EC:3.4.22.60 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:3.4.22.60 (caspase-7)
920 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
caspase-3	539
caspase-9	230
PARP	163
Bcl-2	151
caspase-8	146
cytochrome c	109
p53	97
Mol	90
poly(ADP-ribose) polymerase	68
Sep	59
endoplasmic reticulum	57
caspase 7	51
p21	49
Fas	48
Bid	40
annexin V	38
p38	34
inhibitor of apoptosis	32
XIAP	30
JNK	27
ERK	26
calpain	25
poly (ADP-ribose) polymerase	25
bax	25
CPP32	24
TNF	23
cytokine	23
Bak	22
survivin	21
bcl-2	21
cyclin D1	21
p27	20
AKT	20
MAPK	20
CHOP	20
GRP78	20
Smac	18
ERK1	18
granzyme B	17
Apaf-1	17
Mcl-1	16
ATP	16
ADP	16
mTOR	16
LC3	16
glucose-regulated protein	15
caspase 6	15
PARP-1	14
ROS	14
proteasome	14
CDK2	13
Tumor necrosis factor	13
FasL	13
c-Jun	13
cysteine protease	13
tumor necrosis factor	12
CMH-1	12
PERK	12
Fas ligand	12
FADD	11
apoptosis-inducing factor	11
X-linked inhibitor of apoptosis protein	11
p65	11
estrogen receptor	11
cytochrome	10
PI3K	10
anti-apoptotic protein	10
MEK	10
NMR	10
pro-apoptotic protein	10
cIAP2	10
IAP2	10
CDK6	10
histone deacetylase	10
DIABLO	10
tyrosine kinase	10
CDK4	9
proliferating cell nuclear antigen	9
CD95	9
PC-3	9

Disease
cancer	258
tumor	150
MCF	119
breast cancer	105
carcinoma	35
tumor growth	30
colon cancer	27
leukemia	24
hepatocellular carcinoma	23
carcinogenesis	22
prostate cancer	20
lung cancer	19
B-cell lymphoma	19
adenocarcinoma	18
colorectal cancer	17
glioma	17
tumorigenesis	15
Alzheimer's disease	13
ischemia	12
squamous cell carcinoma	12
lymphoma	12
melanoma	10
neuroblastoma	10
tumor progression	10
acute myeloid leukemia	9
pancreatic cancer	9
gastric cancer	9
non-small cell lung cancer	8
renal cell carcinoma	8
liver cancer	8
Blocking	8
cervical cancer	8
esophageal cancer	7
esophageal cancer	7
GSH	7
retinoblastoma	7
Parkinson's disease	6
stroke	6
multiple myeloma	6
Kaposi's sarcoma	6
liver cancer	6
infectious diseases	5
glioblastoma	5
solid tumor	5
influenza	5
Legionella	5
skin cancer	5
ovarian cancer	5
acute promyelocytic leukemia	5
bladder cancer	5
MTS	5
AGS	5
DDP	5
HIV	4
glioblastoma multiforme	4
hepatitis C	4
chronic myeloid leukemia	4
Hepatocellular carcinoma	4
epithelial ovarian cancer	4
diabetes	4
lung carcinoma	4
fibrosarcoma	4
virus infection	4
myocardial ischemia	4
Huntington's disease	3
amyotrophic lateral sclerosis	3
cowpox	3
metastases	3
liver fibrosis	3
sepsis	3
hepatitis	3
myocardial infarction	3
pneumonia	3
Infection	3
osteosarcoma	3
heart failure	3
muscular atrophy	3
sepsis	3
AIDS	3
cerebral ischemia	3

Enzyme
caspase-7	920
caspase-7	896
caspase-3	551
caspase-9	228
PARP	176
caspase-8	142
caspase-6	77
mitogen-activated protein kinase	75
caspase-6	68
caspase-1	54
caspase-2	38
caspase-2	38
ERK	34
protein kinase	18
granzyme B	17
proteasome	14
MEK	14
caspase-4	13
cdc2	12
protein kinase C	12
caspase-4	11
focal adhesion kinase	10
superoxide dismutase	9
catalase	9
lactate dehydrogenase	7
MAP	6
ACS	6
caspase-10	5
GSK	5
glutathione peroxidase	5
glutathione S-transferase	5
caspase-10	5
AMP-activated protein kinase	4
NADPH oxidase	4
glutathione reductase	4
endonuclease	4
RNase	4
aspartate aminotransferase	4
caspase-5	4
trypsin	4
alanine aminotransferase	4
ATPase	4
luciferase	4
caspase-11	3
myosin light chain kinase	3
NADPH oxidase	3
phosphoinositide 3-kinase	3
cathepsin G	3
RNase	3
caspase-11	3
elastase	3
creatine kinase	3
thrombin	3
ECH	3
calcineurin	3
DNase	3
cathepsin D	3
Omi/HtrA2	3
reverse transcriptase	3
topoisomerase	3
phospholipase C	3
m-calpain	3
topoisomerase	3
caspase-5	2
peroxiredoxin	2
AMPK	2
P-glycoprotein	2
NQO1	2
CAD	2
thymidylate synthase	2
complex I	2
CAD	2
DNA methyltransferase	2
sphingosine kinase	2
prolyl hydroxylase	2
succinate dehydrogenase	2
DNA polymerase	2
IKK	2
cathepsin B	2
mu-calpain	2