Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.61 (caspase-8)
 6,833 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-8 6750
caspase-3 3145
caspase-9 1986
Bcl-2 1477
Fas 1456
cytochrome c 1210
Bid 785
tumor necrosis factor 645
p53 631
Mol 602
PARP 571
FADD 528
Sep 487
TNF 421
TRAIL 394
CD95 385
FLICE 373
FasL 333
Fas ligand 325
cytokine 289
more...
Disease
cancer 1812
tumor 1077
leukemia 346
breast cancer 298
hepatocellular carcinoma 224
MCF 203
carcinoma 201
tumor growth 201
prostate cancer 152
colon cancer 152
lung cancer 137
GSH 127
melanoma 124
ischemia 122
neuroblastoma 121
adenocarcinoma 117
lymphoma 116
multiple myeloma 103
glioma 100
colorectal cancer 95
more...
Symptom
collapse 43
starvation 17
seizures 14
hypothermia 11
splenomegaly 9
diarrhea 8
functional recovery 8
hyperoxia 7
pain 6
anesthesia 5
exhaustion 4
insomnia 3
respiratory distress 3
thinning 3
weakness 3
memory loss 3
skin damage 3
headache 3
dry eye 3
cachexia 3
more...
Drug
ROS 149
IL-2 41
IFN-gamma 39
Bortezomib 29
Dermatol 25
p75 23
vitamin E 21
lysine 20
ascorbate 17
Taxol 16
Monit 15
IFN-beta 13
CED 11
Cardiovasc 11
Arsenic trioxide 10
CSF 10
ADR 10
MAP 9
caffeine 9
Ethanol 9
more...
Enzyme
caspase-8 6833
caspase-3 3091
caspase-9 1965
PARP 625
mitogen-activated protein kinase 613
caspase-1 245
ERK 223
protein kinase 164
caspase-2 156
caspase-2 155
caspase-7 142
caspase-7 138
proteasome 123
superoxide dismutase 115
caspase-10 114
catalase 114
caspase-10 110
caspase-6 99
caspase-6 96
protein kinase C 80
more...
Compound
DNA 1148
oxygen 674
Dec 527
TNF 421
MTT 288
cysteine 249
Asp 177
MDA 157
dUTP 142
GSH 130
GSH 130
calcium 127
iodine 124
alanine 113
ADP-ribose 107
Clin 102
ATP 90
nitric oxide 90
N-acetylcysteine 88
glucose 87
more...