Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.22.61 (caspase-8)
6,833 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein caspase-8 6750 caspase-3 3145 caspase-9 1986 Bcl-2 1477 Fas 1456 cytochrome c 1210 Bid 785 tumor necrosis factor 645 p53 631 Mol 602 PARP 571 FADD 528 Sep 487 TNF 421 TRAIL 394 CD95 385 FLICE 373 FasL 333 Fas ligand 325 cytokine 289 annexin V 286 p38 285 c-FLIP 266 DR5 259 FLIP 256 JNK 248 poly(ADP-ribose) polymerase 244 endoplasmic reticulum 202 p21 191 XIAP 181 Bak 178 Tumor necrosis factor 169 DR4 161 MAPK 156 RIPK1 155 TNF-alpha 154 ERK 150 ROS 149 cytochrome 147 Smac 145 more...

Disease cancer 1812 tumor 1077 leukemia 346 breast cancer 298 hepatocellular carcinoma 224 MCF 203 carcinoma 201 tumor growth 201 prostate cancer 152 colon cancer 152 lung cancer 137 GSH 127 melanoma 124 ischemia 122 neuroblastoma 121 adenocarcinoma 117 lymphoma 116 multiple myeloma 103 glioma 100 colorectal cancer 95 carcinogenesis 92 B-cell lymphoma 91 tumorigenesis 80 FAS 78 acute myeloid leukemia 70 glioblastoma 69 squamous cell carcinoma 69 gastric cancer 67 osteosarcoma 65 ovarian cancer 63 cervical cancer 62 Alzheimer's disease 61 liver cancer 61 non-small cell lung cancer 60 acute promyelocytic leukemia 60 diabetes 58 tumor progression 55 pancreatic cancer 46 virus infection 45 liver cancer 43 more...

Symptom collapse 43 starvation 17 seizures 14 hypothermia 11 splenomegaly 9 functional recovery 8 diarrhea 8 hyperoxia 7 pain 6 anesthesia 5 exhaustion 4 headache 3 skin damage 3 thinning 3 dry eye 3 weakness 3 memory loss 3 cachexia 3 insomnia 3 respiratory distress 3 menopausal symptoms 2 tremor 2 sore throat 2 overweight 2 abdominal pain 2 nausea and vomiting 1 nausea 1 ataxia 1 loss of balance 1 hot flashes 1 discomfort 1 acidity 1 HSA 1 dizziness 1 ataxic gait 1 back pain 1 alexithymia 1 erythema 1 low back pain 1 syncope 1 more...

Drug ROS 149 IL-2 41 IFN-gamma 39 Bortezomib 29 Dermatol 25 p75 23 vitamin E 21 lysine 20 ascorbate 17 Taxol 16 Monit 15 IFN-beta 13 Cardiovasc 11 CED 11 Arsenic trioxide 10 CSF 10 ADR 10 MAP 9 caffeine 9 Ethanol 9 Flavopiridol 8 Mutagen 8 Glycyrrhiza 8 MRC 7 Etoposide 7 Sorafenib 7 2-Methoxyestradiol 6 Propofol 6 CTX 6 G-CSF 6 -deoxyadenosine 6 Vitamin E 5 CCL 5 AMC 4 NVP 4 Indomethacin 4 Angiotensin II 4 EE2 4 ICI 4 ALA 4 more...

Enzyme caspase-8 6833 caspase-3 3091 caspase-9 1965 PARP 625 mitogen-activated protein kinase 613 caspase-1 245 ERK 223 protein kinase 164 caspase-2 156 caspase-2 155 caspase-7 142 caspase-7 138 proteasome 123 superoxide dismutase 115 caspase-10 114 catalase 114 caspase-10 110 caspase-6 99 caspase-6 96 protein kinase C 80 focal adhesion kinase 71 MEK 68 lactate dehydrogenase 58 luciferase 58 cdc2 56 caspase-4 48 phosphatidylinositol 3-kinase 48 caspase-4 47 IKK 42 granzyme B 36 glutathione peroxidase 36 calcineurin 35 alanine aminotransferase 34 cathepsin B 30 aspartate aminotransferase 28 caspase-11 28 caspase-11 28 ATPase 27 TdT 27 glutathione S-transferase 26 more...

Compound DNA 1148 oxygen 674 Dec 527 TNF 421 MTT 288 cysteine 249 Asp 177 MDA 157 dUTP 142 GSH 130 GSH 130 calcium 127 iodine 124 alanine 113 ADP-ribose 107 Clin 102 nitric oxide 90 ATP 90 N-acetylcysteine 88 glucose 87 boron 82 bromide 78 serine 77 water 75 threonine 67 sodium 66 hydrogen 59 tyrosine 59 ADP 54 ADP 52 ADP 51 ethanol 49 acetate 47 Ile 43 THP 41 THP 41 MEK 41 Curcumin 41 leucine 39 DDP 38 more...

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