Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.61 (
caspase-8
)
6,833
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase and RIP adapter with death domain
12.2
EFR3 homolog B
12.2
NADH-ubiquinone oxidoreductase B18 subunit
12.2
Death associated protein 3
12.2
caspase-8
11.8
C4orf22
11.2
G1/S-specific cyclin E2
11.2
Sal-like 4 (Drosophila)
11.2
sorting nexin 7
11.2
Apoptotic peptidase activating factor 1
11.2
FLICE
11.0
Fas-associated death domain protein
10.9
FADD
10.9
DEDD2
10.9
c-FLIP
10.7
Bid
10.6
FLICE-associated huge protein
10.6
DOPEY1
10.6
inhibitor of growth family, member 3
10.6
PTPRK protein
10.6
more...
Disease
LACH
10.6
HMN7B
10.2
Acute glaucoma
9.5
DFNB59
8.3
methionine synthase deficiency
8.2
autoimmune lymphoproliferative syndrome
8.0
AIDS cholangiopathy
7.8
Reovirus infection
7.7
Corneal infection
7.3
amok
7.1
KRS
7.0
AD5
7.0
salivary gland adenoid cystic carcinoma
6.9
salivary gland cancer
6.9
childhood rhabdomyosarcoma
6.6
mouse leukemia P388
6.6
VED
6.5
FAS
6.5
CYLD
6.4
salivary gland adenocarcinoma
6.4
more...
Symptom
bradypnea
4.5
hyperemesis
4.0
Tenderness
3.6
loss of balance
3.4
skin damage
3.2
ataxic gait
3.1
halitosis
3.0
collapse
2.8
hyperoxia
2.6
menopausal symptoms
2.5
dry eye
2.4
hot flashes
2.1
splenomegaly
2.1
memory loss
2.0
sore throat
1.8
starvation
1.7
hypothermia
1.6
functional recovery
1.5
alexithymia
1.4
cachexia
1.3
more...
Drug
Edratide
12.2
Lexatumumab
9.6
2-Iminobiotin
9.6
Alexidine
9.2
Zedoary
8.9
Mapatumumab
8.9
3,4-Dichloroisocoumarin
8.7
Methadone hydrochloride
8.7
Bear bile
8.7
Cupric sulfate
8.2
Citrus unshiu peel
8.1
Naftopidil
7.9
Mevastatin
7.8
Radicicol
7.7
Avasimibe
7.6
Flavopiridol
7.5
Motexafin gadolinium
7.5
Sodium ascorbate
7.4
Berberine chloride
7.4
2-Methoxyestradiol
7.4
more...
Enzyme
caspase-8
12.2
caspase-10
11.5
caspase-10
11.5
caspase-9
10.3
caspase-6
9.9
caspase-2
9.9
caspase-6
9.9
caspase-2
9.8
caspase-7
9.5
caspase-7
9.5
caspase-4
9.2
caspase-4
9.1
acylcarnitine hydrolase
8.8
caspase-3
8.7
caspase-11
8.6
caspase-5
8.5
caspase-11
8.5
caspase-5
8.5
lombricine kinase
7.9
Omi/HtrA2
7.9
more...
Compound
estra-1,3,5(10)-trien-17-ol
12.2
4-chloro-N-methylbenzamide
11.2
Justicidin A
10.9
24-Hydroxycholesterol
10.6
C14H21N3O2
10.6
C14H21N3O2
10.6
Cephalochromin
10.6
C14H21N3O2
10.6
C14H21N3O2
10.6
Glucoraphenin
10.6
C14H21N3O2
10.6
Dihydrosanguinarine
10.2
Sarcophine
10.2
C14H21N3O2
10.2
Cephalostatin 1
10.0
C14H21N3O2
9.9
C14H21N3O2
9.9
2-hexadecanol
9.9
Tigogenin
9.9
Saucernetin
9.9
more...