Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.56 (caspase-3)
 35,750 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 0.764
caspase-9 0.067
Bcl-2 0.053
caspase-8 0.032
PARP 0.024
cytochrome c 0.020
CPP32 0.013
annexin V 0.008
poly(ADP-ribose) polymerase 0.008
Bid 0.006
poly (ADP-ribose) polymerase 0.006
Fas 0.005
p53 0.004
bax 0.003
Bax protein 0.003
XIAP 0.003
anti-apoptotic protein 0.003
Apaf-1 0.003
bcl-2 0.002
survivin 0.002
apoptosis-inducing factor 0.002
p38 0.002
JNK 0.002
pro-apoptotic protein 0.002
Smac 0.002
ROS 0.002
p21 0.002
Bak 0.002
AIF 0.002
BAX 0.001
Mcl-1 0.001
inhibitor of apoptosis 0.001
PARP-1 0.001
ICAD 0.001
FasL 0.001
PI3K 0.001
X-linked inhibitor of apoptosis protein 0.001
LC3 0.001
GSH 0.001
TNF 0.001
superoxide dismutase 0.001
calpain 0.001
Fas ligand 0.001
Bcl-X 0.001
tumor necrosis factor 0.001
AKT 0.001
FADD 0.001
cytochrome 0.001
MAPK 0.001
apoptosis-related protein 0.001
lactate dehydrogenase 0.001
ERK1 0.001
c-Jun 0.001
cyclin D1 0.001
ERK 0.001
TdT 0.001
GRP78 0.001
endonuclease G 0.001
DIABLO 0.001
cyclin B1 0.001
Beclin-1 0.001
caspase-activated DNase 0.001
C/EBP homologous protein 0.001
inducible nitric oxide synthase 0.001
p65 0.001
proliferating cell nuclear antigen 0.001
CHOP 0.001
TRAIL 0.001
catalase 0.001
CD95 0.001
p27 0.001
ICE 0.001
glutathione peroxidase 0.000
protein kinase B 0.000
LDH 0.000
p38 mitogen-activated protein kinase 0.000
Mol 0.000
extracellular signal-regulated kinase 0.000
heme oxygenase-1 0.000
mTOR 0.000
more...
Disease
cancer 0.001
GSH 0.001
B-cell lymphoma 0.001
tumor 0.001
ischemia 0.001
tumor growth 0.001
MCF 0.001
cerebral ischemia 0.001
neuroblastoma 0.000
leukemia 0.000
colon cancer 0.000
hepatocellular carcinoma 0.000
breast cancer 0.000
Alzheimer's disease 0.000
DDP 0.000
carcinoma 0.000
AGS 0.000
osteosarcoma 0.000
acute promyelocytic leukemia 0.000
MTS 0.000
lung cancer 0.000
prostate cancer 0.000
Parkinson's disease 0.000
glioma 0.000
glioblastoma 0.000
gastric cancer 0.000
cervical cancer 0.000
liver cancer 0.000
melanoma 0.000
adenocarcinoma 0.000
ovarian cancer 0.000
non-small cell lung cancer 0.000
colorectal cancer 0.000
renal ischemia 0.000
liver cancer 0.000
pancreatic cancer 0.000
tumorigenesis 0.000
carcinogenesis 0.000
squamous cell carcinoma 0.000
brain edema 0.000
myocardial ischemia 0.000
Osteosarcoma 0.000
Osteosarcoma 0.000
FAS 0.000
stroke 0.000
pheochromocytoma 0.000
retinoblastoma 0.000
diabetes 0.000
memory impairment 0.000
chronic myeloid leukemia 0.000
lymphoma 0.000
hyperglycemia 0.000
Pineal 0.000
multiple myeloma 0.000
diabetic cardiomyopathy 0.000
bladder cancer 0.000
myeloid leukemia 0.000
CEM 0.000
oral cancer 0.000
ATM 0.000
Middle cerebral artery occlusion 0.000
lung carcinoma 0.000
Hepatocellular carcinoma 0.000
CMH1 0.000
liver fibrosis 0.000
cognitive impairment 0.000
Blocking 0.000
Huntington's disease 0.000
diabetic nephropathy 0.000
acute myeloid leukemia 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
Intestinal ischemia 0.000
solid tumor 0.000
subarachnoid hemorrhage 0.000
tumor progression 0.000
SCID 0.000
Glioblastoma 0.000
Bovine tritrichomonosis 0.000
cerebral infarction 0.000
more...
Symptom
collapse 0.000
functional recovery 0.000
starvation 0.000
hyperoxia 0.000
seizures 0.000
hypothermia 0.000
skin damage 0.000
memory loss 0.000
bradykinesia 0.000
Chronic pelvic pain syndrome 0.000
anesthesia 0.000
Motor dysfunction 0.000
not coping 0.000
sinus congestion 0.000
Scratch 0.000
respiratory distress 0.000
cachexia 0.000
diarrhea 0.000
Ear swelling 0.000
Circling 0.000
thinning 0.000
neurological disability 0.000
Inflammatory pain 0.000
stomach pain 0.000
Behavioral symptoms 0.000
Anoxia 0.000
acute stress 0.000
disturbed balance 0.000
incoordination 0.000
infant diarrhea 0.000
HSA 0.000
pain 0.000
Acute urinary retention 0.000
Joint hypermobility 0.000
ataxia 0.000
POA 0.000
startle reaction 0.000
Neuropathic pain 0.000
dry eye 0.000
Tenderness 0.000
weakness 0.000
impaired motor coordination 0.000
loss of balance 0.000
tremor 0.000
exhaustion 0.000
halitosis 0.000
male subfertility 0.000
forgetfulness 0.000
hyperemesis 0.000
chorea 0.000
loss of taste 0.000
acidity 0.000
sore throat 0.000
motor symptom 0.000
hypercapnia 0.000
hyperesthesia 0.000
abdominal cramps 0.000
Decreased activity 0.000
ataxic gait 0.000
ketonuria 0.000
personality change 0.000
cerebellar ataxia 0.000
bitter taste 0.000
tachypnea 0.000
erythema 0.000
physical appearance 0.000
despair 0.000
menopausal symptoms 0.000
vomiting 0.000
clubbing 0.000
DNA marker 0.000
otalgia 0.000
eds 0.000
muscle rigidity 0.000
hepatosplenomegaly 0.000
catatonia 0.000
urinary frequency 0.000
abnormal gait 0.000
decreased appetite 0.000
fatigue 0.000
more...
Drug
ROS 0.002
CED 0.000
Arsenic trioxide 0.000
AMC 0.000
Edratide 0.000
Lexatumumab 0.000
3-Methyladenine 0.000
Emodin 0.000
Bortezomib 0.000
Teroxirone 0.000
TTC 0.000
Emodin 0.000
Alsterpaullone 0.000
Scutellaria root 0.000
Simvastatin 0.000
Purvalanol 0.000
Alisma rhizome 0.000
Condurango 0.000
Etoposide 0.000
Taxol 0.000
PFT 0.000
Propidium 0.000
p75 0.000
Glycyrrhiza 0.000
MAP 0.000
Sorafenib 0.000
NVP 0.000
Mapatumumab 0.000
Ethanol 0.000
CA-074 0.000
Ulinastatin 0.000
Flavopiridol 0.000
Advexin 0.000
Saccharin sodium 0.000
P-Nitrophenol 0.000
vitamin E 0.000
Ginseng 0.000
Monit 0.000
Epigallocatechin 0.000
ascorbate 0.000
Rutin 0.000
2-Methoxyestradiol 0.000
Montirelin 0.000
Propofol 0.000
Glutathione 0.000
7,8-Dihydroneopterin 0.000
2-Iminobiotin 0.000
Imatinib 0.000
TAT 0.000
Diammonium glycyrrhizinate 0.000
Tandutinib 0.000
MRC 0.000
CPT-11 0.000
Heme 0.000
Alexidine 0.000
Myricetin 0.000
Fipronil 0.000
ADR 0.000
Gefitinib 0.000
Areca 0.000
Bupleurum root 0.000
Angelica dahurica root 0.000
Balhimycin 0.000
Cassia seed 0.000
Hyperforin 0.000
Epothilone B 0.000
Mevastatin 0.000
Docetaxel 0.000
Cilostazol 0.000
Sodium metabisulfite 0.000
Avasimibe 0.000
Cilengitide 0.000
Proflavin 0.000
Zedoary 0.000
Lemon oil 0.000
Phosphatidylserine 0.000
Limaprost 0.000
3-Methoxybenzamide 0.000
Liraglutide 0.000
ICI 0.000
more...
Enzyme
caspase-3 1.000
caspase-9 0.082
caspase-8 0.039
PARP 0.023
caspase-7 0.009
caspase-7 0.009
caspase-6 0.004
mitogen-activated protein kinase 0.003
caspase-6 0.003
caspase-2 0.003
caspase-2 0.003
caspase-1 0.002
superoxide dismutase 0.002
lactate dehydrogenase 0.001
catalase 0.001
caspase-4 0.001
caspase-10 0.001
caspase-10 0.001
caspase-4 0.001
glutathione peroxidase 0.000
TdT 0.000
ERK 0.000
protein kinase 0.000
GSK 0.000
phosphatidylinositol 3-kinase 0.000
MPP 0.000
Omi/HtrA2 0.000
cdc2 0.000
MEK 0.000
alanine aminotransferase 0.000
aspartate aminotransferase 0.000
phosphoinositide 3-kinase 0.000
proteasome 0.000
mu-calpain 0.000
m-calpain 0.000
AMP-activated protein kinase 0.000
luciferase 0.000
granzyme B 0.000
focal adhesion kinase 0.000
NADPH oxidase 0.000
protein kinase C 0.000
caspase-11 0.000
caspase-11 0.000
NADPH oxidase 0.000
MMP 0.000
cathepsin B 0.000
AMPK 0.000
heme oxygenase 0.000
creatine kinase 0.000
AST 0.000
glutathione reductase 0.000
AMPK 0.000
peroxidase 0.000
tyrosine hydroxylase 0.000
complex I 0.000
caspase-5 0.000
IKK 0.000
cathepsin D 0.000
NO synthase 0.000
neutral sphingomyelinase 0.000
topoisomerase 0.000
calcineurin 0.000
topoisomerase 0.000
P-glycoprotein 0.000
glutathione S-transferase 0.000
caspase-5 0.000
MAP 0.000
holocytochrome c synthetase 0.000
NQO1 0.000
NOS 0.000
MEKK1 0.000
sphingosine kinase 0.000
DNA ligase 0.000
DNA ligase 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
acetylcholinesterase 0.000
ATPase 0.000
aconitase 0.000
thioredoxin reductase 0.000
PDK1 0.000
more...
Compound
dUTP 0.006
MTT 0.005
ADP-ribose 0.002
oxygen 0.002
DNA 0.002
TNF 0.001
GSH 0.001
GSH 0.001
MDA 0.001
Hoechst 33342 0.001
N-acetylcysteine 0.001
iodine 0.000
Asp 0.000
Cyt 0.000
cysteine 0.000
DDP 0.000
bromide 0.000
MPP 0.000
MPP 0.000
Cytochrome c 0.000
nitric oxide 0.000
Curcumin 0.000
H2O2 0.000
acridine 0.000
DCB 0.000
Oridonin 0.000
MTS 0.000
DCB 0.000
glucose 0.000
ADR 0.000
DCB 0.000
Resveratrol 0.000
ATP 0.000
Tanshinone 0.000
8-OHdG 0.000
DCB 0.000
MEK 0.000
Quercetin 0.000
Adriamycin 0.000
DCB 0.000
calcium 0.000
Neuronal 0.000
Berberine 0.000
Ursolic acid 0.000
ADP 0.000
diacetate 0.000
CMK 0.000
Matrine 0.000
Matrine 0.000
Matrine 0.000
Dec 0.000
ATF 0.000
glutamate 0.000
Staurosporine 0.000
CAT 0.000
CAT 0.000
Baicalein 0.000
hydrogen 0.000
Staurosporine 0.000
Puerarin 0.000
ADP 0.000
ADP 0.000
NOXA 0.000
CAT 0.000
Bongkrekic acid 0.000
Chrysin 0.000
Sulforaphane 0.000
Baicalin 0.000
Apigenin 0.000
Hematoxylin 0.000
GSSG 0.000
alanine 0.000
Bufalin 0.000
Silymarin 0.000
serine 0.000
Luteolin 0.000
dATP 0.000
Triptolide 0.000
Diallyl disulfide 0.000
Diallyl disulfide 0.000
more...