Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.22.56 (caspase-3)
35,750 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein caspase-3 35429 Bcl-2 7976 caspase-9 4746 cytochrome c 4160 p53 3259 Mol 3217 caspase-8 3202 PARP 3025 Sep 2325 annexin V 1657 p38 1586 Fas 1553 TNF 1552 tumor necrosis factor 1448 superoxide dismutase 1359 GSH 1239 JNK 1138 poly(ADP-ribose) polymerase 1130 p21 1105 ROS 1073 MAPK 1016 PI3K 1002 endoplasmic reticulum 986 catalase 975 lactate dehydrogenase 915 cytokine 900 ERK 885 AKT 884 cytochrome 851 ERK1 850 ATP 825 bcl-2 812 IL-6 780 Bid 700 inducible nitric oxide synthase 668 survivin 650 mTOR 641 poly (ADP-ribose) polymerase 625 cyclin D1 620 glutathione peroxidase 618 CPP32 612 c-Jun 596 insulin 589 p65 554 bax 552 anti-apoptotic protein 525 lipopolysaccharide 524 proliferating cell nuclear antigen 521 LC3 519 calpain 467 XIAP 464 SOD 464 extracellular signal-regulated kinase 441 Mcl-1 430 BAX 427 LDH 418 proteasome 415 Bax protein 410 Fas ligand 396 Bak 388 kit 387 collagen 385 p27 376 vascular endothelial growth factor 373 heme oxygenase-1 372 inhibitor of apoptosis 365 FasL 363 apoptosis-inducing factor 355 TNF-alpha 353 PARP-1 344 protein kinase B 343 phosphatidylinositol 3-kinase 342 cyclooxygenase-2 335 CHOP 335 mitogen-activated protein 325 pro-apoptotic protein 324 COX-2 319 catenin 318 Nrf2 316 ADP 314 more...

Disease cancer 7334 tumor 4651 ischemia 1568 GSH 1240 leukemia 1173 tumor growth 1128 breast cancer 1126 carcinoma 1039 hepatocellular carcinoma 1013 Alzheimer's disease 886 B-cell lymphoma 766 MCF 763 diabetes 740 neuroblastoma 670 lung cancer 653 colon cancer 651 stroke 594 Parkinson's disease 586 prostate cancer 586 cerebral ischemia 552 melanoma 525 adenocarcinoma 518 colorectal cancer 432 carcinogenesis 432 tumorigenesis 412 gastric cancer 387 glioma 383 lymphoma 369 squamous cell carcinoma 335 ovarian cancer 328 osteosarcoma 318 cervical cancer 301 myocardial ischemia 282 non-small cell lung cancer 282 glioblastoma 280 pancreatic cancer 251 liver cancer 246 multiple myeloma 244 atherosclerosis 237 myocardial infarction 234 hyperglycemia 229 sepsis 226 sepsis 220 acute promyelocytic leukemia 217 tumor progression 209 cognitive impairment 208 acute myeloid leukemia 199 liver cancer 194 DDP 194 chronic myeloid leukemia 190 lung carcinoma 180 heart failure 177 pheochromocytoma 174 bladder cancer 161 type 2 diabetes 157 HIV 156 retinoblastoma 151 depression 147 virus infection 142 hypertension 139 osteoarthritis 133 ATM 133 dementia 130 obesity 127 metastases 127 MTS 127 Huntington's disease 125 AGS 121 memory impairment 118 cold 115 rheumatoid arthritis 113 subarachnoid hemorrhage 113 acute lymphoblastic leukemia 113 cardiovascular disease 113 amyotrophic lateral sclerosis 112 diabetic nephropathy 111 skin cancer 109 brain edema 107 SCID 106 Blocking 102 more...

Symptom collapse 252 seizures 168 starvation 150 functional recovery 137 anesthesia 113 pain 92 hypothermia 71 hyperoxia 61 diarrhea 61 respiratory distress 40 weakness 27 memory loss 27 thinning 25 ataxia 21 cachexia 19 skin damage 19 tremor 18 bradykinesia 17 exhaustion 15 acute stress 13 fatigue 12 vomiting 12 acidity 11 HSA 9 headache 8 analgesia 8 erythema 8 hypercapnia 7 cough 7 overweight 7 nausea 7 incoordination 7 dry eye 7 angina 7 abdominal pain 6 neurological disability 6 anorexia 5 back pain 5 Scratch 5 Neuropathic pain 5 cerebellar ataxia 4 splenomegaly 4 stomach pain 4 constipation 4 chorea 4 Anoxia 4 low back pain 4 sore throat 4 insomnia 4 chest pain 3 dizziness 3 hepatosplenomegaly 3 hepatomegaly 3 hypotonia 3 tachypnea 3 POA 3 dystonia 3 dyspnea 3 lethargy 2 menopausal symptoms 2 physical appearance 2 forgetfulness 2 Tenderness 2 spasticity 2 pelvic pain 2 Motor dysfunction 2 loss of balance 2 tinnitus 2 disturbed balance 2 bitter taste 2 halitosis 2 acute pain 2 despair 2 catatonia 1 startle reaction 1 paraparesis 1 eds 1 loss of taste 1 agitation 1 chronic constipation 1 more...

Drug ROS 1073 Monit 151 ascorbate 120 MAP 112 vitamin E 107 Dermatol 104 lysine 103 Cardiovasc 97 IFN-gamma 96 IL-2 92 Ethanol 84 Arsenic trioxide 73 AMC 66 CED 64 CSF 59 p75 56 Taxol 53 Glutathione 51 caffeine 47 TTC 46 CTX 45 Bortezomib 43 ICI 41 Simvastatin 40 Indomethacin 40 MRC 38 ZnO 36 Heme 36 Sorafenib 34 Imatinib 34 Glycyrrhiza 33 TAT 32 Propofol 32 Ginseng 32 Etoposide 32 EE2 31 Angiotensin II 31 NADH 30 CPT-11 28 Adriamycin 28 Fluorescein 28 NVP 27 ADR 27 Mutagen 25 Emodin 25 Emodin 25 ADM 25 Docetaxel 24 Parkin 23 -deoxyadenosine 23 Parkin 23 Vitamin E 22 ALA 21 Gefitinib 20 PFT 20 CTX 19 CTX 19 Rutin 19 Lovastatin 18 Leaf 18 3-Methyladenine 17 Gel 16 Epigallocatechin 16 Oxaliplatin 16 Nitric Oxide 16 BH4 16 Gleevec 15 Ouabain 15 CoCl2 15 CoCl2 15 Glucagon 15 citric acid 14 Photofrin 14 Propidium 14 Phosphatidylserine 14 lactose 14 CCL 13 IFN-beta 13 ABC 13 DNase I 13 more...

Enzyme caspase-3 35750 caspase-9 4691 mitogen-activated protein kinase 3450 PARP 3345 caspase-8 3091 superoxide dismutase 1778 ERK 1219 catalase 1117 protein kinase 1071 lactate dehydrogenase 937 caspase-1 741 glutathione peroxidase 626 caspase-7 551 caspase-7 532 alanine aminotransferase 433 protein kinase C 430 proteasome 424 focal adhesion kinase 422 luciferase 410 MEK 382 aspartate aminotransferase 374 peroxidase 343 phosphatidylinositol 3-kinase 342 GSK 305 caspase-2 298 caspase-2 289 cdc2 270 caspase-6 252 AMP-activated protein kinase 243 caspase-6 231 creatine kinase 212 NADPH oxidase 206 phosphoinositide 3-kinase 194 NADPH oxidase 192 ATPase 184 TdT 180 tyrosine hydroxylase 157 glutathione S-transferase 156 AMPK 153 glutathione reductase 144 NO synthase 144 calcineurin 142 AMPK 140 MPP 136 alkaline phosphatase 135 acetylcholinesterase 126 P-glycoprotein 122 MMP 120 complex I 120 AST 119 granzyme B 118 cathepsin B 114 topoisomerase 110 heme oxygenase 101 topoisomerase 101 caspase-4 89 collagenase 88 MAP 86 caspase-4 84 endonuclease 83 IKK 82 ACS 81 reverse transcriptase 80 NOS 77 NQO1 76 cathepsin D 75 m-calpain 66 thrombin 66 mu-calpain 61 caspase-10 60 phospholipase C 60 caspase-10 59 phosphodiesterase 58 phospholipase A2 58 trypsin 56 Omi/HtrA2 55 xanthine oxidase 50 succinate dehydrogenase 50 DNase 49 RNase 47 more...

Compound DNA 6730 oxygen 4966 Dec 2510 MTT 2292 TNF 1552 glucose 1324 GSH 1266 GSH 1266 dUTP 1263 calcium 1090 water 1012 nitric oxide 961 cysteine 950 iodine 898 MDA 859 ATP 825 hydrogen 740 Asp 716 bromide 685 ADP-ribose 662 sodium 613 Clin 568 N-acetylcysteine 508 glutamate 459 H2O2 453 ethanol 438 alanine 406 serine 382 tyrosine 379 ADP 368 nitrogen 359 creatinine 348 urea 324 ADP 315 ADP 314 zinc 300 DDP 291 phosphate 261 iron 243 arginine 243 Hoechst 33342 240 Curcumin 239 MEK 238 galactose 222 acetate 221 acridine 213 threonine 209 Neuronal 200 Cyt 195 Adriamycin 187 ADR 186 potassium 184 cadmium 181 cAMP 179 retinoic acid 168 aldehyde 162 aldehyde 159 copper 157 CAT 155 NH2 155 CAT 155 CAT 155 sulfate 154 Resveratrol 152 NAD 146 lysine 145 THP 144 THP 144 boron 143 diacetate 141 selenium 141 Panam 140 MPP 136 MPP 136 Cytochrome c 136 fluorine 131 leucine 130 MTS 127 NAD 127 8-OHdG 124 more...

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