Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.61 (caspase-8)
6,833 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase and RIP adapter with death domain 12.2
EFR3 homolog B 12.2
NADH-ubiquinone oxidoreductase B18 subunit 12.2
Death associated protein 3 12.2
caspase-8 11.8
C4orf22 11.2
G1/S-specific cyclin E2 11.2
Sal-like 4 (Drosophila) 11.2
sorting nexin 7 11.2
Apoptotic peptidase activating factor 1 11.2
FLICE 11.0
Fas-associated death domain protein 10.9
FADD 10.9
DEDD2 10.9
c-FLIP 10.7
Bid 10.6
FLICE-associated huge protein 10.6
DOPEY1 10.6
inhibitor of growth family, member 3 10.6
PTPRK protein 10.6
more...
Disease
LACH 10.6
HMN7B 10.2
Acute glaucoma 9.5
DFNB59 8.3
methionine synthase deficiency 8.2
autoimmune lymphoproliferative syndrome 8.0
AIDS cholangiopathy 7.8
Reovirus infection 7.7
Corneal infection 7.3
amok 7.1
KRS 7.0
AD5 7.0
salivary gland adenoid cystic carcinoma 6.9
salivary gland cancer 6.9
childhood rhabdomyosarcoma 6.6
mouse leukemia P388 6.6
VED 6.5
FAS 6.5
CYLD 6.4
salivary gland adenocarcinoma 6.4
more...
Symptom
bradypnea 4.5
hyperemesis 4.0
Tenderness 3.6
loss of balance 3.4
skin damage 3.2
ataxic gait 3.1
halitosis 3.0
collapse 2.8
hyperoxia 2.6
menopausal symptoms 2.5
dry eye 2.4
hot flashes 2.1
splenomegaly 2.1
memory loss 2.0
sore throat 1.8
starvation 1.7
hypothermia 1.6
functional recovery 1.5
alexithymia 1.4
cachexia 1.3
more...
Drug
Edratide 12.2
Lexatumumab 9.6
2-Iminobiotin 9.6
Alexidine 9.2
Zedoary 8.9
Mapatumumab 8.9
3,4-Dichloroisocoumarin 8.7
Methadone hydrochloride 8.7
Bear bile 8.7
Cupric sulfate 8.2
Citrus unshiu peel 8.1
Naftopidil 7.9
Mevastatin 7.8
Radicicol 7.7
Avasimibe 7.6
Flavopiridol 7.5
Motexafin gadolinium 7.5
Sodium ascorbate 7.4
Berberine chloride 7.4
2-Methoxyestradiol 7.4
more...
Enzyme
caspase-8 12.2
caspase-10 11.5
caspase-10 11.5
caspase-9 10.3
caspase-6 9.9
caspase-2 9.9
caspase-6 9.9
caspase-2 9.8
caspase-7 9.5
caspase-7 9.5
caspase-4 9.2
caspase-4 9.1
acylcarnitine hydrolase 8.8
caspase-3 8.7
caspase-11 8.6
caspase-5 8.5
caspase-11 8.5
caspase-5 8.5
lombricine kinase 7.9
Omi/HtrA2 7.9
more...
Compound
estra-1,3,5(10)-trien-17-ol 12.2
4-chloro-N-methylbenzamide 11.2
Justicidin A 10.9
24-Hydroxycholesterol 10.6
C14H21N3O2 10.6
C14H21N3O2 10.6
Cephalochromin 10.6
C14H21N3O2 10.6
C14H21N3O2 10.6
Glucoraphenin 10.6
C14H21N3O2 10.6
Dihydrosanguinarine 10.2
Sarcophine 10.2
C14H21N3O2 10.2
Cephalostatin 1 10.0
C14H21N3O2 9.9
C14H21N3O2 9.9
2-hexadecanol 9.9
Tigogenin 9.9
Saucernetin 9.9
more...