000
melanoma 0.000
methionine synthase deficiency 0.000
adenocarcinoma 0.000
Reovirus infection 0.000
lymphoma 0.000
cervical cancer 0.000
cowpox 0.000
AIDS cholangiopathy 0.000
colorectal cancer 0.000
myeloid leukemia 0.000
liver cancer 0.000
Blocking 0.000
ischemia 0.000
non-small cell lung cancer 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
salivary gland cancer 0.000
CYLD 0.000
ovarian cancer 0.000
acute myeloid leukemia 0.000
KRS 0.000
Glioblastoma 0.000
carcinogenesis 0.000
molluscum contagiosum 0.000
Corneal infection 0.000
gastric cancer 0.000
epithelial ovarian cancer 0.000
tumorigenesis 0.000
squamous cell carcinoma 0.000
amok 0.000
pancreatic cancer 0.000
oral cancer 0.000
AD5 0.000
salivary gland adenoid cystic carcinoma 0.000
MTS 0.000
childhood rhabdomyosarcoma 0.000
skin cancer 0.000
DDP 0.000
mouse leukemia P388 0.000
VED 0.000
tumor progression 0.000
Canine distemper 0.000
lung carcinoma 0.000
Leukemia 0.000
Burkitt's lymphoma 0.000
salivary gland adenocarcinoma 0.000
glioblastoma multiforme 0.000
Testicular Cancer 0.000
colon neoplasm 0.000
Cytokine storm 0.000
Osteosarcoma 0.000
more...
Symptom
collapse 0.000
bradypnea 0.000
hyperemesis 0.000
starvation 0.000
hyperoxia 0.000
Tenderness 0.000
skin damage 0.000
splenomegaly 0.000
loss of balance 0.000
hypothermia 0.000
ataxic gait 0.000
halitosis 0.000
dry eye 0.000
functional recovery 0.000
menopausal symptoms 0.000
memory loss 0.000
hot flashes 0.000
sore throat 0.000
cachexia 0.000
seizures 0.000
alexithymia 0.000
exhaustion 0.000
insomnia 0.000
thinning 0.000
diarrhea 0.000
HSA 0.000
acute stress 0.000
respiratory distress 0.000
flushing 0.000
myalgia 0.000
tinnitus 0.000
tremor 0.000
dystonia 0.000
syncope 0.000
weakness 0.000
nausea and vomiting 0.000
dizziness 0.000
low back pain 0.000
overweight 0.000
back pain 0.000
anesthesia 0.000
sleepiness 0.000
erythema 0.000
abdominal pain 0.000
headache 0.000
acidity 0.000
ataxia 0.000
pain 0.000
discomfort 0.000
nausea 0.000
discomfort 0.000
dyspnea 0.000
Drug
Edratide 0.000
ROS 0.000
Bortezomib 0.000
2-Iminobiotin 0.000
Lexatumumab 0.000
Alexidine 0.000
Flavopiridol 0.000
Zedoary 0.000
Mapatumumab 0.000
3,4-Dichloroisocoumarin 0.000
Bear bile 0.000
Methadone hydrochloride 0.000
2-Methoxyestradiol 0.000
CED 0.000
Radicicol 0.000
Cupric sulfate 0.000
Naftopidil 0.000
Citrus unshiu peel 0.000
Mevastatin 0.000
Sodium ascorbate 0.000
Avasimibe 0.000
p75 0.000
Motexafin gadolinium 0.000
Berberine chloride 0.000
Irofulven 0.000
Hyperforin 0.000
Trabectedin 0.000
Lonafarnib 0.000
Ilomastat 0.000
Bucillamine 0.000
Arsenic trioxide 0.000
Taxol 0.000
Olomoucine 0.000
Peridinin 0.000
CA-074 0.000
IFN-beta 0.000
Nafamostat mesilate 0.000
IL-2 0.000
Dextran sulfate sodium 0.000
ADR 0.000
Glycyrrhiza 0.000
Etoposide 0.000
Epigallocatechin 0.000
Revlimid 0.000
Zebularine 0.000
IFN-gamma 0.000
Swainsonine 0.000
Emodin 0.000
Rasburicase 0.000
Vorinostat 0.000
Emodin 0.000
Batimastat 0.000
Batimastat 0.000
Sorafenib 0.000
Cantor 0.000
Mizoribine 0.000
Thioridazine 0.000
Onconase 0.000
Compound 18 0.000
Propidium 0.000
ID2 0.000
Etodolac 0.000
RBT 0.000
CCL 0.000
vitamin E 0.000
Dasatinib 0.000
Artesunate 0.000
Triad 0.000
NVP 0.000
-deoxyadenosine 0.000
Triad 0.000
Propofol 0.000
Bromelain 0.000
Bosentan 0.000
Bosentan 0.000
AMC 0.000
Rolipram 0.000
Casodex 0.000
Cetrorelix 0.000
BLyS 0.000
more...
Enzyme
caspase-8 1.000
caspase-9 0.075
caspase-3 0.039
caspase-10 0.010
caspase-10 0.010
caspase-2 0.005
caspase-2 0.004
PARP 0.004
caspase-7 0.003
caspase-7 0.003
caspase-6 0.003
caspase-6 0.003
caspase-1 0.001
caspase-4 0.001
caspase-4 0.001
mitogen-activated protein kinase 0.001
caspase-11 0.000
caspase-11 0.000
Omi/HtrA2 0.000
caspase-5 0.000
caspase-5 0.000
proteasome 0.000
ERK 0.000
granzyme B 0.000
TdT 0.000
acylcarnitine hydrolase 0.000
cdc2 0.000
IKK 0.000
protein kinase 0.000
MEK 0.000
catalase 0.000
cathepsin B 0.000
superoxide dismutase 0.000
phosphatidylinositol 3-kinase 0.000
lombricine kinase 0.000
protein kinase C 0.000
lactate dehydrogenase 0.000
focal adhesion kinase 0.000
adamalysin 0.000
AO1 0.000
MMP 0.000
neutral sphingomyelinase 0.000
ECH 0.000
GSK 0.000
luciferase 0.000
phosphoinositide 3-kinase 0.000
m-calpain 0.000
calcineurin 0.000
mu-calpain 0.000
sphingomyelin synthase 0.000
glutathione peroxidase 0.000
cathepsin D 0.000
DIPP 0.000
lysyl-tRNA synthetase 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
p100 0.000
topoisomerase 0.000
P-glycoprotein 0.000
3-hydroxy-3-methylglutaryl-CoA lyase 0.000
topoisomerase 0.000
sphingosine kinase 0.000
protein phosphatase 2A 0.000
ceramidase 0.000
alanine aminotransferase 0.000
RNase 0.000
succinate dehydrogenase 0.000
aspartase 0.000
RNase 0.000
AFR 0.000
aspartate aminotransferase 0.000
glutathione reductase 0.000
AMP-activated protein kinase 0.000
NADPH oxidase 0.000
NADPH oxidase 0.000
complex I 0.000
glutathione S-transferase 0.000
DNA ligase 0.000
DNA ligase 0.000
ribonucleotide reductase 0.000
ribonucleotide reductase 0.000
more...
Compound
TNF 0.000
dUTP 0.000
MTT 0.000
ADP-ribose 0.000
24-Hydroxycholesterol 0.000
DNA 0.000
estra-1,3,5(10)-trien-17-ol 0.000
Justicidin A 0.000
oxygen 0.000
Sarcophine 0.000
MDA 0.000
4-chloro-N-methylbenzamide 0.000
Asp 0.000
cysteine 0.000
Cephalostatin 1 0.000
7-Ketocholesterol 0.000
C14H21N3O2 0.000
C14H21N3O2 0.000
C14H21N3O2 0.000
Glucoraphenin 0.000
C14H21N3O2 0.000
Cephalochromin 0.000
C14H21N3O2 0.000
Raddeanin A 0.000
Cytochrome c 0.000
N-acetylcysteine 0.000
Dihydrosanguinarine 0.000
C14H21N3O2 0.000
C14H21N3O2 0.000
Rocaglamide 0.000
Tigogenin 0.000
2-hexadecanol 0.000
C14H21N3O2 0.000
Saucernetin 0.000
ASC 0.000
alpha-Santalol 0.000
2,5-Dihydroxyacetophenone 0.000
C14H21N3O2 0.000
Gartanin 0.000
Linoelaidic acid 0.000
Lupulone 0.000
Deltonin 0.000
methyl 2-benzoylbenzoate 0.000
Celastrol 0.000
GSH 0.000
GSH 0.000
androst-2-en-17-one 0.000
Codeinone 0.000
Sinularin 0.000
C14H21N3O2 0.000
boron 0.000
Chelidonine 0.000
hydroxymethylphosphonic acid 0.000
Didodecyldimethylammonium bromide 0.000
PHPS 0.000
Hoechst 33342 0.000
Sanguinarine 0.000
Dihydrochalcone 0.000
2,4-dimethylpyridine 0.000
Tectochrysin 0.000
N-hydroxybutanamide 0.000
Bufotalin 0.000
Nomilin 0.000
Cyt 0.000
Ursolic acid 0.000
iodine 0.000
Phenethyl isothiocyanate 0.000
Ginkgetin 0.000
cis-Jasmone 0.000
2-hydroxy-1-propanesulfonic acid 0.000
celastrol 0.000
Decursin 0.000
2-Methoxyestradiol 0.000
Dicentrine 0.000
N-hydroxybutanamide 0.000
3,4-dimethylpyridine 0.000
Curcumin 0.000
Cordycepin 0.000
Cordycepin 0.000
Bullatacin 0.000
more...