Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.60 (caspase-7)
 920 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 539
caspase-9 230
PARP 163
Bcl-2 151
caspase-8 146
cytochrome c 109
p53 97
Mol 90
poly(ADP-ribose) polymerase 68
Sep 59
endoplasmic reticulum 57
caspase 7 51
p21 49
Fas 48
Bid 40
annexin V 38
p38 34
inhibitor of apoptosis 32
XIAP 30
JNK 27
ERK 26
bax 25
calpain 25
poly (ADP-ribose) polymerase 25
CPP32 24
cytokine 23
TNF 23
Bak 22
cyclin D1 21
survivin 21
bcl-2 21
MAPK 20
AKT 20
GRP78 20
CHOP 20
p27 20
Smac 18
ERK1 18
Apaf-1 17
granzyme B 17
more...
Disease
cancer 258
tumor 150
MCF 119
breast cancer 105
carcinoma 35
tumor growth 30
colon cancer 27
leukemia 24
hepatocellular carcinoma 23
carcinogenesis 22
prostate cancer 20
B-cell lymphoma 19
lung cancer 19
adenocarcinoma 18
glioma 17
colorectal cancer 17
tumorigenesis 15
Alzheimer's disease 13
squamous cell carcinoma 12
lymphoma 12
ischemia 12
melanoma 10
neuroblastoma 10
tumor progression 10
pancreatic cancer 9
gastric cancer 9
acute myeloid leukemia 9
renal cell carcinoma 8
non-small cell lung cancer 8
liver cancer 8
cervical cancer 8
Blocking 8
esophageal cancer 7
esophageal cancer 7
GSH 7
retinoblastoma 7
multiple myeloma 6
stroke 6
Parkinson's disease 6
liver cancer 6
more...
Symptom
starvation 3
seizures 2
functional recovery 2
hypothermia 1
hypercapnia 1
hyperoxia 1
pain 1
headache 1
neuralgia 1
erythema 1
Drug
ROS 14
lysine 8
MAP 6
CED 6
IFN-gamma 5
Arsenic trioxide 4
Sorafenib 3
IL-2 3
Taxol 3
ICI 2
AMC 2
CTX 2
IFN-beta 2
ZnO 2
Dermatol 2
ACT 2
NVP 2
ADR 1
TFT 1
Fulvestrant 1
Compound 18 1
Estrogens 1
Nitric Oxide 1
CPT-11 1
Ketoconazole 1
Lovastatin 1
PFT 1
Epigallocatechin 1
Biopolymers 1
Adriamycin 1
Cardiovasc 1
Monensin 1
FAD 1
Phosphatidylserine 1
Rosiglitazone 1
Monit 1
Nephron 1
Parkin 1
Propofol 1
Asn 1
more...
Enzyme
caspase-7 920
caspase-7 896
caspase-3 551
caspase-9 228
PARP 176
caspase-8 142
caspase-6 77
mitogen-activated protein kinase 75
caspase-6 68
caspase-1 54
caspase-2 38
caspase-2 38
ERK 34
protein kinase 18
granzyme B 17
MEK 14
proteasome 14
caspase-4 13
protein kinase C 12
cdc2 12
caspase-4 11
focal adhesion kinase 10
superoxide dismutase 9
catalase 9
lactate dehydrogenase 7
ACS 6
MAP 6
caspase-10 5
glutathione peroxidase 5
caspase-10 5
glutathione S-transferase 5
GSK 5
endonuclease 4
alanine aminotransferase 4
NADPH oxidase 4
trypsin 4
glutathione reductase 4
caspase-5 4
RNase 4
ATPase 4
more...
Compound
DNA 155
Dec 77
oxygen 69
cysteine 49
Asp 43
MDA 34
MTT 33
ADP-ribose 26
TNF 23
glucose 23
calcium 20
ADP 18
iodine 17
dUTP 16
ADP 16
ADP 16
ATP 16
tyrosine 15
alanine 14
sodium 13
bromide 13
serine 12
hydrogen 11
N-acetylcysteine 10
MEK 10
aldehyde 9
aldehyde 9
Clin 9
lysine 9
water 8
zinc 8
acridine 8
Hoechst 33342 8
GSH 7
aspartic acid 7
aspartic acid 7
GSH 7
aspartic acid 7
boron 7
dATP 7
more...