Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.61 (caspase-8)
 6,833 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase and RIP adapter with death domain 12.2
NADH-ubiquinone oxidoreductase B18 subunit 12.2
EFR3 homolog B 12.2
Death associated protein 3 12.2
caspase-8 11.8
G1/S-specific cyclin E2 11.2
Sal-like 4 (Drosophila) 11.2
sorting nexin 7 11.2
C4orf22 11.2
Apoptotic peptidase activating factor 1 11.2
FLICE 11.0
Fas-associated death domain protein 10.9
FADD 10.9
DEDD2 10.9
c-FLIP 10.7
Bid 10.6
EPH receptor B4 10.6
PTPRK protein 10.6
inhibitor of growth family, member 3 10.6
FLICE-associated huge protein 10.6
DOPEY1 10.6
TNFR1-associated death domain protein 10.3
FLIP 10.3
Squamous cell carcinoma antigen 1 10.2
pFIV 10.2
EFR3B 10.2
NUDT10 10.2
receptor (TNFRSF)-interacting serine-threonine kinase 1 10.2
PMEPA1 protein 10.2
BAP29 10.2
uveal autoantigen with coiled-coil domains and ankyrin repeats 10.2
CASP-9 10.0
death effector domain-containing 10.0
FAS-associated death domain protein 9.9
caspase-9 9.9
ING3 protein 9.9
hRFI 9.9
claudin 12 9.9
DFF35 9.9
CARD12 9.9
GAGE-7 9.9
TNFRSF1A-associated via death domain 9.9
apolipoprotein L6 9.9
SH3RF2 9.9
rosbin 9.9
claudin-12 9.8
death receptor 5 9.8
HIPPI 9.7
ICH-2 9.7
caspase 10 9.7
BH3 interacting domain death agonist 9.7
TRAIL-R2 9.7
FADD protein 9.7
RIPK3 9.6
TMEM219 9.6
cds2 9.6
G protein-coupled receptor 124 9.6
RGPR-p117 9.6
SERP2 9.6
fucosyltransferase 3 9.6
TRADD 9.5
CRADD 9.5
TNF-related apoptosis-inducing ligand 9.4
RIPK1 9.4
RAIDD 9.4
longevity assurance gene 1 9.4
LASS5 9.4
CA-XIV 9.4
APBB1IP 9.4
RIP-1 9.3
DcR1 9.3
Smac 9.3
TNF receptor-associated protein 9.3
RIP1 9.3
TRAIL-R1 9.3
p12 subunit 9.2
myc proto-oncogene protein 9.2
PYPAF7 9.2
102kD 9.2
NHLRC2 9.2
HECTD3 9.2
ICEBERG 9.2
Z-DNA binding protein 1 9.1
DAP3 9.1
DcR2 9.1
TRAIL 9.1
cIAP1 9.1
MLKL 9.1
RIP3 9.1
PUS7 9.0
c-myc binding protein 9.0
zinc finger protein 91 9.0
ASB3 9.0
FasL 9.0
Fas 9.0
DR5 9.0
ICAD 9.0
CD95 8.9
CFLAR 8.9
TOSO 8.9
PAPK 8.9
ACVR1C 8.9
CYP24A1 protein 8.9
SNX7 8.9
ribosomal protein L39 8.9
cytochrome c, somatic 8.9
claudin 15 8.9
2-hydroxyphytanoyl-CoA lyase 8.9
FAS ligand 8.9
Apaf-1 8.8
endonuclease G 8.8
CD95L 8.8
RNF183 8.7
GSDMC 8.7
pyrin domain containing 1 8.7
Inhibitory PAS domain protein 8.7
Gal-T2 8.7
DIABLO 8.7
Che-1 8.7
PSTPIP2 8.7
PEA-15 8.7
caspase 2 8.7
RIP-3 8.6
XIAP 8.6
AIF 8.6
DEDD 8.6
gasdermin 8.6
FBXO45 8.6
HOIL-1 8.6
PNAS-4 8.6
ZBP1 8.6
apoptosis-inducing factor) 8.6
TNF-related apoptosis-inducing ligand receptor 2 8.5
death receptor 6 8.5
caspase-14 8.5
FAIM 8.5
claudin-15 8.5
Ret finger protein 8.5
Hyal-3 8.5
Factor associated with neutral sphingomyelinase activation 8.5
monocarboxylate transporter isoform 1 8.5
CAP2 8.5
cIAP2 8.5
Fas ligand 8.5
prostate apoptosis response-4 8.5
APO1 8.4
CARP-1 8.4
RAPGEF2 8.4
PCTAIRE1 8.4
XIAP-associated factor 1 8.4
AIM2 protein 8.4
PRKR-like endoplasmic reticulum kinase 8.4
TRIM13 8.4
casp 8.4
APO-1 8.4
CYCS 8.4
caspase-3 8.3
BID 8.3
X-linked inhibitor of apoptosis protein 8.3
Bak 8.3
DLM-1 8.3
TBP-related factor 2 8.3
PTGES2 8.3
RFC140 8.3
hUPF2 8.3
gasdermin D 8.3
DFNB59 8.3
poly (ADP-ribose) polymerase 8.3
KRS 8.2
NOK 8.2
mixed lineage kinase 8.2
EIF4A1 8.2
protein kinase C iota 8.2
CDIP 8.2
SPON1 8.2
CAP3 8.2
SHARPIN 8.2
TNF receptor-associated factor 2 8.1
PCTK1 8.1
death-associated protein 3 8.1
NFKBIB 8.1
WW domain containing E3 ubiquitin protein ligase 1 8.1
TNFR1 8.1
DENN 8.1
ING3 8.1
DR-4 8.0
Bcl-10 8.0
RDH8 8.0
Insulin receptor substrate-2 8.0
MEPI 8.0
CIDE-B 8.0
CMH-1 8.0
PRG1 8.0
apoptosis-inducing factor 8.0
PARP 8.0
caspase-activated DNase 8.0
TNF-R1 8.0
putative anion transporter 7.9
transforming growth factor-beta-activated kinase 1 7.9
SNTA1 7.9
AB13 7.9
TRAF2 7.9
poly(ADP-ribose) polymerase 7.9
DR4 7.9
inhibitor of apoptosis 7.9
p20 7.9
cytochrome c 7.9
KLRD1 7.9
STAMP2 7.9
CASP8 7.9
TNF-induced protein 7.9
death receptor 3 7.9
HYPK 7.9
Bcl-X 7.8
TNFSF10 7.8
hUpf1 7.8
ZNF259 7.8
ST3GAL3 7.8
rpS3 7.8
ADCYAP1R1 7.8
apoptosis-related protein 7.8
IAP2 7.8
LIT 7.7
DGK-zeta 7.7
FACL4 7.7
Bik 7.7
DRw11 7.7
CPP32 7.7
Bcl-2 7.7
CRTAM 7.7
PTGES3 7.7
differentially expressed in normal and neoplastic cells 7.7
cathepsin W 7.7
NLRP6 7.7
DEFT 7.7
p43 7.6
IAP 7.6
TNFRSF10B 7.6
caspase 4 7.6
DFF40 7.6
EPHB4 7.6
TNFRSF6 7.6
BAK 7.6
KOX 7.6
BCL-G 7.6
FAF1 7.6
SORBS1 7.6
Gap junction protein 7.6
pro-apoptotic Bcl-2 protein 7.6
NP25 7.6
caspase 6 7.6
pro-apoptotic protein 7.6
Bax protein 7.6
vezatin 7.5
IRGC 7.5
PRAP 7.5
Hyal-1 7.5
AKAP1 7.5
brother of the regulator of imprinted sites 7.5
SUSD2 7.5
m3 muscarinic acetylcholine receptor 7.5
CAP1 7.5
E1B19K 7.5
APP-BP1 7.5
BM88 7.5
Glycogen synthase kinase 3 beta 7.5
TP53INP2 7.5
sphingomyelin synthase 1 7.5
methionine adenosyltransferase II 7.5
ANXA1 protein 7.5
H2A histone family member 7.5
ICH3 7.5
TNFSF7 7.4
NOMO 7.4
HYAL-1 7.4
doublecortin-like kinase 7.4
TOM22 7.4
GALNT14 7.4
PYGL 7.4
ABCF1 7.4
RIP 7.4
caspase 7 7.4
Decoy receptor 3 7.4
Sharpin 7.4
IKK1 7.4
Caspase-14 7.4
Calpain-2 7.4
Ras-related GTP-binding protein 7.4
Hyal-2 7.4
RNF31 7.4
RCC4 7.4
Mcl-1 7.4
PIDD 7.3
TMS1 7.3
p18 7.3
XB130 7.3
IL-20R1 7.3
EWS-Fli1 7.3
Bcl-2-like protein 7.3
Daxx 7.3
HSC3 7.3
NLRC4 7.3
TNF receptor 7.3
APAF-1 7.2
PTPL1 7.2
calpain-like protease 7.2
TNFRSF8 7.2
Tissue factor pathway inhibitor-2 7.2
MADD 7.2
LASS2 7.2
Bcl-w 7.2
NFAT4 7.2
FAS 7.2
O48 7.2
TIEG 7.2
fas 7.2
CHIA 7.2
THH 7.2
NRCAM 7.2
adenylate kinase 2 7.2
more...
Disease
LACH 10.6
HMN7B 10.2
Acute glaucoma 9.5
DFNB59 8.3
methionine synthase deficiency 8.2
autoimmune lymphoproliferative syndrome 8.0
AIDS cholangiopathy 7.8
Reovirus infection 7.7
Corneal infection 7.3
amok 7.1
KRS 7.0
AD5 7.0
salivary gland adenoid cystic carcinoma 6.9
salivary gland cancer 6.9
childhood rhabdomyosarcoma 6.6
mouse leukemia P388 6.6
VED 6.5
FAS 6.5
CYLD 6.4
salivary gland adenocarcinoma 6.4
Testicular Cancer 6.3
colon neoplasm 6.3
Cytokine storm 6.3
DFNA5 6.2
Epithelioma 6.1
Chronic beryllium disease 6.1
cowpox 6.0
Canine distemper 5.8
VES 5.8
molluscum contagiosum 5.8
Metastatic colorectal cancer 5.8
Aspergillus fumigatus infection 5.7
Tumour necrosis 5.7
Epidermolysis bullosa simplex 5.7
Mucolipidosis type IV 5.7
AGS 5.6
carbuncle 5.5
X-linked lymphoproliferative syndrome 5.5
retinal vascular occlusion 5.4
pediatric solid tumor 5.3
DRD 5.3
Oral infection 5.3
Neuroblastoma 5.2
Neuroblastoma 5.2
Barth syndrome 5.2
adrenal cancer 5.2
closed angle glaucoma 5.2
acute promyelocytic leukemia 5.2
ED3 5.2
Inverted papilloma 5.1
Askin tumor 5.1
Vesicular stomatitis 5.1
MCF 5.1
Photosensitization 5.1
CEM 5.1
cancer regression 5.0
LGL leukemia 5.0
Ileum 5.0
RP3 5.0
testicular dysfunction 5.0
Retinal ischemia 5.0
cervical adenocarcinoma 4.9
Glioblastoma 4.9
myeloid leukemia 4.9
Aeromonas hydrophila infection 4.9
Candida albicans infection 4.8
CM1 4.8
FGG 4.8
Keshan disease 4.8
mast cell leukemia 4.8
HEP 4.7
Acute liver failure 4.7
MTS 4.7
B-cell lymphoma 4.7
adrenocortical cancer 4.7
HOS 4.6
Mouse hepatitis 4.6
lymphomatoid granulomatosis 4.6
monocytic leukemia 4.6
colon cancer 4.6
Chemoradiation 4.6
anaplastic thyroid cancer 4.5
Osteosarcoma 4.5
Osteosarcoma 4.5
Insulinoma 4.5
herpes labialis 4.5
ileocolitis 4.5
Neonatal sepsis 4.5
Gallbladder carcinoma 4.5
myocardial hypoxia 4.5
ASM 4.5
immunotoxicity 4.4
Kashin-Beck disease 4.4
histiocytic lymphoma 4.4
Malignant glioma 4.4
TNS 4.4
Invasive pulmonary aspergillosis 4.4
Angiostrongylus cantonensis 4.4
bone neoplasm 4.4
vitamin B6 deficiency 4.3
neuroblastoma 4.3
diabetic hyperglycemia 4.3
uterine sarcoma 4.3
Pseudomonas infection 4.3
Colon cancer 4.3
Shigella boydii 4.3
Simpson-Golabi-Behmel syndrome 4.3
Primary effusion lymphoma 4.3
malignant meningioma 4.3
Blocking 4.3
oral cancer 4.3
HCC 4.2
liver cancer 4.2
Bowen's disease 4.2
Medulloblastoma 4.2
CCL 4.2
osteosarcoma 4.2
Autosomal recessive polycystic kidney disease 4.2
bone cancer 4.2
multicentric Castleman's disease 4.2
hemangiosarcoma 4.2
immune disorder 4.1
PARK7 4.1
glioblastoma 4.1
liver cancer 4.1
DDP 4.1
refractory cancer 4.1
leukemia 4.1
Choriocarcinoma 4.1
metastatic neuroblastoma 4.1
malignant mesothelioma 4.1
renal ischemia 4.1
megakaryocytic leukemia 4.0
adult T-cell leukemia/lymphoma 4.0
tumor growth 4.0
RARS 4.0
Wright 4.0
GSH 4.0
toxic nodular goiter 3.9
EGC 3.9
Ureteral obstruction 3.9
beryllium disease 3.9
Burkitt's lymphoma 3.9
BEN 3.9
Vascular lesions 3.9
glioma 3.9
blood cancer 3.9
T-cell acute lymphoblastic leukemia 3.9
hormone refractory prostate cancer 3.9
ARC 3.9
hypertensive retinopathy 3.9
hepatocellular carcinoma 3.9
Rhabdomyosarcoma 3.9
epithelial ovarian cancer 3.9
Immune thrombocytopenia 3.8
metastatic neuroblastoma 3.8
PBD 3.8
OPA1 3.8
pneumonic plague 3.8
leukoderma 3.8
LYP 3.8
medulloblastoma 3.8
HIV encephalitis 3.8
FDC 3.8
West Nile Virus 3.7
glutaric aciduria 3.7
Cerebral malaria 3.7
multiple myeloma 3.7
histiocytic lymphoma 3.7
Nasopharyngeal carcinoma 3.7
cervical cancer 3.7
epididymo-orchitis 3.7
protozoan infection 3.7
Bielschowsky 3.7
NOD 3.6
disc degeneration 3.6
non-small cell lung cancer 3.6
Hepatotoxicity 3.6
solid tumor 3.6
APL 3.6
glioblastoma multiforme 3.6
DMC 3.6
bubonic plague 3.6
Spinocerebellar ataxia 3.6
African horse sickness 3.6
complicated pregnancy 3.6
prostate cancer 3.6
neck cancer 3.6
Adenovirus 3.6
ocular melanoma 3.6
skin cancer 3.6
APL 3.6
Lymphatic filariasis 3.5
aminoaciduria 3.5
Multiple system atrophy 3.5
ileitis 3.5
PML 3.5
BCG infection 3.5
NS2 3.4
acute monocytic leukemia 3.4
Hypertrophic 3.4
Allergic asthma 3.4
ovarian cancer 3.4
pancreatic cancer 3.4
B-cell chronic lymphocytic leukemia 3.4
Hepatocellular carcinoma 3.4
hepatoblastoma 3.3
Parry 3.3
CP1 3.3
Alcoholic liver disease 3.3
epithelioma 3.3
retinoblastoma 3.3
MDM 3.3
XPG 3.3
lyssavirus 3.3
skin tumor 3.3
Autosomal dominant polycystic kidney disease 3.3
Leukemia 3.3
HPC 3.3
alcoholic pancreatitis 3.3
Myxoma 3.3
plasmacytoma 3.3
lymphoblastic leukemia 3.3
Ewing's sarcoma 3.3
Yersinia 3.3
degenerative disc disease 3.3
SM1 3.2
glucagonoma 3.2
acute myeloid leukemia 3.2
Testes 3.2
sarcoma 180 3.2
brain tumor 3.2
Shiga 3.2
threatened abortion 3.2
laryngeal cancer 3.2
gallbladder cancer 3.2
Testis 3.2
Testis 3.2
NPC 3.2
metastatic colon cancer 3.2
pediatric AML 3.2
nephrosis 3.2
PCD 3.2
cutaneous T-cell lymphoma 3.2
uveal melanoma 3.2
Diaphragm 3.2
lung cancer 3.2
metastatic gastric cancer 3.2
brain cancer 3.1
Shigella dysenteriae 3.1
laryngeal cancer 3.1
urinary tract obstruction 3.1
breast cancer 3.1
gastric cancer 3.1
TEC 3.1
Classical swine fever 3.1
Bovine viral diarrhea 3.1
carcinoma of the pancreas 3.1
CJD 3.1
seborrheic keratosis 3.1
colorectal cancer 3.1
melanoma 3.1
ovarian dysfunction 3.1
keratosis 3.0
bladder cancer 3.0
follicular lymphoma 3.0
Thomsen 3.0
NS3 3.0
SCID 3.0
lung carcinoma 3.0
adenocarcinoma 3.0
chromoblastomycosis 3.0
EL4 3.0
tumor vasculature 3.0
Smith-Lemli-Opitz syndrome 3.0
cancer 3.0
PTD 2.9
silicosis 2.9
intestinal cancer 2.9
HYP 2.9
ED2 2.9
tubular necrosis 2.9
childhood ALL 2.9
pseudotuberculosis 2.9
lymphoma 2.9
Rocky Mountain spotted fever 2.9
fetal hypoxia 2.9
bacterial infection 2.9
squamous cell carcinoma 2.9
liver fibrosis 2.9
tumor 2.9
chronic lymphocytic leukemia 2.9
PDP 2.9
Ovarian Cancer 2.8
SPS 2.8
small cell lung cancer 2.8
ATM 2.8
chronic lymphocytic leukemia 2.8
prolactinoma 2.8
papillary thyroid cancer 2.8
B virus infection 2.8
BDE 2.8
NHL 2.8
Pineal 2.8
Stomach 2.8
Stomach 2.8
Stomach 2.8
TAM 2.8
fibrosarcoma 2.8
postmenopausal bone loss 2.8
acute lymphoblastic leukemia 2.8
chronic myeloid leukemia 2.8
APL 2.8
AIDS dementia complex 2.8
chemical carcinogenesis 2.8
Ischemic stroke 2.7
renal cell carcinoma 2.7
achondroplasia 2.7
carcinogenesis 2.7
rheumatism 2.7
more...
Symptom
bradypnea 4.5
hyperemesis 4.0
Tenderness 3.6
loss of balance 3.4
skin damage 3.2
ataxic gait 3.1
halitosis 3.0
collapse 2.8
hyperoxia 2.6
menopausal symptoms 2.5
dry eye 2.4
hot flashes 2.1
splenomegaly 2.1
memory loss 2.0
sore throat 1.8
starvation 1.7
hypothermia 1.6
functional recovery 1.5
alexithymia 1.4
cachexia 1.3
HSA 0.6
exhaustion 0.4
insomnia 0.4
thinning 0.3
acute stress 0.0
seizures -0.3
flushing -0.5
respiratory distress -0.5
myalgia -0.5
tinnitus -0.5
diarrhea -0.6
dystonia -0.9
tremor -1.0
syncope -1.0
nausea and vomiting -1.0
dizziness -1.1
low back pain -1.1
back pain -1.4
weakness -1.4
sleepiness -1.5
erythema -1.5
overweight -1.5
acidity -1.7
abdominal pain -1.7
ataxia -1.8
headache -2.0
anesthesia -2.2
discomfort -2.3
nausea -2.3
discomfort -2.4
dyspnea -2.6
pain -3.2
Drug
Edratide 12.2
Lexatumumab 9.6
2-Iminobiotin 9.6
Alexidine 9.2
Zedoary 8.9
Mapatumumab 8.9
3,4-Dichloroisocoumarin 8.7
Bear bile 8.7
Methadone hydrochloride 8.7
Cupric sulfate 8.2
Citrus unshiu peel 8.1
Naftopidil 7.9
Mevastatin 7.8
Radicicol 7.7
Avasimibe 7.6
Flavopiridol 7.5
Motexafin gadolinium 7.5
Berberine chloride 7.4
Sodium ascorbate 7.4
2-Methoxyestradiol 7.4
Irofulven 7.2
Lonafarnib 7.0
Ilomastat 6.9
Bucillamine 6.9
Olomoucine 6.7
Peridinin 6.7
Hyperforin 6.7
Trabectedin 6.6
Bortezomib 6.5
CED 6.5
CA-074 6.4
Nafamostat mesilate 6.2
Dextran sulfate sodium 6.1
Revlimid 6.1
Zebularine 6.1
Swainsonine 5.8
Rasburicase 5.7
Batimastat 5.7
Batimastat 5.7
Mizoribine 5.6
Onconase 5.4
Epigallocatechin 5.4
Compound 18 5.4
Vorinostat 5.3
Emodin 5.3
Thioridazine 5.3
Etodolac 5.2
Arsenic trioxide 5.2
Cantor 5.2
Propidium 5.2
ROS 5.2
ID2 5.0
RBT 5.0
Emodin 5.0
Etoposide 4.8
p75 4.8
Artesunate 4.8
Bromelain 4.7
Glycyrrhiza 4.7
Casodex 4.6
Cetrorelix 4.6
Taxol 4.5
Dasatinib 4.5
BLyS 4.5
Tranilast 4.5
ADR 4.5
Triad 4.5
Olmesartan 4.5
Bosentan 4.5
Bosentan 4.5
Rolipram 4.4
Sorafenib 4.4
Poloxamer 188 4.4
Calcium chloride 4.4
Triad 4.4
Spiegel 4.3
IFN-beta 4.3
Pirfenidone 4.3
NVP 4.3
PFT 4.3
Rasburicase 4.2
Voltaren 4.2
CCL 4.2
Geranium 4.1
Areca 4.1
AMC 4.0
Perindopril 3.8
Colistin 3.8
-deoxyadenosine 3.8
Propofol 3.7
HPMPC 3.7
Limonene 3.7
TRM 3.7
Tao 3.6
Orlistat 3.6
Doyle 3.5
Rosiglitazone 3.5
Pravastatin 3.5
Ginseng 3.5
MDM 3.5
CoCl2 3.5
CoCl2 3.5
Vitamin B 3.5
Vinorelbine 3.5
Diclofenac sodium 3.4
Trifluoperazine 3.4
Oxaliplatin 3.3
OMP 3.3
CPT-11 3.3
Isoniazid 3.3
MRC 3.3
Hyaluronidase 3.2
Citric acid 3.2
Dihydro 3.2
Adalimumab 3.1
Troglitazone 3.1
Simvastatin 3.1
Salicylate 3.1
Docetaxel 3.0
Amiloride 3.0
Urokinase 2.9
Budesonide 2.9
VCR 2.9
Kainic acid 2.8
Lenalidomide 2.8
Rutin 2.8
Vitamin E 2.8
Lovastatin 2.8
Phosphatidylserine 2.8
Everolimus 2.7
Vitamin K 2.7
ALA 2.7
IL-2 2.7
Raloxifene 2.7
DHT 2.7
IFN-gamma 2.7
Mutagen 2.6
Erlotinib 2.6
DHT 2.6
Triclosan 2.6
Zoledronic acid 2.5
TAT 2.5
Ofloxacin 2.5
Xanthium 2.5
vitamin E 2.5
PTC 2.4
G-CSF 2.4
DBS 2.4
Adenosine triphosphate 2.4
Photofrin 2.3
DFP 2.3
Parkin 2.3
TTC 2.3
Parkin 2.3
Monensin 2.3
TAK 2.2
Vitamin A 2.2
Omeprazole 2.2
ADM 2.2
AraC 2.1
Ethanol 2.1
Doxycycline 2.1
Paraffin 2.1
Clopidogrel 2.1
Infliximab 2.0
Infliximab 2.0
Fragment 2.0
Gefitinib 2.0
RFP 1.9
Apomorphine 1.9
Glucagon 1.9
Ouabain 1.9
DPA 1.9
Angiotensin II 1.9
Fraction 1.9
ZnCl2 1.8
ZnCl2 1.8
Glutathione 1.8
ICI 1.8
Meth 1.8
ascorbate 1.8
Growth hormone 1.6
Amiloride 1.6
Growth hormone 1.6
BH4 1.6
Heme 1.6
VCR 1.6
Indomethacin 1.6
Cimetidine 1.5
TAC 1.5
Cimetidine 1.5
CTX 1.5
Retinoic acid 1.5
Activin 1.5
MAP 1.4
Fluorescein 1.3
CTX 1.3
CTX 1.3
EE2 1.3
Itraconazole 1.2
uPA 1.1
PCB 1.1
DMI 1.1
ACT 1.1
G418 1.1
Herceptin 1.0
Adriamycin 1.0
TMS 1.0
Monit 1.0
EPA 1.0
Silica 1.0
caffeine 1.0
Imatinib 0.9
pyridoxal phosphate 0.9
Nitric Oxide 0.8
Forskolin 0.8
ETS 0.8
Alliance 0.8
Fluorescein 0.8
Alanine 0.7
Rituximab 0.7
lysine 0.7
CSF 0.6
lactose 0.2
Portal 0.1
ABC 0.1
citric acid -0.1
Histamine -0.3
Asn -0.3
Bifidobacterium -0.3
CaCl2 -0.5
Spectrum -0.8
THF -0.8
ENT -0.9
Dermatol -1.2
Leaf -1.2
NADH -1.2
Nephron -1.4
ZnO -1.6
Gel -1.7
Dial -1.7
Nephron -1.9
Cardiovasc -2.0
Asthma -2.5
Enzyme
caspase-8 12.2
caspase-10 11.5
caspase-10 11.5
caspase-9 10.3
caspase-6 9.9
caspase-2 9.9
caspase-6 9.9
caspase-2 9.8
caspase-7 9.5
caspase-7 9.5
caspase-4 9.2
caspase-4 9.1
acylcarnitine hydrolase 8.8
caspase-3 8.7
caspase-11 8.6
caspase-5 8.5
caspase-11 8.5
caspase-5 8.5
lombricine kinase 7.9
Omi/HtrA2 7.9
PARP 7.7
caspase-1 7.5
AO1 7.0
adamalysin 6.9
DIPP 6.2
10-formyltetrahydrofolate dehydrogenase 6.1
TdT 6.1
3-hydroxy-3-methylglutaryl-CoA lyase 5.9
sphingomyelin synthase 5.9
lysyl-tRNA synthetase 5.7
granzyme B 5.7
neutral sphingomyelinase 5.6
AFR 5.6
aspartase 5.5
ceramidase 5.4
mu-calpain 5.3
m-calpain 5.3
IKK 5.3
ECH 5.3
cathepsin B 5.1
cdc2 5.0
sphingosine kinase 5.0
p100 5.0
mitogen-activated protein kinase 4.9
pseudouridine synthase 4.9
kynurenine aminotransferase 4.8
CYP46A1 4.7
GD3 synthase 4.6
kynurenine 3-monooxygenase 4.6
legumain 4.6
cathepsin C 4.6
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.5
HCS 4.5
MMP 4.5
glutaryl-CoA dehydrogenase 4.4
phosphatidylinositol 3-kinase 4.3
proteasome 4.3
coproporphyrinogen oxidase 4.2
farnesyltransferase 4.2
MEK 4.1
protein phosphatase 2A 4.1
cathepsin D 4.1
phosphoinositide 3-kinase 4.1
GSK 4.0
TSP-1 4.0
S-adenosylmethionine decarboxylase 4.0
farnesyltransferase 4.0
IMP dehydrogenase 3.9
inositol phosphatase 3.8
nucleotidase 3.8
DNA ligase 3.8
DNA ligase 3.8
ribonucleotide reductase 3.7
TOR 3.7
MEKK1 3.7
PDK1 3.6
MPP 3.6
ribonucleotide reductase 3.6
SNO 3.6
TACE 3.5
transaldolase 3.5
galactocerebrosidase 3.5
ERK 3.4
arginine deiminase 3.4
topoisomerase 3.4
KAT 3.4
myosin light chain kinase 3.4
succinate dehydrogenase 3.4
lactic acid dehydrogenase 3.4
adenosine kinase 3.3
topoisomerase 3.3
lactic acid dehydrogenase 3.3
gamma-glutamylcysteine synthetase 3.3
HMG-CoA synthase 3.3
glucosylceramide synthase 3.3
CAD 3.3
catalase 3.3
calcineurin 3.3
CAD 3.2
protein kinase 3.2
cathepsin S 3.2
lactate dehydrogenase 3.2
CAD 3.2
triphosphatase 3.2
superoxide dismutase 3.2
polo-like kinase 1 3.2
apyrase 3.2
TRS 3.2
paraoxonase 3.2
peroxiredoxin 3.1
glutathione reductase 3.1
P-glycoprotein 3.1
CNPase 3.1
p80 3.1
HK2 3.1
complex I 3.1
glycine decarboxylase 3.0
myrosinase 3.0
NADPH oxidase 3.0
CDH 3.0
15-lipoxygenase 3.0
NADPH oxidase 3.0
NOS 2.9
glutathione peroxidase 2.9
protein kinase C 2.9
focal adhesion kinase 2.9
AMP-activated protein kinase 2.9
cysteine synthase 2.9
15-hydroxyprostaglandin dehydrogenase 2.9
RNase 2.9
AMPK 2.9
factor C 2.9
endothelin-converting enzyme 2.9
DCF 2.8
luciferase 2.8
glutathione synthetase 2.8
MMP-3 2.8
cholesterol acyltransferase 2.8
argininosuccinate synthetase 2.8
cholesterol oxidase 2.8
RNase 2.8
deoxycytidine kinase 2.7
PGM 2.7
SOR 2.7
ornithine aminotransferase 2.7
ribonuclease 2.7
ribonuclease 2.7
insulin-degrading enzyme 2.7
CEP 2.6
AST 2.6
sialyltransferase 2.6
lactic acid dehydrogenase 2.6
sialyltransferase 2.6
sialyltransferase 2.6
aspartate aminotransferase 2.6
alanine aminotransferase 2.6
TAT 2.5
ubiquitin-protein ligase 2.5
SPS 2.5
methionine synthase 2.5
acyl-CoA synthetase 2.5
PKG 2.5
glutamine synthetase 2.5
PHD 2.4
glutathione S-transferase 2.4
beta-secretase 2.4
methionine synthase 2.4
ferrochelatase 2.3
NO synthase 2.3
DNase 2.3
GAS 2.3
PRE 2.3
calcium pump 2.2
bromelain 2.2
thymidine phosphorylase 2.2
MAP 2.1
CPT 2.1
ricin 2.1
5alpha-reductase 2.1
5alpha-reductase 2.1
thymidine kinase 2.1
MDR 2.1
matrix metalloproteinase 9 2.1
CEP 2.1
3-hydroxy-3-methylglutaryl-CoA reductase 2.1
GRK5 2.0
fumarase 2.0
AMPK 2.0
hyaluronidase 2.0
CPT 2.0
matrix metalloproteinase 2 2.0
TSA 2.0
uricase 1.9
transglutaminase 1.9
thioredoxin reductase 1.9
arginase 1.9
alpha-ketoglutarate dehydrogenase 1.9
acyl-CoA synthetase 1.9
BMT 1.8
neutrophil elastase 1.8
histone acetyltransferase 1.8
heme oxygenase 1.7
phenylalanine hydroxylase 1.7
purine nucleoside phosphorylase 1.7
indoleamine 2,3-dioxygenase 1.7
acetyl-CoA carboxylase 1.7
3-hydroxy-3-methylglutaryl coenzyme A reductase 1.7
histidine decarboxylase 1.7
tyrosine hydroxylase 1.7
MAT 1.6
CPT 1.6
phospholipase C 1.6
hyaluronidase 1.6
choline acetyltransferase 1.6
MIP 1.5
DNA methyltransferase 1.5
reverse transcriptase 1.5
paraoxonase 1.4
HSD 1.4
MAT 1.4
prostate-specific antigen 1.4
CD13 1.4
collagenase 1.3
cathepsin K 1.3
transcriptase 1.3
glutaminase 1.3
cathepsin L 1.2
CaMKII 1.2
xanthine oxidase 1.2
ornithine decarboxylase 1.1
NADH dehydrogenase 1.1
hormone-sensitive lipase 1.1
aldehyde dehydrogenase 1.1
aldehyde dehydrogenase 1.1
aldehyde dehydrogenase 1.1
aldehyde dehydrogenase 1.1
citrate synthase 1.1
creatine kinase 1.0
histidine kinase 1.0
ATPase 0.9
pectinase 0.9
adenosine deaminase 0.9
aldehyde dehydrogenase 0.9
adenosine deaminase 0.8
MDP 0.8
sialidase 0.8
asparaginase 0.8
APC 0.8
diaphorase 0.8
demethylase 0.8
peroxidase 0.7
glucokinase 0.7
neuraminidase 0.7
lipoxygenase 0.7
diaphorase 0.7
gamma-glutamyl transpeptidase 0.6
kallikrein 0.6
glucose-6-phosphatase 0.6
NQO1 0.6
endonuclease 0.6
phosphodiesterase 0.6
CYP3A4 0.6
furin 0.5
alkaline phosphatase 0.5
glyceraldehyde-3-phosphate dehydrogenase 0.5
CD10 0.5
papain 0.5
pyruvate dehydrogenase 0.4
RNA polymerase 0.4
pyruvate dehydrogenase 0.4
trypsin 0.4
acetylcholinesterase 0.4
urokinase-type plasminogen activator 0.4
thymidylate synthase 0.4
chymotrypsin 0.4
S1 nuclease 0.3
PDE 0.3
enolase 0.3
phosphofructokinase 0.3
NADPH-diaphorase 0.3
proteinase K 0.2
guanylate cyclase 0.1
acid phosphatase 0.1
glutamate dehydrogenase 0.1
glyceraldehyde-3-phosphate dehydrogenase 0.1
glutamate dehydrogenase 0.1
glyceraldehyde-3-phosphate dehydrogenase 0.1
cytochrome oxidase 0.1
PAH 0.1
glutamate dehydrogenase 0.1
plasmin 0.0
elastase 0.0
ACE 0.0
malate dehydrogenase 0.0
glyceraldehyde-3-phosphate dehydrogenase -0.0
phospholipase A2 -0.0
adenylate cyclase -0.0
kinesin -0.1
alpha-amylase -0.2
monoamine oxidase -0.2
glucose oxidase -0.2
pyruvate dehydrogenase -0.2
phosphorylase -0.3
glyceraldehyde-3-phosphate dehydrogenase -0.3
renin -0.4
cholinesterase -0.4
ATP synthase -0.6
carbonic anhydrase -0.7
pepsin -0.9
lipase -1.0
ACS -1.1
lysozyme -1.2
tissue plasminogen activator -1.3
thrombin -1.8
Compound
estra-1,3,5(10)-trien-17-ol 12.2
4-chloro-N-methylbenzamide 11.2
Justicidin A 10.9
Cephalochromin 10.6
Glucoraphenin 10.6
C14H21N3O2 10.6
C14H21N3O2 10.6
C14H21N3O2 10.6
C14H21N3O2 10.6
24-Hydroxycholesterol 10.6
C14H21N3O2 10.6
C14H21N3O2 10.2
Dihydrosanguinarine 10.2
Sarcophine 10.2
Cephalostatin 1 10.0
Tigogenin 9.9
C14H21N3O2 9.9
2-hexadecanol 9.9
Saucernetin 9.9
C14H21N3O2 9.9
alpha-Santalol 9.6
Gartanin 9.6
C14H21N3O2 9.6
2,5-Dihydroxyacetophenone 9.6
Raddeanin A 9.5
Lupulone 9.4
Deltonin 9.4
methyl 2-benzoylbenzoate 9.4
Linoelaidic acid 9.4
C14H21N3O2 9.2
androst-2-en-17-one 9.2
Sinularin 9.2
Codeinone 9.2
Rocaglamide 9.1
PHPS 9.0
Didodecyldimethylammonium bromide 9.0
hydroxymethylphosphonic acid 9.0
Tectochrysin 8.9
Nomilin 8.9
2,4-dimethylpyridine 8.9
Dihydrochalcone 8.9
Bufotalin 8.9
N-hydroxybutanamide 8.9
cis-Jasmone 8.7
2-hydroxy-1-propanesulfonic acid 8.7
Chelidonine 8.7
7-Ketocholesterol 8.7
N-hydroxybutanamide 8.6
3,4-dimethylpyridine 8.6
Dicentrine 8.6
taurolithocholate 3-sulfate 8.5
Bullatacin 8.5
Tricetin 8.5
Ginkgetin 8.4
Morphinone 8.4
Methadone hydrochloride 8.4
Piperlonguminine 8.4
Harmol 8.3
2-oxopropanamide 8.3
Ovatodiolide 8.3
Phytosphingosine 8.2
Decursin 8.0
Ver A 8.0
N-hydroxybenzamide 7.9
Isofraxidin 7.9
Decursinol 7.9
Borrelidin 7.8
2-phenylnaphthalene 7.8
Borrelidin 7.7
Phenethyl isothiocyanate 7.7
Bongkrekic acid 7.6
Sulfuretin 7.5
Liriodenine 7.4
Sanguinarine 7.4
Solamargine 7.4
2-Methoxyestradiol 7.4
Cadinene 7.4
LLY 7.4
Scutellarein 7.4
Embelin 7.4
Isoalantolactone 7.3
Berberine chloride 7.3
Celastrol 7.3
Morusin 7.3
Bullatacin 7.3
Gentiopicroside 7.2
3-Deazaadenosine 7.2
Imexon 7.2
Dioscin 7.2
Dioscin 7.2
3,5-dimethylpyridine 7.2
Benzohydroxamic acid 7.2
Acacetin 7.2
Neoxanthin 7.2
Guggulsterone 7.2
Janus Green B 7.2
benzo[c]phenanthridine 7.2
Wedelolactone 7.1
Boswellic acid 7.1
Boldine 7.1
OLN 7.1
1-phenyl-1H-pyrazole 7.1
Chrysophanol 7.0
Geranylgeraniol 7.0
1,3-benzoxazole 7.0
Aloe-emodin 7.0
Geranylgeranylacetone 7.0
Costunolide 7.0
Chrysophanol 7.0
Bisphenol A diglycidyl ether 7.0
Cordycepin 7.0
Cordycepin 7.0
Cordycepin 6.9
Cobaltous chloride 6.9
Humulene 6.9
Taurochenodeoxycholate 6.9
Oleandrin 6.9
Ursolic acid 6.9
Propyl gallate 6.9
Pheophorbide a 6.9
Anisomycin 6.9
Pheophorbide a 6.9
chelidonine 6.8
Pyrogallol 6.8
Oridonin 6.8
Fisetin 6.8
Blue Tetrazolium 6.8
Glycyrrhetinic acid 6.8
Poly C 6.7
Gambogic acid 6.7
Angelicin 6.7
Hyperforin 6.7
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 6.7
beta-Lapachone 6.7
Evodiamine 6.7
Methylguanidine 6.7
Geraniin 6.7
Benzyl isothiocyanate 6.7
Noscapine 6.7
NOXA 6.6
NPIP 6.6
Helenalin 6.6
Evodiamine 6.6
Epichlorohydrin 6.6
Rottlerin 6.6
Esculetin 6.5
Hispidulin 6.5
Tanshinone 6.5
Hyperoside 6.5
celastrol 6.5
Bufalin 6.5
Rottlerin 6.5
Rottlerin 6.5
Diosgenin 6.5
Cytochrome c 6.5
Glycyrrhetinic acid 6.5
Nodularin 6.5
Ginsenoside Re 6.5
Danthron 6.4
dUTP 6.4
Alantolactone 6.4
Tolmetin 6.4
ADP-ribose 6.4
Pyran 6.4
Fenvalerate 6.4
HFr 6.4
Asiatic acid 6.3
dUDP 6.3
Calpeptin 6.3
1-tetradecanol 6.3
Psychosine 6.3
Indirubin 6.3
Triptolide 6.2
Apigenin 6.2
Tetrandrine 6.2
Tetrandrine 6.2
Tetrandrine 6.2
Tetrandrine 6.2
Sulforaphane 6.2
4-Methylumbelliferone 6.2
10-Hydroxycamptothecin 6.2
T-2 mycotoxin 6.2
Dihydromyricetin 6.1
Anisodamine 6.1
5H-pyrido[4,3-b]indole 6.1
Delphinidin 6.1
ASC 6.1
Fusaric acid 6.1
Fusaric acid 6.1
Garcinol 6.1
Phloroglucinol 6.1
Fusaric acid 6.1
DCB 6.0
DCB 6.0
Tangeretin 6.0
ML-236B 6.0
Cucurbitacin B 6.0
Betulinic acid 6.0
5-Aza-2'-deoxycytidine 6.0
Luteolin 5.9
Manumycin 5.9
Phloroglucinol 5.9
benzenesulfonyl fluoride 5.9
Escin 5.9
Xanthohumol 5.9
Imperatorin 5.9
Lupeol 5.9
Escin 5.9
Deguelin 5.9
COA 5.9
DCB 5.8
Glycolaldehyde 5.8
Sulindac 5.8
CMK 5.8
Hoechst 33342 5.8
Equol 5.8
Geldanamycin 5.8
Canthaxanthin 5.8
TOCP 5.8
IEA 5.8
Shikonin 5.8
CUE 5.7
Rhein 5.7
1-Methyl-4-phenylpyridinium 5.7
Phthalocyanine 5.7
2-cyclopenten-1-one 5.7
Fucoidan 5.7
Cepharanthine 5.7
Piceatannol 5.7
N-(4-hydroxyphenyl)retinamide 5.7
Homoharringtonine 5.6
Hesperetin 5.6
Crocin 5.6
Tyrosol 5.6
Baicalin 5.6
Propidium iodide 5.6
indole-3-carbinol 5.6
Swainsonine 5.6
Jasplakinolide 5.6
DCB 5.6
Flavone 5.6
Nonylphenol 5.5
Deoxynivalenol 5.5
Cyt 5.5
Nefazodone 5.5
cinnoline 5.5
Parthenolide 5.5
Copper sulfate 5.5
Magnolol 5.5
TCTP 5.5
Ginkgolide B 5.5
Poly(I:C) 5.4
Wogonin 5.4
1,2,3,4-tetrahydroquinoline 5.4
1,2,3,4-tetrahydroquinoline 5.4
Stains-all 5.4
Bicalutamide 5.4
Diallyl 5.4
Tumor Necrosis Factor 5.4
Rhodamine 123 5.4
Chloroacetaldehyde 5.4
DCB 5.4
SDZ PSC 833 5.4
Tannin 5.4
MTT 5.4
Salinomycin 5.4
2-butenal 5.4
DBN 5.3
p-Coumaric acid 5.3
PGJ2 5.3
Zinc protoporphyrin 5.3
Parthenolide 5.3
(-)-Epigallocatechin 5.3
Emodin 5.3
Matrine 5.3
Matrine 5.3
Baicalein 5.3
Stigmasterol 5.3
Matrine 5.3
Ellipticine 5.3
N-acetylcysteine 5.2
Berberine 5.2
Nortriptyline 5.2
Galangin 5.2
Silymarin 5.2
Exotoxin 5.2
S-allylcysteine 5.2
Oxymatrine 5.2
9H-xanthen-9-one 5.2
maslinic acid 5.2
Usnic acid 5.2
15(S)-HETE 5.2
Farnesyl diphosphate 5.2
Taxifolin 5.2
Formononetin 5.1
APO 5.1
DAU 5.1
Keloid 5.1
Se-methylselenocysteine 5.1
Naringenin 5.1
PIPES 5.1
PIPES 5.1
PIPES 5.1
Harmaline 5.1
dATP 5.1
Benzothiazole 5.0
Biochanin A 5.0
LY 294002 5.0
1,2,4-benzenetriol 5.0
Naringenin 5.0
TNF 5.0
Gliotoxin 5.0
Gliotoxin 5.0
Hypericin 5.0
DAU 5.0
Caryophyllene 5.0
Chrysin 5.0
Oleanolic acid 4.9
decarboxylated S-adenosylmethionine 4.9
DCVC 4.9
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